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RZLT Overview

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0.000(0.000%)Aft-market
ET
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ET
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Intellectia

Loading chart...

High
5.250
Open
4.900
VWAP
5.06
Vol
2.69M
Mkt Cap
484.35M
Low
4.900
Amount
13.61M
EV/EBITDA(TTM)
--
Total Shares
96.29M
EV
350.60M
EV/OCF(TTM)
--
P/S(TTM)
--
Rezolute, Inc. is a late-stage rare disease company, which is focused on improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Its lead clinical asset, Ersodetug (formerly RZ358), is a potential treatment for hypoglycemia caused by multiple forms of hyperinsulinism including congenital HI and tumor HI. Ersodetug is an intravenously administered human monoclonal antibody that binds to a unique site (allosteric) on the insulin receptor in insulin target tissues, such as in the liver, fat, and muscle. Congenital is a rare pediatric genetic disorder characterized by excessive production of insulin by the pancreas. RZ402, which is an oral plasma kallikrein inhibitor (PKI) being developed as a potential therapy for the chronic treatment of diabetic macular edema (DME). DME is a vascular complication of diabetes and a leading cause of blindness. RZ402 is designed to block bradykinin production and its resulting effects on vascular leakage and inflammation.
Show More

Events Timeline

(ET)
2026-06-02
07:30:00
Rezolute Updates on Phase 3 Study Progress of ersodetug
select
2026-05-12 (ET)
2026-05-12
16:20:00
Cash and Investments Decrease to $120.3M
select

