Aligos Therapeutics Presents Positive HBV and Weight Loss Data at HEP-DART 2025
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 11 2025
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Source: Newsfilter
- HBV Treatment Potential: Aligos showcased positive data from a 96-week study of 300mg pevifoscorvir sodium monotherapy at HEP-DART 2025, indicating its potential as a first-line therapy for chronic hepatitis B, thereby reinforcing the company's leadership in the liver disease sector.
- Significant Weight Loss Effects: New data reveals that the combination of ALG-055009 with semaglutide can achieve up to 40% weight loss, significantly enhancing efficacy compared to monotherapy, highlighting its potential value in treating obesity and metabolic diseases.
- Clinical Research Advancements: In diet-induced obese mice, the combination of ALG-055009 with incretin receptor agonists demonstrated synergistic effects, further validating its importance in future combination therapies and potentially increasing the company's market share in the cardiometabolic space.
- Commitment to Continuous Innovation: Aligos has made promising advancements in early-stage HBV and HDV research, showcasing its ongoing commitment to developing next-generation therapies in liver and viral diseases, which enhances investor confidence in its future growth potential.
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Analyst Views on ALGS
Wall Street analysts forecast ALGS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ALGS is 81.67 USD with a low forecast of 20.00 USD and a high forecast of 175.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
3 Analyst Rating
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 8.590
Low
20.00
Averages
81.67
High
175.00
Current: 8.590
Low
20.00
Averages
81.67
High
175.00
About ALGS
Aligos Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing novel therapeutics to address unmet medical needs in liver diseases and viral infections, including in the areas of chronic hepatitis B virus (HBV) infection, metabolic dysfunction-associated steatohepatitis (MASH), and coronavirus infections such as, SARS-Co-V2, SARS-CoV, MERS-CoV, and other related infections. Its pipeline of drug candidates includes ALG-000184 for chronic HBV infection, ALG-055009 for MASH, ALG-097558 for coronavirus infections, and a portfolio of preclinical programs. ALG-000184 is a potential Capsid Assembly Modulator (CAM-E) for chronic HBV infection with enhanced pharmacologic properties. In the area of chronic HBV infection, its advanced drug candidate, ALG-000184, helps in disrupting the HBV lifecycle with viral suppression as well as reductions in viral antigens. Its ALG-055009 is an oral, small-molecule thyroid receptor beta agonist (THR-β) for the treatment of MASH.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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