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FGEN Overview

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Intellectia

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High
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Open
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VWAP
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Vol
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Mkt Cap
102.46M
Low
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Amount
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EV/EBITDA(TTM)
--
Total Shares
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EV
-24.71M
EV/OCF(TTM)
--
P/S(TTM)
4.73
Kyntra Bio, Inc., formerly FibroGen, Inc., is a biopharmaceutical company. The Company is focused on development of novel therapies in oncology and rare disease. The Company continues to evaluate the development plan for the Phase III trial of roxadustat in anemia associated with lower-risk myelodysplastic syndrome (LR-MDS) in the U.S. FG-3246 (also known as FOR46), a first-in-class antibody-drug conjugate (ADC) targeting CD46, is in Phase II development for the treatment of metastatic castration-resistant prostate cancer. This program also includes the development of FG-3180, an associated CD46-targeted PET biomarker. Roxadustat (EVRENZO) is approved in Europe, Japan, and numerous other countries for the treatment of anemia in chronic kidney disease (CKD) patients on dialysis and not on dialysis.
Show More

Events Timeline

(ET)
2026-02-23
17:20:00
Kyntra Bio to Present FG-3246 Data at ASCO GU Conference
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2026-01-07 (ET)
2026-01-07
07:40:00
FibroGen Rebrands to Kyntra Bio, Trading Under New Symbol KYNB
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2025-12-15 (ET)
2025-12-15
07:10:00
FibroGen Receives FDA Orphan Drug Designation for Roxadustat
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2025-11-10 (ET)
2025-11-10
16:14:27
FibroGen Announces Q3 Earnings Per Share of $3.25, Below Consensus Estimate of $4.01
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2025-09-24 (ET)
2025-09-24
07:03:24
FibroGen Launches Phase 2 Study of FG-3246
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2025-09-10 (ET)
2025-09-10
15:49:42
SEC Accuses Former FibroGen CMO of Misleading Statements Regarding Clinical Trial Outcomes
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2025-09-02 (ET)
2025-09-02
07:09:13
FibroGen finalizes $220M sale of FibroGen China to AstraZeneca
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2025-08-18 (ET)
2025-08-18
07:05:35
FibroGen receives approval for AstraZeneca's acquisition of its China operations.
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News

