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MAZE Should I Buy

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Intellectia

Should You Buy Maze Therapeutics Inc (MAZE) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
51.050
1 Day change
13.30%
52 Week Range
51.360
Analysis Updated At
2026/03/06
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Maze Therapeutics Inc (MAZE) is not a strong buy at the moment for a beginner investor with a long-term strategy. The technical indicators are neutral, options data suggests a lack of strong bullish sentiment, and the company's financial performance shows significant challenges with no revenue and negative income. While analysts have raised price targets and maintain a Buy rating, the lack of recent news or significant positive catalysts makes this stock a hold for now.

Technical Analysis

The MACD histogram is negative and expanding (-0.248), indicating bearish momentum. RSI is neutral at 47.308, and moving averages are converging, showing no clear trend. The stock is trading near its pivot level (45.34), with resistance at 47.055 and support at 43.624.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Options data shows a low put-call ratio, indicating some bullish sentiment, but the low volume and high implied volatility (214.98 with IV rank at 99.15) suggest uncertainty and risk.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
2
Buy
16

Positive Catalysts

  • The upcoming MZE-829 data and HORIZON data in APOL1-mediated kidney disease are potential catalysts.

Neutral/Negative Catalysts

  • The company's financials are weak, with no revenue and significant losses. Technical indicators do not show a strong bullish trend. There is no recent news or significant trading activity from insiders, hedge funds, or Congress.

Financial Performance

In 2025/Q3, the company reported zero revenue (-100% YoY), a net income of -$30.087M (up 1139.68% YoY), and EPS of -0.66 (up 1000% YoY). Gross margin dropped to 0 (-100% YoY). The financials indicate significant challenges in profitability and growth.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts maintain a Buy rating and have raised price targets multiple times, with the latest target at $58. They are optimistic about the upcoming data releases and see favorable risk/reward dynamics despite recent stock outperformance.

Wall Street analysts forecast MAZE stock price to rise
8 Analyst Rating
Wall Street analysts forecast MAZE stock price to rise
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 45.060
sliders
Low
46
Averages
52
High
60
Current: 45.060
sliders
Low
46
Averages
52
High
60
Mizuho
Outperform
initiated
$97
AI Analysis
2026-03-10
New
Reason
Mizuho
Price Target
$97
AI Analysis
2026-03-10
New
initiated
Outperform
Reason
Mizuho initiated coverage of Maze Therapeutics with an Outperform rating and $97 price target. The firm says Maze's first two drug candidate programs, MZE829 and MZE782, have high revenue "potency." It models $8B of peak revenue for thee two programs combined. This "could potentially allow for disproportionate value creation" over the next 5-10 years, the analyst tells investors in a research note.
Guggenheim
Buy
maintain
$46 -> $58
2026-03-04
Reason
Guggenheim
Price Target
$46 -> $58
2026-03-04
maintain
Buy
Reason
Guggenheim raised the firm's price target on Maze Therapeutics to $58 from $46 and keeps a Buy rating on the shares after the firm discussed the upcoming MZE-829 data in APOL1 primary or diabetic AMKD with six nephrologists.
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