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CRDF Overview

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ET
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ET
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Intellectia

Loading chart...

High
1.815
Open
1.770
VWAP
1.78
Vol
713.70K
Mkt Cap
121.69M
Low
1.730
Amount
1.27M
EV/EBITDA(TTM)
--
Total Shares
68.36M
EV
64.75M
EV/OCF(TTM)
--
P/S(TTM)
202.89
Cardiff Oncology, Inc. is a clinical-stage biotechnology company. It is leveraging PLK1 inhibition, a well-validated oncology drug target, to develop novel therapies across a range of cancers with unmet medical need. It is focused on clinical programs in indications, such as RAS-mutated metastatic colorectal cancer (mCRC), and in investigator-initiated trials in metastatic pancreatic ductal adenocarcinoma (mPDAC), small cell lung cancer (SCLC), and triple negative breast cancer (TNBC). Its lead drug candidate, Onvansertib, is an oral, small-molecule drug candidate that is highly specific for PLK1 inhibition with a 24-hour half-life. It has other ongoing and planned clinical trials of onvansertib: one trial (CRDF-004) in first-line treatment in patients with RAS-mutated mCRC, and investigator-initiated trials in first-line mPDAC, relapsed SCLC and unresectable locally advanced or metastatic TNBC.
Show More

Events Timeline

(ET)
2026-04-09
16:10:00
Cardiff Oncology Appoints Mani Mohindru as CEO
select
2026-01-27 (ET)
2026-01-27
07:20:00
Cardiff Oncology Appoints New CEO
select
2026-01-27
07:10:00
Cardiff Oncology Announces Positive Update on CRDF-004 Clinical Trial
select
2025-11-06 (ET)
2025-11-06
18:02:27
Cardiff Oncology increases FY25 revenue forecast to $76M-$78M, up from $72M-$76M
select
2025-11-06
17:59:01
Cardiff Oncology Announces Q3 Earnings Per Share of 17 Cents, Below Consensus Estimate of 21 Cents
select

News

seekingalpha
5.0
04-09seekingalpha
Cardiff Oncology Appoints New CEO and Executives
  • Executive Appointments: Cardiff Oncology has appointed Mani Mohindru as President and CEO, who previously served as interim CEO and will remain on the Board, a move aimed at ensuring leadership stability and continuity within the company.
  • Financial and Operational Leadership: Josh Muntner has been appointed CFO and Ajay Aggarwal as COO, effective April 6 and April 27 respectively, with Muntner having prior experience as CFO at Imvax and Mesoblast, while Aggarwal brings expertise from his role as Senior VP at Aclaris Therapeutics, enhancing the company's leadership depth.
  • Strategic Execution Capability: The addition of these executives is expected to bolster Cardiff Oncology's capabilities in clinical development and financial management, particularly in advancing its treatment strategies for RAS-mutated metastatic colorectal cancer, potentially accelerating clinical strategy implementation.
  • Market Reaction: Despite the leadership changes, the market remains cautious about Onvansertib's potential in first-line colorectal cancer treatment, reflecting investor concerns and expectations regarding the company's future trajectory.
moomoo
5.0
04-09moomoo
CARDIFF ONCOLOGY INC NAMES JOSH MUNTNER CFO STARTING APRIL 6 AND AJAY AGGARWAL COO BEGINNING APRIL 27
  • New Appointments: Josh Munter and Jay Aggarwal have been appointed as Chief Financial Officers (CFOs) at Cardiff Oncology.
  • Effective Dates: Josh Munter's appointment is effective from April 6, while Jay Aggarwal's is effective from April 27.
moomoo
5.0
04-09moomoo
CARDIFF ONCOLOGY INC NAMES MANI MOHINDRU PRESIDENT AND CEO; HE WILL REMAIN ON THE BOARD
  • Leadership Announcement: Manihindru has been appointed as the President and CEO of Cardiff Oncology.

  • Board Membership: He will continue to serve as a member of the board.

