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JANX Overview

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ET
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Intellectia

Loading chart...

High
14.070
Open
13.960
VWAP
13.92
Vol
102.29K
Mkt Cap
855.90M
Low
13.740
Amount
1.42M
EV/EBITDA(TTM)
--
Total Shares
60.83M
EV
-110.67M
EV/OCF(TTM)
--
P/S(TTM)
87.19
Janux Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing tumor-activated immunotherapies for cancer. It has developed two bispecific platforms: Tumor Activated T Cell Engagers (TRACTr) and Tumor Activated Immunomodulators (TRACIr). The TRACTr platform produces T cell engagers (TCEs) with a tumor antigen-binding domain and a CD3 T cell binding domain, while the TRACIr platform produces bispecifics with a tumor antigen-binding domain and a costimulatory CD28 binding domain. Its clinical candidates include JANX007 and JANX008. JANX007 is a prostate-specific membrane antigen (PSMA-TRACTr) designed to target PSMA, a protein expressed in prostate cancer tumors and the vasculature of other tumors. JANX008 is an epidermal growth factor receptor (EGFR-TRACTr), being studied for the treatment of multiple solid cancers, including colorectal cancer, squamous cell carcinoma of the head and neck, non-small cell lung cancer, and renal cell carcinoma.
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Events Timeline

(ET)
2026-02-26
16:20:00
Janux Announces Clinical Progress and Collaboration
select
2026-02-17 (ET)
2026-02-17
08:00:00
Janux Therapeutics Doses First Participant in JANX011 Clinical Trial
select
2026-01-26 (ET)
2026-01-26
07:10:00
Janux Therapeutics Appoints William Go as Chief Medical Officer
select
2026-01-22 (ET)
2026-01-22
07:30:00
Janux Enters Exclusive Global Collaboration with Bristol Myers
select

