IONS Forecast — Price Prediction for 2025. Should I Buy IONS?
1-Day-Price-Prediction
-0.63%
1-Week Prediction
-2.91%
1-Month Prediction
-1.54%
2026 Prediction
-63.83%
2030 Prediction
-60.47%
Based on our advanced algorithm, we predict that IONS stock price will experience significant movement in the coming periods. Our 1-day prediction estimates a price of $79.26, while the 1-week outlook suggests a value of $77.44. For the 1-month forecast, we project a price of $78.53. Looking further ahead, our 2026 projection estimates a value of $28.85, with a long-term 2030 forecast reaching $31.53. Stay informed and make strategic decisions with our data-driven insights!
Should I Buy Ionis Pharmaceuticals Inc Stock?
Based on our evaluation of the five key dimensions—Technical Signals, Moving Average trends, Short Sell Data, Similar Chart Pattern Matching and Seasonality Analysis—we have identified the following insights. IONS has several positive signals and is within a rising trend, so we believe it will perform strongly in the next couple of days or weeks. We therefore hold a positive evaluation of this stock. Our analysis conclusion for this stock is a Strong Buy candidate.
IONS stock price ended at $79.76 on Monday, after losing-1.31%
The Ionis Pharmaceuticals Inc stock price decreased by -1.31% on the last trading day (15 Dec 2025), dropping from 80.35 to 79.76. Throughout the last trading session, the stock experienced a fluctuation of 2.13% , ranging from a day low of $79.31 to a day high of 81. The price has declined in 7 of the last 10 days, resulting in a total change of -2.72% during this period. On the last day, trading volume increase by 508.73K shares, with the falling prices. This could serve as an early warning, indicating that risk may slightly increase in the coming days. In total, 1.98M shares were traded, amounting to approximately 158.56M.
IONS Technical Signals
IONS(Ionis Pharmaceuticals Inc Corp) has 3 buy signals and 2 sell signals now. The current trend is consolidation starting from 2025-12-10. The total price change during this trend is +1.44%. Recently, the price has dropped while volume increased, indicating a strong bearish signal. The average turnover of IONS over the last 5 trading days is 159.03M. Overall, the technical indicator signals lean more toward a Neutral outlook in the mid-term.
IONS Moving Average Analysis
Ionis Pharmaceuticals Inc's overall moving average trend leans more bullish as of Tuesday, December 16, 2025, with 0 negative signals and 4 positive signal. In the mid-term, the SMA_20 being above the SMA_60 signals a strong bullish trend. There will be some resistance from the lines at $84.24, and $86.47. A break-up above any of these levels will issue buy signals. There will be some support from the lines at $77.05, and $74.83. A break-down below any of these levels will issue sell signals.
IONS Short Selling Analysis
The short sale ratio of Ionis Pharmaceuticals Inc(IONS) as of 10 Dec 2025 is 29.11%, rising from last trading day. With increasing price from 78.86 to 78.63. The short sell activity indicate that short sellers may be anticipating further declines.
