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TVRD Overview

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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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ET
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Intellectia

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High
3.980
Open
3.980
VWAP
3.90
Vol
41.55K
Mkt Cap
36.49M
Low
3.830
Amount
162.03K
EV/EBITDA(TTM)
--
Total Shares
9.38M
EV
314.87K
EV/OCF(TTM)
--
P/S(TTM)
--
Tvardi Therapeutics, Inc., formerly Cara Therapeutics, Inc., is a clinical-stage biopharmaceutical company focused on the development of novel, oral, small molecule therapies targeting (STAT3) to treat fibrosis-driven diseases with significant unmet need. STAT3 is a central mediator across critical fibrotic signaling pathways that drive uncontrolled deposition, proliferation, survival and immune suppression. STAT3 is also positioned at the intersection of many signaling pathways integral to the survival and immune evasion of cancer cells. Its product candidate, TTI-101, is in Phase 2 clinical development for the treatment of fibrosis-driven diseases, with an initial focus on idiopathic pulmonary fibrosis (IPF), and hepatocellular carcinoma (HCC). Its second product candidate, TTI-109, is an oral, small-molecule, which is structurally related to, yet chemically distinct from, TTI-101 and is designed to enhance the ability to target STAT3.
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Events Timeline

(ET)
2026-01-08
08:30:00
Tvardi Therapeutics Updates on TTI-101 Clinical Trial Progress
select
2025-11-13 (ET)
2025-11-13
16:03:51
Tvardi Therapeutics Announces Q3 EPS of 59c, Below Consensus Estimate of 96c
select
2025-10-13 (ET)
2025-10-13
07:45:21
Tvardi Reports No Observed Benefit of TTI-101 Treatment in REVERT Trial
select

