What Caused Alpha Tau Medical (DRTS) Shares to Surge More Than 25% in After-Hours Trading?
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 10 2025
0mins
Should l Buy DRTS?
Source: Benzinga
Stock Performance: Alpha Tau Medical Ltd. (NASDAQ: DRTS) shares surged 25.26% to $5.30 in after-hours trading following the announcement of the first patient treatment in a pilot study for recurrent glioblastoma multiforme using their Alpha DaRT alpha-radiation therapy.
Clinical Trial Announcement: The treatment was administered at The Ohio State University Center, led by a multidisciplinary team, marking a significant step in addressing the urgent need for new therapies for patients with recurrent glioblastoma.
Regulatory Milestones: The company received FDA Breakthrough Device Designation and was accepted into the FDA’s Total Product Life Cycle Advisory Program to expedite the marketing of the Alpha DaRT treatment.
Market Insights: DRTS shares have increased by 39.60% over the past year, with a market capitalization of $363.47 million, indicating strong momentum and potential for continued growth in the oncology therapeutics sector.
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Analyst Views on DRTS
Wall Street analysts forecast DRTS stock price to rise
3 Analyst Rating
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 6.550
Low
5.00
Averages
7.00
High
9.00
Current: 6.550
Low
5.00
Averages
7.00
High
9.00
About DRTS
Alpha Tau Medical Ltd is an Israel-based medical technology company that focuses on research, development and commercialization of Alpha DaRT Diffusing Alpha-emitters Radiation Therapy (Alpha DaRT) for the treatment of solid cancer. Company's technology relies on the diffusion of atoms that emit alpha particles within the tumor tissue, and enables alpha radiation to reach the the entire tumor. Precise amounts of radioactive radium-224 affixed that emit short-range alpha radiation enables to damages and kills cancer cells within a short period of time. The Company has one subsidiary Healthcare Capital Corp.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Alpha Tau Medical to Present Clinical Trial Results at DDW 2026
- Clinical Trial Results: Alpha Tau Medical announced that results from two clinical trials in Jerusalem for pancreatic cancer have been accepted for oral presentation at DDW 2026, marking the first major showcase of its Alpha DaRT technology in this field, potentially enhancing the company's reputation and market recognition in cancer treatment.
- Significant Conference Presentation: The presentation is scheduled for May 2, 2026, during the Pancreatic Cancer Diagnosis and Treatment session at DDW 2026, led by Dr. Harold Jacob from Hadassah Medical Center, which is expected to attract attention from numerous industry experts and further promote the clinical application of Alpha DaRT.
- Recognition of Technological Potential: CEO Uzi Sofer stated that this achievement reflects the growing recognition of the potential of their technology, especially given that most pancreatic cancer patients are deemed inoperable at diagnosis, with Alpha DaRT offering new treatment hope that could change patient outcomes.
- Future Research Directions: Chief Medical Officer Dr. Robert Den emphasized that these foundational studies have provided critical insights for their clinical development program, including the ongoing IMPACT pilot study actively enrolling in the U.S., demonstrating the company's commitment to advancing the commercialization of Alpha DaRT technology.
See More
Alpha Tau Medical Advances Clinical Trials for Cancer Treatments
- IMPACT Trial Overview: Alpha Tau's IMPACT trial is set to enroll up to 30 patients with newly diagnosed, inoperable pancreatic adenocarcinoma across the U.S., Canada, and Israel, with patient enrollment expected to complete by Q1 2026, aiming to evaluate the safety and effectiveness of Alpha DaRT, potentially offering new treatment options for patients.
- ReSTART Trial Focus: The ongoing ReSTART study evaluates Alpha DaRT in patients with recurrent cutaneous squamous cell carcinoma, also expected to complete enrollment by Q1 2026, particularly targeting patients ineligible for surgery or standard radiation, highlighting significant market demand for this therapy.
- FDA Certification Progress: Alpha Tau has secured Breakthrough Device Designation from the U.S. FDA for recurrent cutaneous squamous cell carcinoma and other cancers, reflecting high regulatory recognition of the therapy's potential, which may accelerate its review and development process, enhancing market competitiveness.
- Market Sentiment Analysis: DRTS stock has maintained a 'bullish' sentiment on Stocktwits over the past 24 hours, with a year-to-date gain of nearly 38%, indicating strong investor expectations for upcoming clinical trial data that could further drive stock price appreciation.
See More
Alpha Tau Medical Reports FY GAAP EPS of -$0.42
- Earnings Report: Alpha Tau Medical reported a FY GAAP EPS of -$0.42, indicating challenges in profitability that may negatively impact investor confidence and stock performance.
- Cash Position: As of December 31, 2025, the company had cash and cash equivalents, short-term deposits, and restricted deposits totaling $76.9 million, an increase from $62.9 million at December 31, 2024, suggesting improved liquidity management.
