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MPLT Overview

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Intellectia

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High
30.370
Open
28.090
VWAP
29.04
Vol
530.96K
Mkt Cap
1.26B
Low
27.000
Amount
15.42M
EV/EBITDA(TTM)
--
Total Shares
42.44M
EV
957.80M
EV/OCF(TTM)
--
P/S(TTM)
--
MapLight Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on improving the lives of patients suffering from debilitating central nervous system disorders (CNS). Its lead product candidate, ML-007C-MA, is a fixed-dose combination of an M1/M4 muscarinic agonist, ML-007, co-formulated with a peripherally acting anticholinergic (PAC), which it is initially developing for the treatment of schizophrenia and Alzheimer’s disease psychosis (ADP). ML-007C-MA is designed to activate both M1 and M4 muscarinic receptors in the CNS to drive efficacy, while synchronizing the pharmacokinetics of the agonist and antagonist components to mitigate peripheral cholinergic side effects. Its second product candidate, ML-004, is a 5-HT1B/1D agonist that the Company is developing for the treatment of social communication deficit and/or irritability in autism spectrum disorder. It is also advancing two preclinical programs, ML-021 and ML-009.
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Events Timeline

(ET)
2026-01-09
07:10:00
MapLight Therapeutics Updates Timing for ZEPHYR and IRIS Clinical Study Results
select
2026-01-05 (ET)
2026-01-05
07:10:00
MapLight Receives FDA Fast Track Designation for ML-007C-MA
select
2025-12-16 (ET)
2025-12-16
07:10:00
SandboxAQ and MapLight Enter Strategic Collaboration with Potential Payments Up to $200M
select

News

Yahoo Finance
9.5
04-26Yahoo Finance
PinnedAnalysis of MapLight Therapeutics' Cash Burn
  • Cash Reserve Status: As of December 2025, MapLight Therapeutics holds $305 million in cash and is debt-free, providing a cash runway of approximately 2.2 years, despite an annual cash burn of $139 million, indicating the company's ability to manage funds in its early stage.
  • Cash Burn Increase: Over the past year, MapLight's cash burn has surged by 74%, which may suggest accelerated business development; however, this also means a faster depletion of cash reserves, potentially impacting future fundraising capabilities.
  • Market Capitalization and Fundraising Ability: With a market capitalization of $1.3 billion, MapLight's cash burn accounted for 11% of its market value last year, indicating a strong capacity to raise funds through share issuance in the coming year, albeit at the cost of shareholder dilution.
  • Risk Assessment: While MapLight's cash reserve situation is reassuring, the increasing cash burn rate raises concerns about the company's future growth, prompting investors to monitor potential risk signals to make informed investment decisions.
Fool
5.0
04-22Fool
MapLight Therapeutics Executive Sells Shares Amid Routine Liquidity Management
  • Executive Stock Sale: Anatol Kreitzer, the Chief Discovery Officer of MapLight Therapeutics, sold 3,316 shares of common stock for approximately $88,000, reflecting a routine liquidity management strategy rather than a shift in conviction.
  • Minimal Ownership Change: The sale constituted just 1% of Kreitzer's direct holdings, leaving him with 256,612 shares valued at about $6.9 million post-transaction, indicating sustained confidence in the company's prospects.
  • Financial Overview: MapLight ended 2025 with $453.1 million in cash, sufficient to fund operations through 2027, despite R&D spending projected to rise to $138.3 million and quarterly net losses widening to $79.5 million.
  • Clinical Trial Outlook: The company expects to complete Phase 2 enrollment for its lead schizophrenia program this month, with topline data due in Q3, and the clustering of multiple trial results could serve as significant valuation catalysts.
NASDAQ.COM
8.5
04-09NASDAQ.COM
Biotech Stocks Reach New 52-Week Highs
  • Relay Therapeutics Progress: Relay Therapeutics' drug candidate Zovegalisib showed promising results in clinical trials, with a 7.64% stock price increase to $14.64 on Wednesday, indicating the company's potential in treating HR+/HER2- breast cancer, with initial data expected in the first half of 2026.
  • MapLight Therapeutics High: MapLight Therapeutics' stock reached $25.79 during trading yesterday, up from its IPO price of $17.00, reflecting market optimism for its drug ML-007C-MA targeting schizophrenia and Alzheimer's disease, with trial results anticipated in Q3 2026.
  • Oruka Therapeutics Development: Oruka Therapeutics' ORKA-001 and ORKA-002 are in clinical trials for psoriasis, with the stock hitting $64.61, showcasing market confidence in its drugs, and significant data expected in Q2 2026.
  • Spyre Therapeutics Clinical Trials: Spyre Therapeutics' stock reached $54.33 yesterday, reflecting market interest in its investigational therapies, particularly the SKYLINE trial for active ulcerative colitis, with preliminary data expected in Q3 2026.
NASDAQ.COM
9.5
03-26NASDAQ.COM
MapLight Reports 2025 Financial Results and Clinical Milestones
  • Increased Financial Losses: MapLight Therapeutics reported a net loss of $79.5 million for Q4 2025, significantly up from $21.2 million in the same period last year, with a total annual net loss of $161.2 million compared to $77.6 million in 2024, indicating ongoing pressure from R&D investments.
  • Clinical Trial Progress: The company is advancing its ML-007C-MA drug in the ZEPHYR trial for schizophrenia, with enrollment expected to complete in April 2026 and topline results planned for Q3 2026, marking a critical milestone for future development.
  • Multiple Drug Developments: MapLight is also progressing with ML-004 for autism spectrum disorder in the IRIS trial, which has completed enrollment, with topline data expected in Q3 2026, while candidate nomination for ML-055 is anticipated in 2026, showcasing the company's active pipeline across multiple R&D fronts.
  • Strong Cash Position: As of 2025, MapLight holds $453.1 million in cash and investments, which is expected to fund operations through 2027, providing a financial cushion despite the losses and ensuring continued support for its R&D efforts.
seekingalpha
9.5
03-26seekingalpha
MapLight Therapeutics Reports Q4 Financial Results
  • Earnings Report: MapLight Therapeutics reported a GAAP EPS of -$2.47 for Q4, indicating challenges in profitability that may affect investor confidence moving forward.
  • Cash Reserves: As of December 31, 2025, the company had $453.1 million in cash, cash equivalents, and investments, suggesting a reasonable liquidity cushion for ongoing operations.
  • Funding Outlook: Based on current operational plans and assumptions, the company expects its existing cash and investments to be sufficient to fund operations through 2027, reflecting management's confidence in future financial stability.
  • Historical Financial Data: The historical earnings data for MapLight Therapeutics provides context on the company's past performance, aiding investors in assessing its long-term growth potential and associated risks.
moomoo
9.5
03-26moomoo
Maplight Therapeutics Inc. Reports Q4 Net Loss of $79.5 Million, Q4 EPS at -$2.47
  • Financial Performance: Maplight reported a net loss of $79.5 million for Q4.
  • Earnings Per Share: The company's earnings per share (EPS) for the quarter was -$2.47.
Wall Street analysts forecast MPLT stock price to rise
4 Analyst Rating
Wall Street analysts forecast MPLT stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
28.00
Averages
31.00
High
34.00
Current: 0.000
sliders
Low
28.00
Averages
31.00
High
34.00
Needham
Buy
initiated
$37
AI Analysis
2026-04-08
Reason
Needham
Price Target
$37
AI Analysis
2026-04-08
initiated
Buy
Reason
Needham initiated coverage of MapLight Therapeutics with a Buy rating and $37 price target. The firm believes the muscarinic class is likely to be "disruptive," with application across multiple indications including schizophrenia and Alzheimer's disease psychosis. MapLight 's ML-007C-MA should be "differentiated" from Cobenfy in schizophrenia on tolerability and convenience, supporting $1.5B in sales by 2035, the analyst tells investors in a research note.
TD Cowen
Buy
initiated
2026-04-07
Reason
TD Cowen
Price Target
2026-04-07
initiated
Buy
Reason
TD Cowen initiated coverage of MapLight Therapeutics with a Buy rating and no price target. The company is advancing candidates for the treatment of central nervous system and neuropsychic conditions, the analyst tells investors in a research note. The firm says MapLight's lead asset ML-007C-MA looks to improve upon Cobenfy's profile in the treatment of schizophrenia with a Phase II readout set for Q3. TD views the shares as undervalued for the company's schizophrenia opportunity alone.
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Valuation Metrics