Globenewswire
2.0
02-23Globenewswire
FG-3246 and Enzalutamide Combination Therapy Shows Promising Results
  • Significant Efficacy: The combination of FG-3246 and enzalutamide demonstrated a median radiographic progression-free survival (rPFS) of 7.0 months in biomarker-unselected metastatic castration-resistant prostate cancer (mCRPC) patients, with a notable 10.1 months in those who had only one prior ARPI, highlighting FG-3246's potential in earlier treatment lines.
  • Biomarker Potential: Higher tumor uptake of FG-3180 showed a trend towards a higher probability of PSA50 response (p=0.053), indicating FG-3180's potential as a significant biomarker for patient selection, thereby enhancing the clinical applicability of FG-3246.
  • Safety Validation: The safety profile of the combination therapy was similar to that observed in the previous Phase 1 trial of FG-3246, with the risk of neutropenia effectively mitigated through G-CSF prophylaxis, suggesting the clinical feasibility of this combination treatment.
  • Trial Progress: The Phase 2 monotherapy trial of FG-3246 is on track for interim analysis in the second half of 2026, which will further validate its efficacy and safety in treating metastatic castration-resistant prostate cancer.
Newsfilter
9.0
02-23Newsfilter
FG-3246 and Enzalutamide Combination Therapy Shows Promising Results
  • Clinical Trial Results: The combination therapy of FG-3246 and enzalutamide demonstrated a median radiographic progression-free survival (rPFS) of 7.0 months in biomarker-unselected metastatic castration-resistant prostate cancer patients, with a notable 10.1 months rPFS in patients who progressed after only one prior ARPI, indicating its potential in earlier lines of therapy.
  • Biomarker Potential: Higher tumor uptake of FG-3180 showed a trend towards a higher probability of PSA50 response (p=0.053), highlighting FG-3180's potential as a patient selection biomarker, which may play a crucial role in future clinical trials.
  • Safety Analysis: The safety profile of the combination therapy was similar to that observed in the previous FG-3246 monotherapy trial, with the risk of neutropenia effectively mitigated through G-CSF prophylaxis, while common treatment-related adverse events included fatigue, peripheral neuropathy, and anorexia.
  • Future Outlook: The Phase 2 monotherapy trial of FG-3246 is on track for interim analysis in the second half of 2026, further validating its application potential in metastatic castration-resistant prostate cancer and exploring the efficacy of FG-3180 as a biomarker.
Globenewswire
9.0
2025-12-15Globenewswire
FibroGen Receives FDA Orphan Drug Designation for Roxadustat in MDS Treatment
  • Orphan Drug Designation: FibroGen's roxadustat has received FDA Orphan Drug Designation for treating approximately 58,000 MDS patients in the U.S., underscoring the urgent treatment gap and potentially providing the company with a competitive market advantage.
  • Clinical Trial Progress: The company plans to submit the Phase 3 protocol for roxadustat in Q4 2025, aiming to improve treatment outcomes for patients with high transfusion burden, which is expected to significantly enhance patient quality of life.
  • Market Potential: With about 50% of MDS patients reliant on transfusions and existing treatments achieving less than 50% efficacy, the oral administration of roxadustat is poised to meet the demand for convenient therapies, filling a critical market void.
  • Strategic Collaboration: FibroGen is collaborating with Astellas to commercialize roxadustat across multiple markets including Japan and Europe, further strengthening its competitive position and influence in the global market.
Newsfilter
9.0
2025-12-15Newsfilter
FibroGen Receives FDA Orphan Drug Designation for Roxadustat, Plans Phase 3 Submission in Q4 2025
  • Orphan Drug Designation: FibroGen's roxadustat has received Orphan Drug Designation from the FDA for treating approximately 58,000 patients with lower-risk myelodysplastic syndromes (LR-MDS) in the U.S., highlighting a significant treatment gap and potentially enhancing the company's competitive position in this market.
  • Clinical Trial Progress: The company plans to submit the Phase 3 protocol for roxadustat in Q4 2025, aiming to improve transfusion independence in patients with high transfusion burden, thereby solidifying its leadership in the MDS treatment space.
  • Market Demand: Currently, about 50% of MDS patients require regular blood transfusions, with existing first-line treatments achieving less than 50% transfusion independence; roxadustat's clinical data indicates its potential to meet the urgent market need for new therapies.
  • Strategic Collaboration: FibroGen is collaborating with Astellas to commercialize roxadustat across multiple markets, including Japan and Europe, which is expected to expand market share and enhance the product's global impact.
NASDAQ.COM
9.0
2025-12-15NASDAQ.COM
FibroGen: Roxadustat Receives Orphan Drug Designation from FDA for MDS
  • FDA Orphan Drug Designation: FibroGen, Inc. announced that the FDA has granted roxadustat Orphan Drug Designation for treating myelodysplastic syndromes, following positive results in a post-hoc analysis from the Phase 3 MATTHERHORN trial.

  • Future Submissions: The company is preparing to finalize the Phase 3 protocol for submission to the FDA, expected in the fourth quarter of 2025.

  • Current Approvals: Roxadustat is already approved in Europe, Japan, and other countries for treating anemia of chronic kidney disease (CKD) in both dialysis and non-dialysis adult patients.

  • Disclaimer: The views expressed in the article are those of the author and do not necessarily reflect the opinions of Nasdaq, Inc.

