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ALEC Overview

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ET
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ET
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Intellectia

Loading chart...

High
2.645
Open
2.430
VWAP
2.52
Vol
1.15M
Mkt Cap
241.69M
Low
2.410
Amount
2.90M
EV/EBITDA(TTM)
--
Total Shares
110.36M
EV
-4.64M
EV/OCF(TTM)
--
P/S(TTM)
10.72
Alector, Inc. is a clinical-stage biotechnology company. The Company is focused on developing therapies to counteract the devastating progression of neurodegenerative diseases. It also develops alector brain carrier (ABC), a proprietary blood-brain barrier platform, which is applied to its next-generation product candidates and research pipeline. Its research and drug discovery platform leverages human genetic datasets, advanced tools in bioinformatics and imaging, and insights in neurodegeneration. Its clinical development portfolio includes latozinemab (AL001) and AL101/GSK4527226, while its preclinical and research pipeline candidates include ADP037-ABC, ADP050-ABC, ADP056, and ADP063-ABC/ADP064-ABC. Its first product candidate, latozinemab, is a human recombinant monoclonal antibody that increases the levels of progranulin (PGRN) in the brains of FTD-GRN patients. The AL101/GSK4527226, is a human recombinant monoclonal antibody designed to elevate PGRN levels in the brain.
Show More

Events Timeline

(ET)
2026-02-25
16:50:00
Alector Reports Q4 Revenue of $6.2M, Beating Consensus
select
2025-12-12 (ET)
2025-12-12
16:10:00
Alector Appoints Neil Berkley as CFO
select
2025-11-06 (ET)
2025-11-06
18:22:40
Alector announces Q3 earnings per share of 34 cents, falling short of the expected 41 cents.
select

News

CNBC
6.0
13:03 PMCNBC
Latest Wall Street Rating Updates
  • BofA Downgrades Qualcomm: Bank of America has downgraded Qualcomm from neutral to underperform with a price target of $145, citing lukewarm projected sales and EPS growth of only 2% and 1% CAGR from 2025 to 2028, significantly lagging the semiconductor sector's expected 17% growth.
  • Deutsche Bank Upgrades Teladoc: Deutsche Bank upgraded Teladoc from hold to buy, highlighting an attractive risk/reward profile due to compelling valuation and a deliverable strategy for its BetterHelp business, indicating a strong potential for future growth.
  • TD Cowen Upgrades Rivian: TD Cowen upgraded Rivian from hold to buy, projecting full-scale demand for its R2 model to reach between 212,000 and 335,000 units, suggesting significant upside potential against 2027 consensus estimates.
  • Morgan Stanley Reiterates Microsoft Overweight: Morgan Stanley reiterated its overweight rating on Microsoft, emphasizing the readiness of its Office product suite for the upcoming Agentic AI offerings, with general availability expected on May 1, 2026, priced at $99 per user per month.
Benzinga
4.0
13:02 PMBenzinga
Wall Street Analysts Adjust Ratings
  • Analyst Rating Changes: Top Wall Street analysts have adjusted their ratings on several companies, reflecting varying market perspectives that could influence investor decisions and market trends.
  • Upgrades and Downgrades: The rating changes include upgrades and downgrades for certain stocks, prompting investors to pay attention to these shifts to assess potential investment opportunities and risks.
  • Market Reaction Expectations: Analysts' rating adjustments may lead to short-term volatility in the affected stocks, necessitating investors to closely monitor market dynamics to seize investment opportunities.
  • Information Source: A complete view of all analyst rating changes can be found on Benzinga's analyst ratings page, providing crucial insights for investor decision-making.
Yahoo Finance
8.5
03-04Yahoo Finance
Alector Showcases ABC Brain-Delivery Platform Progress
  • ABC Platform Advantage: Alector's ABC platform utilizes the side epitope of the transferrin receptor (TfR) to achieve over a 12-fold increase in cerebrospinal fluid (CSF) levels in non-human primates, significantly enhancing drug uptake in the brain while reducing Fc-mediated safety risks, showcasing its potential in treating neurodegenerative diseases.
  • AL137 Clinical Progress: AL137, an anti-amyloid antibody enabled by ABC technology, achieved approximately 30-fold higher brain tissue uptake in non-human primates and demonstrated good tolerability at a 3 mg/kg therapeutic dose, with an IND filing expected by year-end and plans for rapid initiation of first-in-human trials.
  • Innovation in AL050: Alector's AL050 program features an engineered glucocerebrosidase (GCase) with 50 times the activity of wild-type, showing significant increases in brain enzymatic activity in non-human primates, indicating promising applications for treating GBA-associated Parkinson's disease and Lewy body dementia.
  • siRNA Delivery Capability: Alector's siRNA program leverages ABC technology for peripheral dosing, with non-human primate studies demonstrating up to 70% tau mRNA knockdown across brain regions and no adverse events observed, highlighting its broad application potential in neurodegenerative disease treatment.
seekingalpha
9.5
02-26seekingalpha
Alector Reports Q4 Earnings Amidst Challenges
  • Earnings Report: Alector reported a Q4 GAAP EPS of -$0.34 and revenue of $6.2 million, indicating financial strain amidst ongoing challenges that may undermine investor confidence.
  • Drug Development Setback: The failure of Latozinemab has led to a decline in Alector's stock price, reflecting market concerns over its drug pipeline and potentially complicating future financing efforts.
  • Executive Appointment: Alector appointed Neil Berkley as CFO, aiming to enhance financial management capabilities through new leadership to navigate current market challenges and strategic adjustments.
  • Investor Focus: Alector's presentation at the BofA Securities CNS Therapeutics Virtual Conference garnered attention, with investors looking forward to updates from its Phase 2 clinical trials to restore market confidence.
PRnewswire
9.0
01-29PRnewswire
Alector's Phase 3 Trial Results Fail to Meet Expectations
  • Trial Results: Alector's Phase 3 INFRONT-3 trial evaluating latozinemab showed that while the biomarker response met expectations, the clinical co-primary endpoint was not achieved, leading to investor disappointment.
  • Participant Demographics: The trial enrolled 119 patients, including 103 symptomatic FTD-GRN individuals and 16 at-risk carriers, with a mean age of 62.1 years, indicating the drug's potential application in a specific demographic.
  • Market Reaction: Following the mixed trial results, analysts downgraded Alector's stock, reflecting market concerns about its biotech operations, which may impact the company's future financing capabilities.
  • Legal Investigation: Levi & Korsinsky, LLP is investigating Alector, highlighting investor concerns regarding the company's operational performance, which could lead to further legal actions.
Globenewswire
5.0
2025-12-12Globenewswire
Alector Appoints Neil Berkley as CFO, Strengthening Leadership Amid Strategic Growth
  • Leadership Transition: Alector announced Neil Berkley's official appointment as CFO effective December 10, 2025, while he continues as CBO, reflecting the company's high regard for his leadership and strategic insight.
  • Extensive Experience: With over 20 years in the biotech industry, Berkley has held significant roles in large pharmaceutical and biotech firms, providing Alector with deep support in finance and operations.
  • Strategic Priorities: Since joining Alector in 2024, Berkley has played a key role in advancing the company's strategic priorities, strengthening partnerships, and supporting value creation, ensuring robust progress during this critical growth phase.
  • Integration of Science and Business: Berkley expressed his commitment to supporting the company's scientific and corporate priorities in neurodegenerative diseases, particularly in advancing promising pipeline products and the development of the ABC platform, aimed at improving patient outcomes and reducing costs.
Wall Street analysts forecast ALEC stock price to rise
8 Analyst Rating
Wall Street analysts forecast ALEC stock price to rise
1 Buy
5 Hold
2 Sell
Hold
Current: 0.000
sliders
Low
0.90
Averages
2.10
High
5.00
Current: 0.000
sliders
Low
0.90
Averages
2.10
High
5.00
BTIG
Neutral -> Buy
upgrade
$6
AI Analysis
2026-03-10
New
Reason
BTIG
Price Target
$6
AI Analysis
2026-03-10
New
upgrade
Neutral -> Buy
Reason
BTIG upgraded Alector to Buy from Neutral with a $6 price target.
BTIG
Thomas Shrader
Neutral -> Buy
upgrade
$6
2026-03-10
New
Reason
BTIG
Thomas Shrader
Price Target
$6
2026-03-10
New
upgrade
Neutral -> Buy
Reason
BTIG analyst Thomas Shrader upgraded Alector to Buy from Neutral with a $6 price target. The upgrade reflects the company's shift in focus to the development of novel therapeutics equipped with BBB-shuttle domains, the analyst tells investors in a research note. The firm believes the shift removes uncertainty after the frontotemporal dementia trial failure. Alector going forward will become a "major player "in the neurodegeneration space with expertise in both protein engineering and the molecular mechanisms of neurodegeneration, contends BTIG.
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Valuation Metrics

