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CLNN Overview

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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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ET
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Intellectia

Loading chart...

High
7.300
Open
7.080
VWAP
7.13
Vol
117.13K
Mkt Cap
84.33M
Low
6.850
Amount
834.71K
EV/EBITDA(TTM)
--
Total Shares
11.78M
EV
103.92M
EV/OCF(TTM)
--
P/S(TTM)
352.81
Clene Inc. is a clinical-stage pharmaceutical company, which is engaged in discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. The CSN therapeutics are comprised of atoms of transition elements that, when assembled in nanocrystal form, possess unusually high, unique catalytic activities that do not present in those same elements in bulk form. CNM-Au8, the lead drug asset, is a concentrated aqueous suspension of catalytically active, clean-surfaced, faceted gold nanocrystals for the treatment of ALS, MS, and PD. CNM-Au8's mechanism of action targets mitochondrial dysfunction by catalyzing the production of nicotinamide adenine dinucleotide. Its CNM-ZnAg is an antiviral and antibacterial agent comprised of zinc (Zn2+) and silver (Ag+) ions in an aqueous solution to treat infectious disease and to provide immune support for symptom resolution.
Show More

Events Timeline

(ET)
2026-05-04
08:30:00
Clene Receives Final Meeting Minutes from FDA, Plans to Submit ALS NDA in 2026
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2026-03-12 (ET)
2026-03-12
08:10:00
Clene Reports FY25 Revenue of $200k, Exceeding Expectations
select
2026-02-24 (ET)
2026-02-24
08:10:00
Clene Outlines Key Milestones for CNM-Au8 in 2026
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2026-01-12 (ET)
2026-01-12
09:10:00
Clene Granted In-Person Meeting by FDA
select
2026-01-09 (ET)
2026-01-09
08:40:00
Clene Announces Registered Direct Offering Over $28M
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2025-12-03 (ET)
2025-12-03
08:20:00
Clene Completes Biomarker Analyses for ALS Treatment CNM-Au8
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2025-11-13 (ET)
2025-11-13
08:10:01
Clene anticipates funding to last until the second quarter of 2026.
select
2025-11-13
08:09:13
Clene Announces Q3 Earnings Per Share of 85 Cents, Exceeding Consensus Estimate of 56 Cents
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News

