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TPST Overview

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Intellectia

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High
2.430
Open
2.420
VWAP
2.40
Vol
42.96K
Mkt Cap
32.35M
Low
2.370
Amount
103.09K
EV/EBITDA(TTM)
--
Total Shares
13.48M
EV
24.16M
EV/OCF(TTM)
--
P/S(TTM)
--
Tempest Therapeutics, Inc. is a clinical-stage biotechnology company advancing a diverse portfolio of small molecule product candidates containing tumor-targeted and/or immune-mediated mechanisms with the potential to treat a range of tumors. Its two clinical-stage therapeutic product candidates are Amezalpat and TPST-1495. Amezalpat is an oral, small molecule, selective antagonist of peroxisome proliferator-activated receptor alpha. The ongoing global randomized Phase Ib/II trial of Amezalpat combined with the standard-of-care first-line regimen of atezolizumab and bevacizumab in patients with advanced or metastatic hepatocellular carcinoma. The Company’s second clinical program, TPST-1495, a dual antagonist of the EP2 and EP4 receptors of prostaglandin E2, a pathway implicated in multiple cancers.
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Events Timeline

(ET)
2026-03-11
08:10:00
Tempest Therapeutics Selects Cincinnati Children's as Lead Partner for TPST-2003
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2026-02-25 (ET)
2026-02-25
08:10:00
Tempest Therapeutics Announces Clinical Data for TPST-2003
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2025-12-09 (ET)
2025-12-09
17:00:00
Tempest Therapeutics Files to Sell 1.17M Shares of Common Stock
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2025-11-25 (ET)
2025-11-25
08:04:50
Tempest Therapeutics sets price for 1.17 million shares at $3.63 in direct registered offering
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2025-11-05 (ET)
2025-11-05
08:31:47
Tempest Therapeutics Announces Q3 EPS of (79c) Compared to ($5.32) in the Previous Year
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2025-08-11 (ET)
2025-08-11
16:54:18
Tempest Therapeutics reports Q2 EPS ($2.07), consensus ($2.65)
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2025-06-30 (ET)
2025-06-30
08:04:14
Tempest Therapeutics receives NMPA clearance to proceed with amezalpat trial
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2025-06-11 (ET)
2025-06-11
08:16:45
Tempest prices 739,000 shares at $6.25 in registered direct offering
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News

Yahoo Finance
8.5
03-11Yahoo Finance
PinnedTempest Selects Cincinnati Children's for Tech Transfer of TPST-2003
  • Tech Transfer Partnership: Tempest Therapeutics has selected Cincinnati Children's Applied Gene and Cell Therapy Center as the lead contract development and manufacturing partner for TPST-2003, with all activities planned for completion by Q3 2026 to support a potential IND filing in Q4 2026, thereby accelerating the clinical development timeline for its CAR-T therapy.
  • Clinical Trial Results: As of January 31, 2026, TPST-2003 has been administered to 36 patients with relapsed/refractory multiple myeloma, achieving a 100% complete response (CR) rate among the six efficacy evaluable patients, indicating strong efficacy in clinical trials and positioning the therapy as a potential class leader in the field.
  • Market Potential: The dual-targeting design of TPST-2003 aims to improve response depth and durability, particularly for patients who have previously received BCMA-targeting CAR-T therapy, showcasing its unique advantages in treating relapsed/refractory multiple myeloma and potentially expanding treatment options for patients.
  • Strategic Development: The collaboration with Cincinnati Children's not only enhances Tempest's technical capabilities in cell therapy but also lays the groundwork for future clinical development, expected to drive the IND application and subsequent market introduction of TPST-2003.
Newsfilter
8.5
02-04Newsfilter
Tempest Acquires CAR-T Assets, Expands Pipeline
  • Transaction Closure: Tempest Therapeutics has completed an all-stock transaction with Factor Bioscience, acquiring dual-targeting CAR-T assets including TPST-2003, which is set for a biologics license application (BLA) in China by 2027, potentially opening new revenue streams and enhancing market competitiveness.
  • Operational Runway Extended: The transaction extends Tempest's operational runway to mid-2027, supporting multiple potential value-generating milestones, with significant clinical advancements expected in the next 12-18 months, thereby boosting investor confidence.
  • New CEO Appointment: Dr. Matt Angel has been appointed as the new President and CEO of Tempest, and his leadership is anticipated to drive innovation in cancer therapies, further strengthening the company's strategic direction and leadership.
  • Clinical Trial Progress: The Phase 1 trial of TPST-2003 in relapsed/refractory multiple myeloma patients has been completed, with data expected in 2026 and a BLA planned for 2027 in China, laying the groundwork for the company's expansion in global markets.
Globenewswire
8.5
01-20Globenewswire
Tempest Therapeutics Announces Warrant Dividend Distribution Date of January 30, 2026
  • Warrant Distribution: Tempest Therapeutics announced a record date of January 30, 2026, for stockholders to receive warrants as a dividend, with distribution expected on February 3, 2026, contingent on closing conditions, aimed at enhancing shareholder value and attracting investor interest.
  • Warrant Terms: Stockholders will receive one warrant for each share held, with an exercise price of $18.48 per share, and the warrants will be valid for five years post-distribution, a strategy likely to boost stock price and market confidence.
  • Shareholder Approval Requirement: The distribution of warrants requires stockholder approval of Proposal 5, reflecting the company's commitment to shareholder engagement and transparency, which aims to build investor trust.
  • Registration Statement Plan: Tempest intends to file a registration statement with the SEC after submitting its 2025 Annual Report to register the common stock underlying the warrants, a move that will support future financing and business expansion, further solidifying its position in the biotechnology sector.
Newsfilter
8.5
2025-11-26Newsfilter
Tempest Therapeutics Closes $4.25 Million Registered Direct Offering
  • Successful Financing: Tempest Therapeutics has completed a registered direct offering of 1,172,414 shares at $3.625 per share, raising approximately $4.25 million, which provides essential liquidity to support its clinical development efforts.
  • Short-Term Warrants Issued: The company concurrently issued short-term unregistered warrants allowing the purchase of the same number of shares at an exercise price of $3.50, potentially generating an additional $4.1 million if fully exercised, enhancing future financial flexibility.
  • Market Compliance: This financing adheres to Nasdaq regulations, ensuring the company's compliance in capital markets, which boosts investor confidence and lays the groundwork for future fundraising efforts.
  • Clear Use of Proceeds: The company intends to use the net proceeds primarily for working capital and general corporate purposes, demonstrating its commitment to ongoing operations and R&D investments aimed at advancing its cancer therapeutics to market.
NASDAQ.COM
5.0
2025-11-24NASDAQ.COM
Butterfly Network and Citius Pharma Boost Biotech Activity in After-Hours Trading
  • Butterfly Network Update: Butterfly Network's shares rose 6.04% after announcing CEO Joseph DeVivo and Interim CFO Megan Carlson will participate in investor meetings at the Evercore Healthcare Conference on December 2, 2025, highlighting their handheld ultrasound technology.

