ALT Stock Has Dropped Nearly 50% Over the Last Year, Yet Wall Street Predicts Nearly 500% Growth Potential.
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Mar 27 2026
0mins
Source: stocktwits
Stock Price Target: The average 12-month price target for Altimmune (ALT) is $18, indicating a potential upside of 495% from its current trading level of $3.02.
Upcoming Trials: Altimmune is preparing to initiate a late-stage trial of pemvidutide for treating metabolic dysfunction-associated steatotic liver disease (MASLD) in 2026, with expectations to evaluate multiple doses over a 52-week treatment period.
Analyst Ratings: Among analysts covering Altimmune, nine have a 'Buy' or higher rating, while one has a 'Hold' and another a 'Sell' rating, reflecting a generally positive outlook despite recent stock performance.
Retail Sentiment: Retail sentiment around Altimmune's stock has shifted from 'bearish' to 'neutral' in the past 24 hours, although overall messaging volume remains low, indicating mixed investor confidence.
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Analyst Views on ALT
Wall Street analysts forecast ALT stock price to rise
4 Analyst Rating
3 Buy
1 Hold
0 Sell
Strong Buy
Current: 2.930
Low
12.00
Averages
16.00
High
20.00
Current: 2.930
Low
12.00
Averages
16.00
High
20.00
About ALT
Altimmune, Inc. is a late clinical-stage biopharmaceutical company. The Company is developing novel therapies for serious liver diseases. Its lead product candidate, pemvidutide (formerly ALT-801), is a balanced 1:1 glucagon/GLP-1 dual receptor agonist in development for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), alcohol use disorder (AUD) and alcohol-associated liver disease (ALD). The activation of glucagon receptors results in direct effects on the liver, including reductions in liver fat, inflammation and fibrosis, whereas the activation of GLP-1 receptors mediates suppression of appetite and reduction of cravings as well as metabolic effects such as weight loss. It has completed Phase II development of pemvidutide. It also develops and commercializes surfactant-functionalized (EuPort domain) incretin-based peptide therapeutics, including (GLP-1-glucagon)/oxyntomodulin, and variants.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Truist Initiates Coverage on VKTX with Buy Rating and $83 Price Target
- Analyst Rating Boost: Truist has initiated coverage on Viking Therapeutics (VKTX) with a ‘Buy’ rating and an $83 price target, indicating a potential upside of 162% from current levels, reflecting strong market confidence in its growth prospects.
- Weight Loss Market Dynamics: Eli Lilly (LLY) saw its stock price climb nearly 25% over the past month, making it the strongest performer among major obesity drug stocks, highlighting investor recognition of its sustained demand for GLP-1 therapies and market leadership.
- Viking's Competitive Edge: Truist emphasized that Viking's VK2735 drug achieved a 14.7% weight loss in just 13 weeks, with patients continuing to lose weight, showcasing its differentiated competitive advantage in the obesity drug market that could attract more patients.
- Lilly's Market Expansion: Lilly recently announced deals worth up to $3.8 billion with three vaccine developers, further expanding its footprint in infectious diseases and long-term healthcare infrastructure, indicating growth potential beyond its obesity drug portfolio.
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Altimmune to Participate in Upcoming Investor Conferences
- Investor Conference Schedule: Altimmune will participate in the 2026 Jefferies Global Healthcare Conference on June 4, 2026, with a fireside chat at 12:50 PM ET in New York, showcasing its latest advancements in liver disease treatment and attracting investor interest.
- Key Conference Dates: Following this, Altimmune will also attend the Goldman Sachs 47th Annual Global Healthcare Conference on June 10, 2026, with a fireside chat at 8:00 AM ET in Miami Beach, further enhancing the company's visibility among investors.
- Product Development Context: The pemvidutide being developed by Altimmune is a unique dual-action therapy targeting glucagon and GLP-1 receptors in a balanced 1:1 ratio, aimed at treating serious liver diseases such as metabolic dysfunction-associated steatohepatitis, indicating significant market potential.
- Information Access Channels: Investors can access the webcast of the fireside chats via the Events section of the Altimmune website, enhancing interaction with investors and improving transparency and trust.
See More
Altimmune Q1 2026 Earnings Call Insights
- Successful Financing: Altimmune completed an oversubscribed public offering in April, raising $225 million in gross proceeds, resulting in a cash balance of approximately $535 million as of April 30, which provides the company with sufficient funds to support its clinical programs through the critical data readout in 2029.
- Clinical Trial Progress: The company expects to initiate its global Phase III MASH trial, named PERFORMA, in the second half of this year, with data serving as the basis for regulatory submissions in multiple regions, marking a significant milestone in its global development strategy.
