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TSHA Should I Buy

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Intellectia

Should You Buy Taysha Gene Therapies Inc (TSHA) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
4.070
1 Day change
52 Week Range
6.020
Analysis Updated At
2026/03/27
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Taysha Gene Therapies Inc (TSHA) is not a strong buy at the moment for a beginner investor with a long-term focus. While the company has shown significant revenue growth and positive momentum in its Rett syndrome study, the technical indicators and options data suggest a lack of immediate upward momentum. Additionally, there are no strong proprietary trading signals or recent news catalysts to support a buy decision right now.

Technical Analysis

The MACD is negatively expanding, RSI is neutral at 43.74, and moving averages are converging, indicating no clear trend. The stock is trading near its pivot level (4.416) with support at 4.171 and resistance at 4.66, suggesting limited immediate upside.

Options Data

Bullish
Open Interest Put-Call Ratio
Bearish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
5
Buy
7

Positive Catalysts

  • Hedge funds have significantly increased their buying activity by 649.63% over the last quarter. Analysts have raised the price target to $11, citing momentum in the Rett syndrome study and alignment with the FDA.

Neutral/Negative Catalysts

  • Pre-market price is down by 0.69%. Technical indicators do not show a clear upward trend. Options data indicates higher put volume relative to calls, suggesting bearish sentiment.

Financial Performance

In Q4 2025, revenue increased by 171.27% YoY to $5,485,000. Net income improved by 48.26% YoY but remains negative at -$27,851,000. EPS improved by 14.29% YoY to -0.08. Gross margin remains strong at 100%.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Wells Fargo maintains an Overweight rating and raised the price target from $8 to $11, expecting another year of outperformance driven by the Rett syndrome study.

Wall Street analysts forecast TSHA stock price to rise
11 Analyst Rating
Wall Street analysts forecast TSHA stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 4.070
sliders
Low
8
Averages
11.6
High
19
Current: 4.070
sliders
Low
8
Averages
11.6
High
19
Wells Fargo
Zachary Fadem
Overweight
maintain
$8 -> $11
AI Analysis
2026-01-05
Reason
Wells Fargo
Zachary Fadem
Price Target
$8 -> $11
AI Analysis
2026-01-05
maintain
Overweight
Reason
Wells Fargo analyst Zachary Fadem raised the firm's price target on Taysha Gene Therapies to $11 from $8 and keeps an Overweight rating on the shares. The firm sees another year of outperformance for the stock, driven by continued momentum in the company's pivotal Rett syndrome study following last year's alignment with FDA on a favorable design.
Goldman Sachs
Salveen Richter
Early-Stage Biotech -> Buy
upgrade
$11
2025-12-04
Reason
Goldman Sachs
Salveen Richter
Price Target
$11
2025-12-04
upgrade
Early-Stage Biotech -> Buy
Reason
Goldman Sachs analyst Salveen Richter moved its rating on Taysha Gene Therapies to Buy with an $11 price target from Early-Stage Biotech designation. The firm is positive on the company's outlook in Rett syndrome. believe Taysha can achieve the response rate of 33% needed to meet the minimum threshold for success in the REVEAL study, the analyst tells investors in a research note.
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