Technical Signal
Technical Signals Summary
Sell
2
Buy
3
Moving Average
Swing
Positive
Stock Price Above SMA_5
Short Term
Positive
SMA_5 Above SMA_20
Mid Term
Positive
SMA_20 Above SMA_60
Long Term
Positive
SMA_60 Above SMA_200
Short Selling
Close Price
Short Sale Ratio
Short Sale Volume
3 Bullish Signals
3 Bullish Signals
When Value satisfies Signal, Indicator signals Bullish
Indicators
Signal
Value
Meaning
Indicators
Signal
Value
Meaning
Awesome Oscillator (5, 34)
AO_5_34 > 0
3.182
Bullish
Moving Average Convergence Divergence (12, 26, 9)
MACD_12_26_9 > 0
1.862
Bullish
Stochastic RSI %K (14, 14, 3, 3)
STOCHRSIk_14_14_3_3 < 20
19.009
Bullish
2 Bearish Signals
2 Bearish Signals
When Value satisfies Signal, Indicator signals Bearish
Indicators
Signal
Value
Meaning
Indicators
Signal
Value
Meaning
Momentum (10 days)
MOM_10 < 0
-2.23
Bearish
Moving Average
Price crosses below 10-day SMA
--
Bearish
IONS Stock Forecast
2026
2027
2028
2029
2030
2031
2032
2033
2034
2035
Month
Min. Price
Avg. Price
Max. Price
Potential ROI
Jan 2026
$31.55
$37.15
$43.43
-7.12%
Feb 2026
$34.95
$35.08
$36.50
-12.29%
Mar 2026
$28.58
$33.61
$41.78
-15.96%
Apr 2026
$30.67
$36.10
$38.96
-9.74%
May 2026
$28.21
$33.26
$35.09
-16.85%
Jun 2026
$32.54
$37.15
$43.89
-7.12%
Jul 2026
$30.96
$37.15
$42.41
-7.12%
Aug 2026
$31.42
$31.70
$35.67
-20.74%
Sep 2026
$23.56
$26.70
$27.28
-33.26%
Oct 2026
$29.39
$33.40
$37.32
-16.50%
Nov 2026
$26.88
$30.96
$35.84
-22.60%
Dec 2026
$20.89
$28.85
$34.91
-27.88%
In 2026, Ionis Pharmaceuticals Inc (IONS) is anticipated to change hands in a trading channel between $20.89 and $43.89.
Ionis Pharmaceuticals Inc Stock Forecast 2026
Jan 2026: IONS Stock Forecast
Potential ROI: -7.12%
In Jan 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $37.15. The price is predicted to fluctuate between a low of $31.55 and a high of $43.43.
Feb 2026: IONS Stock Forecast
Potential ROI: -12.29%
In Feb 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $35.08. The price is predicted to fluctuate between a low of $34.95 and a high of $36.50.
Mar 2026: IONS Stock Forecast
Potential ROI: -15.96%
In Mar 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $33.61. The price is predicted to fluctuate between a low of $28.58 and a high of $41.78.
Apr 2026: IONS Stock Forecast
Potential ROI: -9.74%
In Apr 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $36.10. The price is predicted to fluctuate between a low of $30.67 and a high of $38.96.
May 2026: IONS Stock Forecast
Potential ROI: -16.85%
In May 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $33.26. The price is predicted to fluctuate between a low of $28.21 and a high of $35.09.
Jun 2026: IONS Stock Forecast
Potential ROI: -7.12%
In Jun 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $37.15. The price is predicted to fluctuate between a low of $32.54 and a high of $43.89.
Jul 2026: IONS Stock Forecast
Potential ROI: -7.12%
In Jul 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $37.15. The price is predicted to fluctuate between a low of $30.96 and a high of $42.41.
Aug 2026: IONS Stock Forecast
Potential ROI: -20.74%
In Aug 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $31.70. The price is predicted to fluctuate between a low of $31.42 and a high of $35.67.
Sep 2026: IONS Stock Forecast
Potential ROI: -33.26%
In Sep 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $26.70. The price is predicted to fluctuate between a low of $23.56 and a high of $27.28.
Oct 2026: IONS Stock Forecast
Potential ROI: -16.50%
In Oct 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $33.40. The price is predicted to fluctuate between a low of $29.39 and a high of $37.32.
Nov 2026: IONS Stock Forecast
Potential ROI: -22.60%
In Nov 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $30.96. The price is predicted to fluctuate between a low of $26.88 and a high of $35.84.
Dec 2026: IONS Stock Forecast
Potential ROI: -27.88%
In Dec 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $28.85. The price is predicted to fluctuate between a low of $20.89 and a high of $34.91.
IONS Price Prediction & Forecast by Similar Chart Analysis
Based on historical patterns and backtesting of stocks with similar movements to Ionis Pharmaceuticals Inc(IONS), our algorithm predicts IONS's 1-month price at $80.67, with an -0.19%downwardshift. Using a similarity score up to 97.87%and other factors, This forecast updates weekly, adjusting for significant deviations.
