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MPLT Overview

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ET
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0.000
0.000(0.000%)
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ET
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Intellectia

Loading chart...

High
19.250
Open
18.640
VWAP
18.28
Vol
278.10K
Mkt Cap
857.10M
Low
17.720
Amount
5.08M
EV/EBITDA(TTM)
--
Total Shares
45.37M
EV
1.10B
EV/OCF(TTM)
--
P/S(TTM)
--
MapLight Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on improving the lives of patients suffering from debilitating central nervous system disorders (CNS). Its lead product candidate, ML-007C-MA, is a fixed-dose combination of an M1/M4 muscarinic agonist, ML-007, co-formulated with a peripherally acting anticholinergic (PAC), which it is initially developing for the treatment of schizophrenia and Alzheimer’s disease psychosis (ADP). ML-007C-MA is designed to activate both M1 and M4 muscarinic receptors in the CNS to drive efficacy, while synchronizing the pharmacokinetics of the agonist and antagonist components to mitigate peripheral cholinergic side effects. Its second product candidate, ML-004, is a 5-HT1B/1D agonist that the Company is developing for the treatment of social communication deficit and/or irritability in autism spectrum disorder. It is also advancing two preclinical programs, ML-021 and ML-009.
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Events Timeline

(ET)
2026-01-09
07:10:00
MapLight Therapeutics Updates Timing for ZEPHYR and IRIS Clinical Study Results
select
2026-01-05 (ET)
2026-01-05
07:10:00
MapLight Receives FDA Fast Track Designation for ML-007C-MA
select
2025-12-16 (ET)
2025-12-16
07:10:00
SandboxAQ and MapLight Enter Strategic Collaboration with Potential Payments Up to $200M
select
2025-10-27 (ET)
2025-10-27
12:00:19
MapLight Therapeutics Debuts at $19 After IPO Set at $17 per Share
select