News

Newsfilter
8.5
06-04Newsfilter
Rezolute to Present Research Findings at ENDO Conference
  • Presentation Schedule: Rezolute will showcase four presentations at the Endocrine Society Annual Meeting from June 13-16, 2026, including an oral presentation by Dr. Huseyin Demirbilek, focusing on results from the sunRIZE study, highlighting the company's advancements in ultra-rare diseases.
  • Research Findings Overview: The oral presentation will cover the application of Ersodetug in congenital hyperinsulinism, presenting top-line results from a multi-center, randomized, double-blind, placebo-controlled Phase 3 clinical trial, emphasizing the drug's potential in treating refractory hypoglycemia.
  • Clinical Trial Participation: The sunRIZE study enrolled 63 participants across multiple countries to evaluate the efficacy of Ersodetug in patients aged 3 months to 45 years, and although it did not meet primary and key secondary endpoints, significant glycemic improvements were observed during the maintenance dosing phase compared to placebo.
  • FDA Next Steps: Despite the study not meeting all expected metrics, the FDA encouraged Rezolute to submit comprehensive analysis datasets for independent evaluation, indicating a willingness from regulators to consider the potential value of the drug.
NASDAQ.COM
2.0
06-04NASDAQ.COM
ABIVAX and Others See Significant Stock Gains
  • ABIVAX Clinical Trial Success: ABIVAX reported positive results from its Phase 3 ABTECT trial for Obefazimod in ulcerative colitis, achieving primary endpoint of clinical remission at Week 44 with both 25mg and 50mg doses, planning to submit a New Drug Application to the FDA in late Q4 2026, leading to a 24.34% stock increase to $90.15.
  • Cingulate Faces FDA Challenge: Cingulate's stock rose 21.09% to $4.88 despite the FDA's rejection of its ADHD drug CTx-1301 application; however, with nearly $30 million in cash reserves, the company aims to resolve CMC issues and proceed with resubmission while continuing pre-commercial activities.
  • Alpha Tau Partners with Tolmar: Alpha Tau entered a strategic collaboration with Tolmar to develop and commercialize Alpha DaRT for prostate cancer in the U.S., with Tolmar investing $15 million upfront and $20 million equity stake, while Alpha Tau retains manufacturing rights, resulting in an 18.48% stock increase to $10.58.
  • MiniMed Strong Financial Results: MiniMed reported worldwide net sales of $3.102 billion for FY 2026, a 14.2% increase, and expects around 10% organic revenue growth for FY 2027, reflecting strong international market performance and new product launches, with stock rising 15.94% to $14.26.
seekingalpha
6.0
06-03seekingalpha
Rezolute Stock Rises Following Upgrade by Citizens JMP Securities
  • Stock Upgrade Impact: Rezolute (RZLT) traded higher for the third consecutive session on Wednesday after Citizens JMP Securities upgraded its rating from Market Perform to Market Outperform, reflecting a positive market sentiment towards the company's future prospects.
  • Clinical Trial Progress: The company's interim data from the upLIFT Phase 3 study for its lead asset, ersodetug, in tumor hyperinsulinism, released on Tuesday, triggered nearly an 11% stock price increase, showcasing the drug's potential in the rare disease space.
  • FDA Approval Outlook: Analyst Jason Butler noted that the approval pathway for ersodetug in tumor hyperinsulinism could be distinct from the setbacks faced last year in congenital hyperinsulinism, providing confidence for FDA approval with a target price set at $11.
  • Positive Market Reaction: The stock's rise due to favorable clinical data and the analyst's optimistic rating indicates that investors are increasingly confident in the company's potential success in treating rare diseases, likely attracting more investor interest.
CNBC
6.0
06-03CNBC
Wall Street's Latest Ratings Overview
  • DigitalOcean Coverage Initiated: KeyBanc initiates coverage of DigitalOcean with an Overweight rating and a $200 price target, indicating significant room for expansion in the cloud computing market, which could enhance its growth trajectory.
  • Omnicom Growth Outlook: Goldman Sachs rates Omnicom as a Buy, highlighting an 18% free cash flow yield and organic growth in its core business, suggesting it will outperform consensus EBIT and FCF estimates, reflecting strong performance in the advertising sector.
  • SSR Mining Upgrade: RBC upgrades SSR Mining from Sector Perform to Outperform, citing strategic transactions that have reduced jurisdictional risk and exceptional financial liquidity, with cash representing one-third of market cap, indicating robust future growth potential.
  • Apple's Positive Outlook: Goldman Sachs reiterates a Buy rating on Apple, anticipating the announcement of an AI-enhanced Siri at the upcoming Worldwide Developers Conference, which will include several delayed features, showcasing Apple's ongoing innovation in AI technology.
seekingalpha
9.0
06-02seekingalpha
Rezolute Updates Late-Stage Trial Progress for Ersodetug
  • Participant Progress: Rezolute has enrolled 8 patients in its upLIFT Phase 3 study, with 6 achieving the necessary level to measure the trial's primary endpoint, indicating treatment efficacy and laying a foundation for future market potential.
  • Significant Treatment Effects: All 6 participants discontinued intravenous glucose requirements after therapy, demonstrating positive outcomes in addressing hypoglycemia, which may attract increased investor interest.
  • Good Safety Profile: The company reported no safety concerns during the pivotal and extension phases of the study, enhancing confidence in the therapy and potentially accelerating subsequent regulatory approval processes.
  • Data Release Timeline: The upLIFT trial has reached 50% of its enrollment target, with topline data expected to be reported in H2 2026, further advancing the company's strategic positioning in the rare disease treatment space.
seekingalpha
2.0
05-12seekingalpha
Rezolute Reports Q3 Earnings Beat Expectations
  • Earnings Beat: Rezolute reported a Q3 GAAP EPS of -$0.16, beating expectations by $0.02, indicating a slight improvement in financial performance despite remaining in a loss position.
  • Cash Position: As of March 31, 2026, the company had $120.3 million in cash, cash equivalents, and marketable securities, down from $167.9 million as of June 30, 2025, reflecting pressure on the company's financial management.
  • FDA Meeting Feedback: Despite receiving positive feedback from the FDA meeting, the market remains cautious about the prospects of its lead asset, leading analysts to maintain a
Wall Street analysts forecast RZLT stock price to rise
9 Analyst Rating
Wall Street analysts forecast RZLT stock price to rise
5 Buy
4 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
2.00
Averages
6.29
High
20.00
Current: 0.000
sliders
Low
2.00
Averages
6.29
High
20.00
Guggenheim
Debjit Chattopadhyay
Buy
maintain
$6 -> $11
AI Analysis
2026-06-15
Reason
Guggenheim
Debjit Chattopadhyay
Price Target
$6 -> $11
AI Analysis
2026-06-15
maintain
Buy
Reason
Guggenheim analyst Debjit Chattopadhyay raised the firm's price target on Rezolute to $11 from $6 and keeps a Buy rating on the shares, which the analyst is also naming as a "Best Idea (again)," given what the firm sees as the high probability of a positive tumor-induced hypoglycemia readout over the next six months and a potential 175% upside from current levels.
Maxim
Maxim
Buy
maintain
$10 -> $14
2026-06-03
Reason
Maxim
Maxim
Price Target
$10 -> $14
2026-06-03
maintain
Buy
Reason
Maxim raised the firm's price target on Rezolute to $14 from $10 and keeps a Buy rating on the shares. The firm cites the company having announced interim data from the ongoing Phase 3 "upLIFT" for ersodetug in tumor hyperinsulinism while noting that shares are up 16% on the news and continue to steadily rise in value in 2026, up 78% year-to-date, the analyst tells investors in a research note. Maxim believes this trend should continue as the Phase 3 top-line data in tumor HI remains on track for the second half of the year.
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Valuation Metrics

