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GANX Overview

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Intellectia

Loading chart...

High
1.850
Open
1.830
VWAP
1.83
Vol
398.29K
Mkt Cap
77.20M
Low
1.810
Amount
728.21K
EV/EBITDA(TTM)
--
Total Shares
42.65M
EV
61.04M
EV/OCF(TTM)
--
P/S(TTM)
--
Gain Therapeutics, Inc. is a biotechnology company. The Company is focused on developing novel small molecule therapeutics to treat diseases across several therapeutic areas, including, central nervous system (CNS) disorders, lysosomal storage disorders (LSDs), metabolic disorders, and other diseases that can be targeted through protein degradation, such as oncology. The Company’s drug discovery platform, Magellan discovers novel allosteric binding sites on proteins implicated in a disease and to identify proprietary small molecules that bind these sites to modulate protein function and treat the underlying cause of the disease. Its lead product candidate, GT-02287, is being developed for the treatment of GBA1 Parkinson’s disease, including restoration of glucocerebrosidase or GCase, function in the lysosome, reduction of toxic lipid substrates and toxic forms of alpha-synuclein, improved survival of dopaminergic neurons, and enhance in dopamine levels.
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Events Timeline

(ET)
2026-06-29
19:00:00
Stock Futures Slightly Lower as Investors Await Middle East News
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2026-06-29
16:30:00
Gain Therapeutics Receives FDA Approval for GT-02287 IND Application
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2026-05-26 (ET)
2026-05-26
08:40:00
Gain Therapeutics Presents GT-02287 Clinical Data at International Meeting
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2026-05-11 (ET)
2026-05-11
08:00:00
Gain Therapeutics Reports Significant Progress in Q1 with GT-02287 Development
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2026-03-26 (ET)
2026-03-26
07:30:00
Gain Therapeutics Cash and Securities Rise to $20.8 Million
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2026-03-18 (ET)
2026-03-18
08:30:00
Gain Therapeutics Presents GT-02287 Clinical Data at AD/PD 2026 Conference
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2026-03-12 (ET)
2026-03-12
07:30:00
Gain Therapeutics Submits IND for GT-02287 Clinical Trial
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2026-01-06 (ET)
2026-01-06
07:30:00
Gain Therapeutics Releases Clinical Data Supporting GT-02287 Efficacy in Parkinson's Disease
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News