News

Globenewswire
2.0
01-08Globenewswire
Tvardi to Present TTI-101 Clinical Data at 44th J.P. Morgan Healthcare Conference
  • Clinical Trial Progress: Tvardi Therapeutics will present new Phase 2 REVERT IPF clinical trial data for TTI-101 at the 44th J.P. Morgan Healthcare Conference on January 15, 2026, demonstrating encouraging signals across fibrosis, inflammatory markers, and pulmonary function, further supporting TTI-101's efficacy in inhibiting STAT3.
  • Market Demand Alignment: TTI-101, an innovative therapy targeting fibrosis-driven diseases, addresses the urgent need for effective treatment options in the clinical landscape, potentially bolstering the company's market position in the biopharmaceutical sector.
  • Investor Engagement: The conference will provide a webcast for investors to access detailed information about TTI-101, likely attracting increased investor interest in Tvardi's clinical advancements and future potential.
  • Strategic Positioning: Tvardi's focus on developing small molecule therapies targeting STAT3 highlights its strategic importance in addressing unmet medical needs in fibrosis diseases, which may present long-term growth opportunities for the company.
Globenewswire
7.0
2025-12-24Globenewswire
Tvardi Therapeutics Shares Plunge 80% Following Disappointing Phase 2 Trial Data
  • Stock Plunge: Tvardi Therapeutics experienced an over 80% drop in share price on October 13, 2025, following disappointing preliminary data from its Phase 2 REVERT clinical trial, which is likely to severely impact investor confidence and may lead to further legal actions.
  • Trial Failure: The trial aimed to assess the safety and efficacy of TTI-101 in patients with idiopathic pulmonary fibrosis, but preliminary results indicated that it did not meet its goals, potentially affecting the company's future R&D direction and funding inflow.
  • Investor Losses: Faruqi & Faruqi LLP is investigating potential claims against Tvardi, encouraging investors who suffered significant losses to reach out, highlighting the legal risks that could exacerbate the financial pressures faced by the company.
  • Market Reaction: The poor clinical trial results may lead to substantial losses for Tvardi's shareholders, further impacting the company's reputation and market position within the biopharmaceutical industry.
PRnewswire
7.0
2025-12-23PRnewswire
Faruqi & Faruqi Investigates Potential Claims Against Tvardi Therapeutics (NASDAQ:TVRD)
  • Legal Investigation Initiated: Faruq & Faruqi, LLP is investigating potential claims against Tvardi Therapeutics, indicating that the company may face legal risks which could undermine investor confidence.
  • Investor Losses Highlighted: The firm encourages investors who suffered significant losses in Tvardi stock or options to contact them directly, demonstrating a commitment to protecting investor rights and potentially leading to increased legal actions from affected investors.
  • Industry Impact Assessment: As a leading national securities law firm, Faruqi & Faruqi has recovered hundreds of millions for investors since its founding in 1995, showcasing its influence and expertise in the industry, which may negatively affect Tvardi's market performance.
  • Legal Consultation Channels: Investors can reach out via 877-247-4292 or 212-983-9330 for legal advice, providing a clear pathway for affected investors to take action, potentially increasing the number of claims filed against Tvardi.
Businesswire
7.0
2025-12-21Businesswire
Tvardi Therapeutics Shares Plunge 80% Following Phase 2 Trial Disappointment
  • Stock Plunge: Tvardi Therapeutics, Inc. shares plummeted over 80% on October 13, 2025, following disappointing preliminary data from the Phase 2 REVERT clinical trial, significantly undermining investor confidence.
  • Trial Failure: The study aimed to assess the safety and efficacy of TTI-101 in patients with idiopathic pulmonary fibrosis, but preliminary results indicated that it did not meet its goals, potentially necessitating major adjustments in the company's future R&D direction.
  • Patient Characterization Analysis: While baseline characteristics were similar across treatment arms, the lower percent predicted FVC in the placebo group raises concerns about the drug's efficacy, increasing uncertainty for investors regarding future outcomes.
  • Legal Investigation Initiated: Faruq & Faruqi LLP has launched an investigation into potential claims against Tvardi, highlighting growing market concerns about the company's future legal risks and financial liabilities.
Globenewswire
7.0
2025-12-20Globenewswire
Tvardi Therapeutics Shares Plunge 80% After Phase 2 Trial Disappointment
  • Stock Plunge: Tvardi Therapeutics, Inc. experienced an over 80% drop in share price on October 13, 2025, following disappointing preliminary data from the Phase 2 REVERT clinical trial of TTI-101 for idiopathic pulmonary fibrosis, significantly undermining investor confidence.
  • Clinical Trial Failure: The trial aimed to assess the safety and pharmacokinetics of TTI-101, but preliminary results indicated that it failed to meet its goals, particularly regarding changes in Forced Vital Capacity (FVC), highlighting major challenges in the company's R&D efforts.
  • Investor Losses: In light of the sharp decline in stock price, Faruqi & Faruqi LLP is investigating potential claims against Tvardi, encouraging investors who suffered significant losses to contact them to discuss legal options, indicating an increase in legal risks for the company.
  • Market Reaction: This incident not only impacts Tvardi's market performance but may also have profound implications for its future financing and R&D capabilities, leading to a significant decline in investor confidence regarding the company's prospects.
PRnewswire
7.0
2025-12-17PRnewswire
Faruqi & Faruqi Investigates Claims for Investors in Tvardi Therapeutics Following Significant Losses
  • Legal Investigation Initiated: Faruq & Faruq LLP is investigating potential claims against Tvardi Therapeutics, Inc., aiming to provide legal support for investors who have suffered significant losses, indicating that the company faces legal risks that could impact its stock performance.
  • Investor Rights Protection: The firm encourages investors who have incurred substantial losses in Tvardi stock or options to contact them directly to discuss their legal rights, demonstrating a commitment to safeguarding investor interests.
  • Industry Impact Analysis: Since its founding in 1995, Faruq & Faruq has recovered hundreds of millions of dollars for investors, highlighting its expertise and influence in securities law, which may negatively affect market confidence in Tvardi.
  • Legal Service Expansion: The firm's investigation spans New York, Pennsylvania, California, and Georgia, indicating its capability to provide legal services nationwide, potentially attracting more affected investors seeking legal assistance.
Wall Street analysts forecast TVRD stock price to rise
6 Analyst Rating
Wall Street analysts forecast TVRD stock price to rise
2 Buy
4 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
4.00
Averages
9.00
High
15.00
Current: 0.000
sliders
Low
4.00
Averages
9.00
High
15.00
Lucid Capital
Neutral -> Buy
upgrade
$6
AI Analysis
2026-02-04
Reason
Lucid Capital
Price Target
$6
AI Analysis
2026-02-04
upgrade
Neutral -> Buy
Reason
Lucid Capital upgraded Tvardi Therapeutics to Buy from Neutral with a $6 price target. The firm finds the stock undervalued at current levels. Lucid's model suggests TTI-101 in hepatocellular carcinoma and TTI-109 could be worth $6 per share. Tvardi is currently trading near its cash value levels, the analyst tells investors in a research note. Lucid cites valuation and the potential for Tvardi's assets to inflect the story with key readouts this year for the upgrade.
Raymond James
Outperform -> Market Perform
downgrade
2025-10-14
Reason
Raymond James
Price Target
2025-10-14
downgrade
Outperform -> Market Perform
Reason
Raymond James downgraded Tvardi Therapeutics to Market Perform from Outperform without a price target. The firm believes many open questions remain regarding TTI-101 following the unsuccessful REVERT-IPF readout. The discontinuation rate seen in the readout adds risk to this program, the analyst tells investors in a research note. Raymond James downgraded Tvardi to reflect the removal of the idiopathic pulmonary fibrosis opportunity and uncertainty on the path forward.
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Valuation Metrics