Similar Chart
The price prediction chart for Ionis Pharmaceuticals Inc (IONS.O) stock, as of Sunday, December 14, 2025 , forecasts a -0.19% change over the next month, based on its high correlation with ALLT.O stock patterns. The similarity between their price movements over the analyzed periods is 97.87%. The right panel lists other stocks with similar price patterns. This prediction is updated every week.
IONS
No data
ALLT
Down: -0.19%Similarity: 97.87%
Name
Similarity
Up/Down
ALLT.O
97.87%
-0.19%
SSSS.O
97.13%
+2.87%
OPK.O
97.12%
+5.60%
VKTX.O
97.05%
-10.16%
SHW.N
96.93%
-2.42%
FITB.O
96.93%
+3.55%
DSGX.O
96.83%
+3.82%
TECH.O
96.81%
+3.11%
CYBR.O
96.80%
-6.98%
SAFT.O
96.78%
+6.46%
IONS Seasonality Analysis
Based on IONS's historical stock price data across all years, the probability of a positive return in December is45.45%, suggesting it maynotbe an ideal month to invest in IONS. In contrast,Juneoffers the highest probability of positive returns at72.73%, making it a potentially strong month for investment.
However, this is only a prediction based on one method, and a comprehensive assessment of the stock's future trend should consider additional factors. Our final stock price commentary incorporates three main evaluation dimensions: technical signals, Moving Average trends, and similar chart pattern matching, with the first two dimensions carrying the primary weight to ensure a more robust and accurate forecast.
Monthly Seasonality
The radar chart shows that buying Ionis Pharmaceuticals Inc (IONS.O) stock in June has the highest probability of a positive return (72.73%), while March has the lowest probability (27.27%).
Performance Seasonality
The chart shows Ionis Pharmaceuticals Inc. (IONS)'s annual stock price return for the past three years, helping you analyze price trends and identify recurring trends on an annual basis.
Should I buy Ionis Pharmaceuticals Inc (IONS.O) stock?
Based on our evaluation of the five key dimensions—Technical Signals, Moving Average trends, Short Sell Data, Similar Chart Pattern Matching and Seasonality Analysis—we have identified the following insights. IONS has several positive signals and is within a rising trend, so we believe it will perform strongly in the next couple of days or weeks. We therefore hold a positive evaluation of this stock. Our analysis conclusion for this stock is a Strong Buy candidate.
Which months have the highest win rate for buying Ionis Pharmaceuticals Inc (IONS.O) stock in a year?
The radar chart shows that buying Ionis Pharmaceuticals Inc (IONS.O) stock in June has the highest probability of a positive return (72.73%), while March has the lowest probability (27.27%).
How has Ionis Pharmaceuticals Inc. (IONS)'s stock price performed over the past three years?
IONS's stock price rose by 34.62% in 2023,decreased by -33.88% in 2024, and went up by 129.92%in 2025.
Is IONS a buy based on overall technical signals summary?
IONS has 3 buy signals and 2 sell signals now. Overall the technical rating for IONS is Neutral . Note that market conditions change all the time. In addition to technical ratings, keep an eye on the Valuation Level of IONS.
What is the trend of Ionis Pharmaceuticals Inc (IONS)'s moving average?
Ionis Pharmaceuticals Inc's overall moving average trend leans more bullish as of December 16 2025, with 0 negative signals and 4 positive signal.
What is price prediction for IONS stock next month?
The price prediction chart for Ionis Pharmaceuticals Inc (IONS.O) stock, as of December 14 2025, forecasts a -0.19% change over the next month, based on its high correlation with ALLT stock patterns. The similarity between their price movements over the analyzed periods is 97.87%. The right panel lists other stocks with similar price patterns. This prediction is updated every week.
What is price prediction 2026 for Ionis Pharmaceuticals Inc (IONS) Stock?
In Dec 2026, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $28.85. The price is predicted to fluctuate between a low of $20.89 and a high of $34.91.
What is price prediction 2030 for Ionis Pharmaceuticals Inc (IONS) Stock?
In Dec 2030, Ionis Pharmaceuticals Inc's value is forecasted to reach an average price of $31.53. The price is predicted to fluctuate between a low of $22.55 and a high of $33.07.
Positive
