GSK's Exdensur Approved for Severe Asthma, Boosting Stock
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 23 2025
0mins
Should l Buy GSK?
Source: NASDAQ.COM
GSK's stock rose 3.00% and reached a 52-week high following the approval of Exdensur by the European Commission for severe asthma.
The approval of GSK's Exdensur (depemokimab) is a significant advancement in the respiratory disease sector, based on successful phase 3 trial results that demonstrated a 58% and 48% reduction in asthma attack rates. This approval is expected to address the substantial unmet needs of over 42 million asthma patients in Europe, potentially driving future growth for GSK.
The positive market reaction reflects investor confidence in GSK's ability to deliver innovative treatments, which may enhance its competitive position in the pharmaceutical market.
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Analyst Views on GSK
Wall Street analysts forecast GSK stock price to fall
6 Analyst Rating
1 Buy
2 Hold
3 Sell
Moderate Sell
Current: 55.510
Low
20.15
Averages
38.72
High
55.60
Current: 55.510
Low
20.15
Averages
38.72
High
55.60
About GSK
GSK plc is a biopharma company. The Company’s segments include Commercial Operations and Research and Development. Its portfolio and pipeline are focused on developing medicines and vaccines in four core therapeutic areas, which are the areas of human health it focuses on to prevent and treat disease: respiratory, immunology and inflammation; oncology; human immunodeficiency virus (HIV), and infectious diseases. Its specialty medicines prevent and treat diseases, from HIV to respiratory diseases, immune-mediated conditions like lupus, and cancer. Its vaccine portfolio includes over 20 vaccines to protect people from diseases and infections throughout their lives. General medicines include inhaled medicines for asthma and COPD to antibiotics. It develops and commercializes preclinical antibody-drug conjugate for Metastatic castration-resistant prostate cancer. Its portfolio also includes Efimosfermin, a fibroblast growth factor 21 (FGF21) analog therapeutic in clinical development.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Market Potential: With FDA approval, GSK is poised to lead the treatment market for cerebral folate deficiency, addressing the growing patient demand and potentially driving future revenue growth for the company.
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- Upfront and Milestone Payments: GSK will receive an upfront payment of $300 million, with an additional $100 million upon FDA approval, and $20 million upon EU and UK approval, along with up to $270 million in sales-based milestone payments, significantly enhancing GSK's cash flow.
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- Maximum Decline: The study noted a peak decline of 20% in prescriptions during the third week post-September 22, suggesting that Trump's comments directly influenced pregnant women's medication choices, potentially leaving thousands without necessary pain or fever treatment.
- Emergency Visit Data: The findings are based on nearly 90,000 emergency department visits by pregnant women and approximately 853,000 by non-pregnant women, highlighting how fear stemming from public statements can adversely affect health management decisions.
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See More
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- Vaccine Market Dynamics: Merck and GSK market MMR vaccines in the U.S., and with the escalating outbreak, the demand for vaccines is likely to rise significantly, potentially impacting the sales performance of both companies.
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