The current forward P/E ratio for Tvardi Therapeutics Inc (TVRD.O) is -1.65, compared to its 5-year average forward P/E of -5.57. For a more detailed relative valuation and DCF analysis to assess Tvardi Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.57
Current PE
-1.65
Overvalued PE
-1.34
Undervalued PE
-9.80

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

Whales Holding TVRD

S
Slate Path Capital LP
Holding
TVRD
+17.61%
3M Return

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Frequently Asked Questions

What is Tvardi Therapeutics Inc (TVRD) stock price today?

The current price of TVRD is 3.89 USD — it has decreased -0.77

What is Tvardi Therapeutics Inc (TVRD)'s business?

Tvardi Therapeutics, Inc., formerly Cara Therapeutics, Inc., is a clinical-stage biopharmaceutical company focused on the development of novel, oral, small molecule therapies targeting (STAT3) to treat fibrosis-driven diseases with significant unmet need. STAT3 is a central mediator across critical fibrotic signaling pathways that drive uncontrolled deposition, proliferation, survival and immune suppression. STAT3 is also positioned at the intersection of many signaling pathways integral to the survival and immune evasion of cancer cells. Its product candidate, TTI-101, is in Phase 2 clinical development for the treatment of fibrosis-driven diseases, with an initial focus on idiopathic pulmonary fibrosis (IPF), and hepatocellular carcinoma (HCC). Its second product candidate, TTI-109, is an oral, small-molecule, which is structurally related to, yet chemically distinct from, TTI-101 and is designed to enhance the ability to target STAT3.

What is the price predicton of TVRD Stock?

Wall Street analysts forecast TVRD stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for TVRD is9.00 USD with a low forecast of 4.00 USD and a high forecast of 15.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Tvardi Therapeutics Inc (TVRD)'s revenue for the last quarter?

Tvardi Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Tvardi Therapeutics Inc (TVRD)'s earnings per share (EPS) for the last quarter?

Tvardi Therapeutics Inc. EPS for the last quarter amounts to -0.59 USD, decreased -72.43

How many employees does Tvardi Therapeutics Inc (TVRD). have?

Tvardi Therapeutics Inc (TVRD) has 10 emplpoyees as of March 17 2026.

What is Tvardi Therapeutics Inc (TVRD) market cap?

Today TVRD has the market capitalization of 36.49M USD.