- Future Outlook: Updates on pancreatic cancer and GBM indicate that Alpha Tau Medical is positioning itself for a strong and catalyst-rich 2026, potentially attracting more investor interest.
- Market Reaction: Despite the reported losses, the company's efforts in R&D and market expansion may yield positive market reactions in the future, particularly with new therapies and clinical trial advancements.
See More
Japan Approves New Head and Neck Cancer Treatment Device
- Innovative Treatment Device: HekaBio K.K. announces that its developed Alpha DaRT (Diffusing Alpha Radiation Therapy) device has received official approval in Japan, becoming the first country outside Israel to approve it, marking Japan's leadership in tumor treatment.
- Significant Market Potential: Designed for patients with unresectable locally advanced or recurrent head and neck cancer, this device offers a new therapeutic option, expected to significantly improve treatment outcomes and fill the gap left by conventional therapies.
- Clinical Trial Results: Clinical trials demonstrate that Alpha DaRT effectively disrupts tumor cell DNA, leading to cell death, with high safety and efficacy, providing crucial evidence for future clinical applications and potentially transforming head and neck cancer treatment.
- Strategic Collaboration and Development: HekaBio is closely collaborating with Japanese medical professionals to conduct post-marketing studies and explore reimbursement options for Alpha DaRT, indicating its long-term growth potential in the Japanese market and commitment to patients.
See More
Biotech Stocks Surge: Coherus Up 9.09% in After-Hours Trading
- Coherus Performance: Coherus Oncology, Inc. (CHRS) rose 9.09% in after-hours trading, closing at $1.73 with a $0.14 gain, indicating strong investor confidence in its future prospects.
- Sensei Biotech Surge: Sensei Biotherapeutics, Inc. (SNSE) surged 10.06% after hours, finishing at $12.47 with a $1.14 increase, reflecting positive market expectations for its products.
- uniQure Significant Jump: uniQure N.V. (QURE) posted a 9.96% rise in after-hours trading, closing at $24.95 with a $2.26 gain, suggesting investor optimism regarding its R&D progress.
- IO Biotech Strategic Exploration: Although IO Biotech, Inc. (IOBT) had no fresh news on Thursday, its stock still gained 4.19%, closing at $0.50, indicating market interest in its exploration of strategic alternatives, including potential mergers or asset sales.
See More
TG Therapeutics Reports $616 Million Revenue for FY 2025, Shares Surge 11.6%
- Strong Financial Performance: TG Therapeutics reported preliminary total global revenue of approximately $616 million for FY 2025, with Q4 U.S. net product revenue for BRIUMVI at about $182 million, indicating robust market performance that is expected to boost shareholder confidence.
- Significant Stock Surge: Following the earnings report, TG Therapeutics shares jumped 11.6% to $31.10 on Wednesday, reflecting investor optimism about the company's growth potential, which may attract more capital inflow.
- Positive Market Reaction: Despite a broader market decline with the Nasdaq Composite falling over 200 points, TG Therapeutics' strong financial data allowed it to stand out among numerous stocks, showcasing its competitiveness in the biopharmaceutical sector.
- Optimistic Future Outlook: Although the financial figures are unaudited, the preliminary results suggest that the company is poised for continued growth, particularly in the marketing of its BRIUMVI product, which could further enhance its market share.
See More
Alpha Tau Medical to Present Clinical Trial Results at DDW 2026
- Clinical Trial Results: Alpha Tau Medical announced that results from two clinical trials in Jerusalem for pancreatic cancer have been accepted for oral presentation at DDW 2026, marking the first major showcase of its Alpha DaRT technology in this field, potentially enhancing the company's reputation and market recognition in cancer treatment.
- Significant Conference Presentation: The presentation is scheduled for May 2, 2026, during the Pancreatic Cancer Diagnosis and Treatment session at DDW 2026, led by Dr. Harold Jacob from Hadassah Medical Center, which is expected to attract attention from numerous industry experts and further promote the clinical application of Alpha DaRT.
- Recognition of Technological Potential: CEO Uzi Sofer stated that this achievement reflects the growing recognition of the potential of their technology, especially given that most pancreatic cancer patients are deemed inoperable at diagnosis, with Alpha DaRT offering new treatment hope that could change patient outcomes.
- Future Research Directions: Chief Medical Officer Dr. Robert Den emphasized that these foundational studies have provided critical insights for their clinical development program, including the ongoing IMPACT pilot study actively enrolling in the U.S., demonstrating the company's commitment to advancing the commercialization of Alpha DaRT technology.
See More
Alpha Tau Medical Advances Clinical Trials for Cancer Treatments
- IMPACT Trial Overview: Alpha Tau's IMPACT trial is set to enroll up to 30 patients with newly diagnosed, inoperable pancreatic adenocarcinoma across the U.S., Canada, and Israel, with patient enrollment expected to complete by Q1 2026, aiming to evaluate the safety and effectiveness of Alpha DaRT, potentially offering new treatment options for patients.
