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RZLT Overview

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$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
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ET
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Intellectia

Loading chart...

High
4.540
Open
4.375
VWAP
4.29
Vol
2.84M
Mkt Cap
385.17M
Low
4.080
Amount
12.16M
EV/EBITDA(TTM)
--
Total Shares
96.29M
EV
264.90M
EV/OCF(TTM)
--
P/S(TTM)
--
Rezolute, Inc. is a late-stage rare disease company, which is focused on improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Its lead clinical asset, Ersodetug (formerly RZ358), is a potential treatment for hypoglycemia caused by multiple forms of hyperinsulinism including congenital HI and tumor HI. Ersodetug is an intravenously administered human monoclonal antibody that binds to a unique site (allosteric) on the insulin receptor in insulin target tissues, such as in the liver, fat, and muscle. Congenital is a rare pediatric genetic disorder characterized by excessive production of insulin by the pancreas. RZ402, which is an oral plasma kallikrein inhibitor (PKI) being developed as a potential therapy for the chronic treatment of diabetic macular edema (DME). DME is a vascular complication of diabetes and a leading cause of blindness. RZ402 is designed to block bradykinin production and its resulting effects on vascular leakage and inflammation.
Show More

Events Timeline

(ET)
2026-06-02
07:30:00
Rezolute Updates on Phase 3 Study Progress of ersodetug
select
2026-05-12 (ET)
2026-05-12
16:20:00
Cash and Investments Decrease to $120.3M
select
2026-05-01 (ET)
2026-05-01
12:20:00
Rezolute Presents ersodetug Study Results at Pediatric Endocrine Society Annual Meeting
select

