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TPST Should I Buy

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Intellectia

Should You Buy Tempest Therapeutics Inc (TPST) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
1.630
1 Day change
-0.61%
52 Week Range
12.230
Analysis Updated At
2026/03/27
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Tempest Therapeutics Inc (TPST) is not a strong buy at the moment for a beginner investor with a long-term focus. The stock is currently in a bearish technical trend, and while there are positive insider buying signals and strategic moves to extend its cash runway, the company's financial performance is weak, and the stock lacks strong trading signals or immediate catalysts for significant upward momentum.

Technical Analysis

The stock is in a bearish trend with the MACD histogram below 0 and negatively expanding. RSI at 16.536 indicates the stock is oversold, but the moving averages (SMA_200 > SMA_20 > SMA_5) confirm a bearish setup. The stock is trading near its support level of 1.74, with resistance at 2.01.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
9
Buy
3

Positive Catalysts

  • Insider buying by the CEO, which is generally viewed as a positive signal.

  • Strategic acquisition of Factor Bioscience's CAR-T programs, extending the cash runway into 2027 and expanding the pipeline.

  • Potential for short-term price increases based on historical candlestick pattern analysis.

Neutral/Negative Catalysts

  • Weak financial performance with a significant decline in net income (-66.74% YoY) and EPS (-85.15% YoY).

  • Recent stock price volatility due to financing announcements and dilution concerns.

  • Lack of significant hedge fund or insider trading trends.

Financial Performance

The company's financials for Q3 2025 show no revenue growth (0% YoY), a significant drop in net income to -$3.51 million (-66.74% YoY), and a sharp decline in EPS to -0.79 (-85.15% YoY). Gross margin remains at 0%, indicating no profitability.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

H.C. Wainwright recently upgraded the stock to Buy with an $11 price target, citing the strategic acquisition of CAR-T programs and the company's renewed focus. However, this is based on long-term potential rather than immediate performance.

Wall Street analysts forecast TPST stock price to rise
Analyst Rating
0
Wall Street analysts forecast TPST stock price to rise
Buy
Hold
Sell
0
Current: 1.640
sliders
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0
Averages
0
High
0
0
Current: 1.640
sliders
Low
0
Averages
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High
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H.C. Wainwright
Joseph Pantginis
Neutral -> Buy
upgrade
$11
AI Analysis
2026-01-22
Reason
H.C. Wainwright
Joseph Pantginis
Price Target
$11
AI Analysis
2026-01-22
upgrade
Neutral -> Buy
Reason
H.C. Wainwright analyst Joseph Pantginis upgraded Tempest Therapeutics to Buy from Neutral with an $11 price target. The company's acquisition of Factor Bioscience's CAR-T programs is a "shrewd and necessary move" to extend its "critically short cash runway into 2027," the analyst tells investors in a research note. The firm Tempest's strategic pivot also expands the company's pipeline with a "clinically de-risked" cell therapy asset TPST-2003. It cites Tempest's renewed strategic focus and market opportunity for the upgrade.
HC Wainwright & Co.
Joseph Pantginis
Strong Buy
to
Hold
Downgrades
$16
2025-04-10
Reason
HC Wainwright & Co.
Joseph Pantginis
Price Target
$16
2025-04-10
Downgrades
Strong Buy
to
Hold
Reason
Tempest Therapeutics announced that the company plans to explore a full range of strategic alternatives to advance its clinical stage programs. Strategic alternatives under consideration may include, but are not limited to, mergers, acquisition, partnerships, joint ventures, licensing arrangements or other strategic transactions. The company has retained MTS Health Partners, a financial advisor with experience in the biotechnology industry, to support it with the strategic evaluation process. "Notwithstanding the positive randomized data set from the amezalpat Phase 2 and its blockbuster potential in first-line HCC, as well as the potential of TPST-1495 as it moves towards a Phase 2 in FAP, the capital markets have been unavailable to support the next stage of advancement," said Stephen Brady, president and chief executive officer of Tempest. "We are initiating a process to explore alternatives available to the company to maximize stockholder value, which include finding a strategic partner with the resources to develop what we believe are potentially life-saving therapies for patients in need. Given the positive data and commercial potential with this pipeline, as well as the clearance from FDA on the lead program's pivotal study, we believe this is a rare opportunity for a partner."
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