BriaCell Therapeutics Prices $30 Million Offering Amid 53.75% Stock Plunge
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 14 2026
0mins
Should l Buy BCTX?
Source: Benzinga
- Capital Raise: BriaCell Therapeutics successfully priced a $30 million public offering at $5.59 per unit during after-hours trading on Tuesday, issuing 5.37 million units to support its cancer immunotherapy development.
- Clinical Trial Progress: The company reported that a 78-year-old breast cancer patient achieved a complete 100% resolution of lung metastasis after treatment with Bria-OTS, demonstrating the therapy's potential and providing critical data for future studies.
- Market Reaction: Despite positive clinical data, BriaCell's stock plummeted 53.75% to $5.05 in premarket trading on Wednesday, marking a new 52-week low, reflecting market concerns about the company's future prospects.
- Research Phase Update: The Phase 1 dose escalation of Bria-OTS is complete, and the Phase 2a portion is underway, evaluating the combination therapy with immune checkpoint inhibitors, indicating the company's ongoing exploration and innovation in cancer treatment.
Trade with 70% Backtested Accuracy
Stop guessing "Should I Buy BCTX?" and start using high-conviction signals backed by rigorous historical data.
Sign up today to access powerful investing tools and make smarter, data-driven decisions.
Analyst Views on BCTX
About BCTX
BriaCell Therapeutics Corp. is a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care. Bria-IMT, its Phase 3 lead candidate, is a patented, off-the-shelf, cell-based, targeted immunotherapy that activates the patient’s immune system to specifically kill cancer cells without harming other cells. The Company is advancing its Bria-IMT targeted immunotherapy in combination with an immune check point inhibitor (Retifanlimab) in a pivotal Phase 3 study in metastatic breast cancer. It is also developing personalized off-the-shelf immunotherapies, Bria-OTS and Bria-OTS+, which provides a platform technology to develop personalized off-the-shelf immunotherapies for numerous types of cancer, and a soluble CD80 protein therapeutic which act both as a stimulator of the immune system, as well as an immune checkpoint inhibitor. Its pipeline also includes Bria-IMT + CPI, Bria-BRES/BRES+, Bria-PROS+, Bria-LUNG+ and Bria-MEL+.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
BriaCell's Phase 3 Study Receives Fifth Positive DSMB Recommendation
- Safety Confirmation: The independent Data Safety Monitoring Board (DSMB) has issued its fifth consecutive positive recommendation for BriaCell's Phase 3 Bria-ABC study, indicating no safety concerns with the Bria-IMT regimen combined with immune checkpoint inhibitors, thereby bolstering investor confidence in the therapy.
- FDA Fast Track Designation: The study is being conducted under the FDA's Fast Track designation, highlighting the significant unmet medical need in metastatic breast cancer, which suggests that BriaCell is positioned to capitalize on substantial market opportunities in this area.
- Clinical Progress Outlook: BriaCell's CEO, William V. Williams, emphasized that the ongoing support from the DSMB will facilitate the advancement of the Bria-IMT regimen, aiming to provide new hope for patients with limited treatment options, showcasing the company's commitment to innovative therapies.
- Regular Review Mechanism: The DSMB meets quarterly to ensure the safety and efficacy of the study, and the continuous positive feedback not only enhances the credibility of the research but also adds significant weight to BriaCell's reputation in the biotechnology sector.
See More
BriaCell Treatment Shows Significant Efficacy in Cancer Patients
- Significant Clinical Efficacy: The Bria-IMT treatment achieved complete resolution of right temporal lobe metastasis in a 66-year-old female patient, who survived 27 months post-enrollment, demonstrating the therapy's potential in heavily pre-treated patients.
- Evidence of Immune Activation: CD8 ImmunoPET imaging revealed a significant increase in CD8+ T cells in the cervical lymph nodes post-Bria-IMT treatment, indicating immune system activation that may contribute to long-term survival.
- Study Scale and Results: Among 54 heavily pre-treated metastatic breast cancer patients, 37 received the Bria-IMT regimen, with no reported treatment discontinuations related to Bria-IMT to date, indicating good safety and tolerability of the therapy.
- Future Research Prospects: The ongoing Phase 3 clinical trial (NCT06072612) by BriaCell will further validate the efficacy of Bria-IMT, potentially bringing new hope to cancer treatment.
See More
BriaCell's New Therapy Significantly Extends Survival in Breast Cancer Patients
- Impressive Survival Data: As of the latest assessment, nine patients treated with Bria-IMT since 2022 have survived over 18 months, significantly exceeding benchmarks for standard therapies, indicating the potential efficacy of this treatment.
