SPRO Technical

Technical Sentiment Analysis for Spero Therapeutics Inc (SPRO) As of 2026-03-25, Spero Therapeutics Inc (SPRO) is exhibiting a Strong Buy technical sentiment. Our proprietary analysis, which aggregates 11 technical signals, shows that 8 indicators are flashing buy, while 3 are indicating sell.

Momentum Indicators: RSI, MACD & Overbought/Oversold Status Currently, the Relative Strength Index (RSI) for SPRO stands at 47.808, which suggests a Neutral condition. Meanwhile, the MACD (12, 26) indicator is at 0.0214, providing a Buy signal for short-term momentum. Other oscillators like the Stochastic Oscillator at 30.833 and the Commodity Channel Index (CCI) at -4.981 further confirm a -0.22 outlook for the stock.

Support, Resistance & Moving Averages From a structural perspective, SPRO is trading above its 60-day moving average of $2.373 and above its 200-day long-term moving average of $2.34. Key price levels to watch include the immediate resistance at $2.685 and strong support at $2.275. A break above $2.685 could signal a bull continuation, while falling below $2.275 may test the next Fibonacci floor at $2.078.