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KYTX Overview

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0.000(0.000%)Aft-market
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0.000
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ET
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Intellectia

Loading chart...

High
10.280
Open
10.280
VWAP
10.09
Vol
616.82K
Mkt Cap
619.22M
Low
9.750
Amount
6.22M
EV/EBITDA(TTM)
--
Total Shares
60.53M
EV
371.68M
EV/OCF(TTM)
--
P/S(TTM)
--
Kyverna Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing cell therapies for patients with autoimmune diseases. The Company’s lead chimeric antigen receptor (CAR) T-cell therapy candidate, KYV-101, is advancing through clinical development with Phase II trials for stiff person syndrome and myasthenia gravis, and two ongoing multi-center Phase I/II trials for patients with lupus nephritis. KYV-101 is an autologous, fully human CD19 CAR T-cell product candidate incorporating highly potent CD28 co-stimulation. The Company is also harnessing investigator-initiated trials and other KYSA studies, including in multiple sclerosis and systemic sclerosis, to inform the next priority indications for the Company to advance into late-stage development. Its pipeline includes next generation CAR T-cell therapies in both autologous and allogeneic formats with properties intended to be well suited for use in B cell-driven autoimmune diseases.
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Events Timeline

(ET)
2026-05-12
17:00:00
Kyverna Reports $39.7M Net Loss for Q1
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2026-05-04 (ET)
2026-05-04
08:10:00
Kyverna Therapeutics Appoints Nadia Dac as Chief Commercial Officer
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2026-04-21 (ET)
2026-04-21
18:50:00
Kyverna Therapeutics Announces Positive Results from KYSA-8 Trial
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2026-04-20 (ET)
2026-04-20
08:20:00
Kyverna Therapeutics Reports Positive Data from KYSA-6 Trial
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2026-03-26 (ET)
2026-03-26
16:30:00
Kyverna Therapeutics Files $300M Mixed Securities Shelf
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2026-03-26
16:10:00
Kyverna Reports $279.3M in Cash and Securities
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2026-02-24 (ET)
2026-02-24
08:30:00
Kyverna Therapeutics Appoints New Board Members
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2026-02-03 (ET)
2026-02-03
08:30:00
Kyverna Therapeutics Appoints Mayo Pujols as CTO
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2026-01-12 (ET)
2026-01-12
08:30:00
Kyverna Therapeutics Updates Strategic Priorities, Plans BLA Submission in 2026
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News