The current forward P/E ratio for Alector Inc (ALEC.O) is -0.96, compared to its 5-year average forward P/E of -4.79. For a more detailed relative valuation and DCF analysis to assess Alector Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.79
Current PE
-0.96
Overvalued PE
5.84
Undervalued PE
-15.41

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.20
Current EV/EBITDA
0.78
Overvalued EV/EBITDA
8.11
Undervalued EV/EBITDA
-8.50

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
15.82
Current PS
87.80
Overvalued PS
37.97
Undervalued PS
-6.34

Financials

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Whales Holding ALEC

K
Kynam Capital Management, LP
Holding
ALEC
+6.36%
3M Return
T
TCG Crossover Management, LLC
Holding
ALEC
-1.28%
3M Return

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Frequently Asked Questions

What is Alector Inc (ALEC) stock price today?

The current price of ALEC is 2.51 USD — it has increased 14.61

What is Alector Inc (ALEC)'s business?

Alector, Inc. is a clinical-stage biotechnology company. The Company is focused on developing therapies to counteract the devastating progression of neurodegenerative diseases. It also develops alector brain carrier (ABC), a proprietary blood-brain barrier platform, which is applied to its next-generation product candidates and research pipeline. Its research and drug discovery platform leverages human genetic datasets, advanced tools in bioinformatics and imaging, and insights in neurodegeneration. Its clinical development portfolio includes latozinemab (AL001) and AL101/GSK4527226, while its preclinical and research pipeline candidates include ADP037-ABC, ADP050-ABC, ADP056, and ADP063-ABC/ADP064-ABC. Its first product candidate, latozinemab, is a human recombinant monoclonal antibody that increases the levels of progranulin (PGRN) in the brains of FTD-GRN patients. The AL101/GSK4527226, is a human recombinant monoclonal antibody designed to elevate PGRN levels in the brain.

What is the price predicton of ALEC Stock?

Wall Street analysts forecast ALEC stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ALEC is2.10 USD with a low forecast of 0.90 USD and a high forecast of 5.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Alector Inc (ALEC)'s revenue for the last quarter?

Alector Inc revenue for the last quarter amounts to 6.24M USD, decreased -88.50

What is Alector Inc (ALEC)'s earnings per share (EPS) for the last quarter?

Alector Inc. EPS for the last quarter amounts to -0.34 USD, increased 1600.00

How many employees does Alector Inc (ALEC). have?

Alector Inc (ALEC) has 103 emplpoyees as of March 10 2026.

What is Alector Inc (ALEC) market cap?

Today ALEC has the market capitalization of 241.69M USD.