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ALMS Should I Buy

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Intellectia

Should You Buy Alumis Inc (ALMS) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Buy
Latest Price
25.250
1 Day change
2.19%
52 Week Range
30.600
Analysis Updated At
2026/04/16
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Alumis Inc (ALMS) is a good buy for a beginner investor with a long-term horizon and $50,000-$100,000 available for investment. The technical indicators are bullish, insider buying is strong, and analysts maintain positive ratings with increased price targets. Despite weak financial performance, the company's lead drug has strong competitive positioning and potential catalysts in upcoming trials.

Technical Analysis

The technical indicators for ALMS are bullish. The MACD is positive and expanding, moving averages are aligned bullishly (SMA_5 > SMA_20 > SMA_200), and the stock is trading above key support levels. RSI is neutral at 69.014, indicating no overbought or oversold conditions.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
5
Buy
7

Positive Catalysts

  • Insider buying has increased significantly by 586.17% over the last month.

  • Analysts have raised price targets, with Oppenheimer increasing it to $55 and maintaining an Outperform rating.

  • The company's lead drug, envudeucitinib, has shown strong efficacy and safety in Phase 3 trials, with potential catalysts in upcoming Phase 2 and Phase 3 readouts.

Neutral/Negative Catalysts

  • Financial performance is weak, with a net income loss of -$92.93M in Q4 2025 and EPS declining by -48.85% YoY.

  • The oral psoriasis drug market is becoming increasingly competitive, as noted by H.C. Wainwright.

Financial Performance

In Q4 2025, revenue remained flat YoY at $1.93M, while net income dropped to -$92.93M (-1.93% YoY). EPS declined significantly by -48.85% YoY to -$0.89. Gross margin remained stable at 100%.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are generally bullish on ALMS. Raymond James and Oppenheimer maintain strong buy/outperform ratings, citing competitive advantages for envudeucitinib. Recent price targets have been raised to $55 (Oppenheimer) and $38 (Morgan Stanley), though H.C. Wainwright lowered its target to $25 due to increased competition.

Wall Street analysts forecast ALMS stock price to rise
7 Analyst Rating
Wall Street analysts forecast ALMS stock price to rise
7 Buy
0 Hold
0 Sell
Strong Buy
Current: 24.710
sliders
Low
32
Averages
37.57
High
50
Current: 24.710
sliders
Low
32
Averages
37.57
High
50
Raymond James
Strong Buy
maintain
AI Analysis
2026-03-30
Reason
Raymond James
Price Target
AI Analysis
2026-03-30
maintain
Strong Buy
Reason
Raymond James keeps a Strong Buy rating on Alumis (ALMS) following what appears to be a major success at AAD, where Phase 3 data showed envudeucitinib delivering efficacy broadly comparable to Takeda's (TAK) zasocitinib and Johnson & Johnson's (JNJ) icotrokinra, with a more favorable safety profile. Higher adverse event rates and safety concerns for zasocitinib suggest envu holds a competitive advantage, supporting expectations for share appreciation, the analyst tells investors in a research note, adding that the firm expects Alumis shares to trade up on the news. Shares of Alumis are down 11.7% to $21.90 in late morning trading.
Oppenheimer
Oppenheimer
Outperform
maintain
$50 -> $55
2026-03-30
Reason
Oppenheimer
Oppenheimer
Price Target
$50 -> $55
2026-03-30
maintain
Outperform
Reason
Oppenheimer raised the firm's price target on Alumis to $55 from $50 and keeps an Outperform rating on the shares. The firm sees the three new orals for psoriasis - Johnson & Johnson's (JNJ) Ico, Takeda's (TAK) Zaso, and Alumis' (ALMS) Envu - as having similar efficacy, with a benefit towards the latter on quality of life and with a potentially tougher trial population than Zaso. Both Alumis and Takeda clearly demonstrated biologic-like efficacy, and safety which are comparable to J&J's recently approved icotrokinra. Oppenheimer sees this weekend's readout as very positive for Alumis, both directly in PsO, as well as into the Q3 Phase 2 readout in systemic lupus erythematosus.
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