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MPLT Overview

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ET
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0.000
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ET
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Intellectia

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High
29.720
Open
28.460
VWAP
28.75
Vol
176.88K
Mkt Cap
1.30B
Low
27.790
Amount
5.08M
EV/EBITDA(TTM)
--
Total Shares
45.35M
EV
992.67M
EV/OCF(TTM)
--
P/S(TTM)
--
MapLight Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on improving the lives of patients suffering from debilitating central nervous system disorders (CNS). Its lead product candidate, ML-007C-MA, is a fixed-dose combination of an M1/M4 muscarinic agonist, ML-007, co-formulated with a peripherally acting anticholinergic (PAC), which it is initially developing for the treatment of schizophrenia and Alzheimer’s disease psychosis (ADP). ML-007C-MA is designed to activate both M1 and M4 muscarinic receptors in the CNS to drive efficacy, while synchronizing the pharmacokinetics of the agonist and antagonist components to mitigate peripheral cholinergic side effects. Its second product candidate, ML-004, is a 5-HT1B/1D agonist that the Company is developing for the treatment of social communication deficit and/or irritability in autism spectrum disorder. It is also advancing two preclinical programs, ML-021 and ML-009.
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Events Timeline

(ET)
2026-05-14
16:30:00
MapLight Enters Key Inflection Point, Advancing Clinical Trials
select
2026-05-01 (ET)
2026-05-01
07:20:00
MapLight Completes Enrollment in Phase 2 ZEPHYR Trial for ML-007C-MA
select
2026-01-09 (ET)
2026-01-09
07:10:00
MapLight Therapeutics Updates Timing for ZEPHYR and IRIS Clinical Study Results
select

News

Fool
5.0
05-15Fool
MapLight CFO's Stock Sale Raises Investor Concerns
  • Stock Sale Overview: Setia Vishwas, CFO of MapLight Therapeutics, sold 36,371 shares of common stock through multiple open-market transactions from May 4 to May 6, 2026, totaling approximately $1.02 million, indicating liquidity in his holdings.
  • Ownership Change Analysis: This transaction reduced Vishwas's direct common stock holdings by 9.3%, leaving him with 356,256 shares, and while the sale was significant, it does not reflect a shift in his long-term confidence in the company.
  • Trading Plan Context: The stock sale was executed under a Rule 10b5-1 trading plan adopted by Vishwas on December 29, 2025, suggesting that the sale was based on predetermined criteria rather than a direct indication of the company's future performance.
  • Market Performance and Outlook: As of May 6, 2026, MapLight's stock has gained 70.8% over the past year, and despite the company being unprofitable, the expansion of its clinical pipeline and upcoming data releases may attract investor interest.
seekingalpha
9.5
05-15seekingalpha
MapLight Therapeutics Reports Q1 Losses and Cash Position
  • Financial Performance: MapLight Therapeutics reported a GAAP EPS of -$1.34 for Q1 2026, indicating significant challenges in profitability and reflecting ongoing financial pressures on the company.
  • Net Loss Overview: The net loss for the first quarter reached $60.7 million, a substantial increase from $22.3 million in Q1 2025, highlighting the urgent need for improvements in cost control and revenue growth.
  • Cash Position: At the end of the quarter, the company had $395.2 million in cash, cash equivalents, and investments, which is expected to fund operations through 2027, indicating relative liquidity in the short term.
  • Future Outlook: Despite the current financial difficulties, the ample cash reserves provide the company with opportunities to continue research and operations, and if it can effectively manage costs and drive revenue growth, it may achieve profitability in the future.
Fool
5.0
05-04Fool
MapLight Therapeutics Executive Sells Shares
  • Executive Stock Sale: Jonathan Gillis, Chief Administrative Officer of MapLight Therapeutics, disclosed the direct sale of 69,835 shares of common stock on April 27 and 28, 2026, totaling approximately $2.09 million, indicating a strategic liquidity management approach.
  • Transaction Plan Context: This sale was executed under a Rule 10b5-1 trading plan established on December 26, 2025, suggesting that it was a pre-scheduled routine transaction rather than an impulsive sell-off, thereby mitigating insider trading concerns.
  • Shareholding Changes: Post-transaction, Gillis retains 181,219 shares of common stock, valued at around $5.49 million, reflecting his continued confidence in the company's future prospects.
  • Market Reaction and Analysis: Although Gillis's sale contributed to an 8.63% drop in stock price, analysts remain optimistic about MapLight's potential, citing its innovative focus on central nervous system therapeutics as a significant market opportunity.
NASDAQ.COM
9.0
05-01NASDAQ.COM
MapLight Completes Enrollment in Schizophrenia Trial
  • Trial Enrollment Completed: MapLight Therapeutics has completed enrollment of 307 schizophrenia patients in its Phase 2 ZEPHYR trial, marking a significant milestone as the company advances mid-stage programs, with topline results expected by mid-August 2026, potentially impacting future growth positively.
  • IRIS Trial Progress: Concurrently, the IRIS trial has also enrolled 161 participants with autism spectrum disorder, including over 100 adolescents, with the primary endpoint assessing changes in social communication skills over 12 weeks, demonstrating the company's ongoing commitment to CNS disorders.
  • Strong Market Demand: CEO Chris Kroeger highlighted that robust enrollment reflects the significant unmet needs in central nervous system disorders, indicating the strategic importance of the company's research and development efforts in this area.
  • Stock Performance: MPLT's stock has traded between $12.24 and $33.28 over the past year, closing at $31.87 on Thursday with a 5.22% increase, suggesting positive market expectations regarding the company's future potential.
Yahoo Finance
9.5
04-26Yahoo Finance
Analysis of MapLight Therapeutics' Cash Burn
  • Cash Reserve Status: As of December 2025, MapLight Therapeutics holds $305 million in cash and is debt-free, providing a cash runway of approximately 2.2 years, despite an annual cash burn of $139 million, indicating the company's ability to manage funds in its early stage.
  • Cash Burn Increase: Over the past year, MapLight's cash burn has surged by 74%, which may suggest accelerated business development; however, this also means a faster depletion of cash reserves, potentially impacting future fundraising capabilities.
  • Market Capitalization and Fundraising Ability: With a market capitalization of $1.3 billion, MapLight's cash burn accounted for 11% of its market value last year, indicating a strong capacity to raise funds through share issuance in the coming year, albeit at the cost of shareholder dilution.
  • Risk Assessment: While MapLight's cash reserve situation is reassuring, the increasing cash burn rate raises concerns about the company's future growth, prompting investors to monitor potential risk signals to make informed investment decisions.
Fool
5.0
04-22Fool
MapLight Therapeutics Executive Sells Shares Amid Routine Liquidity Management
  • Executive Stock Sale: Anatol Kreitzer, the Chief Discovery Officer of MapLight Therapeutics, sold 3,316 shares of common stock for approximately $88,000, reflecting a routine liquidity management strategy rather than a shift in conviction.
  • Minimal Ownership Change: The sale constituted just 1% of Kreitzer's direct holdings, leaving him with 256,612 shares valued at about $6.9 million post-transaction, indicating sustained confidence in the company's prospects.
  • Financial Overview: MapLight ended 2025 with $453.1 million in cash, sufficient to fund operations through 2027, despite R&D spending projected to rise to $138.3 million and quarterly net losses widening to $79.5 million.
  • Clinical Trial Outlook: The company expects to complete Phase 2 enrollment for its lead schizophrenia program this month, with topline data due in Q3, and the clustering of multiple trial results could serve as significant valuation catalysts.
Wall Street analysts forecast MPLT stock price to rise
4 Analyst Rating
Wall Street analysts forecast MPLT stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
28.00
Averages
31.00
High
34.00
Current: 0.000
sliders
Low
28.00
Averages
31.00
High
34.00
LifeSci Capital
Outperform
initiated
$45
AI Analysis
2026-05-14
New
Reason
LifeSci Capital
Price Target
$45
AI Analysis
2026-05-14
New
initiated
Outperform
Reason
LifeSci Capital initiated coverage of MapLight Therapeutics with an Outperform rating and $45 price target.
H.C. Wainwright
Raghuram Selvaraju
initiated
$45
2026-05-04
Reason
H.C. Wainwright
Raghuram Selvaraju
Price Target
$45
2026-05-04
initiated
Reason
H.C. Wainwright analyst Raghuram Selvaraju initiated coverage of MapLight Therapeutics with a Buy rating and $45 price target. MapLight is a clinical-stage biopharmaceutical company focused on improving the lives of patients suffering from debilitating central nervous system disorders, the analyst tells investors in a research note. The firm believes MapLight's lead candidate could generate peak sales approaching $4B annually if approved in both schizophrenia and Alzheimer's disease psychosis.
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Valuation Metrics