News

NASDAQ.COM
9.5
02-27NASDAQ.COM
Janux Therapeutics Reports Increased Q4 Losses
  • Earnings Overview: Janux Therapeutics reported a fourth-quarter loss of $42.40 million, translating to a loss of $0.51 per share, which is a significant increase from last year's loss of $20.22 million or $0.36 per share, indicating heightened pressure on the company's profitability.
  • Year-over-Year Comparison: The loss increased by 109% compared to the same period last year, highlighting intensified challenges in cost control and revenue growth, which may impact future financing capabilities and investor confidence.
  • Market Reaction: The larger-than-expected loss may lead investors to adopt a cautious outlook on the company's future financial performance, resulting in increased stock price volatility and affecting the company's standing in the capital markets.
  • Strategic Implications: Ongoing losses may prompt the company to reassess its R&D and operational strategies to seek more effective cost management and revenue growth pathways, thereby ensuring survival and growth in the highly competitive biopharmaceutical industry.
seekingalpha
9.5
02-26seekingalpha
Janux Therapeutics Q4 Earnings Beat Expectations
  • Earnings Surprise: Janux Therapeutics reported a Q4 GAAP EPS of -$0.51, beating expectations by $0.16, indicating some financial resilience despite ongoing losses.
  • Cash Reserves Decline: As of December 31, 2025, Janux's cash and cash equivalents totaled $966.6 million, down from $1.03 billion a year earlier, reflecting significant operational and R&D expenditures.
  • Rating Downgrade Impact: Following the latest Phase 1 JANX007 data update, Janux's stock rating was downgraded to 'Hold', which may affect investor confidence and lead to short-term stock price volatility as the market reassesses its 'best-in-class' status.
  • Partnership Progress: Bristol Myers has inked a licensing deal with Janux for cancer therapy, indicating continued market interest in Janux's technology, which could provide new revenue streams and enhance its competitive position.
Benzinga
7.5
01-22Benzinga
Janux Therapeutics and Bristol Myers Squibb Sign $800 Million Collaboration Agreement
  • Collaboration Agreement: Janux Therapeutics has entered into an exclusive worldwide license agreement with Bristol Myers Squibb, receiving up to $50 million in upfront and near-term milestone payments, with potential total payments reaching approximately $800 million, significantly enhancing its capabilities in developing tumor immunotherapies.
  • Clinical Development Support: The collaboration allows Janux to complete preclinical development up to Investigational New Drug (IND) submission, while Bristol Myers Squibb will take charge of subsequent development and commercialization, expected to accelerate the market introduction of new drugs.
  • Positive Market Reaction: Following the announcement of the agreement, Janux's stock rose by 7.69% to $14.29, despite a 66.97% decline over the past 12 months, indicating that the collaboration is seen as a strong validation of its tumor-activated platform, potentially improving investor confidence.
  • Optimistic Analyst Ratings: Although Clear Street downgraded its rating to Hold with a target price of $12.00, the overall analyst consensus remains a Buy with an average target price of $61.76, reflecting market confidence in Janux's future development.
stocktwits
7.5
01-22stocktwits
Janux Therapeutics (JANX) Partners with Bristol Myers Squibb for Tumor-Activated Therapy Development
  • Strategic Collaboration: Janux Therapeutics has entered a partnership with Bristol Myers Squibb to focus on a yet-to-be-disclosed solid tumor target across multiple cancer types, aiming to expand treatment options for patients globally and enhance the company's market position in oncology.
  • Development Management Division: Under the agreement, Janux will handle preclinical development through IND submission, while Bristol Myers Squibb will hold the IND and oversee subsequent clinical development and global commercialization, ensuring efficient resource utilization and specialized management.
  • Positive Market Reaction: Following the announcement, Janux Therapeutics' stock traded over 8% higher in Thursday's premarket, reflecting market optimism regarding the collaboration's prospects, which may enhance the company's future fundraising capabilities and investor confidence.
  • Global Commercialization Potential: This partnership not only strengthens Janux's R&D capabilities in oncology but also provides Bristol Myers Squibb with a new product line, expected to drive both companies' competitiveness and market share in the global market.
NASDAQ.COM
7.5
01-22NASDAQ.COM
Janux Therapeutics (JANX) Partners with Bristol Myers Squibb for $50M Collaboration on Solid Tumor Therapy
  • Collaboration Agreement: Janux Therapeutics has signed an exclusive worldwide license agreement with Bristol Myers Squibb to advance a novel therapy for solid tumors, which is expected to significantly enhance both companies' market competitiveness in oncology.
  • Financial Support: Under the agreement, Janux will receive up to $50 million in upfront and near-term milestone payments, along with approximately $800 million in development, regulatory, and commercial milestones, thereby strengthening the company's financial flexibility.
  • Technology Integration: Janux's proprietary tumor-activated platforms (TRACTr, TRACIr, and ARM) will be combined with Bristol Myers Squibb's clinical development expertise, which is anticipated to accelerate the clinical progress of new therapies and improve treatment outcomes, further solidifying its position in the tumor immunotherapy space.
  • Clinical Trial Involvement: Janux will remain actively involved in the first Phase 1 clinical study, ensuring the efficacy and safety of its technology, which not only helps enhance the company's reputation but may also pave the way for future product development.
seekingalpha
7.5
01-22seekingalpha
Janux Therapeutics Secures Exclusive License Agreement with Bristol Myers Squibb, Potential Earnings Up to $800 Million
  • Collaboration Agreement: Janux Therapeutics has entered into an exclusive worldwide license agreement with Bristol Myers Squibb, focusing on developing a tumor antigen therapeutic for various cancer types, which is expected to significantly enhance both companies' market competitiveness in oncology.
  • Financial Support: Under the agreement, Janux is eligible for up to $50 million in upfront and near-term milestone payments, along with approximately $800 million in development, regulatory, and commercial milestones, ensuring robust funding for future research and development.
  • R&D Responsibility: Janux will handle preclinical development up to the submission of an Investigational New Drug (IND) application, with the successful completion of this phase laying the groundwork for Bristol Myers Squibb's clinical development and commercialization, highlighting the close collaboration between the two firms.
  • Market Potential: This partnership not only provides Janux with substantial financial backing but also enhances its influence in the cancer treatment market through collaboration with Bristol Myers Squibb, potentially accelerating the market entry of new therapies.
Wall Street analysts forecast JANX stock price to rise
16 Analyst Rating
Wall Street analysts forecast JANX stock price to rise
15 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
25.00
Averages
55.25
High
150.00
Current: 0.000
sliders
Low
25.00
Averages
55.25
High
150.00
Truist
Buy
downgrade
$100 -> $80
AI Analysis
2026-03-03
Reason
Truist
Price Target
$100 -> $80
AI Analysis
2026-03-03
downgrade
Buy
Reason
Truist lowered the firm's price target on Janux Therapeutics to $80 from $100 and keeps a Buy rating on the shares. The firm is updating its model after Q4 earnings and recent prostate cancer developments, slightly lowering its max penetration for JANX007 due to new entrants while maintaining its probabilit of success assumptions, the analyst tells investors in a research note.
Cantor Fitzgerald
Overweight
downgrade
$150 -> $100
2026-02-27
Reason
Cantor Fitzgerald
Price Target
$150 -> $100
2026-02-27
downgrade
Overweight
Reason
Cantor Fitzgerald lowered the firm's price target on Janux Therapeutics to $100 from $150 and keeps an Overweight rating on the shares. Janux reported Q4 results and outlined 2026 guidance for clinical updates across its TRACTr and ARM platforms, emphasizing continued execution, the analyst tells investors in a research note. Management improved its narrative, clarifying data presentation amid intensifying competitive dynamics, especially from China, the firm says.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for JANX
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Valuation Metrics