- Strong Treatment Continuity: No Bria-IMT-related discontinuations have been reported to date, suggesting good tolerability of the regimen among patients, which may provide new treatment options for heavily pre-treated individuals.
- Clinical Trial Progress: The Bria-IMT regimen continues under Fast Track Designation from the US FDA, expected to offer more effective treatment options for late-stage breast cancer patients, addressing the urgent market need for new therapies.
- Future Research Directions: BriaCell's ongoing pivotal Phase 3 study will focus on overall survival as its primary endpoint, aiming to further validate the efficacy of Bria-IMT and promote its broader acceptance in clinical applications.
See More
U.S. Retail Sales Rise 0.6% MoM, Tech Stocks Decline
- Retail Sales Surge: U.S. retail sales increased by 0.6% month-over-month in November, marking the largest surge since July, indicating a potential rebound in consumer spending that could positively impact economic recovery.
- Tech Stock Decline: Information technology stocks fell by 1.3% on Wednesday, reflecting market concerns over the tech sector, which may affect investor confidence and lead to capital outflows.
- High-Risk Stock Surge: High Roller Technologies, Inc. (NYSE:ROLR) shares skyrocketed 289% to $13.64 after announcing a binding Letter of Intent with Crypto.com to launch an event-based prediction markets product in the U.S., demonstrating strong market demand for innovative offerings.
- IPO Impact: Briacell Therapeutics Corp. (NASDAQ:BCTX) priced its $30 million public offering at $5.59 per unit, leading to a 53% drop in its stock price to $5.09, reflecting market sensitivity to financing activities.
See More
Bank of America Reports Q4 Net Income of $7.6 Billion, Exceeding Expectations
- Earnings Highlight: Bank of America (BAC) reported a net income of $7.6 billion for Q4 FY2025, down from $6.8 billion a year ago, yet its EPS of 98 cents surpassed the analyst consensus estimate of 96 cents, indicating stable profitability amidst market fluctuations.
- Revenue Growth: The bank's revenue net of interest expense increased by 7% year-over-year to $28.532 billion, exceeding the analyst consensus estimate of $27.944 billion, reflecting strong performance and effective cost management in a competitive landscape.
- Market Dynamics: While U.S. stocks traded lower overall, with the Nasdaq Composite falling over 100 points, energy stocks rose by 0.9%, indicating a divergence in market performance that may present investors with opportunities to reassess their portfolios.
- Economic Indicators: U.S. retail sales increased by 0.6% month-over-month in November, marking the largest surge since July, suggesting a rebound in consumer spending that could positively impact future economic growth.
See More
Glaukos Corp (GKOS) Projects FY25 Sales of $507 Million, Shares Drop 12.1%
- Glaukos Sales Projection: Glaukos Corp anticipates FY25 sales of $507 million, yet its shares fell 12.1% in pre-market trading, indicating market concerns about its growth outlook despite the positive sales forecast.
- Briacell's Sharp Decline: Briacell Therapeutics' announcement of a $30 million public offering led to a staggering 53.1% drop in its stock price during pre-market trading, reflecting investor apprehension regarding the financing strategy.
- Trip.com Investigation Impact: Trip.com Group confirmed it is under investigation by China's SAMR for potential anti-monopoly violations, resulting in a 9.3% decline in its pre-market stock price, which may adversely affect its market performance and investor confidence.
- Pearson Trading Update: Pearson PLC's trading update for 2025 caused its shares to drop 7.2% in pre-market trading, indicating a cautious market sentiment regarding its future performance.
See More
BriaCell's Phase 3 Study Receives Fifth Positive DSMB Recommendation
- Safety Confirmation: The independent Data Safety Monitoring Board (DSMB) has issued its fifth consecutive positive recommendation for BriaCell's Phase 3 Bria-ABC study, indicating no safety concerns with the Bria-IMT regimen combined with immune checkpoint inhibitors, thereby bolstering investor confidence in the therapy.
- FDA Fast Track Designation: The study is being conducted under the FDA's Fast Track designation, highlighting the significant unmet medical need in metastatic breast cancer, which suggests that BriaCell is positioned to capitalize on substantial market opportunities in this area.
- Clinical Progress Outlook: BriaCell's CEO, William V. Williams, emphasized that the ongoing support from the DSMB will facilitate the advancement of the Bria-IMT regimen, aiming to provide new hope for patients with limited treatment options, showcasing the company's commitment to innovative therapies.
- Regular Review Mechanism: The DSMB meets quarterly to ensure the safety and efficacy of the study, and the continuous positive feedback not only enhances the credibility of the research but also adds significant weight to BriaCell's reputation in the biotechnology sector.
