Journey Medical Publishes Phase 1 Trial Results for DFD-29
Journey Medical announced that results from the Phase 1 clinical trial assessing the impact of low-dose oral minocycline, DFD-29, on skin, gastrointestinal and vaginal microflora in healthy adults were published in the Journal of Drugs in Dermatology, a leading peer-reviewed publication in clinical dermatology. The clinical trial also assessed the safety and tolerability of the treatment. The results indicate that DFD-29 administration for 16 weeks had no detectable effects on skin, GI tract or vaginal microflora and it was well tolerated in healthy adults, supporting its use as a therapeutic option for patients with moderate-to-severe rosacea. "We are very pleased to see these important data published in the Journal of Drugs in Dermatology," said Claude Maraoui, Co-Founder, President and Chief Executive Officer of Journey Medical. "This peer-reviewed validation reinforces the differentiated profile of Emrosi as an effective, low-dose oral treatment for rosacea that does not meaningfully disrupt the normal microbiota or contribute to antibiotic resistance. These results, along with the robust safety and efficacy data seen throughout all of our clinical trials, further support Emrosi's potential for long-term use and underscore our commitment to bringing safe, innovative dermatology treatments to patients."
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Journey Medical (DERM) Q3 Earnings: Analyzing Key Metrics Against Estimates
Journey Medical Corporation Financial Performance: For Q3 2025, Journey Medical Corporation reported a revenue of $17.63 million, a 20.5% increase year-over-year, but fell short of the Zacks Consensus Estimate by 0.39%. The EPS was -$0.09, slightly better than the previous year's -$0.12 but below the consensus estimate of -$0.08.
Investor Insights: Investors are closely monitoring revenue and earnings changes to gauge the company's financial health, with key metrics providing a clearer picture of performance compared to year-ago numbers and analyst estimates.
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Journey Medical Corporation Presents Efficacy Data Analysis from Combined Emrosi™ (DFD-29) Phase 3 Clinical Trial at the 2025 Fall Clinical Dermatology Conference
FDA Approval and Efficacy: Emrosi (40 mg Minocycline Hydrochloride Modified-Release Capsules) is FDA-approved for treating inflammatory lesions of rosacea in adults, showing superior efficacy in clinical trials compared to both placebo and doxycycline.
Clinical Trial Results: In a pooled analysis of two Phase 3 trials, 62.7% of subjects treated with DFD-29 achieved treatment success, significantly outperforming the 39.0% success rate of Oracea and 28.2% for placebo, with notable reductions in inflammatory lesions.
Safety Profile: DFD-29 was well tolerated in trials, with no major safety issues reported, and the incidence of treatment-emergent adverse events was comparable across all treatment groups.
Market Position and Commitment: Journey Medical Corporation aims to expand Emrosi's market presence, emphasizing its potential as a standard treatment for rosacea and its commitment to improving patient outcomes in dermatology.