The current forward P/E ratio for Janux Therapeutics Inc (JANX.O) is -4.73, compared to its 5-year average forward P/E of -15.37. For a more detailed relative valuation and DCF analysis to assess Janux Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-15.37
Current PE
-4.73
Overvalued PE
-4.27
Undervalued PE
-26.46

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-8.08
Current EV/EBITDA
0.75
Overvalued EV/EBITDA
0.57
Undervalued EV/EBITDA
-16.74

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
511.27
Current PS
732.14
Overvalued PS
961.61
Undervalued PS
60.94

Financials

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Whales Holding JANX

R
RA Capital Management, L.P.
Holding
JANX
+4.57%
3M Return
N
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.
Holding
JANX
+3.90%
3M Return
T
TCG Crossover Management, LLC
Holding
JANX
+1.37%
3M Return
C
Cormorant Asset Management, LP
Holding
JANX
+0.42%
3M Return
L
Logos Global Management, L.P.
Holding
JANX
-0.20%
3M Return
R
Readystate Asset Management LP
Holding
JANX
-0.54%
3M Return

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Frequently Asked Questions

What is Janux Therapeutics Inc (JANX) stock price today?

The current price of JANX is 13.95 USD — it has decreased -0.85

What is Janux Therapeutics Inc (JANX)'s business?

Janux Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing tumor-activated immunotherapies for cancer. It has developed two bispecific platforms: Tumor Activated T Cell Engagers (TRACTr) and Tumor Activated Immunomodulators (TRACIr). The TRACTr platform produces T cell engagers (TCEs) with a tumor antigen-binding domain and a CD3 T cell binding domain, while the TRACIr platform produces bispecifics with a tumor antigen-binding domain and a costimulatory CD28 binding domain. Its clinical candidates include JANX007 and JANX008. JANX007 is a prostate-specific membrane antigen (PSMA-TRACTr) designed to target PSMA, a protein expressed in prostate cancer tumors and the vasculature of other tumors. JANX008 is an epidermal growth factor receptor (EGFR-TRACTr), being studied for the treatment of multiple solid cancers, including colorectal cancer, squamous cell carcinoma of the head and neck, non-small cell lung cancer, and renal cell carcinoma.

What is the price predicton of JANX Stock?

Wall Street analysts forecast JANX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for JANX is55.25 USD with a low forecast of 25.00 USD and a high forecast of 150.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Janux Therapeutics Inc (JANX)'s revenue for the last quarter?

Janux Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Janux Therapeutics Inc (JANX)'s earnings per share (EPS) for the last quarter?

Janux Therapeutics Inc. EPS for the last quarter amounts to -0.51 USD, increased 41.67

How many employees does Janux Therapeutics Inc (JANX). have?

Janux Therapeutics Inc (JANX) has 109 emplpoyees as of March 11 2026.

What is Janux Therapeutics Inc (JANX) market cap?

Today JANX has the market capitalization of 855.90M USD.