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VYNE Overview

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$
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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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ET
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High
0.618
Open
0.614
VWAP
0.61
Vol
198.91K
Mkt Cap
20.15M
Low
0.604
Amount
121.17K
EV/EBITDA(TTM)
--
Total Shares
33.32M
EV
-3.55M
EV/OCF(TTM)
--
P/S(TTM)
46.11
VYNE Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing differentiated therapies to treat chronic inflammatory and immune-mediated conditions with high unmet need. Its lead program is repibresib gel (also known as VYN201), a topically administered, small-molecule pan-BD bromodomain and extra-terminal (BET) inhibitor designed as a soft drug to address diseases involving multiple, diverse inflammatory cell signaling pathways while providing low systemic exposure. Its second program is VYN202, an oral, small-molecule BD2-selective BET inhibitor. The Company has rights to research, develop and commercialize products containing BET inhibitor compounds for the treatment of any disease, disorder or condition in humans. Utilizing its InhiBET platform and through its preclinical and clinical activities, the Company is evaluating the impact that BET inhibitor compounds have on regulating pro-inflammatory cytokines.
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Events Timeline

(ET)
2025-12-17
08:10:00
VYNE and Yarrow Enter Merger Agreement, Expected to Close in 2026
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2025-11-06 (ET)
2025-11-06
08:06:45
VYNE Therapeutics announces Q3 earnings per share of 17 cents, compared to a loss of 29 cents in the same period last year.
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2025-08-14 (ET)
2025-08-14
08:03:55
VYNE Therapeutics reports Q2 EPS (13c) vs (22c) last year
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2025-07-30 (ET)
2025-07-30
08:21:08
VYNE says Phase 2B trial with repibresib gel did not meet primary endpoint
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2025-07-02 (ET)
2025-07-02
11:02:09
H.C. Wainwright 'encouraged' by VYNE Therapeutics VYN202 update
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2025-07-02
07:49:07
VYNE Therapeutics provides program update on VYN202 following clinical hold
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2025-05-08 (ET)
2025-05-08
08:04:02
VYNE Therapeutics reports Q1 EPS (20c) vs (15c) last year
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News

Globenewswire
8.5
2025-12-20Globenewswire
Amicus Therapeutics to Sell to BioMarin for $14.50 per Share
  • Legal Investigation Initiated: Halper Sadeh LLC is investigating Amicus Therapeutics (NASDAQ: FOLD) regarding its sale to BioMarin Pharmaceutical Inc. at $14.50 per share, which may involve potential violations of federal securities laws, potentially impacting shareholder rights if findings are unfavorable.
  • Merger Impact Analysis: The merger between VYNE Therapeutics Inc. (NASDAQ: VYNE) and Yarrow Bioscience, Inc. is expected to result in VYNE shareholders owning only about 3% of the combined entity, raising concerns about the perceived value of the merger and potentially affecting shareholder confidence.
  • Shareholder Rights Protection: The sale of Heritage Commerce Corp (NASDAQ: HTBK) for 0.6500 shares of CVB Financial Corp. common stock is under scrutiny, with Halper Sadeh LLC potentially seeking increased compensation for shareholders to ensure their interests are safeguarded in the transaction.
  • Legal Support for Merger Transactions: The merger of Farmers National Banc Corp. (NASDAQ: FMNB) with Middlefield Banc Corp. is also being investigated, with Halper Sadeh LLC providing legal support to help shareholders understand their rights and options, ensuring transparency and fairness in the process.
PRnewswire
7.0
2025-12-19PRnewswire
Ademi Firm Investigates VYNE for Potential Fiduciary Breaches in Yarrow Transaction
  • Shareholder Rights Investigation: The Ademi Firm is investigating VYNE's transaction with Yarrow Bioscience for potential breaches of fiduciary duty, which could undermine shareholder trust in corporate governance.
  • Shareholder Structure Shift: Post-transaction, VYNE shareholders are expected to own approximately 3% of the combined entity, while Yarrow shareholders will hold about 97%, significantly diminishing VYNE shareholders' control.
  • Competitive Transaction Restrictions: The transaction agreement imposes significant penalties on VYNE for accepting competing bids, potentially harming shareholder interests and limiting the company's strategic options in the future.
  • Board Accountability Review: The Ademi Firm is examining the conduct of VYNE's board to determine if they are fulfilling their fiduciary duties to all shareholders, which could impact the company's governance structure and future decision-making.
PRnewswire
7.0
2025-12-17PRnewswire
Monteverde & Associates Investigates VYNE Therapeutics Merger with Yarrow Bioscience
  • Shareholder Rights Protection: Monteverde & Associates is investigating the merger between VYNE Therapeutics and Yarrow Bioscience, with VYNE shareholders expected to own 3% of the combined entity, raising concerns about the fairness of the deal.
  • Law Firm Credibility: The firm has been recognized as a Top 50 firm in the 2024 ISS Securities Class Action Services Report, highlighting its successful track record in protecting shareholder rights and enhancing its influence in such cases.
  • Merger Transaction Transparency: The law firm urges common stockholders of VYNE to scrutinize the fairness of the merger and offers free consultations, aiming to ensure that shareholders' interests are adequately protected in the transaction.
  • National Impact: Headquartered in the Empire State Building, Monteverde & Associates, as a national class action securities firm, boasts a successful litigation history that instills confidence in shareholders, indicating its broad influence in the legal field.
Benzinga
9.5
2025-12-17Benzinga
Crude Oil Increases by More Than 1%; General Mills Reports Earnings Exceeding Expectations
  • U.S. Stock Market Performance: U.S. stocks declined mid-session, with the Nasdaq Composite dropping over 1%, while the Dow and S&P 500 also experienced losses. Energy shares rose by 1.3%, but information technology stocks fell by 1.8%.

