Loading...

Intellectia LogoIntellectia
AI Trading Bot
Features
Markets
News
Resources
Pricing
Get Started
  1. Home
  2. Stock
  3. IONS
IONS logo

IONS Overview

-
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
OverviewStock Price PredictionTechnicalValuationFinancialsEarningsShould I BuyNews & Events
an image of Intellectia Logoan image of Intellectia

Most Trusted AI Platform for Winning Trades

TwitterYoutubeQuoraDiscordLinkedinTelegram

Copyright © 2026 Intellectia.AI. All Rights Reserved.

Company

  • Home
  • Contact
  • About Us
  • Press
  • Privacy
  • Terms of Service
  • Service Terms of Use

Resources

  • Blog
  • Tutorial
  • Help Center
  • Affiliate Program

Markets

  • Market Analysis
  • Crypto
  • Featured Screeners
  • AI Earnings Calendar
  • Market Movers
  • Stock Monitor
  • Economic Calendar
  • All US Stocks
  • All Cryptos

Tools

  • Dividend Calculator
  • Dividend Yield Calculator
  • Options Profit Calculator

Features

  • QuantAI Alpha Pick
  • SwingMax Portfolio
  • Swing Trading
  • AI Stock Picker
  • Whales Auto Tracker
  • Daytrading Center
  • Patterns Detection
  • AI Screener
  • Financial AI Agent
  • Backtesting Playground
  • AI Earnings Prediction
  • Stock Monitor
  • Technical Analysis

News

  • Overview
  • Top News
  • Daily Market Brief
  • Earnings Analysis
  • Newswire
  • Stock News
  • Crypto News
  • Institution News
  • Congress News
  • Monitor News

Compare

  • TradingView
  • SeekingAlpha
Intellectia

Loading chart...

High
73.210
Open
73.120
VWAP
72.40
Vol
2.04M
Mkt Cap
11.98B
Low
71.480
Amount
148.10M
EV/EBITDA(TTM)
--
Total Shares
165.19M
EV
11.63B
EV/OCF(TTM)
--
P/S(TTM)
12.74
Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.
Show More

Events Timeline

(ET)
2026-03-23
07:10:00
Ionis Pharmaceuticals' Zilganersen NDA Accepted for Priority Review by FDA
select
2026-02-26 (ET)
2026-02-26
09:10:00
Ionis Pharmaceuticals' Olezarsen Accepted for FDA Priority Review
select
2026-02-25 (ET)
2026-02-25
07:20:00
Ionis Reports Q4 Revenue of $203M, Beating Expectations
select