- ReSTART Trial Focus: The ongoing ReSTART study evaluates Alpha DaRT in patients with recurrent cutaneous squamous cell carcinoma, also expected to complete enrollment by Q1 2026, particularly targeting patients ineligible for surgery or standard radiation, highlighting significant market demand for this therapy.
- FDA Certification Progress: Alpha Tau has secured Breakthrough Device Designation from the U.S. FDA for recurrent cutaneous squamous cell carcinoma and other cancers, reflecting high regulatory recognition of the therapy's potential, which may accelerate its review and development process, enhancing market competitiveness.
- Market Sentiment Analysis: DRTS stock has maintained a 'bullish' sentiment on Stocktwits over the past 24 hours, with a year-to-date gain of nearly 38%, indicating strong investor expectations for upcoming clinical trial data that could further drive stock price appreciation.
See More
Alpha Tau Medical Reports FY GAAP EPS of -$0.42
- Earnings Report: Alpha Tau Medical reported a FY GAAP EPS of -$0.42, indicating challenges in profitability that may negatively impact investor confidence and stock performance.
- Cash Position: As of December 31, 2025, the company had cash and cash equivalents, short-term deposits, and restricted deposits totaling $76.9 million, an increase from $62.9 million at December 31, 2024, suggesting improved liquidity management.
- Future Outlook: Updates on pancreatic cancer and GBM indicate that Alpha Tau Medical is positioning itself for a strong and catalyst-rich 2026, potentially attracting more investor interest.
- Market Reaction: Despite the reported losses, the company's efforts in R&D and market expansion may yield positive market reactions in the future, particularly with new therapies and clinical trial advancements.
See More
Japan Approves New Head and Neck Cancer Treatment Device
- Innovative Treatment Device: HekaBio K.K. announces that its developed Alpha DaRT (Diffusing Alpha Radiation Therapy) device has received official approval in Japan, becoming the first country outside Israel to approve it, marking Japan's leadership in tumor treatment.
- Significant Market Potential: Designed for patients with unresectable locally advanced or recurrent head and neck cancer, this device offers a new therapeutic option, expected to significantly improve treatment outcomes and fill the gap left by conventional therapies.
- Clinical Trial Results: Clinical trials demonstrate that Alpha DaRT effectively disrupts tumor cell DNA, leading to cell death, with high safety and efficacy, providing crucial evidence for future clinical applications and potentially transforming head and neck cancer treatment.
- Strategic Collaboration and Development: HekaBio is closely collaborating with Japanese medical professionals to conduct post-marketing studies and explore reimbursement options for Alpha DaRT, indicating its long-term growth potential in the Japanese market and commitment to patients.
See More
Biotech Stocks Surge: Coherus Up 9.09% in After-Hours Trading
- Coherus Performance: Coherus Oncology, Inc. (CHRS) rose 9.09% in after-hours trading, closing at $1.73 with a $0.14 gain, indicating strong investor confidence in its future prospects.
- Sensei Biotech Surge: Sensei Biotherapeutics, Inc. (SNSE) surged 10.06% after hours, finishing at $12.47 with a $1.14 increase, reflecting positive market expectations for its products.
- uniQure Significant Jump: uniQure N.V. (QURE) posted a 9.96% rise in after-hours trading, closing at $24.95 with a $2.26 gain, suggesting investor optimism regarding its R&D progress.
- IO Biotech Strategic Exploration: Although IO Biotech, Inc. (IOBT) had no fresh news on Thursday, its stock still gained 4.19%, closing at $0.50, indicating market interest in its exploration of strategic alternatives, including potential mergers or asset sales.
See More
TG Therapeutics Reports $616 Million Revenue for FY 2025, Shares Surge 11.6%
- Strong Financial Performance: TG Therapeutics reported preliminary total global revenue of approximately $616 million for FY 2025, with Q4 U.S. net product revenue for BRIUMVI at about $182 million, indicating robust market performance that is expected to boost shareholder confidence.
- Significant Stock Surge: Following the earnings report, TG Therapeutics shares jumped 11.6% to $31.10 on Wednesday, reflecting investor optimism about the company's growth potential, which may attract more capital inflow.
- Positive Market Reaction: Despite a broader market decline with the Nasdaq Composite falling over 200 points, TG Therapeutics' strong financial data allowed it to stand out among numerous stocks, showcasing its competitiveness in the biopharmaceutical sector.
- Optimistic Future Outlook: Although the financial figures are unaudited, the preliminary results suggest that the company is poised for continued growth, particularly in the marketing of its BRIUMVI product, which could further enhance its market share.
See More
