Kelun-Biotech's TROP2 ADC Significantly Improves Lung Cancer Survival
Written by Emily J. Thompson, Senior Investment Analyst
Updated: May 22 2026
0mins
Kelun-Biotech reported that its TROP2-directed ADC sacituzumab tirumotecan combined with pembrolizumab showed a statistically significant and clinically meaningful improvement in progression-free survival versus pembrolizumab alone in first-line PD-L1-positive metastatic NSCLC, alongside a markedly higher response rate, with results selected for oral presentation at ASCO. next-generation RET inhibitor lunbotinib showed high clinical activity in a pivotal Phase II study of RET-fusion positive NSCLC, with ORR of 87.1% in pre-treated and 81.3% in treatment-naive patients, long median PFS, and durable survival signals with 24-month OS rates up to 74.1%, supporting strong efficacy in both treatment settings.
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Analyst Views on MRK
Wall Street analysts forecast MRK stock price to fall
16 Analyst Rating
11 Buy
5 Hold
0 Sell
Moderate Buy
Current: 119.890
Low
95.00
Averages
119.53
High
139.00
Current: 119.890
Low
95.00
Averages
119.53
High
139.00
About MRK
Merck & Co., Inc. is a global health care company that delivers health solutions through its prescription medicines, including biologic therapies, vaccines and animal health products. Its Pharmaceutical segment includes human health pharmaceutical and vaccine products. The Company sells its human health pharmaceutical products primarily to drug wholesalers and retailers, hospitals, government agencies and managed health care providers. It sells these human health vaccines primarily to physicians, wholesalers, distributors and government entities. Its Animal Health segment discovers, develops, manufactures and markets a range of veterinary pharmaceutical and vaccine products, as well as health management solutions and services, for the prevention, treatment and control of disease in all livestock and companion animal species. Its products include KEYTRUDA (pembrolizumab) injection, for intravenous use; WELIREG (belzutifan) tablets, for oral use; Ohtuvayre (ensifentrine) and others.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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See More
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See More
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See More
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See More
