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ALT Overview

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ET
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ET
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Intellectia

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High
3.770
Open
3.770
VWAP
3.68
Vol
748.76K
Mkt Cap
494.27M
Low
3.620
Amount
2.76M
EV/EBITDA(TTM)
--
Total Shares
130.07M
EV
255.10M
EV/OCF(TTM)
--
P/S(TTM)
8.16K
Altimmune, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing next-generation peptide-based therapeutics. It is developing pemvidutide, a GLP-1/glucagon dual receptor agonist for the treatment of obesity, metabolic dysfunction-associated steatohepatitis (MASH) and other indications. Activation of the GLP-1 and glucagon receptors is believed to mimic the complementary effects of diet and exercise on weight loss, with GLP-1 suppressing appetite and glucagon increasing energy expenditure. Glucagon is also recognized as having direct effects on hepatic fat metabolism, to rapid reductions in levels of liver fat and serum lipids. The Company has completed the MOMENTUM Phase II obesity trial and is being studied in the IMPACT Phase IIb MASH trial. The Company also develops and commercializes surfactant-functionalized (EuPort domain) incretin-based peptide therapeutics, including (GLP-1-glucagon)/oxyntomodulin, and variants.
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Events Timeline

(ET)
2026-03-05
07:20:00
Altimmune Reports Q4 Revenue of $26,000
select
2026-02-09 (ET)
2026-02-09
06:20:00
VNET Short Interest Rises to 23.5%
select
2026-01-28 (ET)
2026-01-28
00:40:00
Altimmune to Fund Upcoming Phase 3 Trial
select

News

seekingalpha
9.5
03-05seekingalpha
Altimmune Reports Q4 2025 Earnings and Phase III Trial Plans
  • Clinical Trial Progress: Altimmune plans to initiate a global Phase III MASH trial in 2026, enrolling approximately 1,800 patients to primarily assess the efficacy of pemvidutide at 1.8 mg and 2.4 mg doses, aiming to address significant unmet needs in liver disease.
  • Improved Financial Position: As of year-end 2025, Altimmune reported total cash of $274 million, with a pro forma cash position expected to extend into 2028 following January's fundraising, thereby supporting the advancement of clinical programs.
  • R&D Expense Changes: R&D expenses for Q4 2025 were $18.4 million, a decrease from $19.8 million in the same period of 2024, indicating a strategic adjustment in resource allocation by the company.
  • Positive Market Response: Market research indicated that over 70% of physicians expressed a high likelihood of prescribing pemvidutide, with projected usage rates of 43% and 51% among F2 and F3 patients, respectively, suggesting strong potential acceptance and competitiveness in the market.
stocktwits
9.5
03-05stocktwits
Altimmune's Financial Status and Trial Progress
  • Strong Cash Position: As of the end of February, Altimmune reported cash and cash equivalents of $340 million, which is deemed sufficient to sustain operations into 2028, ensuring stability for upcoming research and trial activities over the next few years.
  • FDA Approval on Trial Design: Altimmune has agreed with the U.S. FDA on the design of the upcoming MASH trial, which is expected to evaluate multiple doses of pemvidutide, supporting potential accelerated approval, indicating the company's strategic positioning in drug development.
  • Disappointing Financial Results: The company reported a net loss of $0.27 per share for Q4, which, while an improvement from $0.33 in the same period of 2024, exceeded Wall Street's estimate of $0.24, leading to a 9% drop in stock price on Thursday, reflecting market concerns over financial performance.
  • Shifting Market Sentiment: Despite the stock decline, retail sentiment on Stocktwits shifted from 'bearish' to 'bullish', with message volume increasing from 'low' to 'normal', indicating investor optimism regarding potential partnerships or buyout opportunities for the company.
seekingalpha
9.0
03-05seekingalpha
Altimmune Announces Late-Stage Trial Plans for Pemvidutide
  • Late-Stage Trial Launch: Altimmune plans to initiate a late-stage trial for metabolic dysfunction-associated steatohepatitis (MASH) in Q4 2025, aiming to evaluate multiple doses of pemvidutide over 52 weeks with biopsy-based endpoints to support potential accelerated approval.
  • FDA Breakthrough Therapy Designation: Earlier this year, the company received FDA's Breakthrough Therapy Designation for pemvidutide as a treatment for MASH, which boosted Altimmune's stock price, reflecting positive market sentiment towards its R&D progress.
  • Disappointing Financial Results: Despite the positive R&D news, Altimmune reported a GAAP loss per share of $0.27 in Q4, missing analysts' expectations by $0.03, with R&D expenses reaching $18.4 million, exceeding the Bloomberg consensus of $17.4 million, leading to a ~7% drop in stock price.
  • Future Outlook: CEO Jerry Durso highlighted that 2026 will be a pivotal year, particularly with the upcoming initiation of the MASH Phase 3 trial, and despite current financial setbacks, the company is actively finalizing the study plan to drive product development.
NASDAQ.COM
2.0
03-05NASDAQ.COM
Altimmune (ALT) Q4 2025 Earnings Call Transcript
seekingalpha
9.5
03-05seekingalpha
Altimmune Q4 Earnings Report Analysis
  • Earnings Performance: Altimmune reported a Q4 GAAP EPS of -$0.27, missing expectations by $0.03, indicating challenges in profitability that may affect investor confidence.
  • Revenue Growth: The company achieved Q4 revenue of $30,000, beating expectations by $30,000 and significantly increasing from $5,000 in the same quarter last year, suggesting a rebound in product demand that could lay the groundwork for future performance improvements.
  • Cash Position: As of December 31, 2025, Altimmune's cash, cash equivalents, and short-term investments totaled $274 million, reflecting the company's financial stability, which supports future R&D and operational needs.
  • Financing Activity: The company strengthened its balance sheet through a $75 million registered direct offering in January 2026, providing essential funding for upcoming clinical trials and market expansion efforts.
seekingalpha
9.5
03-04seekingalpha
Altimmune Scheduled to Announce Q4 Earnings on March 5
  • Earnings Announcement: Altimmune is set to announce its Q4 earnings on March 5 before market open, with a consensus EPS estimate of -$0.24, indicating ongoing challenges in profitability.
  • Earnings Estimate Revisions: Over the past three months, Altimmune's EPS estimates have seen two upward revisions with no downward adjustments, reflecting cautious optimism from analysts that could influence investor sentiment.
  • Funding Activity: Altimmune recently priced a $75 million direct offering, which will provide crucial funding to support its R&D projects, particularly in advancing the clinical trials for Pemvidutide.
  • FDA Breakthrough Designation: Altimmune has gained FDA breakthrough designation for its MASH therapy, a development that not only enhances the company's market position but may also expedite the product's path to market, increasing future revenue potential.
Wall Street analysts forecast ALT stock price to rise
4 Analyst Rating
Wall Street analysts forecast ALT stock price to rise
3 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
12.00
Averages
16.00
High
20.00
Current: 0.000
sliders
Low
12.00
Averages
16.00
High
20.00
B. Riley
Buy
downgrade
$18 -> $13
AI Analysis
2026-03-06
Reason
B. Riley
Price Target
$18 -> $13
AI Analysis
2026-03-06
downgrade
Buy
Reason
B. Riley lowered the firm's price target on Altimmune to $13 from $18 and keeps a Buy rating on the shares. Altimmune's Q4 update highlights pemvidutide as a differentiated MASH asset entering Phase 3, supported by a strengthened balance sheet and leadership, the analyst tells investors in a research note. Near-term catalysts include Phase 2 RECLAIM AUD topline data in 3Q26 and a well-aligned Phase 3 registrational design under Subpart-H, with $340M pro-forma cash providing a strong runway, making the recent 18% intraday sell-off appear largely overdone, the firm says.
Titan Partners
NULL -> Buy
initiated
$7
2026-02-13
Reason
Titan Partners
Price Target
$7
2026-02-13
initiated
NULL -> Buy
Reason
Titan Partners initiated coverage of Altimmune with a Buy rating and $7 price target. The Phase II data suggest pemvidutide has a "competitive profile," the analyst tells investors in a research note. Titan views Altimmune as a high risk/high reward stock with potential to exceed the price target if pemvidutide shows strong Phase III data.
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Valuation Metrics

