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DTIL Overview

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ET
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Intellectia

Loading chart...

High
5.460
Open
4.720
VWAP
5.14
Vol
480.14K
Mkt Cap
128.78M
Low
4.610
Amount
2.47M
EV/EBITDA(TTM)
--
Total Shares
24.07M
EV
100.01M
EV/OCF(TTM)
--
P/S(TTM)
76.96
Precision BioSciences, Inc. is a clinical-stage gene editing company dedicated to improving life (DTIL) with its proprietary ARCUS genome editing platform. Using ARCUS, the Company’s pipeline is comprised of in vivo gene editing candidates designed to deliver cures for a range of genetic and infectious diseases. The ARCUS platform is used to develop in vivo gene editing therapies for gene edits, including gene insertion, elimination, and excision. The Company's in vivo gene editing pipeline programs include PBGENE-HBV, PBGENE-3243, PBGENE-DMD, PBGENE-LIVER, PBGENE-CNS, PBGENE-NVS and iECURE-OTC. PBGENE-HBV is its lead in vivo gene editing program designed to eliminate cccDNA, the key source of replicating hepatitis B virus (HBV) and inactivating integrated HBV DNA in hepatocytes. Its PBGENE-3243 program is a first of its kind potential treatment for m.3243 associated mitochondrial disease. The Company's iECURE-OTC program is developed in partnership with iECURE, Inc.
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Events Timeline

(ET)
2026-03-10
07:30:00
Precision BioSciences Presents PBGENE-DMD Study Data
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2026-03-09 (ET)
2026-03-09
07:20:00
Precision BioSciences' PBGENE-DMD Receives FDA Fast Track Designation
select
2026-03-02 (ET)
2026-03-02
07:31:00
Precision BioSciences Receives $7.5M Milestone Payment
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2026-02-11 (ET)
2026-02-11
07:40:00
Precision BioSciences Receives FDA Study May Proceed Notification
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2025-11-10 (ET)
2025-11-10
18:20:24
Precision BioSciences Launches $75 Million Common Stock and Warrant Offering
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2025-11-03 (ET)
2025-11-03
07:08:11
Precision BioSciences Announces Q3 Earnings Per Share of $1.84, Below Consensus Estimate of $2.21
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2025-10-09 (ET)
2025-10-09
07:19:58
Precision BioSciences Releases Data on ARCUS Nucleases
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2025-10-07 (ET)
2025-10-07
07:06:50
Precision BioSciences Launches Initial U.S. Clinical Trial Site for PBGENE-HBV
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News

