SYRE Technical Analysis & Stock Price Forecast

Technical Sentiment

Overall Consensus

Sell

Buy

Technical Analysis Consensus

Sell

Buy

Moving Average Consensus

Sell

Buy

Spyre Therapeutics Inc (SYRE) Moving Averages Convergence Divergence (MACD) indicator is 2.904, suggesting SYRE is Strong Buy.

Spyre Therapeutics Inc (SYRE) 20-Day simple moving average is 72.423, while Spyre Therapeutics Inc (SYRE) share price is $73.85, making it Buy.

Spyre Therapeutics Inc (SYRE) 60-Day simple moving average is 57.616, while Spyre Therapeutics Inc (SYRE) share price is $73.85, making it Buy.

Technical Analysis for SYRE

Technical Sentiment Analysis for Spyre Therapeutics Inc (SYRE) As of 2026-05-21, Spyre Therapeutics Inc (SYRE) is exhibiting a Strong Buy technical sentiment. Our proprietary analysis, which aggregates 11 technical signals, shows that 11 indicators are flashing buy, while 0 are indicating sell.

Momentum Indicators: RSI, MACD & Overbought/Oversold Status Currently, the Relative Strength Index (RSI) for SYRE stands at 58.341, which suggests a Neutral condition. Meanwhile, the MACD (12, 26) indicator is at 2.904, providing a Buy signal for short-term momentum. Other oscillators like the Stochastic Oscillator at 44.309 and the Commodity Channel Index (CCI) at 19.797 further confirm a 1.153 outlook for the stock.

Support, Resistance & Moving Averages From a structural perspective, SYRE is trading above its 60-day moving average of $57.616 and above its 200-day long-term moving average of $35.157. Key price levels to watch include the immediate resistance at $80.061 and strong support at $65.931. A break above $80.061 could signal a bull continuation, while falling below $65.931 may test the next Fibonacci floor at $58.236.

Spyre Therapeutics Inc (SYRE) Support & Resistance Level

Name	S3	S2	S1	Pivot Points	R1	R2	R3
Classic	51.801	58.236	65.931	72.366	80.061	86.496	94.191
Fibonacci	58.236	63.633	66.968	72.366	77.763	81.098	86.496

Spyre Therapeutics Inc (SYRE) Technical Indicators

2026-05-21

Name	Value
RSI_14	58.341
STOCHk_14_3_3	44.309
STOCHd_14_3_3	36.484
CCI_20	19.797
AO_5_34	2.806
MOM_10	1.153
MACD_12_26_9	2.904

Spyre Therapeutics Inc (SYRE) Relative Strength Index (RSI) is 58.341, creating a Neutral signal.

Spyre Therapeutics Inc (SYRE) Stochastic Oscillator is 44.309, creating a Neutral signal.

Spyre Therapeutics Inc (SYRE) Stochastic RSI is 36.484, creating a Neutral signal.

Spyre Therapeutics Inc (SYRE) Commodity Channel Index (CCI) is 19.797, creating a Neutral signal.

Spyre Therapeutics Inc (SYRE) Awesome Oscillator is 2.806, creating a Buy signal.

Spyre Therapeutics Inc (SYRE) Momentum is 1.153, creating a Buy signal.

Spyre Therapeutics Inc (SYRE) MACD is 2.904, creating a Buy signal.

Spyre Therapeutics Inc (SYRE) Moving Average

2026-05-21

Period	Simple	Signal
MA_5	71.559	Buy
MA_10	73.627	Buy
MA_20	72.423	Buy
MA_60	57.616	Buy
MA_200	35.157	Buy
MA_250	31.371	Buy

Spyre Therapeutics Inc (SYRE) 5-Day simple moving average is 71.559, while Spyre Therapeutics Inc (SYRE) share price is $73.85, making it a Buy.

Spyre Therapeutics Inc (SYRE) 10-Day simple moving average is 73.627, while Spyre Therapeutics Inc (SYRE) share price is $73.85, making it a Buy.

Spyre Therapeutics Inc (SYRE) 20-Day simple moving average is 72.423, while Spyre Therapeutics Inc (SYRE) share price is $73.85, making it a Buy.

Spyre Therapeutics Inc (SYRE) 60-Day simple moving average is 57.616, while Spyre Therapeutics Inc (SYRE) share price is $73.85, making it a Buy.

Spyre Therapeutics Inc (SYRE) 200-Day simple moving average is 35.157, while Spyre Therapeutics Inc (SYRE) share price is $73.85, making it a Buy.

Spyre Therapeutics Inc (SYRE) 250-Day simple moving average is 31.371, while Spyre Therapeutics Inc (SYRE) share price is $73.85, making it a Buy.

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Frequently Asked Questions

What is the current technical consensus for SYRE?

The overall technical consensus for Spyre Therapeutics Inc (SYRE) is currently Strong Buy. This rating is derived from a combined analysis of moving averages and oscillators, currently showing 5 buy signals and 0 sell signals.

What are the key support and resistance levels for Spyre Therapeutics Inc (SYRE) today?

Based on pivot point calculations, Spyre Therapeutics Inc (SYRE) has an immediate support level at 65.931 and a major resistance level at 80.061. Traders also monitor the pivot point at 72.366 to determine the intraday trend direction.

Is Spyre Therapeutics Inc (SYRE) overbought or oversold based on the RSI?

The Relative Strength Index (RSI) for Spyre Therapeutics Inc (SYRE) is currently 58.341. This indicates that the stock is in neutral territory (typically, a value below 30 is oversold and above 70 is overbought).

What signal is the MACD providing for Spyre Therapeutics Inc (SYRE)?

Spyre Therapeutics Inc (SYRE) Moving Averages Convergence Divergence (MACD) indicator is 2.904, suggesting SYRE is Strong Buy. This indicator helps identify potential trend reversals or momentum shifts for Spyre Therapeutics Inc.

How is Spyre Therapeutics Inc (SYRE) performing relative to its 200-day moving average?

Spyre Therapeutics Inc (SYRE) is currently trading at $73.85, which is above its 200-day simple moving average of 35.157. Trading above the 200-day MA is often used by investors to determine the long-term bullish or bearish trend.