seekingalpha
8.5
05-05seekingalpha
PinnedClene Prices $7 Million Direct Stock Offering
  • Offering Details: Clene and its wholly owned subsidiary, Clene Nanomedicine, announced a direct offering of 1 million shares at $7.00 per share to a single investor, with gross proceeds expected to be around $7 million, indicating the company's active engagement in capital markets.
  • Use of Proceeds: The net proceeds from this offering will be utilized alongside existing cash for general corporate purposes, reflecting a prudent financial strategy aimed at supporting future operations and growth.
  • Expected Closing Date: The offering is anticipated to close on or about May 6, 2026, showcasing the company's proactive management of future liquidity to ensure ongoing business operations.
  • Market Reaction Outlook: While this offering may dilute existing shareholders' stakes, the company strengthens its capital base through this move, potentially providing greater growth opportunities for investors in the future.
stocktwits
8.5
05-04stocktwits
Clene Plans NDA Submission by Q3 2026 for ALS Treatment
  • Positive FDA Feedback: Clene's experimental ALS treatment CNM-Au8 received encouraging feedback from the FDA, which indicated that data on the NfL biomarker may support an accelerated New Drug Application, highlighting the drug's potential in nerve damage and positively impacting Clene's market outlook.
  • Strong Safety Profile: CNM-Au8 has demonstrated a favorable safety profile with no serious treatment-related side effects reported, which not only boosts investor confidence in the drug but also lays a solid foundation for future clinical trials.
  • Strong Market Reaction: Clene's shares surged over 8% on Monday, reflecting investor optimism following the FDA news, and reached their highest levels in 2026, indicating strong market interest in the company's future developments.
  • Retail Investor Sentiment Shift: On Stocktwits, retail investor sentiment for Clene shifted from 'bullish' to 'extremely bullish', accompanied by extremely high message volumes, indicating increased confidence in the likelihood of NDA acceptance, although some investors remain skeptical about its true significance.
Newsfilter
8.5
05-04Newsfilter
Clene Plans NDA Submission for ALS Drug CNM-Au8
  • FDA Support for NDA: The FDA indicated that Clene's proposed data for CNM-Au8 may support its New Drug Application (NDA) submission under the accelerated approval pathway, presenting a significant opportunity for the company in ALS treatment advancement.
  • Biomarker Data Importance: The FDA emphasized that changes in the neurofilament light (NfL) biomarker could serve as a reasonably likely surrogate endpoint, requiring Clene to demonstrate the connection between NfL changes and clinical benefits to strengthen its NDA.
  • Clear Submission Timeline: Clene plans to submit its NDA in the third quarter of 2026, marking a crucial milestone in the development of its ALS drug and potentially accelerating patient access to new therapies.
  • Clinical Trial Support: The NDA submission will be supported by data from the Phase 2 HEALEY ALS Platform Trial and RESCUE-ALS Trial, which indicate that reductions in NfL levels are associated with longer survival, further enhancing the market potential of CNM-Au8.
seekingalpha
9.5
03-12seekingalpha
Clene Reports FY 2025 Financial Results with Significant Losses
  • Earnings Report: Clene's FY 2025 GAAP EPS stands at -$2.65, indicating significant challenges in profitability that could undermine investor confidence and future financing capabilities.
  • Revenue Performance: The company reported revenue of only $0.2 million, falling far short of market expectations, suggesting insufficient market acceptance of its products or services, which may lead to slowed future growth.
  • Liquidity Position: As of December 31, 2025, Clene's cash and cash equivalents totaled $5.2 million, a substantial decrease from $12.2 million in 2024, highlighting pressures in cash management and operational sustainability.
  • Financing Initiative: Clene announced a registered direct offering of over $28 million, aimed at strengthening its capital base, although this may dilute existing shareholders' stakes and impact shareholder value.
Yahoo Finance
8.5
02-24Yahoo Finance
Clene Inc. Outlines Key Milestones for 2026
  • Sufficient Funding: Clene Inc. completed an oversubscribed registered direct offering of over $28 million, with an initial tranche of over $6 million expected to fund operations into the fourth quarter of 2026, ensuring capital availability ahead of a potential New Drug Application (NDA) acceptance decision.
  • FDA Meeting Scheduled: The company plans an in-person Type C meeting with the FDA by the end of Q1 2026 to discuss data submitted for CNM-Au8 in late 2025, which is expected to provide critical feedback for the NDA submission and accelerate the approval process.
  • Clinical Data Support: CNM-Au8 has demonstrated significant survival benefits and declines in biomarkers in ALS patients, supporting its candidacy for accelerated approval, with ongoing discussions with the FDA indicating alignment with regulatory expectations.
  • Upcoming Trial Plans: Clene intends to initiate the confirmatory Phase 3 RESTORE-ALS trial later in 2026 to validate the survival benefits observed with CNM-Au8, meeting FDA requirements for the accelerated approval pathway and further solidifying its position in neurodegenerative disease treatment.
Globenewswire
1.0
01-16Globenewswire
Clene Inc. to Present at Emerging Growth Conference on January 21, 2026
  • Presentation Schedule: Clene Inc. will present a corporate update at the Emerging Growth Conference on January 21, 2026, at 3:10 p.m. ET, showcasing its latest advancements in treating neurodegenerative diseases, which is expected to attract significant investor interest.
  • Innovation Showcase: Clene focuses on improving mitochondrial health and protecting neuronal function, particularly targeting amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS), with its investigational therapy CNM-Au8® aiming to enhance central nervous system cell survival through mitochondrial function targeting.
  • Webcast Availability: The presentation will be available via a webcast on Clene's website under the “Events” section, and a replay will also be accessible through the conference portal and YouTube channel, ensuring that investors unable to attend live can still access the information.
  • Investor Relations Enhancement: The Emerging Growth Conference provides Clene with an effective platform to present its innovative products and services to potential individual and institutional investors, further strengthening the company's market presence in the biopharmaceutical sector.
Wall Street analysts forecast CLNN stock price to rise
5 Analyst Rating
Wall Street analysts forecast CLNN stock price to rise
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
30.00
Averages
30.40
High
31.00
Current: 0.000
sliders
Low
30.00
Averages
30.40
High
31.00
Maxim
Naz Rahman
Buy
maintain
$20 -> $30
AI Analysis
2025-12-03
Reason
Maxim
Naz Rahman
Price Target
$20 -> $30
AI Analysis
2025-12-03
maintain
Buy
Reason
Maxim analyst Naz Rahman raised the firm's price target on Clene to $30 from $20 and keeps a Buy rating on the shares after the company and its wholly owned subsidiary Clene Nanomedicine announced completion of the FDA-recommended biomarker analyses for CNM-Au8 in people living with ALS. The results demonstrate statistically significant reductions in both neurofilament light, NfL, and glial fibrillary acidic protein, GFAP, which "clears way" for an NDA filing, the analyst says.
Benchmark
Buy
downgrade
$33 -> $31
2025-09-10
Reason
Benchmark
Price Target
$33 -> $31
2025-09-10
downgrade
Buy
Reason
Benchmark lowered the firm's price target on Clene to $31 from $33 and keeps a Buy rating on the shares. Having obtained agreement from the FDA regarding the statistical analysis plan, Clene continues to work toward an anticipated NDA submission in Q4 for CNM-Au-8 in the treatment of ALS, the analyst noted while updating the firm's model.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for CLNN
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Valuation Metrics