stocktwits
9.0
06-29stocktwits
Gain Therapeutics Receives FDA Approval for Parkinson's Clinical Trial
  • Clinical Trial Expansion: Gain Therapeutics has received FDA approval to conduct a mid-stage clinical trial of GT-02287 in the U.S., expected to start in Q3 this year, significantly enhancing its market potential in Parkinson's disease treatment.
  • Drug Candidate Progress: GT-02287 is Gain's lead drug candidate developed from the Magellan AI drug discovery platform, with early studies indicating good safety in healthy volunteers and Parkinson's patients, along with early signs of clinical benefit.
  • Clear Research Objectives: The upcoming Phase 2 trial will evaluate GT-02287 in early Parkinson's patients, particularly those with the GBA1 mutation, aiming to further assess safety while looking for signals of symptom improvement and disease progression slowing.
  • Positive Market Reaction: Following the FDA approval announcement, Gain Therapeutics' stock surged 21% in after-hours trading, with retail investor sentiment shifting from 'bearish' to 'bullish', reflecting optimism about the drug's potential.
Newsfilter
9.0
06-29Newsfilter
Gain Therapeutics Receives FDA Approval for GT-02287 Clinical Development
  • Clinical Development Milestone: Gain Therapeutics' GT-02287 has received FDA IND approval, paving the way for its Phase 2 clinical development in Parkinson's disease expected to initiate in Q3 2026, which significantly supports the company's innovative treatment efforts in neurodegenerative diseases.
  • Positive Clinical Results: GT-02287 demonstrated favorable safety and tolerability in Phase 1 trials conducted in Australia, with participants reporting improvements in smell, balance, and sleep, indicating the drug's potential to enhance patient quality of life.
  • Biomarker Analysis: In the ongoing Phase 1b extension study, participants showed an average 81% reduction in cerebrospinal fluid glucosylsphingosine (GluSph), indicating significant target engagement by GT-02287, which may provide strong support for subsequent therapeutic effects.
  • Significant Market Need: Parkinson's disease affects over 1.1 million people in the U.S., and despite existing treatments only alleviating symptoms, there are no approved therapies that halt or reverse disease progression, making the development of GT-02287 strategically vital to address this unmet medical need.
Newsfilter
8.5
06-10Newsfilter
Gain Therapeutics CEO to Participate in Neuro Perspectives Summit
  • Virtual Conference Participation: Gain Therapeutics CEO Gene Mack will participate in a virtual fireside chat at the H.C. Wainwright 7th Annual Neuro Perspectives Expert Summit on June 15, 2026, which is expected to attract attention from investors and industry experts, thereby enhancing the company's visibility in the biotechnology sector.
  • Drug Development Progress: Gain's lead drug candidate GT-02287 is currently undergoing a Phase 1b clinical trial for Parkinson's disease, demonstrating potential for treating rare genetic disorders and neurodegenerative diseases, which could open future market opportunities for the company.
  • Innovative Platform Utilization: Gain is leveraging its advanced Magellan™ platform to accelerate drug discovery, focusing on developing next-generation allosteric small molecule therapies aimed at addressing the treatment needs of difficult-to-treat diseases, thus enhancing its competitive position in the market.
  • Strengthening Investor Relations: By collaborating with H.C. Wainwright, Gain offers one-on-one meeting opportunities to enhance communication with investors, aiming to improve company transparency and attractiveness, which could further drive support from capital markets.
Yahoo Finance
8.5
05-05Yahoo Finance
Biotech Companies Targeting Parkinson's Disease
  • Gain Therapeutics Progress: Gain Therapeutics is developing the drug GT-02287 for Parkinson's, currently in Phase 1b trials, with a market cap of $88.3 million; despite an annual loss of approximately $20 million, early results indicate improvements in key biomarkers and patient motor function, potentially attracting investor interest in its future prospects.
  • Annovis Bio Challenges and Opportunities: Annovis Bio's drug buntanetap is in Phase 3 trials for Alzheimer's and Parkinson's, with a market cap of $64.2 million; despite facing a net loss of $28.9 million and financing risks, its innovation in using wearable technology to track digital biomarkers may present market opportunities.
  • Anavex Life Sciences Financial Strength: Anavex Life Sciences focuses on developing precision medicine drugs for various CNS disorders, with a market cap of $324.35 million, holding $131.7 million in cash and over three years of runway; despite regulatory challenges, its strong financial position gives it a competitive edge.
  • Market Outlook Analysis: These biotech companies' efforts in Parkinson's treatment highlight significant market potential, especially with Gain Therapeutics' drug market projected to reach $4 billion; although current valuations are below potential value, future clinical results could shift investor perceptions.
NASDAQ.COM
9.0
04-24NASDAQ.COM
Gain Therapeutics to Present Updates on Parkinson's Disease Candidate GT-02287
  • Key Presentation: Gain Therapeutics will deliver an oral presentation on May 22, 2026, at the 3rd International GBA1 Meeting in Phoenix, Arizona, highlighting updates on its Parkinson's disease candidate GT-02287, showcasing the company's ongoing innovation in neurodegenerative diseases.
  • Drug Mechanism and Effects: GT-02287 is an orally administered small molecule designed to restore the function of glucocerebrosidase (GCase) impaired in GBA1-associated and idiopathic Parkinson's disease, with preclinical studies showing improved GCase activity, reduced neuroinflammation, and protective effects on motor function.
  • Clinical Trial Progress: Early Phase 1 clinical data indicate favorable safety and CNS exposure in healthy volunteers, with significant increases in GCase activity at therapeutic doses; the drug is currently being evaluated in a Phase 1b trial allowing treatment for up to 12 months in Parkinson's disease patients.
  • Market Performance: GANX stock has traded between $1.41 and $4.34 over the past year, currently priced at $2.03, reflecting a 7.41% increase, indicating positive market sentiment towards its drug development progress.
Newsfilter
2.0
04-24Newsfilter
Gain Therapeutics Updates on GT-02287 for Parkinson's Disease
  • Clinical Trial Progress: Gain Therapeutics is currently conducting a Phase 1b clinical trial for GT-02287 across seven sites in Australia, primarily assessing its safety and tolerability in Parkinson's disease patients, which is expected to provide crucial data for the drug's market potential.
  • Innovative Drug Mechanism: As an orally administered small molecule, GT-02287 restores enzyme function impaired by GBA1 gene mutations, with preliminary data showing significant improvements in motor function and behavioral performance in animal models, indicating a potential disease-modifying effect.
  • Funding Support: The project has received funding from The Michael J. Fox Foundation and other organizations, highlighting its recognition in Parkinson's disease treatment research and potentially accelerating clinical progress.
  • International Conference Participation: The company will present an oral update on GT-02287 at the International GBA1 Meeting on May 22-23, 2026, further enhancing its visibility and influence in the biotechnology sector.
Wall Street analysts forecast GANX stock price to rise
4 Analyst Rating
Wall Street analysts forecast GANX stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
5.00
Averages
7.50
High
10.00
Current: 0.000
sliders
Low
5.00
Averages
7.50
High
10.00
Roth Capital
Boobalan Pachaiyappan
Buy
downgrade
$10 -> $8
AI Analysis
2026-05-12
Reason
Roth Capital
Boobalan Pachaiyappan
Price Target
$10 -> $8
AI Analysis
2026-05-12
downgrade
Buy
Reason
Roth Capital analyst Boobalan Pachaiyappan lowered the firm's price target on Gain Therapeutics to $8 from $10 but keeps a Buy rating on the shares. The company's GT-02287 program exploring the agent's therapeutic utility in iPD and GBA1-PD is continuing apace, with incremental data update expected in the upcoming GBA1 conference in Arizona this month, the analyst tells investors in a research note. Roth adds that upon FDA clearance, Gain is slated to begin a Phase 2 study in Q3 which could also involve a $60M equity financing.
Roth Capital
NULL -> Buy
upgrade
$6 -> $10
2025-12-19
Reason
Roth Capital
Price Target
$6 -> $10
2025-12-19
upgrade
NULL -> Buy
Reason
Roth Capital raised the firm's price target on Gain Therapeutics to $10 from $6 and keeps a Buy rating on the shares. The firm says GT-02287 demonstrated blood-brain barrier penetration and triggered a reduction in GluSph levels in the Phase 1b study. This offers "direct mechanistic evidence" for GCase target engagement, the analyst tells investors in a research note. Roth cites the data for the target increase.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for GANX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Gain Therapeutics Inc (GANX.O) is 0.00, compared to its 5-year average forward P/E of -2.90. For a more detailed relative valuation and DCF analysis to assess Gain Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.90
Current PE
0.00
Overvalued PE
-1.98
Undervalued PE
-3.82