News

seekingalpha
6.0
16:11 PMseekingalpha
Rezolute Stock Rises Following Upgrade by Citizens JMP Securities
  • Stock Upgrade Impact: Rezolute (RZLT) traded higher for the third consecutive session on Wednesday after Citizens JMP Securities upgraded its rating from Market Perform to Market Outperform, reflecting a positive market sentiment towards the company's future prospects.
  • Clinical Trial Progress: The company's interim data from the upLIFT Phase 3 study for its lead asset, ersodetug, in tumor hyperinsulinism, released on Tuesday, triggered nearly an 11% stock price increase, showcasing the drug's potential in the rare disease space.
  • FDA Approval Outlook: Analyst Jason Butler noted that the approval pathway for ersodetug in tumor hyperinsulinism could be distinct from the setbacks faced last year in congenital hyperinsulinism, providing confidence for FDA approval with a target price set at $11.
  • Positive Market Reaction: The stock's rise due to favorable clinical data and the analyst's optimistic rating indicates that investors are increasingly confident in the company's potential success in treating rare diseases, likely attracting more investor interest.
CNBC
6.0
13:03 PMCNBC
Wall Street's Latest Ratings Overview
  • DigitalOcean Coverage Initiated: KeyBanc initiates coverage of DigitalOcean with an Overweight rating and a $200 price target, indicating significant room for expansion in the cloud computing market, which could enhance its growth trajectory.
  • Omnicom Growth Outlook: Goldman Sachs rates Omnicom as a Buy, highlighting an 18% free cash flow yield and organic growth in its core business, suggesting it will outperform consensus EBIT and FCF estimates, reflecting strong performance in the advertising sector.
  • SSR Mining Upgrade: RBC upgrades SSR Mining from Sector Perform to Outperform, citing strategic transactions that have reduced jurisdictional risk and exceptional financial liquidity, with cash representing one-third of market cap, indicating robust future growth potential.
  • Apple's Positive Outlook: Goldman Sachs reiterates a Buy rating on Apple, anticipating the announcement of an AI-enhanced Siri at the upcoming Worldwide Developers Conference, which will include several delayed features, showcasing Apple's ongoing innovation in AI technology.
seekingalpha
9.0
06-02seekingalpha
Rezolute Updates Late-Stage Trial Progress for Ersodetug
  • Participant Progress: Rezolute has enrolled 8 patients in its upLIFT Phase 3 study, with 6 achieving the necessary level to measure the trial's primary endpoint, indicating treatment efficacy and laying a foundation for future market potential.
  • Significant Treatment Effects: All 6 participants discontinued intravenous glucose requirements after therapy, demonstrating positive outcomes in addressing hypoglycemia, which may attract increased investor interest.
  • Good Safety Profile: The company reported no safety concerns during the pivotal and extension phases of the study, enhancing confidence in the therapy and potentially accelerating subsequent regulatory approval processes.
  • Data Release Timeline: The upLIFT trial has reached 50% of its enrollment target, with topline data expected to be reported in H2 2026, further advancing the company's strategic positioning in the rare disease treatment space.
seekingalpha
2.0
05-12seekingalpha
Rezolute Reports Q3 Earnings Beat Expectations
  • Earnings Beat: Rezolute reported a Q3 GAAP EPS of -$0.16, beating expectations by $0.02, indicating a slight improvement in financial performance despite remaining in a loss position.
  • Cash Position: As of March 31, 2026, the company had $120.3 million in cash, cash equivalents, and marketable securities, down from $167.9 million as of June 30, 2025, reflecting pressure on the company's financial management.
  • FDA Meeting Feedback: Despite receiving positive feedback from the FDA meeting, the market remains cautious about the prospects of its lead asset, leading analysts to maintain a
Newsfilter
2.0
05-01Newsfilter
Rezolute Presents New Data on Ersodetug Study Outcomes
  • Glycemic Control Improvement: In the sunRIZE study, the ersodetug treatment group showed clinically relevant reductions of over 50% in average daily time in hypoglycemia, while the placebo group did not achieve statistical significance, indicating the drug's potential in improving glycemic control.
  • Strong Treatment Continuity: During the open-label extension phase, all 59 participants opted to continue receiving ersodetug, with 57 attending regular study visits, demonstrating good tolerability and sustained efficacy of the drug in long-term use.
  • Reduction in Background Therapy: The use of ersodetug has led to a significant decrease in standard treatments (e.g., diazoxide, somatostatin analogs) for many patients, showcasing the drug's effectiveness as a monotherapy.
  • Positive FDA Interaction: Rezolute's meeting with the FDA acknowledged challenges with the study's primary endpoint and requested broader data submission for further evaluation, reflecting the company's confidence and efforts toward obtaining approval.
Newsfilter
9.0
03-25Newsfilter
Rezolute's Positive FDA Meeting Outcomes for sunRIZE Program
  • FDA Meeting Outcomes: Rezolute's March 17, 2026 meeting with the FDA yielded positive feedback, as the agency did not outright dismiss the sunRIZE study despite it not meeting its primary endpoint, indicating interest in further review.
  • Clinical Data Insights: The company presented summary results from the sunRIZE study, highlighting that behavioral factors may have confounded the primary endpoint's statistical significance, while significant improvements in time in hypoglycemia were observed via CGM monitoring, suggesting potential drug efficacy.
  • Next Steps Encouraged: The FDA urged Rezolute to submit study reports and analysis datasets for independent evaluation, which could pave the way for a marketing application for sunRIZE, reflecting the agency's cautious approach to new therapies.
  • Patient Needs Emphasized: During the meeting, the FDA and Rezolute discussed the profound impact of congenital hyperinsulinism on patients, underscoring the necessity for new treatment options and reflecting a shared commitment to improving patient care.
Wall Street analysts forecast RZLT stock price to rise
9 Analyst Rating
Wall Street analysts forecast RZLT stock price to rise
5 Buy
4 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
2.00
Averages
6.29
High
20.00
Current: 0.000
sliders
Low
2.00
Averages
6.29
High
20.00
Maxim
Maxim
Buy
maintain
$10 -> $14
AI Analysis
2026-06-03
New
Reason
Maxim
Maxim
Price Target
$10 -> $14
AI Analysis
2026-06-03
New
maintain
Buy
Reason
Maxim raised the firm's price target on Rezolute to $14 from $10 and keeps a Buy rating on the shares. The firm cites the company having announced interim data from the ongoing Phase 3 "upLIFT" for ersodetug in tumor hyperinsulinism while noting that shares are up 16% on the news and continue to steadily rise in value in 2026, up 78% year-to-date, the analyst tells investors in a research note. Maxim believes this trend should continue as the Phase 3 top-line data in tumor HI remains on track for the second half of the year.
Wedbush
Yun Zhong
Outperform
maintain
$5 -> $6
2026-06-03
New
Reason
Wedbush
Yun Zhong
Price Target
$5 -> $6
2026-06-03
New
maintain
Outperform
Reason
Wedbush analyst Yun Zhong raised the firm's price target on Rezolute to $6 from $5 and keeps an Outperform rating on the shares. The interim data that Rezolute reported from the ongoing open-label Phase 3 upLIFT study of ersodetug in patients with tumor hyperinsulinism, from eight patients that have been enrolled to date, essentially showed that every single patient that completed the eight-week pivotal treatment period qualified as a responder, the firm notes. According to Wedbush's follow-up discussion with management, the study size remains unchanged at 16 patients, and top-line data readout remains on track for the second half of 2026. Based on the positive data, which the firm believes should support a higher likelihood of success for ersodetug in tumor HI, Wedbush has increased its probability of success projection for the program from 40% to 70%.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for RZLT
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Valuation Metrics

