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CLNN Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
6.760
Open
6.580
VWAP
6.64
Vol
94.73K
Mkt Cap
85.49M
Low
6.470
Amount
629.04K
EV/EBITDA(TTM)
--
Total Shares
12.78M
EV
96.22M
EV/OCF(TTM)
--
P/S(TTM)
517.74
Clene Inc. is a clinical-stage pharmaceutical company, which is engaged in discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. The CSN therapeutics are comprised of atoms of transition elements that, when assembled in nanocrystal form, possess unusually high, unique catalytic activities that do not present in those same elements in bulk form. CNM-Au8, the lead drug asset, is a concentrated aqueous suspension of catalytically active, clean-surfaced, faceted gold nanocrystals for the treatment of ALS, MS, and PD. CNM-Au8's mechanism of action targets mitochondrial dysfunction by catalyzing the production of nicotinamide adenine dinucleotide. Its CNM-ZnAg is an antiviral and antibacterial agent comprised of zinc (Zn2+) and silver (Ag+) ions in an aqueous solution to treat infectious disease and to provide immune support for symptom resolution.
Show More

Events Timeline

(ET)
2026-05-14
08:20:00
Clene Reports Q1 Revenue of $15 Million, Below Expectations
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2026-05-04 (ET)
2026-05-04
08:30:00
Clene Receives Final Meeting Minutes from FDA, Plans to Submit ALS NDA in 2026
select
2026-03-12 (ET)
2026-03-12
08:10:00
Clene Reports FY25 Revenue of $200k, Exceeding Expectations
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2026-02-24 (ET)
2026-02-24
08:10:00
Clene Outlines Key Milestones for CNM-Au8 in 2026
select
2026-01-12 (ET)
2026-01-12
09:10:00
Clene Granted In-Person Meeting by FDA
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2026-01-09 (ET)
2026-01-09
08:40:00
Clene Announces Registered Direct Offering Over $28M
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2025-12-03 (ET)
2025-12-03
08:20:00
Clene Completes Biomarker Analyses for ALS Treatment CNM-Au8
select

