AbbVie’s First ADC DECNUPAZ Approved for BPDCN Treatment
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1 day ago
0mins
Source: PRnewswire
- FDA Approval: AbbVie's DECNUPAZ (pivekimab sunirine-pvzy) has received FDA approval as the first antibody-drug conjugate for treating adult patients with BPDCN, marking a significant advancement in blood cancer therapy.
- Clinical Trial Results: In the Phase 1/2 CADENZA trial, 69.7% of 33 newly diagnosed BPDCN patients achieved a composite complete response, with a median duration of response lasting 9.7 months, demonstrating the drug's efficacy and tolerability.
- Expanded Treatment Options: DECNUPAZ provides a new treatment alternative for BPDCN patients, particularly those with relapsed or refractory disease, addressing a critical gap in therapeutic options and holding substantial clinical significance.
- Safety Warnings: The use of DECNUPAZ is associated with serious side effects, including hepatotoxicity and infusion-related reactions, prompting AbbVie to emphasize the need for close monitoring of liver function during treatment to ensure patient safety.
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Analyst Views on ABBV
Wall Street analysts forecast ABBV stock price to rise
18 Analyst Rating
12 Buy
6 Hold
0 Sell
Moderate Buy
Current: 218.630
Low
223.00
Averages
252.00
High
289.00
Current: 218.630
Low
223.00
Averages
252.00
High
289.00
About ABBV
AbbVie Inc. is a global, diversified, research-based biopharmaceutical company. It is engaged in research and development, manufacturing, commercialization and sale of medicines and therapies. Its product portfolio includes Immunology, Oncology, Aesthetics, Neuroscience, Eye Care and Other Key Products. Immunology products include rheumatology, dermatology and gastroenterology. Oncology products include Imbruvica, Venclexta/Venclyxto, Elahere and Epkinly. The aesthetics portfolio consists of facial injectables, plastics and regenerative medicine, body contouring, and skincare products. Its Neuroscience products include Botox Therapeutic, Vraylar, Duopa and Duodopa, Ubrelvy, and Qulipta. Duodopa is a levodopa-carbidopa intestinal gel for the treatment of Parkinson's disease. Eye care products include Ozurdex, Lumigan/Ganfort, Alphagan/Combigan, Restasis, and other eye care. Other key products include Mavyret/Maviret, Creon, and Linzess/Constella.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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