  • Citius Pharmaceuticals Collaboration: Citius Pharmaceuticals saw a 7.90% increase in shares after announcing a collaboration with Verix to utilize its AI-powered Tovana platform for the U.S. commercialization of LYMPHIR, an FDA-approved immunotherapy for cutaneous T-cell lymphoma.

  • General Market Activity: ProQR Therapeutics, Perrigo Company, and Tempest Therapeutics also experienced share price increases, with Tempest announcing plans to acquire CAR-T programs to enhance its pipeline.

  • Other Stocks Performance: Iterum Therapeutics and Processa Pharmaceuticals had minor share price movements without any new updates, reflecting varied investor sentiment in the biotech sector.

Benzinga
4.5
2025-11-19Benzinga
Crude Oil Declines More Than 2%; Lowe's Stock Rises Following Q3 Earnings Report
  • U.S. Stock Market Performance: U.S. stocks showed mixed results, with the Dow Jones down 0.23%, while the NASDAQ and S&P 500 saw slight gains of 0.19% and 0.08%, respectively.

  • Lowe's Earnings Report: Lowe's Companies, Inc. shares rose over 5% after exceeding profit expectations for Q3, reporting adjusted earnings per share of $3.06, although sales fell slightly short.

  • Notable Stock Movements: WeShop Holdings saw a dramatic 413% increase following its Nasdaq debut, while Agios Pharmaceuticals and Carver Bancorp experienced significant declines of 50% and 51%, respectively.

  • Commodity and Economic Updates: Oil prices fell by 2.4% to $59.26, while gold and silver saw slight increases. The U.S. trade deficit narrowed to $59.6 billion in August, with a notable decline in crude oil inventories.

Valuation Metrics

The current forward P/E ratio for Tempest Therapeutics Inc (TPST.O) is -0.19, compared to its 5-year average forward P/E of -1.24. For a more detailed relative valuation and DCF analysis to assess Tempest Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.24
Current PE
-0.19
Overvalued PE
-0.30
Undervalued PE
-2.18

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.69
Current EV/EBITDA
-0.26
Overvalued EV/EBITDA
0.53
Undervalued EV/EBITDA
-1.91

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

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Frequently Asked Questions

What is Tempest Therapeutics Inc (TPST) stock price today?

The current price of TPST is 2.4 USD — it has increased 0

What is Tempest Therapeutics Inc (TPST)'s business?

Tempest Therapeutics, Inc. is a clinical-stage biotechnology company advancing a diverse portfolio of small molecule product candidates containing tumor-targeted and/or immune-mediated mechanisms with the potential to treat a range of tumors. Its two clinical-stage therapeutic product candidates are Amezalpat and TPST-1495. Amezalpat is an oral, small molecule, selective antagonist of peroxisome proliferator-activated receptor alpha. The ongoing global randomized Phase Ib/II trial of Amezalpat combined with the standard-of-care first-line regimen of atezolizumab and bevacizumab in patients with advanced or metastatic hepatocellular carcinoma. The Company’s second clinical program, TPST-1495, a dual antagonist of the EP2 and EP4 receptors of prostaglandin E2, a pathway implicated in multiple cancers.

What is the price predicton of TPST Stock?

Wall Street analysts forecast TPST stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for TPST is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Tempest Therapeutics Inc (TPST)'s revenue for the last quarter?

Tempest Therapeutics Inc revenue for the last quarter amounts to -3.60M USD, decreased -65.91

What is Tempest Therapeutics Inc (TPST)'s earnings per share (EPS) for the last quarter?

Tempest Therapeutics Inc. EPS for the last quarter amounts to -6779000.00 USD, decreased -33.52

How many employees does Tempest Therapeutics Inc (TPST). have?

Tempest Therapeutics Inc (TPST) has 24 emplpoyees as of March 12 2026.

What is Tempest Therapeutics Inc (TPST) market cap?

Today TPST has the market capitalization of 32.35M USD.