News

NASDAQ.COM
5.0
02-23NASDAQ.COM
Maplight and CVRx Executives Increase Stock Holdings
  • Maplight Purchase: George Pavlov of Maplight Therapeutics made a $441,168 purchase of 25,000 shares of MPLT at $17.65 each on Friday, marking his first buy in the past twelve months, indicating confidence in the company's future prospects.
  • Market Performance: On Monday, Maplight Therapeutics' stock traded down approximately 1.4%, and while Pavlov's purchase may not have immediately boosted the stock price, his long-term investment intentions could influence market sentiment.
  • CVRx Purchase: Mudit K. Jain also bought $297,592 worth of CVRx, acquiring 46,800 shares at $6.36 each on Friday, which is his third purchase in the past twelve months, reflecting his ongoing optimism about CVRx.
  • Stock Fluctuation: CVRx's stock rose about 12.1% on Monday, reaching a high of $7.22, with Jain's investment up approximately 13.5% at the peak, showcasing a positive market reaction to CVRx.
renaissancecapital
8.5
01-09renaissancecapital
Aktis Oncology Launches $200 Million IPO with $100 Million Investment from Eli Lilly
  • IPO Market Recovery: Aktis Oncology launched a $200 million IPO on Monday, indicating a resurgence in the biotech IPO market after a period of uneven performance, and is set to be the first significant IPO of 2026.
  • Increased Financing Size: Just two days after the IPO launch, Aktis upsized the deal by 50%, which not only reflects growing investor confidence in its prospects but also indicates a rising interest in the biotech sector.
  • Strategic Partnership Support: Aktis disclosed a $100 million investment from partner Eli Lilly, which will provide robust support for the company's R&D and market expansion, further strengthening its position in the competitive biotech landscape.
  • Optimistic Market Outlook: As the first major biotech IPO of 2026, Aktis's success could attract more investor attention to the biotech sector, potentially driving recovery and growth across the industry.
Globenewswire
9.0
01-09Globenewswire
MapLight Accelerates Phase 2 Trial Timelines for Schizophrenia and Autism Studies
  • Clinical Trial Progress: MapLight Therapeutics' ZEPHYR trial is accelerating enrollment, with topline results for 300 schizophrenia patients now expected in Q3 2026, showcasing the company's efficient execution under high-quality standards.
  • IRIS Trial Update: The IRIS trial has completed enrollment, with topline results for approximately 160 autism patients also anticipated in Q3 2026, further enhancing the company's research capabilities in central nervous system disorders.
  • Strategic Commitment: CEO Chris Kroeger emphasized that the rapid enrollment pace not only narrows timing guidance but also demonstrates the company's commitment to advancing its programs, potentially boosting investor confidence and attracting more funding support.
  • Market Potential: With a focus on developing drugs for mental health disorders, MapLight is positioned to fill the market gap for specific therapies as clinical trials progress, driving future business growth.
NASDAQ.COM
9.0
01-05NASDAQ.COM
MapLight Therapeutics Receives FDA Fast Track Designation for ML-007C-MA in Alzheimer's Treatment
  • Fast Track Designation: MapLight Therapeutics' ML-007C-MA has received FDA Fast Track designation, enabling more frequent interactions with the FDA, which may accelerate drug development and increase the likelihood of priority review.
  • Clinical Trial Progress: In a Phase 1 study, ML-007C-MA demonstrated a favorable safety and tolerability profile in healthy elderly participants, with enrollment ongoing in the Phase 2 VISTA study, and topline results expected in the second half of 2027.
  • Market Reaction: Despite the FDA designation, MapLight Therapeutics shares closed at $16.77 on Friday, down 4.5%, indicating cautious market sentiment regarding the drug's development progress.
  • Strategic Implications: This designation not only enhances the market potential of ML-007C-MA but also supports the company's competitive position in the Alzheimer's treatment space, particularly in addressing unmet medical needs for patients.
Globenewswire
9.0
01-05Globenewswire
MapLight Receives FDA Fast Track Designation for ML-007C-MA in Alzheimer's Disease Psychosis
  • Fast Track Designation: MapLight Therapeutics announced that its investigational drug ML-007C-MA has received FDA Fast Track designation for treating hallucinations and delusions associated with Alzheimer's disease psychosis, marking a significant milestone in addressing unmet medical needs.
  • Clinical Trial Progress: ML-007C-MA demonstrated a favorable safety and tolerability profile in a Phase 1 trial and is currently undergoing a Phase 2 VISTA study, aiming to enroll 300 participants and report topline results in the second half of 2027, further advancing drug development.
  • Market Demand: Alzheimer's disease psychosis affects approximately 40% of patients, with symptom occurrence increasing as the disease progresses; the development of ML-007C-MA could significantly improve the quality of life for this population and fill a critical market gap.
  • Strategic Implications: This FDA designation not only enhances MapLight's competitiveness in the CNS field but may also expedite the drug's market entry, potentially leading to increased economic returns and market share growth for the company.
Newsfilter
9.0
01-05Newsfilter
MapLight Receives FDA Fast Track Designation for ML-007C-MA in Alzheimer's Disease Psychosis
  • Fast Track Designation: MapLight Therapeutics' ML-007C-MA has received FDA Fast Track designation for treating hallucinations and delusions associated with Alzheimer's disease psychosis, marking a significant milestone in addressing unmet medical needs.
  • Clinical Trial Progress: The Phase 1 trial of ML-007C-MA demonstrated a favorable safety and tolerability profile in healthy elderly participants, with the ongoing Phase 2 VISTA study aiming to enroll 300 participants and report topline results in the second half of 2027.
  • Market Potential: Alzheimer's disease psychosis affects approximately 40% of patients, with increasing symptom incidence as the disease progresses, and the development of ML-007C-MA could significantly improve patient quality of life and slow cognitive decline.
  • Strategic Implications: This FDA designation not only accelerates the drug development process but may also provide MapLight with more frequent interactions with the FDA, thereby expediting the approval process and enhancing the company's competitiveness in the biopharmaceutical sector.
Wall Street analysts forecast MPLT stock price to rise
4 Analyst Rating
Wall Street analysts forecast MPLT stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
28.00
Averages
31.00
High
34.00
Current: 0.000
sliders
Low
28.00
Averages
31.00
High
34.00
Stifel
Paul Matteis
Buy
maintain
$28
AI Analysis
2025-12-03
Reason
Stifel
Paul Matteis
Price Target
$28
AI Analysis
2025-12-03
maintain
Buy
Reason
After Bristol Myers (BMY) announced this morning that the ADEPT-2 study of Cobenfy in in Alzheimer's disease psychosis will continue enrolling additional patients after a review identified irregularities due to trial conduct at some sites, Stifel analyst Paul Matteis contends that the study continuation has "grey implications, but at face is a win" for MapLight Therapeutics (MPLT) and overall this is a positive, though there are some lingering questions. For MapLight, the firm thinks there's a chance that their muscarinic drug has a wider therapeutic index in elderly subjects and the firm sees "an upside risk/reward" as the current valuation "arguably prices in very little ADP credit." Stifel has a Buy rating and $28 price target on MapLight shares, which are up $3.61, or 28%, to $16.50 in morning trading.
Leerink
Marc Goodman
Outperform
initiated
$30
2025-11-21
Reason
Leerink
Marc Goodman
Price Target
$30
2025-11-21
initiated
Outperform
Reason
Leerink analyst Marc Goodman initiated coverage of MapLight Therapeutics with an Outperform rating and $30 price target. The firm is bullish on the muscarinic space and says MapLight's lead asset ML-007C-MA has a potentially better clinical profile than Cobenfy. ML-007C-MA is in Phase 2 development for the treatment of Alzheimer's disease psychosis, which is a large market with significant unmet need, the analyst tells investors in a research note.
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Valuation Metrics

