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TNYA Should I Buy

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Intellectia

Should You Buy Tenaya Therapeutics Inc (TNYA) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
0.620
1 Day change
-6.77%
52 Week Range
2.350
Analysis Updated At
2026/03/27
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Tenaya Therapeutics Inc (TNYA) is not a good buy for a beginner investor with a long-term focus at this time. The stock demonstrates weak financial performance, bearish technical indicators, insider selling, and lacks positive catalysts or strong signals from proprietary trading tools. Additionally, the analyst's price target reduction and lack of recent news further diminish its attractiveness.

Technical Analysis

The technical indicators for TNYA are bearish. The MACD is negatively expanding (-0.0141), RSI is neutral at 25.742, and moving averages indicate a downtrend (SMA_200 > SMA_20 > SMA_5). The stock is trading below key pivot levels (Pivot: 0.793, current price: 0.7009), with support at 0.705 and resistance at 0.88.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

The options data shows a strong bias towards calls, with a very low put-call ratio. However, this does not align with the weak technical and fundamental outlook.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
10
Buy
4

Positive Catalysts

  • NULL identified. No recent news or significant positive developments.

Neutral/Negative Catalysts

  • Insider selling has increased significantly (55373.56% in the last month).

  • Analysts have lowered the price target from $5 to $2, reflecting diminished confidence.

  • Weak financial performance with declining net income (-15.36% YoY) and EPS (-57.14% YoY).

  • No recent congress trading data or influential figure activity.

Financial Performance

In Q4 2025, the company reported no revenue growth (0% YoY), a net income loss of -$20.175M (-15.36% YoY), and a significant EPS decline (-57.14% YoY). Gross margin remains at 0%. The financials indicate poor growth trends and a lack of profitability.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Morgan Stanley has reduced the price target from $5 to $2 while maintaining an Overweight rating. The analyst notes challenges for small-to-mid cap biotech companies, despite potential long-term industry tailwinds.

Wall Street analysts forecast TNYA stock price to rise
8 Analyst Rating
Wall Street analysts forecast TNYA stock price to rise
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.665
sliders
Low
2
Averages
9.14
High
40
Current: 0.665
sliders
Low
2
Averages
9.14
High
40
Morgan Stanley
Overweight
downgrade
$5 -> $2
AI Analysis
2026-01-08
Reason
Morgan Stanley
Price Target
$5 -> $2
AI Analysis
2026-01-08
downgrade
Overweight
Reason
Morgan Stanley lowered the firm's price target on Tenaya Therapeutics to $2 from $5 and keeps an Overweight rating on the shares. The firm sees a continuation of U.S. small-to-mid cap biotech's outperformance in 2026 as commercial names transition from "capital consumers to producers" and Large Cap Biopharma faces a looming patent cliff, the analyst tells investors in an outlook note for the group.
Canaccord
Buy
downgrade
$6 -> $4
2025-12-18
Reason
Canaccord
Price Target
$6 -> $4
2025-12-18
downgrade
Buy
Reason
Canaccord lowered the firm's price target on Tenaya Therapeutics to $4 from $6 and keeps a Buy rating on the shares. The firm two key updates from the company; the lifting of the clinical hold on the MyPEAK-1 trial of TN-201 by the FDA and the first look at interim data from the RIDGE-1 Ph1B clinical trial of TN-401 for PKP2-associated ARVC.
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