UPB Stock Price Prediction

Upstream Bio Inc

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Advanced Chart

25.550

+0.59(2.364%)1D

1-Day-Price-Prediction

+0.46%

1-Week Prediction

+1.56%

1-Month Prediction

-0.45%

2026 Prediction

-100%

2030 Prediction

-100%

Based on our advanced algorithm, we predict that UPB stock price will experience significant movement in the coming periods. Our 1-day prediction estimates a price of $25.67, while the 1-week outlook suggests a value of $26.07. For the 1-month forecast, we project a price of $25.44. Looking further ahead, our 2026 projection estimates a value of $0.00, with a long-term 2030 forecast reaching $0.00. Stay informed and make strategic decisions with our data-driven insights!

Unlock Free Stock Price Forecast

25.440

Should I Buy Upstream Bio Inc Stock?

Based on our evaluation of the five key dimensions—Technical Signals, Moving Average trends, Short Sell Data, Similar Chart Pattern Matching and Seasonality Analysis—we have identified the following insights. UPB has several positive signals and is within a rising trend, so we believe it will perform strongly in the next couple of days or weeks. We therefore hold a positive evaluation of this stock. Our analysis conclusion for this stock is a Strong Buy candidate.

UPB stock price ended at $25.55 on Friday, after rising 2.36%

The Upstream Bio Inc stock price increased by 2.36% on the last trading day (21 Nov 2025), rising from 24.71 to 25.55. Throughout the last trading session, the stock experienced a fluctuation of 8.21% , ranging from a day low of $24.12 to a day high of 26.1. The price has declined in 4 of the last 10 days, resulting in a total change of 11.28% during this period. On the last day, trading volume decrease by -17.82K shares, with the rising prices. This could serve as an early warning, indicating that risk may slightly increase in the coming days. In total, 384.49K shares were traded, amounting to approximately 9.84M.

UPB Technical Signals

UPB(Upstream Bio Inc Corp) has 5 buy signals and 1 sell signal now. The current trend is an uptrend starting from 2025-11-07. The total price change during this trend is +11.28%. Recently, the price has increased while volume droped, indicating a potential warning signal. The average turnover of UPB over the last 5 trading days is 11.78M. Overall, the technical indicator signals lean more toward a Bullish outlook in the mid-term.

UPB Moving Average Analysis

Upstream Bio Inc's overall moving average trend leans more bullish as of Saturday, November 22, 2025, with 0 negative signals and 4 positive signal. In the mid-term, the SMA_20 being above the SMA_60 signals a strong bullish trend. There will be some resistance from the lines at $26.68, and $28.06. A break-up above any of these levels will issue buy signals. There will be some support from the lines at $22.22, and $20.84. A break-down below any of these levels will issue sell signals.

UPB Short Selling Analysis

The short sale ratio of Upstream Bio Inc(UPB) as of 18 Nov 2025 is 12.69%, dropping from last trading day. With decreasing price from 25.70 to 25.56. The short sell activity indicate that short sellers may be anticipating price hit a bottom.

Technical Signal

Technical Signals Summary

Strong buy

Sell

Buy

Moving Average

Swing

Positive

Stock Price Above SMA_5

Short Term

Positive

SMA_5 Above SMA_20

Mid Term

Positive

SMA_20 Above SMA_60

Long Term

Positive

SMA_60 Above SMA_200

Short Selling

Close Price

Short Sale Ratio

Short Sale Volume

5 Bullish Signals

When Value satisfies Signal, Indicator signals Bullish

Indicators

Signal

Value

Meaning

Awesome Oscillator (5, 34)

AO_5_34 > 0

2.27

Bullish

Momentum (10 days)

MOM_10 > 0

2.59

Bullish

Moving Average Convergence Divergence (12, 26, 9)

MACD_12_26_9 > 0

1.027

Bullish

Moving Average

Price crosses above 5-day SMA

Bullish

Moving Average

10-day SMA crosses above 20-day SMA

Bullish

1 Bearish Signals

When Value satisfies Signal, Indicator signals Bearish

Indicators

Signal

Value

Meaning

Williams %R (14 days)

WILLR_14 > -20

-15.403

Bearish

UPB Stock Forecast

2026

2027

2028

2029

2030

2031

2032

2033

2034

2035

Month	Min. Price	Avg. Price	Max. Price	Potential ROI
Month	Min. Price	Avg. Price	Max. Price	Potential ROI
No data

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In 2026, Upstream Bio Inc (UPB) is anticipated to change hands in a trading channel between $0.00 and $0.00.

Upstream Bio Inc Stock Forecast 2026

UPB Price Prediction & Forecast by Similar Chart Analysis

Based on historical patterns and backtesting of stocks with similar movements to Upstream Bio Inc(UPB), our algorithm predicts UPB's 1-month price at $24.53, with an 0.01%upwardshift. Using a similarity score up to 96.92%and other factors, This forecast updates weekly, adjusting for significant deviations.

Similar Chart

The price prediction chart for Upstream Bio Inc (UPB.O) stock, as of Sunday, November 16, 2025 , forecasts a 0.01% change over the next month, based on its high correlation with BLD.N stock patterns. The similarity between their price movements over the analyzed periods is 96.92%. The right panel lists other stocks with similar price patterns. This prediction is updated every week.

UPB

Future prediction

Up: 0.01%

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BLD

Up: 0.01%Similarity: 96.92%

Name

Similarity

Up/Down

BLD.N

96.92%

+0.01%

MREO.O

96.79%

+10.40%

IPAR.O

96.73%

-3.30%

TOYO.O

96.54%

+0.81%

UGP.N

96.42%

+10.37%

BDL.A

96.36%

+11.43%

NAVI.O

96.35%

+3.31%

SLNO.O

96.22%

+24.48%

GRNT.N

96.18%

-5.70%

CME.O

96.18%

-16.83%

UPB Seasonality Analysis

Based on UPB's historical stock price data across all years, the probability of a positive return in November is0.00%, suggesting it maynotbe an ideal month to invest in UPB. In contrast,Apriloffers the highest probability of positive returns at100.00%, making it a potentially strong month for investment.

However, this is only a prediction based on one method, and a comprehensive assessment of the stock's future trend should consider additional factors. Our final stock price commentary incorporates three main evaluation dimensions: technical signals, Moving Average trends, and similar chart pattern matching, with the first two dimensions carrying the primary weight to ensure a more robust and accurate forecast.

Monthly Seasonality

The radar chart shows that buying Upstream Bio Inc (UPB.O) stock in April has the highest probability of a positive return (100.00%), while January has the lowest probability (0.00%).

Performance Seasonality

The chart shows Upstream Bio Inc. (UPB)'s annual stock price return for the past three years, helping you analyze price trends and identify recurring trends on an annual basis.