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OGEN Overview

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0.000
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Intellectia

Loading chart...

High
0.590
Open
0.587
VWAP
0.55
Vol
76.03K
Mkt Cap
2.30M
Low
0.521
Amount
41.61K
EV/EBITDA(TTM)
--
Total Shares
4.34M
EV
-5.87M
EV/OCF(TTM)
--
P/S(TTM)
--
Oragenics, Inc. is a development-stage company. It is engaged in the research and development of nasal delivery pharmaceutical medications in neurology and fighting infectious diseases. It focuses on nasal delivery of pharmaceutical medications in neurology and fighting infectious diseases, including drug candidates for treating mild traumatic brain injury (mTBI or Concussion), and for treating Niemann Pick Disease Type C (NPC), and proprietary powder formulation and an intranasal delivery device. Its lead product, ONP-002, is a fully synthetic, non-naturally occurring neurosteroid, is lipophilic, and can cross the blood-brain barrier to rapidly reduce swelling, oxidative stress and inflammation while restoring proper blood flow through gene amplification. It is also focused on developing medical products that treat brain related illnesses and diseases (the Neurology Assets). Its other product candidate, ONP-001, is in its early stage and clinical trials.
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Events Timeline

(ET)
2026-03-25
18:40:00
Oragenics Announces Audit Opinion Regarding Going Concern
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2026-03-17 (ET)
2026-03-17
08:50:00
Oragenics Files Annual Report on Form 10-K for Fiscal Year 2025
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2026-03-12 (ET)
2026-03-12
08:50:00
Oragenics Completes First Site Initiation Visit for ONP-002 Phase IIa Trial
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2026-03-11 (ET)
2026-03-11
08:40:00
Oragenics Explores Acquisition of CNS Assets
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2026-03-10 (ET)
2026-03-10
08:40:00
Oragenics Receives HREC Approval for ONP-002 Clinical Trial in Australia
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2026-02-09 (ET)
2026-02-09
08:50:00
Oragenics Sets 2026 Goals: Advancing ONP-002 Clinical Trials
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2026-02-03 (ET)
2026-02-03
08:40:00
Oragenics Partners with Duck Flats Pharma to Advance New Drug Development
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2026-01-22 (ET)
2026-01-22
16:20:00
Oragenics Files $100M Mixed Securities Shelf
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2025-10-21 (ET)
2025-10-21
08:14:41
Oragenics Meets NYSE Compliance Requirements Again
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2025-10-07 (ET)
2025-10-07
09:17:53
Oragenics and Receptor.AI Collaborate to Speed Up Pipeline Development
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News