Yahoo Finance
8.5
03-10Yahoo Finance
PinnedPBGENE-DMD Treatment Shows Durable Efficacy
  • Preclinical Study Findings: PBGENE-DMD demonstrates significant muscle pathology improvements in a humanized DMD mouse model, with reductions of approximately 50-65% in CK levels at 90 days post-treatment, indicating substantial muscle integrity improvements and potential long-term treatment hope for DMD patients.
  • Functional Improvements: Treated mice maintain approximately 81%-84% of maximal force output and 89%-92% of tetanic force output over nine months, showcasing the durability and efficacy of the treatment, supporting its potential as a one-time therapy aimed at long-term muscle function enhancement.
  • Satellite Cell Editing: PBGENE-DMD promotes the restoration of functional muscle proteins across key muscle groups, including cardiac and skeletal muscles, through the editing of muscle satellite stem cells, with levels of functional dystrophin protein increasing over time, potentially providing sustained functional improvements for DMD patients.
  • Clinical Trial Preparations: Precision BioSciences is preparing to initiate the Phase 1/2 FUNCTION-DMD clinical trial, expected to enroll DMD patients aged 2-7, aiming to evaluate the safety, tolerability, and efficacy of PBGENE-DMD, further validating its clinical application potential.
NASDAQ.COM
9.0
03-09NASDAQ.COM
Precision BioSciences' PBGENE-DMD Receives FDA Fast Track Designation
  • Fast Track Designation: Precision BioSciences' investigational therapy PBGENE-DMD has received Fast Track designation from the FDA, aimed at accelerating the development of treatments for Duchenne muscular dystrophy, addressing significant unmet medical needs in this area.
  • Regulatory Milestone: CEO Michael Amoroso stated that this designation represents an important regulatory milestone for PBGENE-DMD, highlighting the urgent need for effective treatments for patients suffering from Duchenne muscular dystrophy.
  • Clinical Advancement: The Fast Track designation, along with the recent IND clearance, is expected to propel PBGENE-DMD's clinical investigation in boys with Duchenne muscular dystrophy, enhancing its competitive position in the market.
  • Market Potential: With FDA support, PBGENE-DMD is poised to achieve positive outcomes in future clinical trials, providing a strong impetus for Precision BioSciences' growth in the rare disease sector.
Newsfilter
9.0
03-09Newsfilter
Precision BioSciences Receives FDA Fast Track Designation for PBGENE-DMD
  • Fast Track Designation: Precision BioSciences' PBGENE-DMD has received FDA Fast Track designation, aimed at expediting the development and review of treatments for Duchenne muscular dystrophy (DMD), highlighting the significant unmet medical need in this area.
  • Clinical Study Plans: The company plans to host a virtual KOL event on March 17, 2026, to discuss PBGENE-DMD and its upcoming Phase 1/2 FUNCTION-DMD clinical study, which is expected to provide new treatment options for DMD patients.
  • Technological Innovation: PBGENE-DMD utilizes a gene excision approach targeting mutations in exons 45-55, potentially offering durable functional muscle improvement for up to 60% of boys with DMD, showcasing its uniqueness and potential in the treatment landscape.
  • Preclinical Research Results: In preclinical studies, PBGENE-DMD demonstrated significant functional improvements in a DMD mouse model, restoring function across cardiac, diaphragm, and various skeletal muscles, indicating its feasibility and efficacy for future clinical applications.
Yahoo Finance
9.0
03-09Yahoo Finance
FDA Grants Fast Track Designation to PBGENE-DMD for DMD Treatment
  • Fast Track Designation: Precision BioSciences announced that its gene editing therapy PBGENE-DMD has received Fast Track designation from the FDA, aimed at expediting the development of treatments for Duchenne muscular dystrophy (DMD), highlighting the significant unmet medical need in this condition.
  • Clinical Study Plans: The company plans to host a virtual webinar on March 17, 2026, to discuss the clinical utility of PBGENE-DMD and the upcoming Phase 1/2 FUNCTION-DMD clinical study, which is expected to provide new treatment options for DMD patients.
  • Therapeutic Innovation: PBGENE-DMD utilizes a unique gene excision approach targeting mutations in exons 45-55 affecting 60% of DMD patients, designed to permanently edit the dystrophin gene through a single AAV vector encoding two ARCUS proteins, thereby restoring the production of functional muscle protein.
  • Preclinical Study Results: In preclinical studies, PBGENE-DMD demonstrated significant functional improvements by restoring near full-length functional dystrophin protein across various muscle types, indicating its potential efficacy and long-term durability in treating DMD.
Newsfilter
9.0
02-11Newsfilter
FDA Approval Enables Initiation of DMD Clinical Trial
  • Clinical Trial Launch: The FDA's 'Study May Proceed' notification allows Precision BioSciences to initiate the FUNCTION-DMD Phase 1/2 clinical trial, aimed at evaluating the safety and efficacy of PBGENE-DMD in patients with Duchenne muscular dystrophy (DMD), marking a significant advancement in the gene editing field.
  • Gene Editing Innovation: PBGENE-DMD employs a gene excision approach designed to permanently correct the dystrophin gene in approximately 60% of DMD patients, restoring near full-length functional dystrophin protein, which is expected to significantly improve functional outcomes for patients and offer potential long-term therapeutic effects.
  • Investor Event Arrangement: The company plans to host a virtual investor event in March following the Muscular Dystrophy Association meeting to discuss the PBGENE-DMD program and the FUNCTION-DMD clinical study, featuring participation from multiple key opinion leaders, thereby enhancing collaboration with patients and the medical community.
  • Future Outlook: The first clinical trial site is expected to be activated in the first half of 2026, with initial data anticipated by the end of 2026; if supportive data is obtained, the company will engage with the FDA to align on the regulatory path forward, advancing treatment options for DMD.
Yahoo Finance
9.0
02-11Yahoo Finance
Precision BioSciences Receives FDA Approval for Clinical Trial
  • FDA Clinical Trial Approval: Precision BioSciences received a 'Study May Proceed' notification from the FDA, allowing the initiation of the FUNCTION-DMD Phase 1/2 clinical trial to evaluate the safety and efficacy of PBGENE-DMD in patients with Duchenne muscular dystrophy, marking a significant advancement in the gene editing field.
  • Gene Editing Innovation: PBGENE-DMD utilizes a gene excision approach targeting mutations in exons 45-55 affecting 60% of DMD patients, aiming to restore near full-length functional dystrophin protein, which is expected to significantly improve muscle function and address existing treatment gaps.
  • Clinical Trial Progress: The company plans to activate its first clinical trial site in the U.S. in the first half of 2026, with initial data expected by year-end 2026; if results are supportive, the company will engage with the FDA to discuss the regulatory pathway forward, demonstrating its commitment to accelerating treatment progress.
  • Investor Event Arrangement: Precision plans to host a virtual investor event in March following the Muscular Dystrophy Association meeting to discuss the PBGENE-DMD program and the FUNCTION-DMD clinical study, featuring participation from key opinion leaders in the medical and patient advocacy communities, enhancing communication with stakeholders.
Wall Street analysts forecast DTIL stock price to rise
2 Analyst Rating
Wall Street analysts forecast DTIL stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
30.00
Averages
45.00
High
60.00
Current: 0.000
sliders
Low
30.00
Averages
45.00
High
60.00
HC Wainwright & Co.
Patrick Trucchio
Strong Buy
Reiterates
$60
AI Analysis
2025-03-28
Reason
HC Wainwright & Co.
Patrick Trucchio
Price Target
$60
AI Analysis
2025-03-28
Reiterates
Strong Buy
Reason
HC Wainwright & Co.
Patrick Trucchio
Strong Buy
Reiterates
$60
2025-03-19
Reason
HC Wainwright & Co.
Patrick Trucchio
Price Target
$60
2025-03-19
Reiterates
Strong Buy
Reason

