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AXSM Should I Buy

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Intellectia

Should You Buy Axsome Therapeutics Inc (AXSM) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
159.500
1 Day change
-4.11%
52 Week Range
191.500
Analysis Updated At
2026/03/05
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Axsome Therapeutics Inc (AXSM) is not a strong buy at the moment for a beginner investor with a long-term strategy. While the company has positive growth potential and strong analyst support, the current technical indicators and financial performance suggest caution. The stock is in a downward trend, and there are no immediate catalysts or proprietary trading signals to justify a buy right now.

Technical Analysis

The MACD is negative and contracting (-2.298), indicating bearish momentum. RSI is at 20.713, which is in the neutral zone but trending towards oversold territory. The stock is trading near its S1 support level of 161.015, with no clear breakout above resistance levels. Moving averages are converging, showing indecision in the trend.

Options Data

Bullish
Open Interest Put-Call Ratio
Bearish
Option Volume Put-Call Ratio

The high option volume put-call ratio indicates bearish sentiment in the short term, with more puts being traded than calls.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
10
Buy
4

Positive Catalysts

  • and positive sentiment around the potential approval of AXS-05 for Alzheimer's disease agitation. The company's revenue grew by 65.03% YoY in Q4 2025, and its gross margin improved to 92.89%.

Neutral/Negative Catalysts

  • The stock price has been declining (-1.60% regular market change, -0.53% post-market change). Net income dropped significantly (-61.88% YoY), and EPS also declined (-63.64% YoY). Technical indicators suggest bearish momentum, and options data reflects short-term bearish sentiment.

Financial Performance

In Q4 2025, revenue increased significantly by 65.03% YoY to $195.99M, but net income dropped to -$28.56M (-61.88% YoY), and EPS fell to -0.56 (-63.64% YoY). Gross margin improved to 92.89%, indicating strong operational efficiency despite declining profitability.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are highly optimistic about AXSM, with multiple firms raising price targets (ranging from $202 to $251) and maintaining Buy or Outperform ratings. Analysts cite strong pipeline growth, operating leverage, and the potential approval of AXS-05 as key drivers for future growth.

Wall Street analysts forecast AXSM stock price to rise
15 Analyst Rating
Wall Street analysts forecast AXSM stock price to rise
14 Buy
1 Hold
0 Sell
Strong Buy
Current: 166.340
sliders
Low
153
Averages
209.54
High
260
Current: 166.340
sliders
Low
153
Averages
209.54
High
260
Morgan Stanley
Equal Weight
maintain
$204 -> $207
AI Analysis
2026-02-24
Reason
Morgan Stanley
Price Target
$204 -> $207
AI Analysis
2026-02-24
maintain
Equal Weight
Reason
Morgan Stanley raised the firm's price target on Axsome Therapeutics to $207 from $204 and keeps an Equal Weight rating on the shares. After the company reported Q4 revenues in-line with the company's January pre-announcement, the next area of focus is the AXS-05 PDUFA data on April 30 as well as continued pipeline expansion, the analyst tells investors.
UBS
Buy
maintain
$248 -> $251
2026-02-24
Reason
UBS
Price Target
$248 -> $251
2026-02-24
maintain
Buy
Reason
UBS raised the firm's price target on Axsome Therapeutics to $251 from $248 and keeps a Buy rating on the shares. Axsome is seeing significant operating leverage due to the "attractive" ADA launch, despite the meaningful salesforce expansion, the analyst tells investors in a research note.
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