The current forward P/E ratio for MapLight Therapeutics Inc (MPLT.O) is 0.00, compared to its 5-year average forward P/E of -4.45. For a more detailed relative valuation and DCF analysis to assess MapLight Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.45
Current PE
0.00
Overvalued PE
-3.79
Undervalued PE
-5.11

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.14
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-4.52
Undervalued EV/EBITDA
-5.76

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

Whales Holding MPLT

N
Novo Holdings A/S
Holding
MPLT
-35.12%
3M Return

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Frequently Asked Questions

What is MapLight Therapeutics Inc (MPLT) stock price today?

The current price of MPLT is 29.76 USD — it has increased 2.23

What is MapLight Therapeutics Inc (MPLT)'s business?

MapLight Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on improving the lives of patients suffering from debilitating central nervous system disorders (CNS). Its lead product candidate, ML-007C-MA, is a fixed-dose combination of an M1/M4 muscarinic agonist, ML-007, co-formulated with a peripherally acting anticholinergic (PAC), which it is initially developing for the treatment of schizophrenia and Alzheimer’s disease psychosis (ADP). ML-007C-MA is designed to activate both M1 and M4 muscarinic receptors in the CNS to drive efficacy, while synchronizing the pharmacokinetics of the agonist and antagonist components to mitigate peripheral cholinergic side effects. Its second product candidate, ML-004, is a 5-HT1B/1D agonist that the Company is developing for the treatment of social communication deficit and/or irritability in autism spectrum disorder. It is also advancing two preclinical programs, ML-021 and ML-009.

What is the price predicton of MPLT Stock?

Wall Street analysts forecast MPLT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MPLT is31.00 USD with a low forecast of 28.00 USD and a high forecast of 34.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is MapLight Therapeutics Inc (MPLT)'s revenue for the last quarter?

MapLight Therapeutics Inc revenue for the last quarter amounts to -83.38M USD, decreased

What is MapLight Therapeutics Inc (MPLT)'s earnings per share (EPS) for the last quarter?

MapLight Therapeutics Inc. EPS for the last quarter amounts to -17820000.00 USD, decreased

How many employees does MapLight Therapeutics Inc (MPLT). have?

MapLight Therapeutics Inc (MPLT) has 133 emplpoyees as of April 28 2026.

What is MapLight Therapeutics Inc (MPLT) market cap?

Today MPLT has the market capitalization of 1.26B USD.