seekingalpha
9.0
05-12seekingalpha
PinnedKyverna Initiates Rolling BLA Process with FDA for miv-cel
  • BLA Process Initiation: Kyverna Therapeutics (KYTX) has commenced the rolling Biologics License Application (BLA) process for its autoimmune CAR T therapy, miv-cel, marking a significant advancement in treating stiff person syndrome.
  • Clinical Data Integration: The company has agreed with the FDA to include results from the KYSA-8 single-arm trial in the application, with the primary endpoint being the Timed 25-foot Walk (T2FW) test at 16 weeks, highlighting the focus on efficacy.
  • Market Expectations: Kyverna anticipates launching miv-cel in 2027, which, if successful, could present substantial market opportunities, particularly in the rare disease space of stiff person syndrome.
  • Additional Research Progress: In addition to stiff person syndrome, miv-cel is also under investigation for myasthenia gravis, further demonstrating its potential across various autoimmune diseases and bolstering investor confidence in the company.
seekingalpha
9.5
05-12seekingalpha
Kyverna Therapeutics Q1 Earnings Beat Expectations
  • Earnings Highlights: Kyverna Therapeutics reported a Q1 GAAP EPS of -$0.66, beating expectations by $0.09, indicating a positive trend in financial performance despite ongoing losses.
  • Cash Reserves: As of March 31, 2026, Kyverna holds $236.4 million in cash, cash equivalents, and marketable securities, providing ample funding support and ensuring a cash runway into 2028, which enhances operational stability.
  • Clinical Progress: Kyverna's mid-stage trial for myasthenia gravis therapy yielded positive data, with deep responses noted despite a small sample size, potentially attracting increased investor interest in future treatment options.
  • Funding Strategy: The company has filed for a $300 million mixed securities shelf to support ongoing R&D and market initiatives, reflecting confidence in future growth and strategic planning.
NASDAQ.COM
9.0
04-22NASDAQ.COM
Kyverna Therapeutics Reports Positive Phase 2 Trial Results for Miv-cel in Stiff Person Syndrome
  • Trial Success: Kyverna Therapeutics' KYSA-8 trial demonstrated a statistically significant median improvement of 46% in the Timed 25-Foot Walk (T25FW) at 16 weeks, indicating the efficacy of miv-cel in treating Stiff Person Syndrome (SPS) and enhancing patient mobility.
  • Significant Patient Improvement: Among treated patients, 81% achieved clinically meaningful improvements of 20% or more, with nearly one-third walking at healthy adult speeds by week 16, reflecting the positive impact of the therapy on functional independence.
  • Good Safety Profile: Miv-cel exhibited a well-tolerated safety profile, with four patients experiencing Grade 3/4 neutropenia, a manageable side effect associated with CAR T-cell therapy, and all serious treatment-related adverse events resolved fully without lasting effects.
  • Future Outlook: The trial results will be presented at the American Academy of Neurology Annual Meeting in Chicago, which is expected to further enhance KYTX's market performance and increase investor interest in the biopharmaceutical sector.
stocktwits
9.0
04-22stocktwits
Kyverna's CAR-T Therapy Shows Significant Mobility Improvements in Clinical Trial
  • Trial Results: At the American Academy of Neurology Annual Meeting, Kyverna reported that 81% of patients in their phase-2 trial achieved clinically meaningful mobility improvements at 16 weeks, highlighting the efficacy of their CAR-T cell therapy.
  • Positive Patient Response: Among the 26 patients who had not responded well to standard therapies, two-thirds no longer required walking aids after receiving a single dose of miv-cel, and all patients were able to discontinue chronic immunotherapies, demonstrating the therapy's significant impact.
  • Manageable Side Effects: Miv-cel was generally well-tolerated, with the most common side effect being a temporary drop in neutrophil counts that was manageable, indicating the therapy's feasibility in terms of safety.
  • Broad Market Potential: Kyverna plans to submit a biologics license application to the FDA, and if approved, it would be the first treatment for stiff person syndrome, with a total addressable market exceeding $80 billion, attracting significant investor interest.
stocktwits
4.5
04-22stocktwits
US Stock Futures Edge Up Amid Mixed Market Sentiment
  • Market Sentiment Fluctuates: Following President Trump's announcement of a ceasefire extension with Iran, US stock index futures edged higher, with Nasdaq 100 futures up 0.68%, S&P 500 futures up 0.53%, and Dow futures up 0.47%, indicating cautious optimism among investors regarding future developments.
  • Market Close Performance: Despite the uptick in futures, the S&P 500, Dow Jones Industrial Average, and Nasdaq Composite all declined about 0.6% at Monday's close, reflecting ongoing uncertainty surrounding peace negotiations that may impact short-term investment decisions.
  • Oil Price Volatility: In Tuesday's trading, WTI crude futures fell 0.07% to $89.61 per barrel, while Brent crude futures dropped 0.02% to $98.46 per barrel, indicating market concerns over global economic prospects that could affect energy-related stocks.
  • Stock Movements: Poet Technologies saw its shares rise after the CFO's dismissal, Navitas Semiconductor gained over 2% following the appointment of a new independent director, and Kyverna Therapeutics surged 29% after reporting positive results in a clinical trial, highlighting market interest in specific tech and biotech companies.
Newsfilter
8.5
04-21Newsfilter
Kyverna's miv-cel Shows Significant Improvement in Stiff Person Syndrome
  • Clinical Trial Results: Kyverna Therapeutics' miv-cel demonstrated significant clinical improvements in the KYSA-8 registrational trial for Stiff Person Syndrome (SPS), with a 46% improvement in T25FW at 16 weeks and 81% of patients achieving clinically meaningful functional gains, marking a fundamental shift in treatment paradigms.
  • New Immunotherapy Option: All 26 patients discontinued chronic immunotherapies after a single dose of miv-cel, showcasing the therapy's potential to enhance patient quality of life and possibly become the first approved treatment for SPS.
  • Good Safety Profile: Miv-cel exhibited a favorable safety profile with no high-grade cytokine release syndrome or neurotoxicity observed, and most adverse events were manageable, indicating its suitability for outpatient administration and enhancing its market prospects.
  • Future Outlook: Kyverna plans to submit a Biologics License Application (BLA) and is confident in miv-cel's potential for other neurological autoimmune diseases, suggesting that this therapy may play a significant role in broader indications.
Wall Street analysts forecast KYTX stock price to rise
5 Analyst Rating
Wall Street analysts forecast KYTX stock price to rise
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
20.00
Averages
29.50
High
33.00
Current: 0.000
sliders
Low
20.00
Averages
29.50
High
33.00
JPMorgan
Brian Cheng
Overweight
maintain
$30 -> $29
AI Analysis
2026-05-13
New
Reason
JPMorgan
Brian Cheng
Price Target
$30 -> $29
AI Analysis
2026-05-13
New
maintain
Overweight
Reason
JPMorgan analyst Brian Cheng lowered the firm's price target on Kyverna Therapeutics to $29 from $30 and keeps an Overweight rating on the shares. The firm updated the company's model post the Q1 report. It views Kyverna's progress around the rolling application in stiff person syndrome positively.
Wells Fargo
Overweight
maintain
$31 -> $33
2025-12-16
Reason
Wells Fargo
Price Target
$31 -> $33
2025-12-16
maintain
Overweight
Reason
Wells Fargo raised the firm's price target on Kyverna Therapeutics to $33 from $31 and keeps an Overweight rating on the shares. The firm notes that mivocabtagene-autoleucel's stiff person syndrome data is in line with its bull case and it believes shares should trade up into the mid-teens on the data. Wells thinks mivocabtagene-autoleucel could potentially benefit from priority review/CNPV given the high unmet need in stiff person syndrome.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for KYTX
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Valuation Metrics

