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CRBU Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
1.806
Open
1.790
VWAP
1.74
Vol
1.27M
Mkt Cap
166.22M
Low
1.685
Amount
2.21M
EV/EBITDA(TTM)
--
Total Shares
96.64M
EV
32.67M
EV/OCF(TTM)
--
P/S(TTM)
14.90
Caribou Biosciences, Inc. is a clinical-stage clustered regularly interspaced short palindromic repeats (CRISPR) genome-editing biopharmaceutical company engaged in developing transformative therapies for patients with devastating diseases. The Company’s genome-editing platform, including its Cas12a chRDNA technology, enables superior precision to develop cell therapies that are armored to potentially improve activity against disease. Caribou is advancing a pipeline of off-the-shelf cell therapies from its CAR-T platform to offer broad access and rapid availability of treatments for patients with hematologic malignancies and autoimmune diseases. Its genome-editing platform, including its novel chRDNA technology, enables more precise genome editing of allogeneic cell therapies. It is advancing its pipeline of allogeneic CAR-T cell therapies with clinical development programs targeting the treatment of hematologic malignancies and autoimmune diseases.
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Events Timeline

(ET)
2026-03-05
16:30:00
Caribou Reports Q4 Revenue of $3.94M, Up 89% Year-over-Year
select
2025-11-12 (ET)
2025-11-12
17:24:15
Caribou Biosciences announces Q3 earnings per share of 30 cents, compared to a loss of 38 cents in the same period last year.
select
2025-11-11 (ET)
2025-11-11
16:27:07
Richard Pazdur Named Director of CDER by FDA
select
link
2025-11-03 (ET)
2025-11-03
07:15:53
Caribou Biosciences Reveals Findings from Phase 1 CaMMouflage Trial
select
2025-11-03
07:14:54
Caribou Biosciences Reveals Findings from Phase 1 ANTLER Trial of Vispa-cel
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News

seekingalpha
9.0
13:11 PMseekingalpha
Caribou Biosciences' CAR-T Therapy Receives FDA RMAT Designation
  • FDA Designation Milestone: Caribou Biosciences' CAR-T cell therapy, CB-011, has received the FDA's Regenerative Medicine Advanced Therapy (RMAT) designation, marking a significant milestone in the treatment of relapsed or refractory multiple myeloma.
  • Clinical Trial Results: Currently undergoing a Phase 1 trial named CaMMouflage, CB-011 has shown a remarkable 92% overall response rate in a review of 12 BCMA-naïve patients, indicating the therapy's potential effectiveness.
  • Accelerated Approval Benefits: With the RMAT designation, Caribou can benefit from the FDA's priority and rolling review processes, potentially expediting the market entry of CB-011 and leading to quicker returns for the company.
  • Positive Market Reaction: Following the FDA announcement, Caribou's stock rose approximately 9% in premarket trading, reflecting investor optimism regarding the prospects of its CAR-T therapy and further solidifying the company's position in the cell therapy market.
Newsfilter
9.0
12:42 PMNewsfilter
Caribou Biosciences Receives FDA RMAT Designation for CB-011
  • Promising Clinical Data: Caribou Biosciences' CB-011 demonstrated a 92% overall response rate (ORR) and a 75% complete response (CR) rate in a cohort of 12 BCMA-naïve patients with relapsed or refractory multiple myeloma, indicating significant potential to transform treatment outcomes for patients.
  • FDA Designation Accelerates Development: The FDA granted RMAT designation to CB-011, aimed at expediting its development process, highlighting the therapy's importance in addressing the unmet medical needs of multiple myeloma patients and potentially accelerating its path to market.
  • Favorable Safety Profile: CB-011 exhibited a manageable safety profile with no cases of graft-versus-host disease reported, although 80% of patients experienced neutropenia; this positive safety data supports its future clinical applications and market acceptance.
  • Positive Future Outlook: Caribou plans to report longer follow-up data in 2026 and engage in discussions with the FDA regarding the future clinical development of CB-011, reflecting the company's confidence in the therapy and its potential market impact.
seekingalpha
9.5
03-05seekingalpha
Caribou Bioscience Q4 Earnings Beat Expectations
  • Earnings Highlights: Caribou Bioscience reported a Q4 GAAP EPS of -$0.28, beating expectations by $0.04, indicating an improvement in profitability despite still being in the red.
  • Revenue Surge: The company achieved Q4 revenue of $3.94M, representing an 89.4% year-over-year increase and surpassing market expectations by $1.98M, reflecting strong product demand and enhanced market acceptance.
  • Cash Position: As of December 31, 2025, Caribou reported $142.8 million in cash, cash equivalents, and marketable securities, down from $249.4 million in 2024, highlighting challenges in cash management.
  • Future Outlook: Caribou expects its current cash reserves to fund its operational plans, including dose expansion for CB-011 and startup activities for the planned vispa-cel pivotal trial, projected to last into the second half of 2027, demonstrating confidence in future growth.
NASDAQ.COM
9.5
02-24NASDAQ.COM
Vir Biotechnology Reports Better-Than-Expected Quarterly Loss
  • Earnings Surprise: Vir Biotechnology reported a quarterly loss of $0.31 per share, better than the Zacks consensus estimate of a $0.42 loss, indicating improvements in cost management despite ongoing challenges.
  • Significant Revenue Growth: The company posted revenues of $64.07 million for the quarter, surpassing the Zacks consensus estimate by 243.23%, compared to $12.37 million a year ago, demonstrating positive progress in market demand recovery.
  • Stock Performance: Since the beginning of the year, Vir Biotechnology's shares have risen approximately 25.4%, significantly outperforming the S&P 500's gain of 0.9%, reflecting investor confidence in the company's future growth potential.
  • Future Outlook: Although the current EPS estimate stands at -$0.60 with revenues of $2.41 million, the industry rank is in the top 37% of over 250 Zacks industries, indicating a generally positive trend that may support stock performance.
Yahoo Finance
6.0
02-20Yahoo Finance
Caribou Biosciences Stock Analysis
  • Market Volatility: Caribou Biosciences (CRBU) is listed among the 7 most volatile stocks under $5 for day trading, indicating significant investor interest and potential short-term trading opportunities in this low-priced stock segment.
  • Sales Potential Forecast: Clear Street projects that Caribou's CB-011 may reach peak sales of $734 million by 2040, despite a low 20% chance of success, highlighting the balance of market potential against clinical risks.
  • Rating and Price Target: On February 2, 2026, Clear Street initiated coverage of Caribou with a 'Buy' rating and a $13 price target, primarily based on its upcoming CAR-T program, reflecting market confidence in the company's future developments.
  • Industry Dynamics: On January 6, 2026, BofA lowered Caribou's price target from $8 to $6 while maintaining a 'Buy' rating, indicating concerns over durability amidst a broader reset in U.S. biopharma valuations, which may affect investor sentiment.
seekingalpha
2.0
02-03seekingalpha
Clear Street Initiates Buy on Caribou Biosciences, Sees 790% Upside
  • Buy Rating Initiated: Clear Street has initiated coverage on Caribou Biosciences (CRBU) with a buy rating, citing the company's promising pipeline of off-the-shelf CAR-T therapies for cancer, which has led to a ~6% increase in shares during Tuesday trading.
  • Price Target Set: The firm has set a price target of $13, representing approximately 790% upside based on the February 2 close, reflecting strong confidence in the company's future performance.
  • Product Competitiveness: Analyst Bill Maughan noted that Caribou's candidates
Wall Street analysts forecast CRBU stock price to rise
5 Analyst Rating
Wall Street analysts forecast CRBU stock price to rise
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
6.00
Averages
8.00
High
10.00
Current: 0.000
sliders
Low
6.00
Averages
8.00
High
10.00
Evercore ISI
Outperform
maintain
$11 -> $13
AI Analysis
2026-03-09
Reason
Evercore ISI
Price Target
$11 -> $13
AI Analysis
2026-03-09
maintain
Outperform
Reason
Evercore ISI raised the firm's price target on Caribou Biosciences to $13 from $11 and keeps an Outperform rating on the shares. While CD19 and BCMA data look "promising," funding remains a hurdle for launching pivotal studies, the analyst tells investors.
Clear Street
NULL
to
Buy
initiated
$13
2026-02-02
Reason
Clear Street
Price Target
$13
2026-02-02
initiated
NULL
to
Buy
Reason
Clear Street initiated coverage of Caribou Biosciences with a Buy rating and $13 price target. Caribou is developing a pipeline of off-the-shelf allogeneic CAR-T cell therapies, including lead asset vispa-cel, the analyst tells investors. Vispa-cel is preparing to enter a registrational Phase 3 study in second line or later large B-cell lymphoma, notes the analyst, whose model includes vispa-cel peak sales of $992M in 2040 and 30% odds of success as well as CB-011 peak sales of $734M in 2040 and 20% odds of success.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for CRBU
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Valuation Metrics

