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MAZE Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
OverviewStock Price PredictionTechnicalValuationFinancialsEarningsShould I BuyNews & Events
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Intellectia

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High
51.360
Open
46.290
VWAP
49.17
Vol
1.29M
Mkt Cap
2.46B
Low
45.100
Amount
63.41M
EV/EBITDA(TTM)
--
Total Shares
48.12M
EV
--
EV/OCF(TTM)
--
P/S(TTM)
--
Maze Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in harnessing the power of human genetics and variant functionalization with its Maze Compass platform to develop small-molecule precision medicines for the treatment of renal, cardiovascular and related metabolic diseases, including obesity. The Compass platform has been purpose-built to inform all phases of drug discovery and development process through clinical trial design, advancing two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach to chronic kidney disease (CKD). Its lead program, MZE829, is an oral, small-molecule inhibitor of apolipoprotein L1, or APOL1, for the treatment of patients with APOL1 kidney disease, or AKD. Its second lead program, MZE782, is an oral, small-molecule inhibitor of the solute transporter SLC6A19, a novel CKD target.
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Events Timeline

(ET)
2025-11-06
16:19:01
Maze Therapeutics announces Q3 earnings per share of 66 cents, falling short of consensus estimate of 69 cents.
select

News

Benzinga
6.5
03-10Benzinga
Wall Street Analysts Adjust Ratings on Key Stocks
  • Analyst Rating Changes: Top Wall Street analysts have adjusted their ratings on several stocks, including upgrades, downgrades, and initiations, reflecting varying market perspectives on these companies.
  • Market Dynamics: While specific stock names are not mentioned, changes in analyst ratings typically influence investor decisions and can lead to price volatility in the affected stocks.
  • Investor Focus: Investors considering purchasing MSTR stock should pay attention to the latest insights from analysts to make more informed investment choices.
  • Information Source: A complete view of all analyst rating changes can be found on Benzinga's analyst ratings page, providing a comprehensive market perspective.
Newsfilter
2.0
03-03Newsfilter
Chronic Kidney Disease Market Growth Drivers
  • Market Size Growth: According to analysis, the chronic kidney disease (CKD) market size was approximately $4.8 billion in 2024 and is expected to grow further by 2034, reflecting increased demand for new therapies and an expanding patient base.
  • Rising Patient Numbers: In 2024, there were about 82 million prevalent cases of CKD across the 7 major markets (7MM), with projections indicating continued growth from 2025 to 2034, primarily driven by an aging population and the rising prevalence of diabetes and hypertension.
  • Launch of New Therapies: The introduction of emerging therapies such as AstraZeneca's Zibotentan/Dapagliflozin and Boehringer Ingelheim's Vicadrostat + Empagliflozin is expected to significantly boost market growth and improve treatment outcomes for patients.
  • Advancements in Biomarkers: Progress in biomarkers like KIM-1 and NGAL enables more precise early detection of CKD, thereby enhancing the potential for timely interventions and improving overall patient prognosis.
Fool
8.5
02-18Fool
a16z Capital Management Acquires Navan Shares
  • New Investment Highlight: According to the SEC filing dated February 17, 2026, a16z Capital Management acquired approximately 27 million shares of Navan in Q4 2025, with an estimated transaction value of $464.5 million, indicating strong confidence in Navan's future growth potential.
  • Asset Allocation Shift: This acquisition positions Navan as 29.4% of a16z's reportable assets under management, reflecting its significant importance in the investment portfolio and potentially influencing future investment strategies.
  • Market Performance Analysis: As of December 31, 2025, Navan's share price was $9.97, with a current market price of $10.23 and a market capitalization of $2.54 billion, showcasing market recognition of its technology-driven enterprise spend management platform.
  • Business Model Transformation: Navan has evolved from a traditional travel booking tool to a comprehensive enterprise spend platform, integrating travel, payments, and expense management, thereby enhancing cost control and operational efficiency for businesses, attracting increased attention from corporate clients.
NASDAQ.COM
8.5
02-18NASDAQ.COM
a16z Capital Management Acquires Navan Shares
  • New Investment Scale: a16z Capital Management acquired 27,195,364 shares of Navan in Q4 2025, with an estimated transaction value of $464.50 million, significantly enhancing the diversity of its asset portfolio.
  • Asset Proportion Increase: Navan now accounts for 29.4% of a16z Capital Management's 13F reportable assets, making it the fund's second-largest holding, reflecting confidence in Navan's future growth potential.
  • Technology-Driven Business Model: Navan focuses on software solutions for enterprise travel and expense management, leveraging artificial intelligence to enhance operational efficiency and help companies achieve cost control, thereby strengthening its competitive position in the market.
  • Diversified Revenue Sources: Navan generates revenue from software subscriptions and payment transaction processing, providing a dual revenue model that ensures future financial stability while increasing its significance in enterprise spend management.
Fool
5.0
02-16Fool
Maze Therapeutics Executive Sells Stock Options
  • Executive Transaction Overview: Harold Bernstein, President of R&D at Maze Therapeutics, exercised 15,000 options on February 2, 2026, and sold the shares in an open-market transaction valued at approximately $690,300, fully divesting his direct ownership, which reflects executive confidence in the company's future.
  • Transaction Structure Analysis: This was a derivative transaction involving the exercise of 15,000 stock options followed by an immediate sale of the resulting shares, illustrating Bernstein's decision-making process that reduced his holdings from 90,000 shares to zero over the past year through a series of administrative transactions.
  • Investor Impact Assessment: Although Bernstein no longer holds direct shares, he retains nearly 300,000 stock options, and this transaction was part of a 10b5-1 trading plan, indicating that the sale does not reflect a negative outlook on the company, alleviating investor concerns.
  • Market Performance Review: Since its IPO on January 31, 2025, Maze Therapeutics has achieved a 158% annual increase in stock price within four months post-listing, and while a brief pullback may occur, Wall Street analysts widely consider the stock a strong buy as it continues to advance in clinical trials for multiple medicines.
NASDAQ.COM
5.0
02-16NASDAQ.COM
Maze Therapeutics Executive Sells Shares
  • Executive Stock Transaction: On February 2, 2026, Maze Therapeutics' Chief Medical Officer Harold Bernstein exercised 15,000 options and sold them immediately for approximately $690,300, indicating executive confidence in the company's future prospects.
  • Strong Market Performance: Celebrating its one-year anniversary, Maze Therapeutics has seen a 174% stock price increase over the past year, with a remarkable 158% rise in the first four months of 2025, reflecting strong demand for its products and positive investor sentiment.
  • Change in Shareholding Structure: Although Bernstein divested all his direct shares, he retains nearly 300,000 stock options, suggesting ongoing confidence in the company's future and that he has not fully exited his investment.
  • Analyst Perspectives: While Maze Therapeutics was not included in the current top investment stocks by The Motley Fool Stock Advisor, Wall Street analysts generally consider it a strong buy, indicating optimism regarding its progress in clinical trials.
Wall Street analysts forecast MAZE stock price to rise
8 Analyst Rating
Wall Street analysts forecast MAZE stock price to rise
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
46.00
Averages
52.00
High
60.00
Current: 0.000
sliders
Low
46.00
Averages
52.00
High
60.00
Mizuho
Outperform
initiated
$97
AI Analysis
2026-03-10
New
Reason
Mizuho
Price Target
$97
AI Analysis
2026-03-10
New
initiated
Outperform
Reason
Mizuho initiated coverage of Maze Therapeutics with an Outperform rating and $97 price target. The firm says Maze's first two drug candidate programs, MZE829 and MZE782, have high revenue "potency." It models $8B of peak revenue for thee two programs combined. This "could potentially allow for disproportionate value creation" over the next 5-10 years, the analyst tells investors in a research note.
Guggenheim
Buy
maintain
$46 -> $58
2026-03-04
Reason
Guggenheim
Price Target
$46 -> $58
2026-03-04
maintain
Buy
Reason
Guggenheim raised the firm's price target on Maze Therapeutics to $58 from $46 and keeps a Buy rating on the shares after the firm discussed the upcoming MZE-829 data in APOL1 primary or diabetic AMKD with six nephrologists.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MAZE
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Valuation Metrics