NASDAQ.COM
9.5
02-25NASDAQ.COM
Cardiff Oncology Reports 2025 Financial Results and Business Update
  • Financial Overview: Cardiff Oncology reported royalty revenues of $0.6 million for 2025, a slight decrease from $0.7 million in 2024, while total operating expenses remained stable at $49.6 million, resulting in a net loss of $45.9 million or $0.69 per share, which is an improvement over the previous year's loss of $45.5 million or $0.95 per share, indicating better financial management.
  • Clinical Trial Progress: The Phase 2 CRDF-004 trial for RAS-mutated metastatic colorectal cancer showed that the 30 mg Onvansertib combined with FOLFIRI/bev achieved a 72.2% objective response rate, significantly higher than the 43.2% in standard care arms, laying a solid foundation for advancing into a registrational program, with detailed data and regulatory plans expected in the first half of 2026.
  • Cash Position: As of 2025, Cardiff's cash, cash equivalents, and short-term investments totaled $58.3 million, which is expected to fund operations into the first quarter of 2027, demonstrating strong financial management and providing a buffer for ongoing research and development.
  • Leadership Changes: In January 2026, Cardiff announced executive changes with Mani Mohindru appointed as interim CEO and Brigitte Lindsay promoted to Chief Accounting Officer, reflecting the company's strategic restructuring to support late-stage development while actively searching for a permanent CEO and CFO to enhance management stability.
seekingalpha
9.5
02-24seekingalpha
Cardiff Oncology Reports FY EPS Beat Amid Revenue Decline
  • Earnings Highlights: Cardiff Oncology reported a FY GAAP EPS of -$0.69, beating expectations by $0.08, indicating some financial resilience despite still being in negative territory.
  • Revenue Trends: The company generated $0.59M in revenue, a 13.2% year-over-year decline, yet it surpassed market expectations by $0.14M, suggesting a stable customer base amid challenges.
  • Leadership Changes: Following the earnings release, Cardiff Oncology experienced a leadership shakeup, which could impact the company's strategic direction and investor confidence, necessitating close monitoring of management stability.
  • Future Outlook: Despite current challenges, the market remains cautiously optimistic about Cardiff Oncology's future performance, particularly with the upcoming Phase II data update for Onvansertib in RAS-mutated mCRC, which may present new growth opportunities.
Benzinga
5.0
01-28Benzinga
Cardiff Oncology Management Shakeup and Trial Update
  • Management Changes: Cardiff Oncology announced the resignation of CEO Mark Erlander and CFO James Levine, with board member Mani Mohindru appointed as interim CEO, reflecting a focus on execution and clinical advancement that may impact investor confidence negatively.
  • Clinical Trial Data Update: In the CRDF-004 Phase 2 trial for RAS-mutated metastatic colorectal cancer, the 30 mg dose group achieved a confirmed objective response rate of 72.2%, significantly higher than the 43.2% in the standard care group, indicating the potential efficacy of the new drug and possibly driving future registrational trials.
  • Registrational Trial Plans: Based on clinical data, Cardiff Oncology plans to initiate a registrational trial later this year comparing onvansertib with standard care for 1L patients, which, if successful, could help expand market share.
  • Analyst Perspective: William Blair lowered the probability of success from 50% to 45%, suggesting that the abrupt management changes and narrow focus on onvansertib may limit market opportunities, leading to a 31.9% drop in stock price to $2, close to the 52-week low.
Wall Street analysts forecast CRDF stock price to rise
6 Analyst Rating
Wall Street analysts forecast CRDF stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
10.00
Averages
13.67
High
19.00
Current: 0.000
sliders
Low
10.00
Averages
13.67
High
19.00
Piper Sandler
Overweight
to
NULL
downgrade
$10 -> $6
AI Analysis
2026-02-25
Reason
Piper Sandler
Price Target
$10 -> $6
AI Analysis
2026-02-25
downgrade
Overweight
to
NULL
Reason
Piper Sandler lowered the firm's price target on Cardiff Oncology to $6 from $10 and keeps an Overweight rating on the shares. The firm notes Cardiff ended 2025 with cash of $58.3M to fund operations into Q1 2027. Piper is pushing out onvansertib approval to 2030, removing value for other cancers and rolling forward its discount period to mid-2027.
H.C. Wainwright
H.C. Wainwright
Buy
maintain
$10
2026-01-28
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$10
2026-01-28
maintain
Buy
Reason
H.C. Wainwright says the selloff yesterday in shares of Cardiff Oncology brings an attractive entry point. The firm finds updated CRDF-004 trial results "highly encouraging." It expects a more mature clinical dataset from the CRDF-004 study in the first half of 2026. The market "overreaction provides an attractive entry point," says H.C. Wainwright. The analyst keeps a Buy rating on Cardiff Oncology with a $10 price target.
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Valuation Metrics

The current forward P/E ratio for Cardiff Oncology Inc (CRDF.O) is 0.00, compared to its 5-year average forward P/E of -3.54. For a more detailed relative valuation and DCF analysis to assess Cardiff Oncology Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.54
Current PE
0.00
Overvalued PE
-0.74
Undervalued PE
-6.35

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.46
Current EV/EBITDA
-14.62
Overvalued EV/EBITDA
1.55
Undervalued EV/EBITDA
-2.48

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
589.62
Current PS
468.84
Overvalued PS
960.08
Undervalued PS
219.17

Financials

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Frequently Asked Questions

What is Cardiff Oncology Inc (CRDF) stock price today?

The current price of CRDF is 1.78 USD — it has decreased -1.11

What is Cardiff Oncology Inc (CRDF)'s business?

Cardiff Oncology, Inc. is a clinical-stage biotechnology company. It is leveraging PLK1 inhibition, a well-validated oncology drug target, to develop novel therapies across a range of cancers with unmet medical need. It is focused on clinical programs in indications, such as RAS-mutated metastatic colorectal cancer (mCRC), and in investigator-initiated trials in metastatic pancreatic ductal adenocarcinoma (mPDAC), small cell lung cancer (SCLC), and triple negative breast cancer (TNBC). Its lead drug candidate, Onvansertib, is an oral, small-molecule drug candidate that is highly specific for PLK1 inhibition with a 24-hour half-life. It has other ongoing and planned clinical trials of onvansertib: one trial (CRDF-004) in first-line treatment in patients with RAS-mutated mCRC, and investigator-initiated trials in first-line mPDAC, relapsed SCLC and unresectable locally advanced or metastatic TNBC.

What is the price predicton of CRDF Stock?

Wall Street analysts forecast CRDF stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CRDF is13.67 USD with a low forecast of 10.00 USD and a high forecast of 19.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Cardiff Oncology Inc (CRDF)'s revenue for the last quarter?

Cardiff Oncology Inc revenue for the last quarter amounts to 243.00K USD, increased 60.93

What is Cardiff Oncology Inc (CRDF)'s earnings per share (EPS) for the last quarter?

Cardiff Oncology Inc. EPS for the last quarter amounts to -0.11 USD, decreased -50.00

How many employees does Cardiff Oncology Inc (CRDF). have?

Cardiff Oncology Inc (CRDF) has 31 emplpoyees as of April 21 2026.

What is Cardiff Oncology Inc (CRDF) market cap?

Today CRDF has the market capitalization of 121.69M USD.