Dyadic Expands Collaboration with Fermbox Bio
Dyadic Applied BioSolutions announced a significant expansion of its collaboration with Fermbox Bio. This expanded partnership broadens the range of products, platforms, and commercial opportunities the companies will jointly deliver to market. Building on their longstanding relationship, this agreement enables Fermbox Bio to manufacture and commercialize an expanding portfolio of Dyadic-developed proteins and enzymes using both the Dapibus and C1 expression systems. Dyadic will co-commercialize these products globally, strengthening its capacity to bring scalable, animal-free solutions to life science, food and nutrition, and bioindustrial sectors. The agreement also allows both parties to incorporate products developed on Fermbox Bio's proprietary microbial platforms into the joint portfolio, creating a more diverse and competitive pipeline of fermentation-derived biomolecules. Key elements of the expanded collaboration include: Manufacture of multiple Dyadic-origin products by Fermbox Bio, enabling efficient production and market expansion of sustainable, animal-free proteins and enzymes. Dual-Sourcing flexibility, allowing both companies to supply production strains and finished products, produced via C1, Dapibus, or alternative microbial systems. Integration of Fermbox-developed products into the joint commercial portfolio, where mutually agreed. A jointly managed, continuously updated product pipeline, allowing the companies to add new commercial opportunities as markets and customer needs evolve.
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Company Overview: Dyadic International, Inc. is a biotechnology company focused on producing high-value proteins for life sciences, food, and industrial applications using proprietary gene expression platforms.
Upcoming Conferences: Joe Hazelton, President & COO of Dyadic, will present at several upcoming conferences, including the H.C. Wainwright 27th Annual Global Investment Conference and BioProcess International BPI East, to engage with investors and industry partners.
Conference Call Overview: Dyadic International held its Q2 2025 earnings conference call on August 13, 2025, featuring key participants including President Joe Hazelton and CFO Ping Wang Rawson, who provided insights into the company's financial results and strategic direction.
Forward-Looking Statements: The call included forward-looking statements that carry risks and uncertainties, with a disclaimer from Dyadic regarding their obligation to update these projections.
Earnings Report and Strategic Shift: Dyadic International reported Q2 2025 earnings with a GAAP revenue of $967,000, marking a year-over-year increase. The company has undergone a rebranding to Dyadic Applied Biosolutions and shifted its focus from research to commercializing engineered protein platforms in life sciences and bioindustrial markets.
Financial Outlook and Cost Management: The company narrowed its net loss to $1.79 million while managing general and administrative costs effectively. Management anticipates additional revenues from product launches by late 2025 and aims to maintain operating expenses at or below prior-year levels.

Company Transformation: Dyadic International has transitioned from a research-focused entity to a commercially-driven biotechnology firm, rebranding as Dyadic Applied BioSolutions and emphasizing its capabilities in scalable, animal-free protein production for various applications. The company aims to achieve cash flow positivity by the end of 2026.
Financial Performance: In Q2 2025, Dyadic reported a significant revenue increase to $967,000, alongside reduced operational losses, while successfully raising $5.3 million through equity offerings to support product development and commercialization efforts across life sciences and food nutrition sectors.