The current forward P/E ratio for MapLight Therapeutics Inc (MPLT.O) is -4.48, compared to its 5-year average forward P/E of -4.45. For a more detailed relative valuation and DCF analysis to assess MapLight Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.45
Current PE
-4.48
Overvalued PE
-3.80
Undervalued PE
-5.10

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.14
Current EV/EBITDA
-5.24
Overvalued EV/EBITDA
-4.53
Undervalued EV/EBITDA
-5.76

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

Whales Holding MPLT

N
Novo Holdings A/S
Holding
MPLT
-18.90%
3M Return

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Frequently Asked Questions

What is MapLight Therapeutics Inc (MPLT) stock price today?

The current price of MPLT is 17.87 USD — it has decreased -5.4

What is MapLight Therapeutics Inc (MPLT)'s business?

MapLight Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on improving the lives of patients suffering from debilitating central nervous system disorders (CNS). Its lead product candidate, ML-007C-MA, is a fixed-dose combination of an M1/M4 muscarinic agonist, ML-007, co-formulated with a peripherally acting anticholinergic (PAC), which it is initially developing for the treatment of schizophrenia and Alzheimer’s disease psychosis (ADP). ML-007C-MA is designed to activate both M1 and M4 muscarinic receptors in the CNS to drive efficacy, while synchronizing the pharmacokinetics of the agonist and antagonist components to mitigate peripheral cholinergic side effects. Its second product candidate, ML-004, is a 5-HT1B/1D agonist that the Company is developing for the treatment of social communication deficit and/or irritability in autism spectrum disorder. It is also advancing two preclinical programs, ML-021 and ML-009.

What is the price predicton of MPLT Stock?

Wall Street analysts forecast MPLT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MPLT is31.00 USD with a low forecast of 28.00 USD and a high forecast of 34.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is MapLight Therapeutics Inc (MPLT)'s revenue for the last quarter?

MapLight Therapeutics Inc revenue for the last quarter amounts to -19.98M USD, decreased

What is MapLight Therapeutics Inc (MPLT)'s earnings per share (EPS) for the last quarter?

MapLight Therapeutics Inc. EPS for the last quarter amounts to -17820000.00 USD, decreased

How many employees does MapLight Therapeutics Inc (MPLT). have?

MapLight Therapeutics Inc (MPLT) has 0 emplpoyees as of March 17 2026.

What is MapLight Therapeutics Inc (MPLT) market cap?

Today MPLT has the market capitalization of 857.10M USD.