The current forward P/E ratio for Rezolute Inc (RZLT.O) is 0.00, compared to its 5-year average forward P/E of -3.01. For a more detailed relative valuation and DCF analysis to assess Rezolute Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.01
Current PE
0.00
Overvalued PE
-0.59
Undervalued PE
-5.42

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.01
Undervalued EV/EBITDA
-0.02

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
26.68
Current PS
135.04
Overvalued PS
149.08
Undervalued PS
-95.72

Financials

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Whales Holding RZLT

A
Affinity Asset Advisors, LLC
Holding
RZLT
-2.32%
3M Return
R
RA Capital Management, L.P.
Holding
RZLT
-6.41%
3M Return

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Frequently Asked Questions

What is Rezolute Inc (RZLT) stock price today?

The current price of RZLT is 4.235 USD — it has increased 5.88

What is Rezolute Inc (RZLT)'s business?

Rezolute, Inc. is a late-stage rare disease company, which is focused on improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Its lead clinical asset, Ersodetug (formerly RZ358), is a potential treatment for hypoglycemia caused by multiple forms of hyperinsulinism including congenital HI and tumor HI. Ersodetug is an intravenously administered human monoclonal antibody that binds to a unique site (allosteric) on the insulin receptor in insulin target tissues, such as in the liver, fat, and muscle. Congenital is a rare pediatric genetic disorder characterized by excessive production of insulin by the pancreas. RZ402, which is an oral plasma kallikrein inhibitor (PKI) being developed as a potential therapy for the chronic treatment of diabetic macular edema (DME). DME is a vascular complication of diabetes and a leading cause of blindness. RZ402 is designed to block bradykinin production and its resulting effects on vascular leakage and inflammation.

What is the price predicton of RZLT Stock?

Wall Street analysts forecast RZLT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for RZLT is6.29 USD with a low forecast of 2.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Rezolute Inc (RZLT)'s revenue for the last quarter?

Rezolute Inc revenue for the last quarter amounts to -17.37M USD, decreased -13.27

What is Rezolute Inc (RZLT)'s earnings per share (EPS) for the last quarter?

Rezolute Inc. EPS for the last quarter amounts to -13735000.00 USD, decreased -21.06

How many employees does Rezolute Inc (RZLT). have?

Rezolute Inc (RZLT) has 71 emplpoyees as of June 03 2026.

What is Rezolute Inc (RZLT) market cap?

Today RZLT has the market capitalization of 385.17M USD.