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RARE Should I Buy

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Intellectia

Should You Buy Ultragenyx Pharmaceutical Inc (RARE) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
26.120
1 Day change
-0.04%
52 Week Range
42.370
Analysis Updated At
2026/04/24
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Ultragenyx Pharmaceutical Inc (RARE) is not a strong buy at this moment for a beginner investor with a long-term strategy. The stock lacks immediate positive catalysts, has mixed analyst sentiment, and its financial performance shows declining profitability metrics despite revenue growth. The technical indicators and options data suggest a neutral to slightly bearish sentiment, making it prudent to hold off on investing until clearer signals or catalysts emerge.

Technical Analysis

The MACD is positive but contracting, indicating weakening bullish momentum. RSI is neutral at 53.509, suggesting no clear overbought or oversold conditions. Moving averages are converging, showing no strong directional trend. The stock is trading near its pivot level of 24.535, with key resistance at 25.75 and support at 23.321.

Options Data

Bullish
Open Interest Put-Call Ratio
Bearish
Option Volume Put-Call Ratio

The put-call ratios indicate a slightly bearish sentiment in the options market. Implied volatility is low at 39.42, with an IV percentile of 3.98, suggesting limited expectations for significant price movement.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
4
Buy
7

Positive Catalysts

  • Analyst Morgan Stanley sees a favorable asymmetric setup with 50%-70% upside potential for GTX-102 Phase 3 data in 2026.

Neutral/Negative Catalysts

  • Lack of recent news or significant trading trends from hedge funds, insiders, or Congress.

Financial Performance

In Q4 2025, revenue increased to $207.28M, up 25.72% YoY. However, net income dropped to -$128.56M, down -3.62% YoY. EPS also declined to -1.29, down -7.19% YoY. Gross margin decreased to 85.84%, down -4.36% YoY, reflecting challenges in profitability.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analyst sentiment is mixed. Morgan Stanley raised its price target to $67, citing potential upside from GTX-102 Phase 3 data. However, Goldman Sachs downgraded the stock to Neutral with a price target of $25 due to risks in clinical trial design and disease heterogeneity. Other analysts have lowered price targets but maintain Buy or Outperform ratings, indicating cautious optimism.

Wall Street analysts forecast RARE stock price to rise
18 Analyst Rating
Wall Street analysts forecast RARE stock price to rise
17 Buy
1 Hold
0 Sell
Strong Buy
Current: 26.130
sliders
Low
35
Averages
61.65
High
120
Current: 26.130
sliders
Low
35
Averages
61.65
High
120
Wedbush
Neutral
to
Neutral
downgrade
$27 -> $26
AI Analysis
2026-05-08
New
Reason
Wedbush
Price Target
$27 -> $26
AI Analysis
2026-05-08
New
downgrade
Neutral
to
Neutral
Reason
Wedbush lowered the firm's price target on Ultragenyx to $26 from $27 and keeps a Neutral rating on the shares. While the top-line miss is disappointing, the firm looks for Crysvita to course-correct over the remainder of the year as management reiterated all elements of FY26 revenue guidance. Additionally, they continue to anticipate reaching profitability in 2027. Most important in the near-term, Wedbush awaits Phase 3 ASPIRE data for GTX102, while Ultragenyx holds two PDUFAs for DTX401 and UX111 with both providing an opportunity for monetizable PRVs.
Guggenheim
Buy
downgrade
$52 -> $43
2026-05-08
New
Reason
Guggenheim
Price Target
$52 -> $43
2026-05-08
New
downgrade
Buy
Reason
Guggenheim lowered the firm's price target on Ultragenyx to $43 from $52 and keeps a Buy rating on the shares. The firm lowered its target to reflect challenges with ASPIRE Phase 3 with enrollment restricted to deletion patients between the ages of 4 and 17.
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