The current forward P/E ratio for Altimmune Inc (ALT.O) is -3.14, compared to its 5-year average forward P/E of -5.64. For a more detailed relative valuation and DCF analysis to assess Altimmune Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.64
Current PE
-3.14
Overvalued PE
-2.63
Undervalued PE
-8.66

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.68
Current EV/EBITDA
-1.42
Overvalued EV/EBITDA
-0.86
Undervalued EV/EBITDA
-4.51

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
30324.32
Current PS
118142.51
Overvalued PS
85707.28
Undervalued PS
-25058.64

Financials

AI Analysis
Annual
Quarterly

Whales Holding ALT

T
Tang Capital Management, LLC
Holding
ALT
+2.62%
3M Return

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Frequently Asked Questions

What is Altimmune Inc (ALT) stock price today?

The current price of ALT is 3.655 USD — it has decreased -3.82

What is Altimmune Inc (ALT)'s business?

Altimmune, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing next-generation peptide-based therapeutics. It is developing pemvidutide, a GLP-1/glucagon dual receptor agonist for the treatment of obesity, metabolic dysfunction-associated steatohepatitis (MASH) and other indications. Activation of the GLP-1 and glucagon receptors is believed to mimic the complementary effects of diet and exercise on weight loss, with GLP-1 suppressing appetite and glucagon increasing energy expenditure. Glucagon is also recognized as having direct effects on hepatic fat metabolism, to rapid reductions in levels of liver fat and serum lipids. The Company has completed the MOMENTUM Phase II obesity trial and is being studied in the IMPACT Phase IIb MASH trial. The Company also develops and commercializes surfactant-functionalized (EuPort domain) incretin-based peptide therapeutics, including (GLP-1-glucagon)/oxyntomodulin, and variants.

What is the price predicton of ALT Stock?

Wall Street analysts forecast ALT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ALT is16.00 USD with a low forecast of 12.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Altimmune Inc (ALT)'s revenue for the last quarter?

Altimmune Inc revenue for the last quarter amounts to 26.00K USD, increased 420.00

What is Altimmune Inc (ALT)'s earnings per share (EPS) for the last quarter?

Altimmune Inc. EPS for the last quarter amounts to -0.26 USD, decreased -21.21

How many employees does Altimmune Inc (ALT). have?

Altimmune Inc (ALT) has 57 emplpoyees as of March 12 2026.

What is Altimmune Inc (ALT) market cap?

Today ALT has the market capitalization of 494.27M USD.