Cassava Sciences Publishes Alzheimer's Clinical Trial Article
Cassava Sciences announced publication of the article Phase 3 randomized clinical trials of simufilam in mild-to-moderate Alzheimer's disease in an upcoming issue of the Journal of Prevention of Alzheimer's Disease, JPAD. The paper provides a detailed analysis of data from two Phase 3 clinical trials, RETHINK-ALZ and REFOCUS-ALZ. While, as previously disclosed, the two studies did not meet their pre-specified co-primary, secondary, or exploratory biomarker endpoints, exploratory post-hoc analysis of the studies offers informative insights. "In keeping with our commitment to report the detailed results, we are pleased to make the data from the RETHINK-ALZ and REFOCUS-ALZ studies available to the Alzheimer's disease scientific community through publication in the highly respected Journal of Prevention of Alzheimer's Disease. We hope the paper can serve as a foundation for further research in the field," said Rick Barry, President and Chief Executive Officer of Cassava. "The detailed safety observations reported in the article provide heartening encouragement for our ongoing development program in TSC-related epilepsy, as we work to initiate a proof-of-concept study in collaboration with leading investigators."
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Cassava Technologies and AXON Networks Form Strategic Partnership
- Strategic Partnership Announcement: Cassava Technologies and AXON Networks unveiled their strategic partnership at the Counder Conference in Cape Town, aiming to co-develop Africa's first end-to-end Operator-as-a-Service (OaaS) platform to drive digital transformation through AI-driven network solutions.
- Infrastructure Enhancement: The OaaS platform will leverage Cassava's extensive 110,000 km fiber network to deliver secure, high-speed data infrastructure, significantly enhancing the agility and intelligence of mobile network operators and ISPs, thereby fostering economic growth and innovation.
- AI-Driven Digital Twin Technology: AXON's Digital Twin technology will transform networks into self-learning, self-optimizing systems, reducing operational complexity, accelerating service delivery, and ensuring resilient connectivity at scale, thus providing customers with more efficient service experiences.
- Market Potential Unleashed: This collaboration will not only provide a robust digital foundation for African businesses but also promote widespread AI adoption, helping enterprises gain competitive advantages in the global market and showcasing Africa's immense potential in the digital economy.

Cassava Sciences Faces Shareholder Rights Investigation by Halper Sadeh LLC
- Shareholder Rights Investigation: Halper Sadeh LLC is investigating whether certain officers and directors of Cassava Sciences, Inc. breached their fiduciary duties to shareholders, potentially impacting corporate governance and shareholder rights.
- Legal Relief Options: Long-term shareholders of Cassava stock may have the opportunity to seek corporate governance reforms, return of funds, or court-approved financial incentive awards, which could directly affect shareholder financial interests and company transparency.
- Importance of Participation: Shareholder involvement can help improve company policies and oversight mechanisms, thereby enhancing management efficiency and transparency, ultimately increasing shareholder value.
- Global Investor Representation: Halper Sadeh LLC represents investors worldwide who have fallen victim to securities fraud and corporate misconduct, having successfully implemented corporate reforms and recovered millions for defrauded investors, demonstrating its capability in protecting investor rights.