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
646.84
Current PS
0.00
Overvalued PS
1699.99
Undervalued PS
-406.31

Financials

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Frequently Asked Questions

What is Gain Therapeutics Inc (GANX) stock price today?

The current price of GANX is 1.825 USD — it has increased 0.83

What is Gain Therapeutics Inc (GANX)'s business?

Gain Therapeutics, Inc. is a biotechnology company. The Company is focused on developing novel small molecule therapeutics to treat diseases across several therapeutic areas, including, central nervous system (CNS) disorders, lysosomal storage disorders (LSDs), metabolic disorders, and other diseases that can be targeted through protein degradation, such as oncology. The Company’s drug discovery platform, Magellan discovers novel allosteric binding sites on proteins implicated in a disease and to identify proprietary small molecules that bind these sites to modulate protein function and treat the underlying cause of the disease. Its lead product candidate, GT-02287, is being developed for the treatment of GBA1 Parkinson’s disease, including restoration of glucocerebrosidase or GCase, function in the lysosome, reduction of toxic lipid substrates and toxic forms of alpha-synuclein, improved survival of dopaminergic neurons, and enhance in dopamine levels.

What is the price predicton of GANX Stock?

Wall Street analysts forecast GANX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for GANX is7.50 USD with a low forecast of 5.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Gain Therapeutics Inc (GANX)'s revenue for the last quarter?

Gain Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Gain Therapeutics Inc (GANX)'s earnings per share (EPS) for the last quarter?

Gain Therapeutics Inc. EPS for the last quarter amounts to -0.13 USD, decreased -18.75

How many employees does Gain Therapeutics Inc (GANX). have?

Gain Therapeutics Inc (GANX) has 20 emplpoyees as of July 08 2026.

What is Gain Therapeutics Inc (GANX) market cap?

Today GANX has the market capitalization of 77.20M USD.