Cellectar Biosciences Secures Multi-Year Supply Agreement with Ionetix for Key Radioisotopes
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 16 2025
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Source: Globenewswire
- Strategic Partnership: Cellectar Biosciences has signed a multi-year supply agreement with Ionetix to secure clinical and commercial-scale supplies of Ac-225 and At-211 radioisotopes, which is expected to accelerate the advancement of its targeted alpha therapy candidates in cancer treatment.
- Technological Edge: Cellectar's Phospholipid Drug Conjugate platform technology effectively delivers isotopes directly to tumor cells, with Ac-225 and At-211 providing an ideal high-energy radiation solution for treating challenging solid tumors like pancreatic cancer, enhancing therapeutic efficacy.
- Production Capacity Expansion: Ionetix is installing a second cyclotron at its Michigan facility dedicated to commercial-scale production of Ac-225 and At-211, ensuring it meets the growing market demand and supports Cellectar's next-generation targeted therapies.
- Market Outlook: This collaboration not only provides Cellectar with a reliable isotope supply but also drives innovation in cancer treatment, which is anticipated to significantly enhance the company's competitiveness and market share in the biopharmaceutical sector.
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About CLRB
Cellectar Biosciences, Inc. is a late-stage clinical biopharmaceutical company. The Company is focused on the discovery, development, and commercialization of drugs for treatment of cancer. The Company, through its phospholipid ether drug conjugate (PDC) delivery platform, is focused on developing PDCs that are designed to specifically target cancer cells. Its PDC platform possesses the potential for the discovery and development of cancer-targeting treatments, and it plans to develop PDCs both independently and through research and development collaborations. Its lead programs are: Iopofosine I 131 (iopofosine), a beta-emitting iodine-131-based program which has been studied extensively; CLR 121225, an actinium-225-based program; and CLR 121125, an iodine-125 Auger-emitting program. Iopofosine evaluation is ongoing in a Phase IIb study in r/r multiple myeloma and central nervous system lymphoma patients and the CLOVER-2 Phase Ib study for pediatric patients with high grade gliomas.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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