- Financial Performance: In Q1 2026, R&D expenses totaled $16.2 million, G&A expenses were $8.1 million, and the net loss amounted to $22.6 million, or $0.18 per share, indicating financial pressure while advancing clinical development.
- Future Outlook: Altimmune plans to report top-line data from the Phase II trial in alcohol use disorder next quarter and expects to complete enrollment for the RESTORE trial in ALD by Q3 2026, demonstrating positive progress across multiple clinical trials and confidence in future growth.
See More
Altimmune Reports Q1 2026 Financial Results and Progress on Pemvidutide
- Successful Financing: Altimmune completed an oversubscribed public offering in April, raising $225 million, significantly strengthening its financial foundation with a cash balance of approximately $535 million, ensuring funding for the MASH Phase III clinical trial in 2026.
- Clinical Trial Progress: The company plans to initiate the global Phase III clinical trial for MASH, named PERFORMA, in the second half of 2026, having submitted the final study protocol to the FDA, which is expected to support regulatory submissions across multiple regions, showcasing strategic positioning in liver disease treatment.
- Market Demand Analysis: Market research indicates that pemvidutide demonstrates favorable tolerability and efficacy in MASH patients, expected to address the growing unmet medical needs in this area, further solidifying Altimmune's competitive position in the biopharmaceutical market.
- Future Outlook: Altimmune is focused on executing its strategy, with top-line data from the AUD Phase II trial expected next quarter, further advancing the clinical development of pemvidutide and aiming to create long-term value for shareholders.
See More
SureNano Science Develops Next-Gen GLP-1 Therapy GEP-44
- Significant Market Potential: The global GLP-1 market is projected to reach $190 billion by 2035, and SureNano Science aims to capitalize on this rapidly growing market by developing GEP-44, a next-generation triple agonist that enhances its competitiveness in obesity and metabolic disease treatment.
- Innovative Therapy Development: GEP-44 is designed as a patented metabolic therapy to address the limitations of first-generation GLP-1 drugs, targeting GLP-1 alongside peptide YY receptors Y1 and Y2, which may significantly improve patient tolerability and treatment outcomes, thereby facilitating successful FDA approval.
- Positive Preclinical Data: SureNano's preclinical studies indicate that GEP-44 achieves approximately 15% weight loss compared to 9% with traditional drugs, while also avoiding common side effects like nausea and gastrointestinal discomfort, potentially establishing a competitive edge in the future market.
- Delivery Technology Innovation: SureNano is exploring non-injection delivery technologies, including oral and sublingual methods, to enhance patient accessibility and long-term adherence, a strategy that not only improves patient experience but may also create new commercial opportunities in a competitive landscape.
See More
Altimmune Q1 Earnings Beat Expectations with Strong Cash Position
- Earnings Beat: Altimmune reported a Q1 GAAP EPS of -$0.18, exceeding expectations by $0.07, indicating an improvement in financial performance that could bolster investor confidence.
- Strong Cash Position: As of April 30, 2026, the company had approximately $535 million in cash, cash equivalents, and short-term investments, reflecting the successful completion of a $225 million oversubscribed public offering in April 2026, ensuring ample funding for future growth.
- Market Reaction Analysis: Despite the strong earnings report, market sentiment remains cautious as some analysts downgrade ratings due to uncertainties surrounding the MASH project, which may impact short-term stock performance.
- Future Outlook: Altimmune is contemplating whether it can replicate the stock price surge seen in 2025; while challenges persist, the robust cash flow supports its strategic initiatives, potentially attracting more investor interest.
See More
Truist Initiates Coverage on VKTX with Buy Rating and $83 Price Target
- Analyst Rating Boost: Truist has initiated coverage on Viking Therapeutics (VKTX) with a ‘Buy’ rating and an $83 price target, indicating a potential upside of 162% from current levels, reflecting strong market confidence in its growth prospects.
- Weight Loss Market Dynamics: Eli Lilly (LLY) saw its stock price climb nearly 25% over the past month, making it the strongest performer among major obesity drug stocks, highlighting investor recognition of its sustained demand for GLP-1 therapies and market leadership.
- Viking's Competitive Edge: Truist emphasized that Viking's VK2735 drug achieved a 14.7% weight loss in just 13 weeks, with patients continuing to lose weight, showcasing its differentiated competitive advantage in the obesity drug market that could attract more patients.
- Lilly's Market Expansion: Lilly recently announced deals worth up to $3.8 billion with three vaccine developers, further expanding its footprint in infectious diseases and long-term healthcare infrastructure, indicating growth potential beyond its obesity drug portfolio.
See More
Altimmune to Participate in Upcoming Investor Conferences
- Investor Conference Schedule: Altimmune will participate in the 2026 Jefferies Global Healthcare Conference on June 4, 2026, with a fireside chat at 12:50 PM ET in New York, showcasing its latest advancements in liver disease treatment and attracting investor interest.