  • General Mills Earnings Report: General Mills reported better-than-expected second-quarter earnings of $1.10 per share, surpassing analyst estimates, despite a 7% year-over-year decline in quarterly sales.

  • Notable Stock Movements: Vyne Therapeutics saw a 57% increase in shares after announcing a merger, while Udemy's shares surged 27% following a merger agreement with Coursera. Conversely, Vistagen Therapeutics shares plummeted 81% after failing to meet study endpoints.

  • Global Market Trends: European shares mostly rose, with the eurozone's STOXX 600 gaining 0.39%, while Asian markets closed higher, led by Japan's Nikkei and China's Shanghai Composite.

Benzinga
4.5
2025-12-17Benzinga
Dow Rises by 150 Points as Jabil Reports Positive Earnings
  • U.S. Stock Market Performance: U.S. stocks saw gains, with the Dow Jones rising approximately 150 points, while the NASDAQ and S&P 500 also experienced slight increases. Energy shares led the rise, up by 1%, while information technology stocks fell by 0.1%.

  • Earnings Reports: Jabil Inc reported better-than-expected earnings for its first quarter, with adjusted earnings of $2.85 per share, surpassing estimates. In contrast, Children's Place Inc faced a significant drop in shares following disappointing third-quarter results.

  • Notable Stock Movements: Vyne Therapeutics shares surged 66% after announcing a merger agreement, while Agape ATP Corp and Aditxt Inc also saw substantial increases in their stock prices. Conversely, Vistagen Therapeutics experienced a dramatic 79% drop after failing to meet study endpoints.

  • Global Market Trends: European shares were mixed, with the STOXX 600 gaining slightly, while Asian markets mostly closed higher, led by Japan and Hong Kong. Additionally, mortgage applications in the U.S. fell by 3.8% in the latest week.