The current forward P/E ratio for Caribou Biosciences Inc (CRBU.O) is -1.18, compared to its 5-year average forward P/E of -4.06. For a more detailed relative valuation and DCF analysis to assess Caribou Biosciences Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.06
Current PE
-1.18
Overvalued PE
0.01
Undervalued PE
-8.13

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.85
Current EV/EBITDA
-0.09
Overvalued EV/EBITDA
2.61
Undervalued EV/EBITDA
-6.32

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
31.17
Current PS
15.02
Overvalued PS
57.35
Undervalued PS
5.00

Financials

AI Analysis
Annual
Quarterly

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Whales Holding CRBU

K
Kynam Capital Management, LP
Holding
CRBU
-2.15%
3M Return

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Frequently Asked Questions

What is Caribou Biosciences Inc (CRBU) stock price today?

The current price of CRBU is 1.72 USD — it has decreased -3.37

What is Caribou Biosciences Inc (CRBU)'s business?

Caribou Biosciences, Inc. is a clinical-stage clustered regularly interspaced short palindromic repeats (CRISPR) genome-editing biopharmaceutical company engaged in developing transformative therapies for patients with devastating diseases. The Company’s genome-editing platform, including its Cas12a chRDNA technology, enables superior precision to develop cell therapies that are armored to potentially improve activity against disease. Caribou is advancing a pipeline of off-the-shelf cell therapies from its CAR-T platform to offer broad access and rapid availability of treatments for patients with hematologic malignancies and autoimmune diseases. Its genome-editing platform, including its novel chRDNA technology, enables more precise genome editing of allogeneic cell therapies. It is advancing its pipeline of allogeneic CAR-T cell therapies with clinical development programs targeting the treatment of hematologic malignancies and autoimmune diseases.

What is the price predicton of CRBU Stock?

Wall Street analysts forecast CRBU stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CRBU is8.00 USD with a low forecast of 6.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Caribou Biosciences Inc (CRBU)'s revenue for the last quarter?

Caribou Biosciences Inc revenue for the last quarter amounts to 3.94M USD, increased 89.74

What is Caribou Biosciences Inc (CRBU)'s earnings per share (EPS) for the last quarter?

Caribou Biosciences Inc. EPS for the last quarter amounts to -0.28 USD, decreased -28.21

How many employees does Caribou Biosciences Inc (CRBU). have?

Caribou Biosciences Inc (CRBU) has 97 emplpoyees as of March 31 2026.

What is Caribou Biosciences Inc (CRBU) market cap?

Today CRBU has the market capitalization of 166.22M USD.