Globenewswire
1.0
2025-12-02Globenewswire
FibroGen to Present at Oppenheimer Rare Disease Summit with Key Catalysts
  • Key Conference Participation: FibroGen will attend the Oppenheimer Rare Disease Summit on December 11, 2025, in New York, where CEO Thane Wettig will participate in a panel discussing potential stock-moving catalysts in rare diseases, highlighting the company's strategic focus.
  • One-on-One Investor Meetings: The management team will be available for one-on-one meetings during the conference, aiming to attract investor interest in their novel therapies, particularly Roxadustat for chronic kidney disease patients and FG-3246 for prostate cancer treatment.
  • New Therapy Development: FibroGen is evaluating the Phase 3 trial plan for Roxadustat in the U.S. targeting lower-risk myelodysplastic syndrome (LR-MDS), which, if successful, could present significant market opportunities for the company.
  • Frontier Biopharmaceuticals: As a biopharmaceutical company focused on developing novel therapies in cancer biology and anemia, FibroGen's innovative drugs like FG-3246 and FG-3180 have the potential to transform treatment paradigms, enhancing the company's competitiveness in the biopharmaceutical sector.
Wall Street analysts forecast FGEN stock price to rise
2 Analyst Rating
Wall Street analysts forecast FGEN stock price to rise
1 Buy
1 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
43.00
Averages
43.00
High
43.00
Current: 0.000
sliders
Low
43.00
Averages
43.00
High
43.00
H.C. Wainwright
H.C. Wainwright
NULL -> Buy
upgrade
$10 -> $43
AI Analysis
2025-08-07
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$10 -> $43
AI Analysis
2025-08-07
upgrade
NULL -> Buy
Reason
H.C. Wainwright adjusted the firm's price target on FibroGen to $43 from $10 and keeps a Buy rating on the shares following the recent reverse stock split. The firm also cites an increased discount rate pending visibility from both the FG-3246 and roxadustat programs after Fibrogen disclosed "positive details" from a Type C meeting with the FDA. The firm, which calls the update an "important step forward for Fibrogen and roxa," awaits additional updates, including trial start dates and possible inclusion of a development/commercial partner.
HC Wainwright & Co.
Joseph Pantginis
Strong Buy
Reiterates
$10
2025-03-18
Reason
HC Wainwright & Co.
Joseph Pantginis
Price Target
$10
2025-03-18
Reiterates
Strong Buy
Reason

Valuation Metrics

The current forward P/E ratio for FibroGen Inc (FGEN.O) is -0.54, compared to its 5-year average forward P/E of -4.02. For a more detailed relative valuation and DCF analysis to assess FibroGen Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.02
Current PE
-0.54
Overvalued PE
0.49
Undervalued PE
-8.54

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.18
Current EV/EBITDA
0.58
Overvalued EV/EBITDA
-0.31
Undervalued EV/EBITDA
-6.04

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.02
Current PS
5.92
Overvalued PS
9.25
Undervalued PS
0.80

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Frequently Asked Questions

What is FibroGen Inc (FGEN) stock price today?

The current price of FGEN is 0 USD — it has increased 0

What is FibroGen Inc (FGEN)'s business?

Kyntra Bio, Inc., formerly FibroGen, Inc., is a biopharmaceutical company. The Company is focused on development of novel therapies in oncology and rare disease. The Company continues to evaluate the development plan for the Phase III trial of roxadustat in anemia associated with lower-risk myelodysplastic syndrome (LR-MDS) in the U.S. FG-3246 (also known as FOR46), a first-in-class antibody-drug conjugate (ADC) targeting CD46, is in Phase II development for the treatment of metastatic castration-resistant prostate cancer. This program also includes the development of FG-3180, an associated CD46-targeted PET biomarker. Roxadustat (EVRENZO) is approved in Europe, Japan, and numerous other countries for the treatment of anemia in chronic kidney disease (CKD) patients on dialysis and not on dialysis.

What is the price predicton of FGEN Stock?

Wall Street analysts forecast FGEN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for FGEN is43.00 USD with a low forecast of 43.00 USD and a high forecast of 43.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is FibroGen Inc (FGEN)'s revenue for the last quarter?

FibroGen Inc revenue for the last quarter amounts to 1.08M USD, increased 774.80

What is FibroGen Inc (FGEN)'s earnings per share (EPS) for the last quarter?

FibroGen Inc. EPS for the last quarter amounts to 49.61 USD, decreased -1267.29

How many employees does FibroGen Inc (FGEN). have?

FibroGen Inc (FGEN) has 225 emplpoyees as of March 12 2026.

What is FibroGen Inc (FGEN) market cap?

Today FGEN has the market capitalization of 102.46M USD.