Newsfilter
9.5
03-25Newsfilter
Oragenics Releases Audit Opinion on Going Concern
  • Audit Opinion Disclosure: Oragenics disclosed in its 2025 Annual Report that its independent auditor provided an unqualified opinion on its financial statements, yet included an explanatory paragraph regarding the company's ability to continue as a going concern, indicating financial uncertainty that may impact investor confidence.
  • Financial Reporting Compliance: This announcement complies with NYSE American LLC Company Guide Section 610(b), emphasizing the company's commitment to financial transparency, even though there were no changes to the financial statements or the Annual Report.
  • Clinical Development Progress: Oragenics' lead candidate, ONP-002, is in Phase IIa clinical development aimed at treating concussions and mild traumatic brain injuries affecting approximately 69 million people annually, showcasing the company's potential in the neuropharmaceutical sector.
  • Future Outlook: The company is exploring ways to broaden its CNS pipeline strategy through both internal development and strategic business development, demonstrating a commitment to innovation and market expansion despite facing financial challenges.
Newsfilter
9.0
03-10Newsfilter
Oragenics Secures Clinical Trial Approval in Australia
  • Clinical Trial Approval: Oragenics has received final approval from the Human Research Ethics Committee in Australia to commence its Phase IIa clinical trial for ONP-002, targeting mild traumatic brain injury (mTBI), marking a significant advancement in developing the first pharmacological treatment for brain injuries.
  • Significant Market Potential: The global market for mild traumatic brain injuries is projected to exceed $9 billion by 2030, and if approved by the FDA, ONP-002 would become the first pharmacological standard of care, addressing the needs of millions of patients currently without effective treatment options.
  • Innovative Drug Mechanism: ONP-002 is designed as a first-in-class neurosteroid that targets the underlying biological mechanisms of brain injury by reducing neuroinflammation and oxidative stress, representing a potential paradigm shift from mere symptom management to active neurological intervention.
  • Rigorous Trial Design: The Phase IIa clinical trial will enroll 40 patients to assess the drug's safety and tolerability, with data readout expected by the end of 2026; successful results will support further investigational new drug applications in the U.S.
Newsfilter
9.0
02-09Newsfilter
Oragenics Advances ONP-002 Clinical Trials for Concussion Treatment
  • Clinical Trial Readiness: Oragenics has completed preparations for clinical trial sites in Australia, with the first patient dosing for ONP-002 expected to commence in 2026, marking a significant advancement in the field of brain therapeutics and potentially becoming the first pharmacological treatment for concussions.
  • Significant Market Potential: The unique intranasal delivery system of ONP-002 is designed to rapidly deliver medication to the brain, targeting the approximately 1.7 to 3.8 million Americans who suffer from traumatic brain injuries annually, and if approved, it will enter a global concussion market projected to reach $9 billion by 2030.
  • Strong Financial Backing: The company raised $16.5 million through the issuance of Series H convertible preferred stock and warrants, ensuring funding for the clinical development and operations of ONP-002, while a clean balance sheet with zero debt provides ample runway for future trials.
  • Strategic Partnerships and Innovation: Oragenics has formed a strategic collaboration with Receptor.AI to leverage artificial intelligence for optimizing drug discovery, which may facilitate the expansion of its molecular portfolio and enhance the company's competitive edge in the neuroscience sector.
Newsfilter
8.5
02-03Newsfilter
Oragenics Partners with DUCK FLATS Pharma to Advance Novel Concussion Therapy
  • Collaboration Enhances Regulatory Readiness: Oragenics partners with DUCK FLATS Pharma to support FDA application and clinical trial design for its novel intranasal concussion therapy, aiming to reduce risks and ensure trial integrity in the U.S. development pathway.
  • Significant Market Potential: The global concussion market is projected to exceed $9 billion by 2027, and if approved, ONP-002 will enter a nasal drug delivery market expected to surpass $125 billion, highlighting substantial commercial opportunities.
  • Clinical Trial Progress: Oragenics is advancing ONP-002 through Phase 2a clinical trials in Australia, with plans for subsequent Phase 2b trials in the U.S., marking a strategic move in the treatment of neurological disorders.
  • Rich Industry Experience: DUCK FLATS Pharma brings approximately 38 years of regulatory and drug development experience, having managed over 400 regulatory documents, which is expected to provide Oragenics with valuable insights to excel in a competitive market.
Newsfilter
8.5
02-02Newsfilter
Oragenics Engages with Global Clinical Research Leaders at SCOPE Summit
  • Clinical Trial Progress: Oragenics is advancing its first-in-class concussion treatment candidate ONP-002, with plans to initiate Phase 2a clinical trials in Australia, aiming to address significant unmet medical needs in this area, particularly as there are currently no FDA-approved therapies.
  • Global Conference Participation: The company will engage with experts from over 1,200 companies across 30 countries at the 2026 SCOPE Summit, leveraging this opportunity to gain insights into cutting-edge technological innovations and best practices in clinical operations.
  • Technological Platform Advantage: Oragenics' proprietary intranasal delivery platform enables targeted, non-invasive delivery of therapeutics directly to the brain, which is expected to positively impact various neurological conditions, including Parkinson's disease and Alzheimer's disease.
  • Future Development Plans: In addition to the Phase 2a trials in Australia, Oragenics plans to conduct Phase 2b trials in the U.S., further advancing the development of ONP-002 and demonstrating the company's long-term commitment to neurological care.
Benzinga
8.5
01-22Benzinga
High Roller Technologies Inc Closes Direct Offering, Raises $25 Million
  • Successful Financing: High Roller Technologies Inc announced the completion of a registered direct offering of 1.89 million common shares at $13.21 per share, raising approximately $25 million in gross proceeds, significantly enhancing the company's liquidity to support future business expansion.
  • Stock Surge: Following this announcement, High Roller’s shares jumped 29.6% to $10.21 in pre-market trading, reflecting strong market confidence in the company's growth potential and likely attracting more investor interest.
  • Positive Market Reaction: The successful financing not only improves High Roller’s capital structure but also positions the company to gain a stronger competitive edge in the fiercely competitive online gaming market, aiding in further market share expansion.
  • Strategic Growth Outlook: With this financing, High Roller Technologies can accelerate its strategic plans, including technological innovation and market expansion, which is expected to bring long-term growth opportunities and enhance shareholder value.

Valuation Metrics

The current forward P/E ratio for Oragenics Inc (OGEN.A) is -1.10, compared to its 5-year average forward P/E of -1.14. For a more detailed relative valuation and DCF analysis to assess Oragenics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.14
Current PE
-1.10
Overvalued PE
0.15
Undervalued PE
-2.42

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.01
Current EV/EBITDA
0.57
Overvalued EV/EBITDA
0.14
Undervalued EV/EBITDA
-0.15

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
25.08
Current PS
0.00
Overvalued PS
132.54
Undervalued PS
-82.38

Financials

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Frequently Asked Questions

What is Oragenics Inc (OGEN) stock price today?

The current price of OGEN is 0.53 USD — it has decreased -8.3

What is Oragenics Inc (OGEN)'s business?

Oragenics, Inc. is a development-stage company. It is engaged in the research and development of nasal delivery pharmaceutical medications in neurology and fighting infectious diseases. It focuses on nasal delivery of pharmaceutical medications in neurology and fighting infectious diseases, including drug candidates for treating mild traumatic brain injury (mTBI or Concussion), and for treating Niemann Pick Disease Type C (NPC), and proprietary powder formulation and an intranasal delivery device. Its lead product, ONP-002, is a fully synthetic, non-naturally occurring neurosteroid, is lipophilic, and can cross the blood-brain barrier to rapidly reduce swelling, oxidative stress and inflammation while restoring proper blood flow through gene amplification. It is also focused on developing medical products that treat brain related illnesses and diseases (the Neurology Assets). Its other product candidate, ONP-001, is in its early stage and clinical trials.

What is the price predicton of OGEN Stock?

Wall Street analysts forecast OGEN stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for OGEN is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Oragenics Inc (OGEN)'s revenue for the last quarter?

Oragenics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Oragenics Inc (OGEN)'s earnings per share (EPS) for the last quarter?

Oragenics Inc. EPS for the last quarter amounts to -0.54 USD, decreased -93.59

How many employees does Oragenics Inc (OGEN). have?

Oragenics Inc (OGEN) has 3 emplpoyees as of March 31 2026.

What is Oragenics Inc (OGEN) market cap?

Today OGEN has the market capitalization of 2.30M USD.