News

stocktwits
9.0
05-15stocktwits
Clene Plans to Submit ALS Drug Application
  • Drug Application Plans: Clene announced plans to submit a New Drug Application for its ALS candidate CNM-Au8 in Q3 2026 under the FDA’s accelerated approval pathway, aiming to provide new treatment options for ALS patients, although analysts express skepticism about its approval prospects.
  • Positive FDA Feedback: Clene received encouraging feedback regarding neurofilament light chain (NfL) data in a recent meeting with the FDA, indicating that NfL, a key biomarker of neuronal damage, may support accelerated approval, but confirmatory trials will be required to verify efficacy.
  • Analyst Insights: Roth Capital analyst reiterated a ‘Buy’ rating and a $30 price target for Clene, despite doubts about whether the magnitude of NfL change will drive approval, reflecting the complexities and competitive pressures in the ALS treatment market.
  • Market Reaction: Clene's shares rose 8% during regular trading but fell 3% in after-hours trading following the analyst's pessimistic comments, indicating investor concerns over the drug's approval prospects, with retail sentiment remaining in the 'bearish' territory.
seekingalpha
9.5
05-14seekingalpha
Clene Reports Q1 2026 Financial Results with Significant Cash Position
  • Financial Performance: Clene reported a Q1 2026 GAAP EPS of -$0.69 with revenue of only $0.01 million, indicating significant challenges in revenue generation that may impact investor confidence.
  • Cash Position: As of March 31, 2026, Clene's cash and cash equivalents totaled $5.9 million, an increase from $5.2 million as of December 31, 2025, reflecting improvements in the company's cash management.
  • Funding Outlook: Clene expects that its resources, including $7.0 million in gross proceeds from its May 2026 registered direct offering, will provide operational runway into Q4 2026, demonstrating proactive financing efforts.
  • Future Prospects: With potential future warrant exercises tied to FDA NDA acceptance amounting to approximately $7.0 million, Clene's cash runway is projected to extend into 2027, enhancing the company's growth potential.
seekingalpha
8.5
05-05seekingalpha
Clene Prices $7 Million Direct Stock Offering
  • Offering Details: Clene and its wholly owned subsidiary, Clene Nanomedicine, announced a direct offering of 1 million shares at $7.00 per share to a single investor, with gross proceeds expected to be around $7 million, indicating the company's active engagement in capital markets.
  • Use of Proceeds: The net proceeds from this offering will be utilized alongside existing cash for general corporate purposes, reflecting a prudent financial strategy aimed at supporting future operations and growth.
  • Expected Closing Date: The offering is anticipated to close on or about May 6, 2026, showcasing the company's proactive management of future liquidity to ensure ongoing business operations.
  • Market Reaction Outlook: While this offering may dilute existing shareholders' stakes, the company strengthens its capital base through this move, potentially providing greater growth opportunities for investors in the future.
stocktwits
8.5
05-04stocktwits
Clene Plans NDA Submission by Q3 2026 for ALS Treatment
  • Positive FDA Feedback: Clene's experimental ALS treatment CNM-Au8 received encouraging feedback from the FDA, which indicated that data on the NfL biomarker may support an accelerated New Drug Application, highlighting the drug's potential in nerve damage and positively impacting Clene's market outlook.
  • Strong Safety Profile: CNM-Au8 has demonstrated a favorable safety profile with no serious treatment-related side effects reported, which not only boosts investor confidence in the drug but also lays a solid foundation for future clinical trials.
  • Strong Market Reaction: Clene's shares surged over 8% on Monday, reflecting investor optimism following the FDA news, and reached their highest levels in 2026, indicating strong market interest in the company's future developments.
  • Retail Investor Sentiment Shift: On Stocktwits, retail investor sentiment for Clene shifted from 'bullish' to 'extremely bullish', accompanied by extremely high message volumes, indicating increased confidence in the likelihood of NDA acceptance, although some investors remain skeptical about its true significance.
Newsfilter
8.5
05-04Newsfilter
Clene Plans NDA Submission for ALS Drug CNM-Au8
  • FDA Support for NDA: The FDA indicated that Clene's proposed data for CNM-Au8 may support its New Drug Application (NDA) submission under the accelerated approval pathway, presenting a significant opportunity for the company in ALS treatment advancement.
  • Biomarker Data Importance: The FDA emphasized that changes in the neurofilament light (NfL) biomarker could serve as a reasonably likely surrogate endpoint, requiring Clene to demonstrate the connection between NfL changes and clinical benefits to strengthen its NDA.
  • Clear Submission Timeline: Clene plans to submit its NDA in the third quarter of 2026, marking a crucial milestone in the development of its ALS drug and potentially accelerating patient access to new therapies.
  • Clinical Trial Support: The NDA submission will be supported by data from the Phase 2 HEALEY ALS Platform Trial and RESCUE-ALS Trial, which indicate that reductions in NfL levels are associated with longer survival, further enhancing the market potential of CNM-Au8.
seekingalpha
9.5
03-12seekingalpha
Clene Reports FY 2025 Financial Results with Significant Losses
  • Earnings Report: Clene's FY 2025 GAAP EPS stands at -$2.65, indicating significant challenges in profitability that could undermine investor confidence and future financing capabilities.
  • Revenue Performance: The company reported revenue of only $0.2 million, falling far short of market expectations, suggesting insufficient market acceptance of its products or services, which may lead to slowed future growth.
  • Liquidity Position: As of December 31, 2025, Clene's cash and cash equivalents totaled $5.2 million, a substantial decrease from $12.2 million in 2024, highlighting pressures in cash management and operational sustainability.
  • Financing Initiative: Clene announced a registered direct offering of over $28 million, aimed at strengthening its capital base, although this may dilute existing shareholders' stakes and impact shareholder value.
Wall Street analysts forecast CLNN stock price to rise
5 Analyst Rating
Wall Street analysts forecast CLNN stock price to rise
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
30.00
Averages
30.40
High
31.00
Current: 0.000
sliders
Low
30.00
Averages
30.40
High
31.00
Roth Capital
Jonathan Aschoff
Buy
maintain
$30
AI Analysis
2026-05-14
Reason
Roth Capital
Jonathan Aschoff
Price Target
$30
AI Analysis
2026-05-14
maintain
Buy
Reason
Roth Capital analyst Jonathan Aschoff reiterated a Buy rating and $30 price target on Clene, noting that the company ended Q1 with $12.4M in pro forma cash, enough funding into Q4, with a potential additional $22M in milestone-based funding tranches able to fund operations well into 2027. The FDA agreeing to receive Clene's accelerated approval NDA for CNM-Au8 in treating ALS is a positive development, but the firm does not believe that the magnitude of change in neurofilament light, or NfL, will drive approval. The firm added that despite the dire ALS medical need, the much smaller NfL reduction with CNM-Au8 versus Qalsody stokes its pessimism.
Canaccord
Buy
maintain
$48 -> $50
2026-05-08
Reason
Canaccord
Price Target
$48 -> $50
2026-05-08
maintain
Buy
Reason
Canaccord raised the firm's price target on Clene to $50 from $48 and keeps a Buy rating on the shares. The firm noted the company recently announced that it plans to file a new drug application (NDA) with the FDA in 3Q26 for CNM-Au8 (nanocrystalline gold) for amyotrophic lateral sclerosis (ALS) under the accelerated approval pathway. Canaccord believes the shares are undervalued for a company close to filing in a high unmet need indication.
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Valuation Metrics

