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TLSI Should I Buy

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Intellectia

Should You Buy TriSalus Life Sciences Inc (TLSI) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
2.670
1 Day change
-41.45%
52 Week Range
7.950
Analysis Updated At
2026/04/24
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TriSalus Life Sciences Inc (TLSI) is not a strong buy for a beginner, long-term investor at this time. While the company shows promising revenue growth and a high gross margin, its declining net income, EPS, and lack of strong trading signals or recent positive news make it less compelling. Additionally, analysts have lowered price targets, reflecting tempered expectations. The stock may be worth monitoring for future opportunities, but it does not present a strong case for immediate investment.

Technical Analysis

The MACD is positive and contracting, indicating mild bullish momentum. RSI is at 71.31, in the neutral zone, suggesting no overbought or oversold conditions. Moving averages are converging, showing no clear trend. Key support is at 4.167, and resistance is at 4.77. The stock is trading pre-market at 4.63, near its resistance level.

Positive Catalysts

  • Revenue increased by 59.85% YoY in Q4 2025, and gross margin improved to 86.66%. Analysts maintain positive ratings despite lowering price targets.

Neutral/Negative Catalysts

  • Net income dropped by -10.45% YoY, and EPS declined significantly (-47.50%). Analysts have lowered price targets, reflecting tempered growth expectations. No recent news or significant trading trends from insiders or hedge funds.

Financial Performance

In Q4 2025, revenue increased to $13.2M, up 59.85% YoY, indicating strong top-line growth. However, net income dropped to -$9.75M, and EPS fell to -0.21, showing worsening profitability. Gross margin improved slightly to 86.66%.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts have lowered price targets recently: Northland reduced the target to $8 from $12.50, and Canaccord reduced it to $7 from $12. Both maintain positive ratings (Outperform and Buy, respectively), but expectations are tempered with a more sustainable growth trajectory.

Wall Street analysts forecast TLSI stock price to rise
6 Analyst Rating
Wall Street analysts forecast TLSI stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 4.560
sliders
Low
10
Averages
11.92
High
16
Current: 4.560
sliders
Low
10
Averages
11.92
High
16
Lake Street
Buy
downgrade
$10 -> $8
AI Analysis
2026-05-13
New
Reason
Lake Street
Price Target
$10 -> $8
AI Analysis
2026-05-13
New
downgrade
Buy
Reason
Lake Street lowered the firm's price target on TriSalus Life Sciences to $8 from $10 and keeps a Buy rating on the shares. The firm reduced its 2026 and 2027 revenue and AEBITDA estimates, but expects a sharp return to 30% growth in the second half and thinks this, coupled with new clinical data and product approvals, will support a rebound in shares.
Northland
Carl Byrnes
Outperform
downgrade
$8
2026-03-23
Reason
Northland
Carl Byrnes
Price Target
$8
2026-03-23
downgrade
Outperform
Reason
Northland analyst Carl Byrnes lowered the firm's price target on TriSalus Life Sciences to $8 from $12.50 and keeps an Outperform rating on the shares. The firm is revising its FY26 and FY27 revenue estimates to reflect "a more measured, yet sustainable 30% growth trajectory," says the analyst, who is adjusting the firm's 12-month price target to reflect these assumptions.
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