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KYTX Overview

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ET
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Intellectia

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High
9.740
Open
9.140
VWAP
9.39
Vol
1.20M
Mkt Cap
588.50M
Low
8.754
Amount
11.28M
EV/EBITDA(TTM)
--
Total Shares
60.80M
EV
345.47M
EV/OCF(TTM)
--
P/S(TTM)
--
Kyverna Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing cell therapies for patients with autoimmune diseases. The Company’s lead chimeric antigen receptor (CAR) T-cell therapy candidate, KYV-101, is advancing through clinical development with Phase II trials for stiff person syndrome and myasthenia gravis, and two ongoing multi-center Phase I/II trials for patients with lupus nephritis. KYV-101 is an autologous, fully human CD19 CAR T-cell product candidate incorporating highly potent CD28 co-stimulation. The Company is also harnessing investigator-initiated trials and other KYSA studies, including in multiple sclerosis and systemic sclerosis, to inform the next priority indications for the Company to advance into late-stage development. Its pipeline includes next generation CAR T-cell therapies in both autologous and allogeneic formats with properties intended to be well suited for use in B cell-driven autoimmune diseases.
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Events Timeline

(ET)
2026-06-22
08:31:00
Kyverna Therapeutics Appoints Ritesh Srivastava as Chief Legal and Compliance Officer
select
2026-06-03 (ET)
2026-06-03
08:30:00
Kyverna Therapeutics Updates COMPARE Trial Data
select
2026-05-18 (ET)
2026-05-18
08:10:00
Kyverna Therapeutics Appoints Greg Martini as CFO
select
2026-05-12 (ET)
2026-05-12
17:00:00
Kyverna Reports $39.7M Net Loss for Q1
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2026-05-04 (ET)
2026-05-04
08:10:00
Kyverna Therapeutics Appoints Nadia Dac as Chief Commercial Officer
select
2026-04-21 (ET)
2026-04-21
18:50:00
Kyverna Therapeutics Announces Positive Results from KYSA-8 Trial
select
2026-04-20 (ET)
2026-04-20
08:20:00
Kyverna Therapeutics Reports Positive Data from KYSA-6 Trial
select
2026-03-26 (ET)
2026-03-26
16:30:00
Kyverna Therapeutics Files $300M Mixed Securities Shelf
select