News

Newsfilter
8.5
03-30Newsfilter
FDA Approves High Dose SPINRAZA for SMA Treatment
  • FDA Approval: The U.S. FDA has approved the High Dose SPINRAZA (nusinersen), which includes 50 mg/5 mL and 28 mg/5 mL doses, aimed at providing a more effective treatment option for spinal muscular atrophy (SMA) patients, with availability expected in the coming weeks, marking a significant advancement in the treatment landscape.
  • Clinical Data Support: The high dose regimen is backed by clinical data from the DEVOTE study, which demonstrated statistically significant improvements in motor function for treatment-naïve infants, with a mean difference of 26.19 points on the CHOP-INTEND scale (+15.1 vs. -11.1, p<0.0001), offering new hope for SMA patients.
  • Optimized Treatment Protocol: The new regimen features an accelerated loading phase, allowing treatment-naïve patients to receive two 50 mg injections 14 days apart, followed by 28 mg maintenance doses every four months, designed to enhance treatment convenience and effectiveness to meet urgent patient needs.
  • Global Expansion: High Dose SPINRAZA has not only been approved in the U.S. but also in the European Union, Switzerland, and Japan, with Biogen collaborating with global regulatory authorities to advance this new treatment option to meet the diverse needs of SMA patients.
NASDAQ.COM
9.0
03-27NASDAQ.COM
GSK Seeks EMA Approval for Bepirovirsen in Chronic Hepatitis B Treatment
  • Regulatory Submission Accepted: GSK plc announced that the European Medicines Agency has accepted its marketing authorization application for bepirovirsen, an antiviral drug for adults with chronic hepatitis B, marking a significant milestone in the company's drug development efforts.
  • Clinical Trial Results: The application is based on positive outcomes from the B-Well 1 and B-Well 2 Phase III trials, indicating the drug's potential efficacy and safety in treating chronic hepatitis B, which could address a significant unmet medical need.
  • Collaborative Development: GSK licensed bepirovirsen from Ionis Pharmaceuticals and collaborated on its development, showcasing the company's strategic partnerships in advancing innovative therapeutics.
  • Market Potential Assessment: Although the drug is not yet approved anywhere globally, successful market entry could open new opportunities for GSK in the chronic hepatitis B treatment space, enhancing its competitive position in the biopharmaceutical industry.
Newsfilter
5.0
03-26Newsfilter
Ionis Pharmaceuticals Lowers Tryngolza Price to Enhance Competitive Positioning
  • Pricing Strategy: Ionis Pharmaceuticals has lowered the price of Tryngolza ahead of the sHTG decision, with analysts suggesting that this move will enhance sales potential and attract more patients, thereby increasing market share.
  • Sales Potential Increase: By reducing the price, Ionis aims to stand out in a competitive market, with analysts predicting that this action will significantly boost Tryngolza's sales over the coming quarters, further solidifying its position in the treatment landscape.
  • Competitive Positioning Optimization: This price adjustment is not only a response to market demand but may also prompt competitors to reassess their pricing strategies, potentially impacting the overall industry price structure, allowing Ionis to gain a larger market advantage.
  • Market Reaction Expectations: Analysts are generally optimistic about Tryngolza's market prospects, believing that the price reduction will enhance patient acceptance and drive sales growth, indicating Ionis's keen awareness of market dynamics.
Marketbeat
5.0
03-23Marketbeat
When Insider Selling Can Be Positive: 2 Stocks to Keep an Eye On
  • Insider Selling Trends: Insider selling is increasing, with executives from Waste Management and Ionis Pharmaceuticals selling shares, indicating a potential shift in stock performance outlooks despite strong growth prospects.

  • Stock Performance and Dividends: Waste Management's stock has risen significantly, driven by insider selling, while the company maintains a strong dividend yield, suggesting a solid investment opportunity for new investors.

  • Ionis Pharmaceuticals Outlook: Ionis Pharmaceuticals faces a cautious outlook due to declining sales of its key products, despite having a strong pipeline and potential for future growth.

  • Analyst Sentiment: Analysts are generally optimistic about both companies, with a consensus rating of "Moderate Buy" for Ionis and a positive sentiment towards Waste Management, indicating potential for continued stock price appreciation.

