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TPST Should I Buy

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Intellectia

Should You Buy Tempest Therapeutics Inc (TPST) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
2.400
1 Day change
52 Week Range
12.230
Analysis Updated At
2026/03/06
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Tempest Therapeutics Inc (TPST) is not a strong buy for a beginner investor with a long-term focus at this time. While the stock has potential upside due to its strategic pivot and analyst upgrade, the company's financial performance is weak, and there are no significant positive trading signals or recent catalysts to justify an immediate investment. Holding off for more clarity on financial improvements or stronger trading signals is recommended.

Technical Analysis

The technical indicators for TPST are mixed. The MACD is positive and expanding, which is a bullish sign, but the RSI is neutral at 46.878, and the moving averages are bearish (SMA_200 > SMA_20 > SMA_5). The stock is trading near its pivot level of 2.319, with support at 2.168 and resistance at 2.47. Overall, the technical setup does not strongly support a buy decision.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
6
Buy
4

Positive Catalysts

  • Analyst upgrade to 'Buy' with an $11 price target, citing the acquisition of Factor Bioscience's CAR-T programs and a strategic pivot.

  • Potential for a 6.08% increase in the next month based on historical candlestick patterns.

Neutral/Negative Catalysts

  • Weak financial performance in Q3 2025, with a significant drop in net income (-66.74% YoY) and EPS (-85.15% YoY).

  • Lack of recent news or significant insider/hedge fund activity.

  • No recent congress trading data or influential figure transactions.

Financial Performance

In Q3 2025, Tempest Therapeutics reported no revenue growth (0.00% YoY), a sharp decline in net income (-66.74% YoY), and a significant drop in EPS (-85.15% YoY). Gross margin remained at 0%. The financial performance indicates weak fundamentals.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

H.C. Wainwright analyst Joseph Pantginis upgraded TPST to 'Buy' from 'Neutral' with an $11 price target. The upgrade is based on the company's acquisition of Factor Bioscience's CAR-T programs, which is seen as a strategic move to extend its cash runway and expand its pipeline with a clinically de-risked asset.

Wall Street analysts forecast TPST stock price to rise
Analyst Rating
0
Wall Street analysts forecast TPST stock price to rise
Buy
Hold
Sell
0
Current: 2.400
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0
Averages
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High
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Current: 2.400
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H.C. Wainwright
Joseph Pantginis
Neutral -> Buy
upgrade
$11
AI Analysis
2026-01-22
Reason
H.C. Wainwright
Joseph Pantginis
Price Target
$11
AI Analysis
2026-01-22
upgrade
Neutral -> Buy
Reason
H.C. Wainwright analyst Joseph Pantginis upgraded Tempest Therapeutics to Buy from Neutral with an $11 price target. The company's acquisition of Factor Bioscience's CAR-T programs is a "shrewd and necessary move" to extend its "critically short cash runway into 2027," the analyst tells investors in a research note. The firm Tempest's strategic pivot also expands the company's pipeline with a "clinically de-risked" cell therapy asset TPST-2003. It cites Tempest's renewed strategic focus and market opportunity for the upgrade.
HC Wainwright & Co.
Joseph Pantginis
Strong Buy
to
Hold
Downgrades
$16
2025-04-10
Reason
HC Wainwright & Co.
Joseph Pantginis
Price Target
$16
2025-04-10
Downgrades
Strong Buy
to
Hold
Reason
Tempest Therapeutics announced that the company plans to explore a full range of strategic alternatives to advance its clinical stage programs. Strategic alternatives under consideration may include, but are not limited to, mergers, acquisition, partnerships, joint ventures, licensing arrangements or other strategic transactions. The company has retained MTS Health Partners, a financial advisor with experience in the biotechnology industry, to support it with the strategic evaluation process. "Notwithstanding the positive randomized data set from the amezalpat Phase 2 and its blockbuster potential in first-line HCC, as well as the potential of TPST-1495 as it moves towards a Phase 2 in FAP, the capital markets have been unavailable to support the next stage of advancement," said Stephen Brady, president and chief executive officer of Tempest. "We are initiating a process to explore alternatives available to the company to maximize stockholder value, which include finding a strategic partner with the resources to develop what we believe are potentially life-saving therapies for patients in need. Given the positive data and commercial potential with this pipeline, as well as the clearance from FDA on the lead program's pivotal study, we believe this is a rare opportunity for a partner."
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