LTRN Overview

Clinical Study Results: Lantern Pharma's Phase 1a dose-escalation study of LP-184 demonstrated promising disease control in patients with advanced solid tumors and DNA damage repair deficiencies, meeting all safety and tolerability endpoints.

Future Plans: The company intends to progress LP-184 into multiple Phase 1b/2 trials following the successful outcomes of the initial study.

Clinical Success of LP-284: LP-284, an AI-driven drug candidate, achieved a complete metabolic response in a patient with aggressive B-cell lymphoma after just two cycles, validating its synthetic lethal mechanism and addressing treatment gaps for patients who have failed CAR-T and bispecific therapies.

Strategic Partnership Potential: The drug's profile presents significant partnership opportunities for biopharmaceutical companies, particularly due to its novel mechanism that overcomes resistance to current therapies and demonstrates preclinical synergy with existing FDA-approved agents like rituximab.

Market Need and Economic Impact: With approximately 200,000 new DLBCL cases diagnosed annually and high post-relapse treatment costs, LP-284's off-the-shelf administration could alleviate both clinical and economic burdens in the post-immunotherapy setting.

Ongoing Development and Future Prospects: Lantern Pharma is advancing LP-284 through a Phase 1 trial while exploring combination therapy opportunities, with plans for further clinical assessments and potential expansion into autoimmune and inflammatory conditions.

Company Presentation: Lantern Pharma Inc. will present at the ThinkEquity Conference on October 30, 2025, at 11:30 a.m. ET in New York, NY, with opportunities for one-on-one meetings available throughout the event.

AI-Driven Drug Development: The company utilizes its proprietary AI platform, RADR®, to enhance oncology drug discovery and development, aiming to address significant challenges in the field and potentially impacting over $15 billion in market potential.

Clinical Programs: Lantern Pharma is advancing multiple clinical programs, including a Phase 2 program and several Phase 1 trials, targeting various cancer types with the goal of providing innovative therapies to patients.

Forward-Looking Statements: The press release includes forward-looking statements regarding the company's future performance and drug development plans, highlighting potential risks and uncertainties that could affect outcomes.