Valuation Metrics

The current forward P/E ratio for Precision BioSciences Inc (DTIL.O) is -1.32, compared to its 5-year average forward P/E of -1.88. For a more detailed relative valuation and DCF analysis to assess Precision BioSciences Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.88
Current PE
-1.32
Overvalued PE
0.70
Undervalued PE
-4.46

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.11
Current EV/EBITDA
-1.36
Overvalued EV/EBITDA
2.85
Undervalued EV/EBITDA
-3.07

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
6.47
Current PS
6.36
Overvalued PS
13.80
Undervalued PS
-0.87

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Frequently Asked Questions

What is Precision BioSciences Inc (DTIL) stock price today?

The current price of DTIL is 5.35 USD — it has increased 13.59

What is Precision BioSciences Inc (DTIL)'s business?

Precision BioSciences, Inc. is a clinical-stage gene editing company dedicated to improving life (DTIL) with its proprietary ARCUS genome editing platform. Using ARCUS, the Company’s pipeline is comprised of in vivo gene editing candidates designed to deliver cures for a range of genetic and infectious diseases. The ARCUS platform is used to develop in vivo gene editing therapies for gene edits, including gene insertion, elimination, and excision. The Company's in vivo gene editing pipeline programs include PBGENE-HBV, PBGENE-3243, PBGENE-DMD, PBGENE-LIVER, PBGENE-CNS, PBGENE-NVS and iECURE-OTC. PBGENE-HBV is its lead in vivo gene editing program designed to eliminate cccDNA, the key source of replicating hepatitis B virus (HBV) and inactivating integrated HBV DNA in hepatocytes. Its PBGENE-3243 program is a first of its kind potential treatment for m.3243 associated mitochondrial disease. The Company's iECURE-OTC program is developed in partnership with iECURE, Inc.

What is the price predicton of DTIL Stock?

Wall Street analysts forecast DTIL stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for DTIL is45.00 USD with a low forecast of 30.00 USD and a high forecast of 60.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Precision BioSciences Inc (DTIL)'s revenue for the last quarter?

Precision BioSciences Inc revenue for the last quarter amounts to 13.00K USD, decreased -97.74

What is Precision BioSciences Inc (DTIL)'s earnings per share (EPS) for the last quarter?

Precision BioSciences Inc. EPS for the last quarter amounts to -1.84 USD, decreased -18.22

How many employees does Precision BioSciences Inc (DTIL). have?

Precision BioSciences Inc (DTIL) has 108 emplpoyees as of March 11 2026.

What is Precision BioSciences Inc (DTIL) market cap?

Today DTIL has the market capitalization of 128.78M USD.