The current forward P/E ratio for Kyverna Therapeutics Inc (KYTX.O) is 0.00, compared to its 5-year average forward P/E of -2.51. For a more detailed relative valuation and DCF analysis to assess Kyverna Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.51
Current PE
0.00
Overvalued PE
-0.21
Undervalued PE
-4.81

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.89
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.98
Undervalued EV/EBITDA
-3.77

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
5.46
Current PS
48.76
Overvalued PS
18.27
Undervalued PS
-7.35

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Whales Holding KYTX

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Insight Venture Management, LLC
Holding
KYTX
+16.61%
3M Return

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Frequently Asked Questions

What is Kyverna Therapeutics Inc (KYTX) stock price today?

The current price of KYTX is 10.23 USD — it has decreased -1.06

What is Kyverna Therapeutics Inc (KYTX)'s business?

Kyverna Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing cell therapies for patients with autoimmune diseases. The Company’s lead chimeric antigen receptor (CAR) T-cell therapy candidate, KYV-101, is advancing through clinical development with Phase II trials for stiff person syndrome and myasthenia gravis, and two ongoing multi-center Phase I/II trials for patients with lupus nephritis. KYV-101 is an autologous, fully human CD19 CAR T-cell product candidate incorporating highly potent CD28 co-stimulation. The Company is also harnessing investigator-initiated trials and other KYSA studies, including in multiple sclerosis and systemic sclerosis, to inform the next priority indications for the Company to advance into late-stage development. Its pipeline includes next generation CAR T-cell therapies in both autologous and allogeneic formats with properties intended to be well suited for use in B cell-driven autoimmune diseases.

What is the price predicton of KYTX Stock?

Wall Street analysts forecast KYTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for KYTX is29.50 USD with a low forecast of 20.00 USD and a high forecast of 33.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Kyverna Therapeutics Inc (KYTX)'s revenue for the last quarter?

Kyverna Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Kyverna Therapeutics Inc (KYTX)'s earnings per share (EPS) for the last quarter?

Kyverna Therapeutics Inc. EPS for the last quarter amounts to -0.66 USD, decreased -35.92

How many employees does Kyverna Therapeutics Inc (KYTX). have?

Kyverna Therapeutics Inc (KYTX) has 134 emplpoyees as of May 13 2026.

What is Kyverna Therapeutics Inc (KYTX) market cap?

Today KYTX has the market capitalization of 619.22M USD.