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MPLT Overview

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ET
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0.000
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ET
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Intellectia

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High
22.939
Open
21.220
VWAP
22.26
Vol
226.54K
Mkt Cap
898.38M
Low
21.220
Amount
5.04M
EV/EBITDA(TTM)
--
Total Shares
42.44M
EV
593.27M
EV/OCF(TTM)
--
P/S(TTM)
--
MapLight Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on improving the lives of patients suffering from debilitating central nervous system disorders (CNS). Its lead product candidate, ML-007C-MA, is a fixed-dose combination of an M1/M4 muscarinic agonist, ML-007, co-formulated with a peripherally acting anticholinergic (PAC), which it is initially developing for the treatment of schizophrenia and Alzheimer’s disease psychosis (ADP). ML-007C-MA is designed to activate both M1 and M4 muscarinic receptors in the CNS to drive efficacy, while synchronizing the pharmacokinetics of the agonist and antagonist components to mitigate peripheral cholinergic side effects. Its second product candidate, ML-004, is a 5-HT1B/1D agonist that the Company is developing for the treatment of social communication deficit and/or irritability in autism spectrum disorder. It is also advancing two preclinical programs, ML-021 and ML-009.
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Events Timeline

(ET)
2026-01-09
07:10:00
MapLight Therapeutics Updates Timing for ZEPHYR and IRIS Clinical Study Results
select
2026-01-05 (ET)
2026-01-05
07:10:00
MapLight Receives FDA Fast Track Designation for ML-007C-MA
select
2025-12-16 (ET)
2025-12-16
07:10:00
SandboxAQ and MapLight Enter Strategic Collaboration with Potential Payments Up to $200M
select

News

NASDAQ.COM
9.5
03-26NASDAQ.COM
MapLight Reports 2025 Financial Results and Clinical Milestones
  • Increased Financial Losses: MapLight Therapeutics reported a net loss of $79.5 million for Q4 2025, significantly up from $21.2 million in the same period last year, with a total annual net loss of $161.2 million compared to $77.6 million in 2024, indicating ongoing pressure from R&D investments.
  • Clinical Trial Progress: The company is advancing its ML-007C-MA drug in the ZEPHYR trial for schizophrenia, with enrollment expected to complete in April 2026 and topline results planned for Q3 2026, marking a critical milestone for future development.
  • Multiple Drug Developments: MapLight is also progressing with ML-004 for autism spectrum disorder in the IRIS trial, which has completed enrollment, with topline data expected in Q3 2026, while candidate nomination for ML-055 is anticipated in 2026, showcasing the company's active pipeline across multiple R&D fronts.
  • Strong Cash Position: As of 2025, MapLight holds $453.1 million in cash and investments, which is expected to fund operations through 2027, providing a financial cushion despite the losses and ensuring continued support for its R&D efforts.
seekingalpha
9.5
03-26seekingalpha
MapLight Therapeutics Reports Q4 Financial Results
  • Earnings Report: MapLight Therapeutics reported a GAAP EPS of -$2.47 for Q4, indicating challenges in profitability that may affect investor confidence moving forward.
  • Cash Reserves: As of December 31, 2025, the company had $453.1 million in cash, cash equivalents, and investments, suggesting a reasonable liquidity cushion for ongoing operations.
  • Funding Outlook: Based on current operational plans and assumptions, the company expects its existing cash and investments to be sufficient to fund operations through 2027, reflecting management's confidence in future financial stability.
  • Historical Financial Data: The historical earnings data for MapLight Therapeutics provides context on the company's past performance, aiding investors in assessing its long-term growth potential and associated risks.
moomoo
9.5
03-26moomoo
Maplight Therapeutics Inc. Reports Q4 Net Loss of $79.5 Million, Q4 EPS at -$2.47
  • Financial Performance: Maplight reported a net loss of $79.5 million for Q4.
  • Earnings Per Share: The company's earnings per share (EPS) for the quarter was -$2.47.
NASDAQ.COM
5.0
02-23NASDAQ.COM
Maplight and CVRx Executives Increase Stock Holdings
  • Maplight Purchase: George Pavlov of Maplight Therapeutics made a $441,168 purchase of 25,000 shares of MPLT at $17.65 each on Friday, marking his first buy in the past twelve months, indicating confidence in the company's future prospects.
  • Market Performance: On Monday, Maplight Therapeutics' stock traded down approximately 1.4%, and while Pavlov's purchase may not have immediately boosted the stock price, his long-term investment intentions could influence market sentiment.
  • CVRx Purchase: Mudit K. Jain also bought $297,592 worth of CVRx, acquiring 46,800 shares at $6.36 each on Friday, which is his third purchase in the past twelve months, reflecting his ongoing optimism about CVRx.
  • Stock Fluctuation: CVRx's stock rose about 12.1% on Monday, reaching a high of $7.22, with Jain's investment up approximately 13.5% at the peak, showcasing a positive market reaction to CVRx.
renaissancecapital
8.5
01-09renaissancecapital
Aktis Oncology Launches $200 Million IPO with $100 Million Investment from Eli Lilly
  • IPO Market Recovery: Aktis Oncology launched a $200 million IPO on Monday, indicating a resurgence in the biotech IPO market after a period of uneven performance, and is set to be the first significant IPO of 2026.
  • Increased Financing Size: Just two days after the IPO launch, Aktis upsized the deal by 50%, which not only reflects growing investor confidence in its prospects but also indicates a rising interest in the biotech sector.
  • Strategic Partnership Support: Aktis disclosed a $100 million investment from partner Eli Lilly, which will provide robust support for the company's R&D and market expansion, further strengthening its position in the competitive biotech landscape.
  • Optimistic Market Outlook: As the first major biotech IPO of 2026, Aktis's success could attract more investor attention to the biotech sector, potentially driving recovery and growth across the industry.
Globenewswire
9.0
01-09Globenewswire
MapLight Accelerates Phase 2 Trial Timelines for Schizophrenia and Autism Studies
  • Clinical Trial Progress: MapLight Therapeutics' ZEPHYR trial is accelerating enrollment, with topline results for 300 schizophrenia patients now expected in Q3 2026, showcasing the company's efficient execution under high-quality standards.
  • IRIS Trial Update: The IRIS trial has completed enrollment, with topline results for approximately 160 autism patients also anticipated in Q3 2026, further enhancing the company's research capabilities in central nervous system disorders.
  • Strategic Commitment: CEO Chris Kroeger emphasized that the rapid enrollment pace not only narrows timing guidance but also demonstrates the company's commitment to advancing its programs, potentially boosting investor confidence and attracting more funding support.
  • Market Potential: With a focus on developing drugs for mental health disorders, MapLight is positioned to fill the market gap for specific therapies as clinical trials progress, driving future business growth.
Wall Street analysts forecast MPLT stock price to rise
4 Analyst Rating
Wall Street analysts forecast MPLT stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
28.00
Averages
31.00
High
34.00
Current: 0.000
sliders
Low
28.00
Averages
31.00
High
34.00
TD Cowen
Buy
initiated
AI Analysis
2026-04-07
New
Reason
TD Cowen
Price Target
AI Analysis
2026-04-07
New
initiated
Buy
Reason
TD Cowen initiated coverage of MapLight Therapeutics with a Buy rating and no price target. The company is advancing candidates for the treatment of central nervous system and neuropsychic conditions, the analyst tells investors in a research note. The firm says MapLight's lead asset ML-007C-MA looks to improve upon Cobenfy's profile in the treatment of schizophrenia with a Phase II readout set for Q3. TD views the shares as undervalued for the company's schizophrenia opportunity alone.
Canaccord
NULL -> Buy
initiated
$35
2026-03-19
Reason
Canaccord
Price Target
$35
2026-03-19
initiated
NULL -> Buy
Reason
Canaccord initiated coverage of MapLight Therapeutics with a Buy rating and $35 price target.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MPLT
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Valuation Metrics