The current forward P/E ratio for MapLight Therapeutics Inc (MPLT.O) is 0.00, compared to its 5-year average forward P/E of -4.45. For a more detailed relative valuation and DCF analysis to assess MapLight Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.45
Current PE
0.00
Overvalued PE
-3.79
Undervalued PE
-5.11

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.14
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-4.52
Undervalued EV/EBITDA
-5.76

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

Whales Holding MPLT

N
Novo Holdings A/S
Holding
MPLT
-9.26%
3M Return

Trading Trends

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Frequently Asked Questions

What is MapLight Therapeutics Inc (MPLT) stock price today?

The current price of MPLT is 28.73 USD — it has decreased -1.91

What is MapLight Therapeutics Inc (MPLT)'s business?

MapLight Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on improving the lives of patients suffering from debilitating central nervous system disorders (CNS). Its lead product candidate, ML-007C-MA, is a fixed-dose combination of an M1/M4 muscarinic agonist, ML-007, co-formulated with a peripherally acting anticholinergic (PAC), which it is initially developing for the treatment of schizophrenia and Alzheimer’s disease psychosis (ADP). ML-007C-MA is designed to activate both M1 and M4 muscarinic receptors in the CNS to drive efficacy, while synchronizing the pharmacokinetics of the agonist and antagonist components to mitigate peripheral cholinergic side effects. Its second product candidate, ML-004, is a 5-HT1B/1D agonist that the Company is developing for the treatment of social communication deficit and/or irritability in autism spectrum disorder. It is also advancing two preclinical programs, ML-021 and ML-009.

What is the price predicton of MPLT Stock?

Wall Street analysts forecast MPLT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MPLT is31.00 USD with a low forecast of 28.00 USD and a high forecast of 34.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is MapLight Therapeutics Inc (MPLT)'s revenue for the last quarter?

MapLight Therapeutics Inc revenue for the last quarter amounts to -64.50M USD, decreased

What is MapLight Therapeutics Inc (MPLT)'s earnings per share (EPS) for the last quarter?

MapLight Therapeutics Inc. EPS for the last quarter amounts to -51202000.00 USD, decreased

How many employees does MapLight Therapeutics Inc (MPLT). have?

MapLight Therapeutics Inc (MPLT) has 133 emplpoyees as of May 18 2026.

What is MapLight Therapeutics Inc (MPLT) market cap?

Today MPLT has the market capitalization of 1.30B USD.