Iridex Study Shows 25%-35% IOP Reduction in Glaucoma Patients Using MicroPulse Technology
Iridex announced a recently published independent, retrospective study in Ophthalmology and Therapy. The study demonstrates that retreatment of transscleral laser treatment using MicroPulse technology can safely and effectively further reduce intraocular pressure, or IOP, in patients with glaucoma. The study aimed to assess the effectiveness, repeatability, and safety of retreatment in real-world clinical practice using MicroPulse TLT. Three months after retreatment, all patient groups demonstrated meaningful IOP reductions, ranging from approximately 25% to 35%, regardless of their prior response to the primary treatment. Retreatment timing varied widely across patient groups, reflecting the individualized nature of glaucoma management. On average, patients received their first retreatment as early as approximately 4 months in nonresponders and as late as more than 28 months in patients with late-attrition. Among the subset of patients who required a second retreatment, intervals ranged from about 3 months to nearly 2 years in enhancement cases.
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Iridex's MicroPulse Technology Effectively Lowers Intraocular Pressure in Glaucoma Patients
- Clinical Study Results: An independent study at the University Eye Clinic Maastricht shows that retreatment with MicroPulse laser treatment (MicroPulse TLT) reduces intraocular pressure (IOP) by 25% to 35% in glaucoma patients, demonstrating the technology's effectiveness and safety in glaucoma management.
- Treatment Flexibility: The study involved 76 eyes, with retreatment timing varying from approximately 4 months to over 28 months, showcasing the individualized management capabilities of the technology, allowing for flexible treatment adjustments based on patient responses.
- Success Rate of Repeat Treatments: Results indicate that patients who initially benefited from treatment have higher long-term success rates upon retreatment, aiding clinicians in better identifying candidates for retreatment and optimizing glaucoma management strategies.
- Company Strategic Commitment: Iridex CEO Patrick Mercer stated that the findings further validate MicroPulse TLT as a valuable non-incisional option, reflecting the company's strong commitment to advancing clinical evidence and supporting ophthalmologists in delivering durable outcomes for their patients.

Iridex Publishes Study on Thermal Dynamics of Laser Treatments for Glaucoma
- Research Findings: Iridex's newly published study provides the first quantitative comparison of thermal tissue effects between CW-TSCPC and MicroPulse TLT, revealing that CW-TSCPC creates a 2 mm thermal zone exceeding 100°C for 2.2 seconds, indicating potential risks in glaucoma treatment.
- Technical Advantages: MicroPulse TLT generates a smaller thermal zone of 0.6-1.2 mm with peak temperatures below 100°C, demonstrating its safety and uniform heat distribution, which may offer a safer option for earlier interventions.
- Clinical Significance: The study underscores the thermal continuum between the two techniques, suggesting that with further optimization, they could serve complementary roles in glaucoma management, enhancing treatment diversity.
- Company Commitment: Iridex CEO Patrick Mercer highlighted that this research reflects the company's commitment to evidence-based innovation in glaucoma care, aiming to improve treatment outcomes through a deeper understanding of laser interactions with ocular tissues.