seekingalpha
9.0
03-23seekingalpha
Ionis Pharmaceuticals Receives FDA Priority Review for Zilganersen
  • FDA Priority Review: The US FDA has granted Priority Review to Ionis Pharmaceuticals' NDA for zilganersen, with an action date set for September 22, accelerating the drug's potential market entry for treating the rare neurological condition, Alexander disease.
  • Clinical Trial Results: In a pivotal study, children and adults receiving 50 mg of zilganersen demonstrated significant stabilization in gait speed at week 61, as measured by the 10-Meter Walk Test, indicating the drug's potential clinical value in improving patient functionality compared to the control group.
  • Disease Impact: Alexander disease affects 1 in 1 to 3 million people globally, characterized by loss of functional mobility and independence, as well as the inability to control large movements, swallowing, and airway protection, highlighting the severity of the condition and the urgent need for effective treatments.
  • Market Outlook: Ionis Pharmaceuticals outlines a peak sales target of over $2 billion for olezarsen, with optimistic projections for 2026 driven by new launches and pipeline catalysts, further bolstering investor confidence in the company's future growth prospects.
Newsfilter
9.0
03-23Newsfilter
Ionis Pharmaceuticals Receives FDA Priority Review for Zilganersen
  • FDA Priority Review: Ionis Pharmaceuticals announced that its New Drug Application for zilganersen, targeting Alexander disease, has been accepted for Priority Review by the FDA, with a PDUFA date set for September 22, 2026, indicating the drug's potential to be the first treatment for this condition and addressing a significant unmet need in the market.
  • Clinical Trial Results: In a pivotal study involving 54 participants, the 50 mg dose of zilganersen demonstrated a statistically significant 33.3% improvement in gait speed at week 61 (p=0.0412), highlighting the drug's important clinical relevance in enhancing patient mobility.
  • Market Potential: Alexander disease is a rare and often fatal neurological disorder, occurring in approximately 1 in 1 to 3 million people globally, and the successful launch of zilganersen would fill a critical gap in treatment options, thereby strengthening Ionis's market position in neurology.
  • Strategic Milestone: If approved, zilganersen will mark Ionis's first independent commercial launch in neurology, which will not only drive growth in this sector but also support the company's strategic goal of continuously developing transformative medicines for serious diseases.
Wall Street analysts forecast IONS stock price to rise
14 Analyst Rating
Wall Street analysts forecast IONS stock price to rise
13 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
65.00
Averages
92.67
High
110.00
Current: 0.000
sliders
Low
65.00
Averages
92.67
High
110.00
Barclays
NULL
to
Overweight
maintain
$95 -> $106
AI Analysis
2026-03-26
New
Reason
Barclays
Price Target
$95 -> $106
AI Analysis
2026-03-26
New
maintain
NULL
to
Overweight
Reason
Barclays raised the firm's price target on Ionis Pharmaceuticals to $106 from $95 and keeps an Overweight rating on the shares. The firm boosted its 2034 Tryngolza in severe hypertriglyceridemia estimate to $4B in the U.S. based on "supportive" physician checks. Severe hypertriglyceridemia is the most important near-term opportunity for Ionis and remains underappreciated, the analyst tells investors in a research note.
Stifel
Paul Matteis
Hold
maintain
$77 -> $83
2026-03-25
Reason
Stifel
Paul Matteis
Price Target
$77 -> $83
2026-03-25
maintain
Hold
Reason
Stifel analyst Paul Matteis raised the firm's price target on Ionis Pharmaceuticals to $83 from $77 and keeps a Hold rating on the shares after the company announced it will be lowering the annual wholesale acquisition cost of Tryngolza to $40,000 for FCS, which will be maintained for the sHTG upon approval expected in June. The $40,000 WAC is above expectations, but "probably more like ~20-25% above," the analyst tells investors.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for IONS
Unlock Now

Valuation Metrics

The current forward P/E ratio for Ionis Pharmaceuticals Inc (IONS.O) is -29.54, compared to its 5-year average forward P/E of -20.64. For a more detailed relative valuation and DCF analysis to assess Ionis Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-20.64
Current PE
-29.54
Overvalued PE
-7.42
Undervalued PE
-33.85

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-14.71
Current EV/EBITDA
-21.12
Overvalued EV/EBITDA
-10.05
Undervalued EV/EBITDA
-19.37

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
9.55
Current PS
16.79
Overvalued PS
11.81
Undervalued PS
7.29