The current forward P/E ratio for Clene Inc (CLNN.O) is 0.00, compared to its 5-year average forward P/E of -3.49. For a more detailed relative valuation and DCF analysis to assess Clene Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.49
Current PE
0.00
Overvalued PE
-0.18
Undervalued PE
-6.80

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.61
Current EV/EBITDA
-0.04
Overvalued EV/EBITDA
-0.46
Undervalued EV/EBITDA
-2.76

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
343.73
Current PS
4.35
Overvalued PS
735.55
Undervalued PS
-48.10

Financials

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Frequently Asked Questions

What is Clene Inc (CLNN) stock price today?

The current price of CLNN is 6.69 USD — it has increased 1.83

What is Clene Inc (CLNN)'s business?

Clene Inc. is a clinical-stage pharmaceutical company, which is engaged in discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. The CSN therapeutics are comprised of atoms of transition elements that, when assembled in nanocrystal form, possess unusually high, unique catalytic activities that do not present in those same elements in bulk form. CNM-Au8, the lead drug asset, is a concentrated aqueous suspension of catalytically active, clean-surfaced, faceted gold nanocrystals for the treatment of ALS, MS, and PD. CNM-Au8's mechanism of action targets mitochondrial dysfunction by catalyzing the production of nicotinamide adenine dinucleotide. Its CNM-ZnAg is an antiviral and antibacterial agent comprised of zinc (Zn2+) and silver (Ag+) ions in an aqueous solution to treat infectious disease and to provide immune support for symptom resolution.

What is the price predicton of CLNN Stock?

Wall Street analysts forecast CLNN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CLNN is30.40 USD with a low forecast of 30.00 USD and a high forecast of 31.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Clene Inc (CLNN)'s revenue for the last quarter?

Clene Inc revenue for the last quarter amounts to 15.00K USD, decreased -81.48

What is Clene Inc (CLNN)'s earnings per share (EPS) for the last quarter?

Clene Inc. EPS for the last quarter amounts to -0.69 USD, increased 666.67

How many employees does Clene Inc (CLNN). have?

Clene Inc (CLNN) has 79 emplpoyees as of May 28 2026.

What is Clene Inc (CLNN) market cap?

Today CLNN has the market capitalization of 85.49M USD.