The current forward P/E ratio for MapLight Therapeutics Inc (MPLT.O) is 0.00, compared to its 5-year average forward P/E of -4.45. For a more detailed relative valuation and DCF analysis to assess MapLight Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.45
Current PE
0.00
Overvalued PE
-3.79
Undervalued PE
-5.11

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.14
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-4.52
Undervalued EV/EBITDA
-5.76

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
Quarterly

Whales Holding MPLT

N
Novo Holdings A/S
Holding
MPLT
-34.62%
3M Return

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Frequently Asked Questions

What is MapLight Therapeutics Inc (MPLT) stock price today?

The current price of MPLT is 22.61 USD — it has increased 6.8

What is MapLight Therapeutics Inc (MPLT)'s business?

MapLight Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on improving the lives of patients suffering from debilitating central nervous system disorders (CNS). Its lead product candidate, ML-007C-MA, is a fixed-dose combination of an M1/M4 muscarinic agonist, ML-007, co-formulated with a peripherally acting anticholinergic (PAC), which it is initially developing for the treatment of schizophrenia and Alzheimer’s disease psychosis (ADP). ML-007C-MA is designed to activate both M1 and M4 muscarinic receptors in the CNS to drive efficacy, while synchronizing the pharmacokinetics of the agonist and antagonist components to mitigate peripheral cholinergic side effects. Its second product candidate, ML-004, is a 5-HT1B/1D agonist that the Company is developing for the treatment of social communication deficit and/or irritability in autism spectrum disorder. It is also advancing two preclinical programs, ML-021 and ML-009.

What is the price predicton of MPLT Stock?

Wall Street analysts forecast MPLT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MPLT is31.00 USD with a low forecast of 28.00 USD and a high forecast of 34.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is MapLight Therapeutics Inc (MPLT)'s revenue for the last quarter?

MapLight Therapeutics Inc revenue for the last quarter amounts to -83.38M USD, decreased

What is MapLight Therapeutics Inc (MPLT)'s earnings per share (EPS) for the last quarter?

MapLight Therapeutics Inc. EPS for the last quarter amounts to -17820000.00 USD, decreased

How many employees does MapLight Therapeutics Inc (MPLT). have?

MapLight Therapeutics Inc (MPLT) has 0 emplpoyees as of April 08 2026.

What is MapLight Therapeutics Inc (MPLT) market cap?

Today MPLT has the market capitalization of 898.38M USD.