News

Fool
8.5
06-08Fool
Biopharma Investment Comparison: Kyverna vs. Vertex
  • Kyverna's Clinical Challenges: Kyverna Therapeutics focuses on developing cell therapies for autoimmune diseases, with its lead candidate KYV-101 yet to gain approval, reporting a net loss of $161.3 million in FY 2025, highlighting the high costs of R&D and clinical trial risks, leaving its future market success uncertain.
  • Vertex's Market Dominance: Vertex Pharmaceuticals holds a dominant position in the cystic fibrosis market, achieving $12 billion in revenue for FY 2025, a 9.6% increase, with a net income of nearly $4 billion, demonstrating strong demand for its established products and profitability.
  • Risk and Reward Trade-off: Kyverna faces risks due to its lack of revenue and high R&D expenses, while Vertex relies heavily on cystic fibrosis treatment revenue, creating concentration risk if the market is disrupted, necessitating careful consideration by investors based on their risk tolerance.
  • Future Growth Potential: While Kyverna has the potential to develop a breakthrough drug for Stiff-Person Syndrome, its market outlook remains unclear until regulatory approval is obtained; in contrast, Vertex shows a more robust growth outlook through continuous innovation and expansion into new treatment areas.
NASDAQ.COM
5.0
06-08NASDAQ.COM
Analyzing Biopharmaceutical Investment Choices
  • Financial Performance: Vertex Pharmaceuticals achieved $12 billion in revenue for FY 2025, reflecting a 9.6% increase year-over-year, with a net income of nearly $4 billion and a net margin of approximately 33%, indicating strong market position and profitability in the treatment sector.
  • R&D Risk Assessment: Kyverna Therapeutics, as a clinical-stage company, reported a net loss of $161.3 million in FY 2025 with no revenue, highlighting the high R&D costs associated with complex clinical trials and the uncertainty of future success.
  • Market Competition Dynamics: Vertex holds a near-monopoly in the cystic fibrosis market while expanding into other therapeutic areas, whereas Kyverna focuses on developing cell therapies for autoimmune diseases, facing significant market risks and competitive pressures.
  • Innovative Product Outlook: Kyverna's miv-cel has the potential to become a breakthrough drug for Stiff-Person Syndrome, and while there are currently no FDA-approved treatments, successful market entry could present substantial opportunities for the company.
NASDAQ.COM
9.0
06-04NASDAQ.COM
Kyverna Therapeutics Reports Phase 1 Data for miv-cel in Rheumatoid Arthritis
  • Clinical Trial Update: Kyverna Therapeutics presented updated Phase 1 data for miv-cel in treating ACPA-positive, treatment-refractory rheumatoid arthritis at the EULAR 2026 congress, demonstrating the therapy's efficacy and safety.
  • Significant Patient Response: Among the six patients receiving a single infusion of 100 million miv-cel CAR-T cells, 66.6% achieved an ACR70 response by week 36, indicating a substantial reduction in disease activity and showcasing the therapy's profound impact.
  • Immune System Reset: Post-treatment, there was a marked depletion of autoreactive CD19-positive B cells and plasmablasts, with rapid declines in disease-associated autoantibodies like ACPA, IgA, and IgM, indicating a complete immune reset achieved by the therapy.
  • Future Research Plans: Following the positive clinical data, Kyverna has initiated a Phase 2 trial and is advancing miv-cel in registrational studies for stiff person syndrome and generalized myasthenia gravis, highlighting the company's ongoing development potential in autoimmune diseases.
seekingalpha
5.0
05-18seekingalpha
Kyverna Appoints New CFO to Support Product Launch
  • Executive Change: Kyverna Therapeutics has appointed Greg Martini as CFO to prepare for the potential commercial launch of its autoimmune disease cell therapy candidate miv-cel, with Martini previously serving as SVP and CFO at Ironwood Pharmaceuticals.
  • Succession Plan: Martini succeeds Marc Grasso, who will remain with the company in a consulting role during the transition, ensuring stability and continuity amid leadership changes.
  • Product Advancement: Kyverna is advancing miv-cel, also known as KYV-101, aiming for its first approval in stiff person syndrome, indicating the company's strategic positioning in the autoimmune disease treatment landscape.
  • Market Outlook: As the BLA submission process for miv-cel progresses, Kyverna's market potential is expanding, particularly with positive clinical trial results in treating conditions like myasthenia gravis, laying a foundation for future growth.
seekingalpha
9.0
05-12seekingalpha
Kyverna Initiates Rolling BLA Process with FDA for miv-cel
  • BLA Process Initiation: Kyverna Therapeutics (KYTX) has commenced the rolling Biologics License Application (BLA) process for its autoimmune CAR T therapy, miv-cel, marking a significant advancement in treating stiff person syndrome.
  • Clinical Data Integration: The company has agreed with the FDA to include results from the KYSA-8 single-arm trial in the application, with the primary endpoint being the Timed 25-foot Walk (T2FW) test at 16 weeks, highlighting the focus on efficacy.
  • Market Expectations: Kyverna anticipates launching miv-cel in 2027, which, if successful, could present substantial market opportunities, particularly in the rare disease space of stiff person syndrome.
  • Additional Research Progress: In addition to stiff person syndrome, miv-cel is also under investigation for myasthenia gravis, further demonstrating its potential across various autoimmune diseases and bolstering investor confidence in the company.
seekingalpha
9.5
05-12seekingalpha
Kyverna Therapeutics Q1 Earnings Beat Expectations
  • Earnings Highlights: Kyverna Therapeutics reported a Q1 GAAP EPS of -$0.66, beating expectations by $0.09, indicating a positive trend in financial performance despite ongoing losses.
  • Cash Reserves: As of March 31, 2026, Kyverna holds $236.4 million in cash, cash equivalents, and marketable securities, providing ample funding support and ensuring a cash runway into 2028, which enhances operational stability.
  • Clinical Progress: Kyverna's mid-stage trial for myasthenia gravis therapy yielded positive data, with deep responses noted despite a small sample size, potentially attracting increased investor interest in future treatment options.
  • Funding Strategy: The company has filed for a $300 million mixed securities shelf to support ongoing R&D and market initiatives, reflecting confidence in future growth and strategic planning.
Wall Street analysts forecast KYTX stock price to rise
5 Analyst Rating
Wall Street analysts forecast KYTX stock price to rise
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
20.00
Averages
29.50
High
33.00
Current: 0.000
sliders
Low
20.00
Averages
29.50
High
33.00
H.C. Wainwright
Mitchell Kapoor
Buy
maintain
$20 -> $25
AI Analysis
2026-05-15
Reason
H.C. Wainwright
Mitchell Kapoor
Price Target
$20 -> $25
AI Analysis
2026-05-15
maintain
Buy
Reason
H.C. Wainwright analyst Mitchell Kapoor raised the firm's price target on Kyverna Therapeutics to $25 from $20 and keeps a Buy rating on the shares. Following a discussion with management, the firm added stiff person syndrome into Kyverna's model ahead of a 2027 miv-cel launch. It assigns a 70% probability of approval and $800M in peak sales.
JPMorgan
Brian Cheng
Overweight
maintain
$30 -> $29
2026-05-13
Reason
JPMorgan
Brian Cheng
Price Target
$30 -> $29
2026-05-13
maintain
Overweight
Reason
JPMorgan analyst Brian Cheng lowered the firm's price target on Kyverna Therapeutics to $29 from $30 and keeps an Overweight rating on the shares. The firm updated the company's model post the Q1 report. It views Kyverna's progress around the rolling application in stiff person syndrome positively.
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Valuation Metrics