Financials

AI Analysis
Annual
Quarterly

Related Community Screener

stock of the week - for swing trade ?
Intellectia · 496 candidates
Market Cap: >= 2.00BRegion: USRsi Category: moderateList Exchange: XNYS, XNAS, XASEMoving Average Relationship: PriceAboveMA20One Week Rise Prob: >= 60Monthly Average Dollar Volume: >= 1,000,000
Ticker
Name
Market Cap$
top bottom
AX logo
AX
Axos Financial Inc
5.69B
IONS logo
IONS
Ionis Pharmaceuticals Inc
14.01B
HXL logo
HXL
Hexcel Corp
6.48B
ITT logo
ITT
ITT Inc
17.48B
IPAR logo
IPAR
Interparfums Inc
3.28B
KO logo
KO
Coca-Cola Co
334.69B
what are the best buys for short term
Intellectia · 67 candidates
Market Cap: >= 5.00BMoving Average Relationship: PriceAboveMA20Week Price Change Pct: $3.00 - $15.00One Week Rise Prob: >= 70Monthly Average Dollar Volume: >= 2,000,000
Ticker
Name
Market Cap$
top bottom
PBR logo
PBR
Petroleo Brasileiro SA Petrobras
92.03B
ELF logo
ELF
elf Beauty Inc
5.62B
AXSM logo
AXSM
Axsome Therapeutics Inc
9.37B
DXCM logo
DXCM
Dexcom Inc
28.42B
ARM logo
ARM
Arm Holdings PLC
123.15B
MKSI logo
MKSI
MKS Inc
14.58B
give me some good optioms for tomorrow
Intellectia · 24 candidates
Market Cap: >= 5.00BRelative Vol: >= 1.50Weekly Average Turnover: >= 20,000,000Rsi 14: 45 - 55Week Price Change Pct: >= $0.00
Ticker
Name
Market Cap$
top bottom
MS logo
MS
Morgan Stanley
290.20B
GEV logo
GEV
GE Vernova Inc
181.21B
ARM logo
ARM
Arm Holdings PLC
120.87B
ENB logo
ENB
Enbridge Inc
103.23B
PBR.A logo
PBR.A
Petroleo Brasileiro SA Petrobras
81.46B
TFC logo
TFC
Truist Financial Corp
63.15B
good day trading stock for today
Intellectia · 46 candidates
Price Change Pct: >= $0.00Relative Vol: >= 1.50Weekly Average Turnover: >= 1,000,000Rsi 14: 45 - 55Moving Average Relationship: PriceCrossAboveMA5
Ticker
Name
Market Cap$
top bottom
ARM logo
ARM
Arm Holdings PLC
120.87B
TFC logo
TFC
Truist Financial Corp
63.15B
SPG logo
SPG
Simon Property Group Inc
60.42B
EOG logo
EOG
EOG Resources Inc
58.63B
EW logo
EW
Edwards Lifesciences Corp
49.41B
PEG logo
PEG
Public Service Enterprise Group Inc
39.82B
en health care quien está hoy a la alza
Intellectia · 64 candidates
Price Change Pct: >= $0.00Relative Vol: >= 1.50Weekly Average Turnover: >= 1,000,000Moving Average Relationship: PriceAboveMA5
Ticker
Name
Market Cap$
top bottom
TMO logo
TMO
Thermo Fisher Scientific Inc
239.06B
AMGN logo
AMGN
Amgen Inc
185.02B
DHR logo
DHR
Danaher Corp
170.97B
MDT logo
MDT
Medtronic PLC
128.57B
VRTX logo
VRTX
Vertex Pharmaceuticals Inc
117.00B
EW logo
EW
Edwards Lifesciences Corp
49.41B

Whales Holding IONS

S
Summit Partners Public Asset Management, LLC
Holding
IONS
+6.73%
3M Return
T
Two Sigma Investments, LP
Holding
IONS
+0.74%
3M Return
G
GW&K Investment Management, LLC
Holding
IONS
+0.10%
3M Return
T
Tweedy, Browne Company LLC
Holding
IONS
-1.28%
3M Return
D
Deerfield Management Company, L.P.
Holding
IONS
-2.62%
3M Return
P
Pinnacle Associates, Ltd.
Holding
IONS
-3.72%
3M Return

Trading Trends

    Insider
    Hedge Fund
    Congress Trading

People Also Watch

Frequently Asked Questions

What is Ionis Pharmaceuticals Inc (IONS) stock price today?

The current price of IONS is 72.52 USD — it has increased 0.51

What is Ionis Pharmaceuticals Inc (IONS)'s business?

Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.

What is the price predicton of IONS Stock?

Wall Street analysts forecast IONS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for IONS is92.67 USD with a low forecast of 65.00 USD and a high forecast of 110.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Ionis Pharmaceuticals Inc (IONS)'s revenue for the last quarter?

Ionis Pharmaceuticals Inc revenue for the last quarter amounts to 203.33M USD, decreased -10.26

What is Ionis Pharmaceuticals Inc (IONS)'s earnings per share (EPS) for the last quarter?

Ionis Pharmaceuticals Inc. EPS for the last quarter amounts to -1.41 USD, increased 113.64

How many employees does Ionis Pharmaceuticals Inc (IONS). have?

Ionis Pharmaceuticals Inc (IONS) has 1402 emplpoyees as of March 31 2026.

What is Ionis Pharmaceuticals Inc (IONS) market cap?

Today IONS has the market capitalization of 11.98B USD.