The current forward P/E ratio for Clene Inc (CLNN.O) is 0.00, compared to its 5-year average forward P/E of -3.63. For a more detailed relative valuation and DCF analysis to assess Clene Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.63
Current PE
0.00
Overvalued PE
-0.13
Undervalued PE
-7.12

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.61
Current EV/EBITDA
-0.03
Overvalued EV/EBITDA
-0.46
Undervalued EV/EBITDA
-2.76

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
361.48
Current PS
2.06
Overvalued PS
771.08
Undervalued PS
-48.12

Financials

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Frequently Asked Questions

What is Clene Inc (CLNN) stock price today?

The current price of CLNN is 7.23 USD — it has increased 0.98

What is Clene Inc (CLNN)'s business?

Clene Inc. is a clinical-stage pharmaceutical company, which is engaged in discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. The CSN therapeutics are comprised of atoms of transition elements that, when assembled in nanocrystal form, possess unusually high, unique catalytic activities that do not present in those same elements in bulk form. CNM-Au8, the lead drug asset, is a concentrated aqueous suspension of catalytically active, clean-surfaced, faceted gold nanocrystals for the treatment of ALS, MS, and PD. CNM-Au8's mechanism of action targets mitochondrial dysfunction by catalyzing the production of nicotinamide adenine dinucleotide. Its CNM-ZnAg is an antiviral and antibacterial agent comprised of zinc (Zn2+) and silver (Ag+) ions in an aqueous solution to treat infectious disease and to provide immune support for symptom resolution.

What is the price predicton of CLNN Stock?

Wall Street analysts forecast CLNN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CLNN is30.40 USD with a low forecast of 30.00 USD and a high forecast of 31.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Clene Inc (CLNN)'s revenue for the last quarter?

Clene Inc revenue for the last quarter amounts to 77.00K USD, decreased -15.38

What is Clene Inc (CLNN)'s earnings per share (EPS) for the last quarter?

Clene Inc. EPS for the last quarter amounts to -0.86 USD, decreased -46.58

How many employees does Clene Inc (CLNN). have?

Clene Inc (CLNN) has 79 emplpoyees as of May 07 2026.

What is Clene Inc (CLNN) market cap?

Today CLNN has the market capitalization of 84.33M USD.