Actinium Presents ATNM-400 Breast Cancer Data, Demonstrating Strong Anti-Tumor Activity
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 12 2025
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Source: PRnewswire
- Strong Anti-Tumor Activity: ATNM-400 demonstrated significant tumor growth inhibition across various breast cancer models, particularly in hormone receptor-positive and triple-negative cases, with all treatment regimens well tolerated and no significant body weight changes observed, indicating its potential clinical value.
- Effectiveness Against Resistant Tumors: The drug induced irreversible DNA damage in standard treatment-resistant breast cancer models, showcasing its unique advantage in addressing resistant tumors and potentially offering new treatment options for patients.
- Broad Applicability: ATNM-400 not only shows strong efficacy in breast cancer but also exhibits promising anti-tumor activity in prostate cancer and non-small cell lung cancer, supporting its potential as a targeted radiotherapy for multiple solid tumors.
- Market Demand Alignment: With an estimated increase to 250,000 women living with metastatic breast cancer by 2030, the development of ATNM-400 aligns perfectly with this growing market need, potentially providing new hope for patients with hard-to-treat breast cancer.
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Analyst Views on ATNM
Wall Street analysts forecast ATNM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ATNM is 6.00 USD with a low forecast of 4.00 USD and a high forecast of 9.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
3 Analyst Rating
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 1.220
Low
4.00
Averages
6.00
High
9.00
Current: 1.220
Low
4.00
Averages
6.00
High
9.00
About ATNM
Actinium Pharmaceuticals, Inc. specializes in the development of targeted radiotherapies. The Company is advancing its lead product candidate Actimab-A, a CD33 targeting therapeutic, as potential backbone therapy in acute myeloid leukemia (AML) and other myeloid malignancies leveraging the mutation agnostic alpha-emitter radioisotope payload Actinium-225 (Ac-225). The Company is engaged with the National Cancer Institute (NCI) under the Cooperative Research and Development Agreement (CRADA) for development of Actimab-A in AML and other myeloid malignancies. ATNM-400 is the Company's novel non-PSMA targeting Ac-225 radiotherapy for prostate cancer. Iomab-ACT, its conditioning candidate, is being developed to improve patient access and outcomes for potentially curative cell and gene therapies. Its Iomab-B program is an induction and conditioning agent prior to bone marrow transplant in patients with r/r AML, which it is seeking a potential strategic partner for the United States.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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