Johnson & Johnson's Icotyde Approved by FDA for Plaque Psoriasis
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Mar 18 2026
0mins
Should l Buy JNJ?
Source: seekingalpha
- FDA Approval: Johnson & Johnson announced that its once-daily pill Icotyde, developed with Protagonist Therapeutics, has received FDA approval as a treatment for moderate-to-severe plaque psoriasis, marking a significant breakthrough in treatment options.
- Successful Clinical Trials: Icotyde demonstrated strong efficacy in J&J's pivotal ICONIC clinical development program, achieving primary efficacy endpoints with a favorable safety profile across four Phase 3 studies involving 2,500 patients, enhancing its competitive position in the market.
- Significant Market Need: Plaque psoriasis affects nearly 8 million Americans and 125 million people globally, with about 25% suffering from moderate-to-severe cases, and Icotyde offers an innovative treatment option for patients currently relying on topical therapies, addressing a critical market demand.
- Milestone Payments and Royalties: Protagonist Therapeutics announced that the FDA approval triggers a $50 million milestone payment and will receive 6%-10% royalties on Icotyde sales, along with potential future milestone payments of up to $580 million, significantly improving its financial outlook.
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Analyst Views on JNJ
Wall Street analysts forecast JNJ stock price to fall
20 Analyst Rating
13 Buy
7 Hold
0 Sell
Moderate Buy
Current: 240.450
Low
190.00
Averages
218.50
High
240.00
Current: 240.450
Low
190.00
Averages
218.50
High
240.00
About JNJ
Johnson & Johnson and its subsidiaries are engaged in the research and development, manufacture, and sale of a range of products in the healthcare field. The Company’s segments include Innovative Medicine and MedTech. The Innovative Medicine segment is focused on various therapeutic areas, including immunology, infectious diseases, neuroscience, oncology, pulmonary hypertension, cardiovascular and metabolism. Its products include REMICADE (infliximab), SIMPONI (golimumab), SIMPONI ARIA (golimumab), STELARA (ustekinumab), TREMFYA (guselkumab), EDURANT (rilpivirine), and INVEGA SUSTENNA/XEPLION (paliperidone palmitate). The MedTech segment includes a portfolio of products used in cardiovascular, orthopedics, surgery, and vision categories. The Cardiovascular portfolio includes electrophysiology products to treat heart rhythm disorders and circulatory restoration products (Shockwave) for the treatment of calcified coronary artery disease (CAD) and peripheral artery disease (PAD).
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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