Newsfilter
8.5
2025-12-17Newsfilter
Yarrow and VYNE Merge, Anticipating $200 Million Financing
  • Merger Agreement Reached: Yarrow Bioscience and VYNE Therapeutics have entered into a merger agreement expected to close in Q2 2026, which will position Yarrow as a company focused on autoimmune thyroid diseases, significantly enhancing its market competitiveness.
  • Financing Support: Prior to the merger, Yarrow secured approximately $200 million in financing from investors including RTW Investments, which is expected to fund operations into 2028, thereby accelerating the clinical development of its lead product YB-101.
  • Clinical Trial Plans: Post-merger, YB-101 is set to enter a U.S.-based Phase 1b/2b trial, with preliminary data anticipated in the second half of 2027, providing new hope for the treatment of Graves' disease and thyroid eye disease.
  • Shareholder Value Enhancement: VYNE plans to distribute approximately $14.5 to $16.5 million in cash dividends to shareholders before the merger, aiming to create both short- and long-term value through cash dividends and the potential breakthrough therapies from Yarrow.
Wall Street analysts forecast VYNE stock price to rise
2 Analyst Rating
Wall Street analysts forecast VYNE stock price to rise
1 Buy
1 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
2.00
Averages
2.00
High
2.00
Current: 0.000
sliders
Low
2.00
Averages
2.00
High
2.00
H.C. Wainwright
Joseph Pantginis
Buy
to
Neutral
downgrade
AI Analysis
2025-07-30
Reason
H.C. Wainwright
Joseph Pantginis
Price Target
AI Analysis
2025-07-30
downgrade
Buy
to
Neutral
Reason
H.C. Wainwright analyst Joseph Pantginis downgraded VYNE Therapeutics to Neutral from Buy.
H.C. Wainwright
H.C. Wainwright
Buy
to
Neutral
downgrade
$4.50
2025-07-30
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$4.50
2025-07-30
downgrade
Buy
to
Neutral
Reason
H.C. Wainwright downgraded VYNE Therapeutics to Neutral from Buy and removed the firm's prior $4.50 price target after the company's Phase 2b trial assessing repibresib in nonsegmental vitiligo did not achieve its primary endpoint and also missed the secondary endpoint. The Phase 2b result is "a surprise to us" that "puts the company in a precarious position," the analyst tells investors. While stating that the company ends this trial in "a relatively stable financial position," the firm says the current risk profile "pushes us to the sidelines," pending visibility on the path forward for repibresib, additional VYN202 data and/or the acquisition of new assets to pursue.
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Valuation Metrics

The current forward P/E ratio for Vyne Therapeutics Inc (VYNE.O) is -0.75, compared to its 5-year average forward P/E of -1.63. For a more detailed relative valuation and DCF analysis to assess Vyne Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.63
Current PE
-0.75
Overvalued PE
-0.64
Undervalued PE
-2.62

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.37
Current EV/EBITDA
0.27
Overvalued EV/EBITDA
0.96
Undervalued EV/EBITDA
-0.22

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
58.89
Current PS
24.91
Overvalued PS
106.67
Undervalued PS
11.11

Financials

AI Analysis
Annual
Quarterly

Whales Holding VYNE

A
Access Industries, Inc.
Holding
VYNE
+69.66%
3M Return

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Frequently Asked Questions

What is Vyne Therapeutics Inc (VYNE) stock price today?

The current price of VYNE is 0.6046 USD — it has decreased -1.63

What is Vyne Therapeutics Inc (VYNE)'s business?

VYNE Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing differentiated therapies to treat chronic inflammatory and immune-mediated conditions with high unmet need. Its lead program is repibresib gel (also known as VYN201), a topically administered, small-molecule pan-BD bromodomain and extra-terminal (BET) inhibitor designed as a soft drug to address diseases involving multiple, diverse inflammatory cell signaling pathways while providing low systemic exposure. Its second program is VYN202, an oral, small-molecule BD2-selective BET inhibitor. The Company has rights to research, develop and commercialize products containing BET inhibitor compounds for the treatment of any disease, disorder or condition in humans. Utilizing its InhiBET platform and through its preclinical and clinical activities, the Company is evaluating the impact that BET inhibitor compounds have on regulating pro-inflammatory cytokines.

What is the price predicton of VYNE Stock?

Wall Street analysts forecast VYNE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for VYNE is2.00 USD with a low forecast of 2.00 USD and a high forecast of 2.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Vyne Therapeutics Inc (VYNE)'s revenue for the last quarter?

Vyne Therapeutics Inc revenue for the last quarter amounts to 130.00K USD, increased 54.76

What is Vyne Therapeutics Inc (VYNE)'s earnings per share (EPS) for the last quarter?

Vyne Therapeutics Inc. EPS for the last quarter amounts to -0.11 USD, decreased -60.71

How many employees does Vyne Therapeutics Inc (VYNE). have?

Vyne Therapeutics Inc (VYNE) has 10 emplpoyees as of March 26 2026.

What is Vyne Therapeutics Inc (VYNE) market cap?

Today VYNE has the market capitalization of 20.15M USD.