The current forward P/E ratio for Kyverna Therapeutics Inc (KYTX.O) is 0.00, compared to its 5-year average forward P/E of -2.51. For a more detailed relative valuation and DCF analysis to assess Kyverna Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.51
Current PE
0.00
Overvalued PE
-0.21
Undervalued PE
-4.81

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.89
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.98
Undervalued EV/EBITDA
-3.77

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
7.17
Current PS
31.65
Overvalued PS
21.27
Undervalued PS
-6.93

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+57.10%
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Frequently Asked Questions

What is Kyverna Therapeutics Inc (KYTX) stock price today?

The current price of KYTX is 9.68 USD — it has increased 5.68

What is Kyverna Therapeutics Inc (KYTX)'s business?

Kyverna Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing cell therapies for patients with autoimmune diseases. The Company’s lead chimeric antigen receptor (CAR) T-cell therapy candidate, KYV-101, is advancing through clinical development with Phase II trials for stiff person syndrome and myasthenia gravis, and two ongoing multi-center Phase I/II trials for patients with lupus nephritis. KYV-101 is an autologous, fully human CD19 CAR T-cell product candidate incorporating highly potent CD28 co-stimulation. The Company is also harnessing investigator-initiated trials and other KYSA studies, including in multiple sclerosis and systemic sclerosis, to inform the next priority indications for the Company to advance into late-stage development. Its pipeline includes next generation CAR T-cell therapies in both autologous and allogeneic formats with properties intended to be well suited for use in B cell-driven autoimmune diseases.

What is the price predicton of KYTX Stock?

Wall Street analysts forecast KYTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for KYTX is29.50 USD with a low forecast of 20.00 USD and a high forecast of 33.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Kyverna Therapeutics Inc (KYTX)'s revenue for the last quarter?

Kyverna Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Kyverna Therapeutics Inc (KYTX)'s earnings per share (EPS) for the last quarter?

Kyverna Therapeutics Inc. EPS for the last quarter amounts to -0.66 USD, decreased -35.92

How many employees does Kyverna Therapeutics Inc (KYTX). have?

Kyverna Therapeutics Inc (KYTX) has 134 emplpoyees as of July 08 2026.

What is Kyverna Therapeutics Inc (KYTX) market cap?

Today KYTX has the market capitalization of 588.50M USD.