The current forward P/E ratio for Maze Therapeutics Inc (MAZE.O) is -12.79, compared to its 5-year average forward P/E of -5.86. For a more detailed relative valuation and DCF analysis to assess Maze Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.86
Current PE
-12.79
Overvalued PE
-1.98
Undervalued PE
-9.74

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.44
Current EV/EBITDA
-9.80
Overvalued EV/EBITDA
-2.04
Undervalued EV/EBITDA
-8.84

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
388.83
Current PS
1488.46
Overvalued PS
917.25
Undervalued PS
-139.58

Financials

AI Analysis
Annual
Quarterly

Whales Holding MAZE

F
Frazier Life Sciences Management, LP
Holding
MAZE
+9.72%
3M Return
B
Boothbay Fund Management, LLC
Holding
MAZE
+8.23%
3M Return
V
VR Management, LLC
Holding
MAZE
+6.00%
3M Return
T
TCG Crossover Management, LLC
Holding
MAZE
+1.37%
3M Return
L
Logos Global Management, L.P.
Holding
MAZE
-0.20%
3M Return
B
Bellevue Asset Management AG
Holding
MAZE
-2.17%
3M Return

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Frequently Asked Questions

What is Maze Therapeutics Inc (MAZE) stock price today?

The current price of MAZE is 51.055 USD — it has increased 13.3

What is Maze Therapeutics Inc (MAZE)'s business?

Maze Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in harnessing the power of human genetics and variant functionalization with its Maze Compass platform to develop small-molecule precision medicines for the treatment of renal, cardiovascular and related metabolic diseases, including obesity. The Compass platform has been purpose-built to inform all phases of drug discovery and development process through clinical trial design, advancing two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach to chronic kidney disease (CKD). Its lead program, MZE829, is an oral, small-molecule inhibitor of apolipoprotein L1, or APOL1, for the treatment of patients with APOL1 kidney disease, or AKD. Its second lead program, MZE782, is an oral, small-molecule inhibitor of the solute transporter SLC6A19, a novel CKD target.

What is the price predicton of MAZE Stock?

Wall Street analysts forecast MAZE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MAZE is52.00 USD with a low forecast of 46.00 USD and a high forecast of 60.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Maze Therapeutics Inc (MAZE)'s revenue for the last quarter?

Maze Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased -100.00

What is Maze Therapeutics Inc (MAZE)'s earnings per share (EPS) for the last quarter?

Maze Therapeutics Inc. EPS for the last quarter amounts to -0.66 USD, increased 1000.00

How many employees does Maze Therapeutics Inc (MAZE). have?

Maze Therapeutics Inc (MAZE) has 125 emplpoyees as of March 11 2026.

What is Maze Therapeutics Inc (MAZE) market cap?

Today MAZE has the market capitalization of 2.46B USD.