- Key Conference Dates: Following this, Altimmune will also attend the Goldman Sachs 47th Annual Global Healthcare Conference on June 10, 2026, with a fireside chat at 8:00 AM ET in Miami Beach, further enhancing the company's visibility among investors.
- Product Development Context: The pemvidutide being developed by Altimmune is a unique dual-action therapy targeting glucagon and GLP-1 receptors in a balanced 1:1 ratio, aimed at treating serious liver diseases such as metabolic dysfunction-associated steatohepatitis, indicating significant market potential.
- Information Access Channels: Investors can access the webcast of the fireside chats via the Events section of the Altimmune website, enhancing interaction with investors and improving transparency and trust.
See More
Altimmune Q1 2026 Earnings Call Insights
- Successful Financing: Altimmune completed an oversubscribed public offering in April, raising $225 million in gross proceeds, resulting in a cash balance of approximately $535 million as of April 30, which provides the company with sufficient funds to support its clinical programs through the critical data readout in 2029.
- Clinical Trial Progress: The company expects to initiate its global Phase III MASH trial, named PERFORMA, in the second half of this year, with data serving as the basis for regulatory submissions in multiple regions, marking a significant milestone in its global development strategy.
- Financial Performance: In Q1 2026, R&D expenses totaled $16.2 million, G&A expenses were $8.1 million, and the net loss amounted to $22.6 million, or $0.18 per share, indicating financial pressure while advancing clinical development.
- Future Outlook: Altimmune plans to report top-line data from the Phase II trial in alcohol use disorder next quarter and expects to complete enrollment for the RESTORE trial in ALD by Q3 2026, demonstrating positive progress across multiple clinical trials and confidence in future growth.
See More
Altimmune Reports Q1 2026 Financial Results and Progress on Pemvidutide
- Successful Financing: Altimmune completed an oversubscribed public offering in April, raising $225 million, significantly strengthening its financial foundation with a cash balance of approximately $535 million, ensuring funding for the MASH Phase III clinical trial in 2026.
- Clinical Trial Progress: The company plans to initiate the global Phase III clinical trial for MASH, named PERFORMA, in the second half of 2026, having submitted the final study protocol to the FDA, which is expected to support regulatory submissions across multiple regions, showcasing strategic positioning in liver disease treatment.
- Market Demand Analysis: Market research indicates that pemvidutide demonstrates favorable tolerability and efficacy in MASH patients, expected to address the growing unmet medical needs in this area, further solidifying Altimmune's competitive position in the biopharmaceutical market.
- Future Outlook: Altimmune is focused on executing its strategy, with top-line data from the AUD Phase II trial expected next quarter, further advancing the clinical development of pemvidutide and aiming to create long-term value for shareholders.
See More
SureNano Science Develops Next-Gen GLP-1 Therapy GEP-44
- Significant Market Potential: The global GLP-1 market is projected to reach $190 billion by 2035, and SureNano Science aims to capitalize on this rapidly growing market by developing GEP-44, a next-generation triple agonist that enhances its competitiveness in obesity and metabolic disease treatment.
- Innovative Therapy Development: GEP-44 is designed as a patented metabolic therapy to address the limitations of first-generation GLP-1 drugs, targeting GLP-1 alongside peptide YY receptors Y1 and Y2, which may significantly improve patient tolerability and treatment outcomes, thereby facilitating successful FDA approval.
- Positive Preclinical Data: SureNano's preclinical studies indicate that GEP-44 achieves approximately 15% weight loss compared to 9% with traditional drugs, while also avoiding common side effects like nausea and gastrointestinal discomfort, potentially establishing a competitive edge in the future market.
- Delivery Technology Innovation: SureNano is exploring non-injection delivery technologies, including oral and sublingual methods, to enhance patient accessibility and long-term adherence, a strategy that not only improves patient experience but may also create new commercial opportunities in a competitive landscape.
See More
Altimmune Q1 Earnings Beat Expectations with Strong Cash Position
- Earnings Beat: Altimmune reported a Q1 GAAP EPS of -$0.18, exceeding expectations by $0.07, indicating an improvement in financial performance that could bolster investor confidence.
- Strong Cash Position: As of April 30, 2026, the company had approximately $535 million in cash, cash equivalents, and short-term investments, reflecting the successful completion of a $225 million oversubscribed public offering in April 2026, ensuring ample funding for future growth.
- Market Reaction Analysis: Despite the strong earnings report, market sentiment remains cautious as some analysts downgrade ratings due to uncertainties surrounding the MASH project, which may impact short-term stock performance.
- Future Outlook: Altimmune is contemplating whether it can replicate the stock price surge seen in 2025; while challenges persist, the robust cash flow supports its strategic initiatives, potentially attracting more investor interest.
See More
