Alector Appoints Neil Berkley as CFO
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 12 2025
0mins
Alector announced that Neil Berkley, who has served as Alector's CBO since March 2024, and CBO and Interim CFO since June 2025, has been appointed CFO, effective December 10, 2025. Berkley will continue to serve as CBO.
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Analyst Views on ALEC
Wall Street analysts forecast ALEC stock price to rise
8 Analyst Rating
1 Buy
5 Hold
2 Sell
Hold
Current: 1.930
Low
0.90
Averages
2.10
High
5.00
Current: 1.930
Low
0.90
Averages
2.10
High
5.00
About ALEC
Alector, Inc. is a clinical-stage biotechnology company. The Company is focused on developing therapies to counteract the devastating progression of neurodegenerative diseases. It also develops alector brain carrier (ABC), a proprietary blood-brain barrier platform, which is applied to its next-generation product candidates and research pipeline. Its research and drug discovery platform leverages human genetic datasets, advanced tools in bioinformatics and imaging, and insights in neurodegeneration. Its clinical development portfolio includes latozinemab (AL001) and AL101/GSK4527226, while its preclinical and research pipeline candidates include ADP037-ABC, ADP050-ABC, ADP056, and ADP063-ABC/ADP064-ABC. Its first product candidate, latozinemab, is a human recombinant monoclonal antibody that increases the levels of progranulin (PGRN) in the brains of FTD-GRN patients. The AL101/GSK4527226, is a human recombinant monoclonal antibody designed to elevate PGRN levels in the brain.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Commitment to Future Development: Despite the trial's halt, CEO Arnon Rosenthal emphasized Alector's commitment to advancing its broader pipeline targeting neurodegenerative diseases, including multiple wholly owned candidates enabled by their ABC platform, showcasing confidence in future research endeavors.
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See More
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- Resource Reallocation: Following discussions with Alector executives, the company decided to prioritize resources towards the ABC platform to support the delivery of brain-targeting therapies, reflecting its commitment to this technology.
- Positive Market Reaction: Alector's shares rose after the upgrade, indicating investor confidence in its BBB-crossing technology, although the current market does not fully reflect the value of the ABC platform.
- Future Outlook: Analysts noted that the potential of Alector's ABC platform in neurodegenerative drug development is not yet fully recognized by the market, suggesting significant business growth opportunities ahead.
See More
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- Workforce Reduction and Project Adjustments: The failure of the INFRONT-3 clinical trial forced Alector to cut nearly 49% of its workforce and halt the open-label extension of INFRONT-3 and the continuation study for latozinemab, which, while impacting operations in the short term, allows for a focused approach moving forward.
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See More
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