The current forward P/E ratio for Rezolute Inc (RZLT.O) is 0.00, compared to its 5-year average forward P/E of -2.99. For a more detailed relative valuation and DCF analysis to assess Rezolute Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.99
Current PE
0.00
Overvalued PE
-0.56
Undervalued PE
-5.43

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.01
Undervalued EV/EBITDA
-0.02

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
29.00
Current PS
204.36
Overvalued PS
152.61
Undervalued PS
-94.60

Financials

AI Analysis
Annual
Quarterly

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Whales Holding RZLT

A
Affinity Asset Advisors, LLC
Holding
RZLT
+16.45%
3M Return
R
RA Capital Management, L.P.
Holding
RZLT
+15.13%
3M Return

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Frequently Asked Questions

What is Rezolute Inc (RZLT) stock price today?

The current price of RZLT is 5.03 USD — it has increased 2.86

What is Rezolute Inc (RZLT)'s business?

Rezolute, Inc. is a late-stage rare disease company, which is focused on improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Its lead clinical asset, Ersodetug (formerly RZ358), is a potential treatment for hypoglycemia caused by multiple forms of hyperinsulinism including congenital HI and tumor HI. Ersodetug is an intravenously administered human monoclonal antibody that binds to a unique site (allosteric) on the insulin receptor in insulin target tissues, such as in the liver, fat, and muscle. Congenital is a rare pediatric genetic disorder characterized by excessive production of insulin by the pancreas. RZ402, which is an oral plasma kallikrein inhibitor (PKI) being developed as a potential therapy for the chronic treatment of diabetic macular edema (DME). DME is a vascular complication of diabetes and a leading cause of blindness. RZ402 is designed to block bradykinin production and its resulting effects on vascular leakage and inflammation.

What is the price predicton of RZLT Stock?

Wall Street analysts forecast RZLT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for RZLT is6.29 USD with a low forecast of 2.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Rezolute Inc (RZLT)'s revenue for the last quarter?

Rezolute Inc revenue for the last quarter amounts to -17.37M USD, decreased -13.27

What is Rezolute Inc (RZLT)'s earnings per share (EPS) for the last quarter?

Rezolute Inc. EPS for the last quarter amounts to -13735000.00 USD, decreased -21.06

How many employees does Rezolute Inc (RZLT). have?

Rezolute Inc (RZLT) has 71 emplpoyees as of June 25 2026.

What is Rezolute Inc (RZLT) market cap?

Today RZLT has the market capitalization of 484.35M USD.