See More
BriaCell Treatment Shows Significant Efficacy in Cancer Patients
- Significant Clinical Efficacy: The Bria-IMT treatment achieved complete resolution of right temporal lobe metastasis in a 66-year-old female patient, who survived 27 months post-enrollment, demonstrating the therapy's potential in heavily pre-treated patients.
- Evidence of Immune Activation: CD8 ImmunoPET imaging revealed a significant increase in CD8+ T cells in the cervical lymph nodes post-Bria-IMT treatment, indicating immune system activation that may contribute to long-term survival.
- Study Scale and Results: Among 54 heavily pre-treated metastatic breast cancer patients, 37 received the Bria-IMT regimen, with no reported treatment discontinuations related to Bria-IMT to date, indicating good safety and tolerability of the therapy.
- Future Research Prospects: The ongoing Phase 3 clinical trial (NCT06072612) by BriaCell will further validate the efficacy of Bria-IMT, potentially bringing new hope to cancer treatment.
See More
BriaCell's New Therapy Significantly Extends Survival in Breast Cancer Patients
- Impressive Survival Data: As of the latest assessment, nine patients treated with Bria-IMT since 2022 have survived over 18 months, significantly exceeding benchmarks for standard therapies, indicating the potential efficacy of this treatment.
- Strong Treatment Continuity: No Bria-IMT-related discontinuations have been reported to date, suggesting good tolerability of the regimen among patients, which may provide new treatment options for heavily pre-treated individuals.
- Clinical Trial Progress: The Bria-IMT regimen continues under Fast Track Designation from the US FDA, expected to offer more effective treatment options for late-stage breast cancer patients, addressing the urgent market need for new therapies.
- Future Research Directions: BriaCell's ongoing pivotal Phase 3 study will focus on overall survival as its primary endpoint, aiming to further validate the efficacy of Bria-IMT and promote its broader acceptance in clinical applications.
See More
U.S. Retail Sales Rise 0.6% MoM, Tech Stocks Decline
- Retail Sales Surge: U.S. retail sales increased by 0.6% month-over-month in November, marking the largest surge since July, indicating a potential rebound in consumer spending that could positively impact economic recovery.
- Tech Stock Decline: Information technology stocks fell by 1.3% on Wednesday, reflecting market concerns over the tech sector, which may affect investor confidence and lead to capital outflows.
- High-Risk Stock Surge: High Roller Technologies, Inc. (NYSE:ROLR) shares skyrocketed 289% to $13.64 after announcing a binding Letter of Intent with Crypto.com to launch an event-based prediction markets product in the U.S., demonstrating strong market demand for innovative offerings.
- IPO Impact: Briacell Therapeutics Corp. (NASDAQ:BCTX) priced its $30 million public offering at $5.59 per unit, leading to a 53% drop in its stock price to $5.09, reflecting market sensitivity to financing activities.
See More
Bank of America Reports Q4 Net Income of $7.6 Billion, Exceeding Expectations
- Earnings Highlight: Bank of America (BAC) reported a net income of $7.6 billion for Q4 FY2025, down from $6.8 billion a year ago, yet its EPS of 98 cents surpassed the analyst consensus estimate of 96 cents, indicating stable profitability amidst market fluctuations.
- Revenue Growth: The bank's revenue net of interest expense increased by 7% year-over-year to $28.532 billion, exceeding the analyst consensus estimate of $27.944 billion, reflecting strong performance and effective cost management in a competitive landscape.
- Market Dynamics: While U.S. stocks traded lower overall, with the Nasdaq Composite falling over 100 points, energy stocks rose by 0.9%, indicating a divergence in market performance that may present investors with opportunities to reassess their portfolios.
- Economic Indicators: U.S. retail sales increased by 0.6% month-over-month in November, marking the largest surge since July, suggesting a rebound in consumer spending that could positively impact future economic growth.
See More
Glaukos Corp (GKOS) Projects FY25 Sales of $507 Million, Shares Drop 12.1%
- Glaukos Sales Projection: Glaukos Corp anticipates FY25 sales of $507 million, yet its shares fell 12.1% in pre-market trading, indicating market concerns about its growth outlook despite the positive sales forecast.
- Briacell's Sharp Decline: Briacell Therapeutics' announcement of a $30 million public offering led to a staggering 53.1% drop in its stock price during pre-market trading, reflecting investor apprehension regarding the financing strategy.
- Trip.com Investigation Impact: Trip.com Group confirmed it is under investigation by China's SAMR for potential anti-monopoly violations, resulting in a 9.3% decline in its pre-market stock price, which may adversely affect its market performance and investor confidence.
- Pearson Trading Update: Pearson PLC's trading update for 2025 caused its shares to drop 7.2% in pre-market trading, indicating a cautious market sentiment regarding its future performance.
See More
