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CLNN Overview

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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
5.980
Open
5.640
VWAP
5.77
Vol
67.28K
Mkt Cap
67.49M
Low
5.590
Amount
387.96K
EV/EBITDA(TTM)
--
Total Shares
11.78M
EV
79.92M
EV/OCF(TTM)
--
P/S(TTM)
282.34
Clene Inc. is a late clinical-stage biopharmaceutical company focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, including amyotrophic lateral sclerosis, Parkinson's disease, and multiple sclerosis. It specializes in the discovery, development, and commercialization of clean-surfaced nanotechnology (CSN) therapeutics. CNM-Au8, the lead asset, is a concentrated aqueous suspension of catalytically active, clean-surfaced, faceted gold nanocrystals. CNM-Au8’s mechanism of action targets mitochondrial dysfunction by catalyzing the production of nicotinamide adenine dinucleotide. Its CNM-ZnAg is a broad-spectrum antiviral, antibacterial agent comprised of zinc (Zn2+) and silver (Ag+) ions under development to treat infectious disease and to provide immune support for symptom resolution. Its CNM-AgZn17 is a gel polymer suspension of Zn2+ and Ag+ under development for the treatment of infectious diseases and to support wound healing.
Show More

Events Timeline

(ET)
2026-03-12
08:10:00
Clene Reports FY25 Revenue of $200k, Exceeding Expectations
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2026-02-24 (ET)
2026-02-24
08:10:00
Clene Outlines Key Milestones for CNM-Au8 in 2026
select
2026-01-12 (ET)
2026-01-12
09:10:00
Clene Granted In-Person Meeting by FDA
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2026-01-09 (ET)
2026-01-09
08:40:00
Clene Announces Registered Direct Offering Over $28M
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2025-12-03 (ET)
2025-12-03
08:20:00
Clene Completes Biomarker Analyses for ALS Treatment CNM-Au8
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2025-11-13 (ET)
2025-11-13
08:10:01
Clene anticipates funding to last until the second quarter of 2026.
select
2025-11-13
08:09:13
Clene Announces Q3 Earnings Per Share of 85 Cents, Exceeding Consensus Estimate of 56 Cents
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News

seekingalpha
9.5
03-12seekingalpha
Clene Reports FY 2025 Financial Results with Significant Losses
  • Earnings Report: Clene's FY 2025 GAAP EPS stands at -$2.65, indicating significant challenges in profitability that could undermine investor confidence and future financing capabilities.
  • Revenue Performance: The company reported revenue of only $0.2 million, falling far short of market expectations, suggesting insufficient market acceptance of its products or services, which may lead to slowed future growth.
  • Liquidity Position: As of December 31, 2025, Clene's cash and cash equivalents totaled $5.2 million, a substantial decrease from $12.2 million in 2024, highlighting pressures in cash management and operational sustainability.
  • Financing Initiative: Clene announced a registered direct offering of over $28 million, aimed at strengthening its capital base, although this may dilute existing shareholders' stakes and impact shareholder value.
Yahoo Finance
8.5
02-24Yahoo Finance
Clene Inc. Outlines Key Milestones for 2026
  • Sufficient Funding: Clene Inc. completed an oversubscribed registered direct offering of over $28 million, with an initial tranche of over $6 million expected to fund operations into the fourth quarter of 2026, ensuring capital availability ahead of a potential New Drug Application (NDA) acceptance decision.
  • FDA Meeting Scheduled: The company plans an in-person Type C meeting with the FDA by the end of Q1 2026 to discuss data submitted for CNM-Au8 in late 2025, which is expected to provide critical feedback for the NDA submission and accelerate the approval process.
  • Clinical Data Support: CNM-Au8 has demonstrated significant survival benefits and declines in biomarkers in ALS patients, supporting its candidacy for accelerated approval, with ongoing discussions with the FDA indicating alignment with regulatory expectations.
  • Upcoming Trial Plans: Clene intends to initiate the confirmatory Phase 3 RESTORE-ALS trial later in 2026 to validate the survival benefits observed with CNM-Au8, meeting FDA requirements for the accelerated approval pathway and further solidifying its position in neurodegenerative disease treatment.
Globenewswire
1.0
01-16Globenewswire
Clene Inc. to Present at Emerging Growth Conference on January 21, 2026
  • Presentation Schedule: Clene Inc. will present a corporate update at the Emerging Growth Conference on January 21, 2026, at 3:10 p.m. ET, showcasing its latest advancements in treating neurodegenerative diseases, which is expected to attract significant investor interest.
  • Innovation Showcase: Clene focuses on improving mitochondrial health and protecting neuronal function, particularly targeting amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS), with its investigational therapy CNM-Au8® aiming to enhance central nervous system cell survival through mitochondrial function targeting.
  • Webcast Availability: The presentation will be available via a webcast on Clene's website under the “Events” section, and a replay will also be accessible through the conference portal and YouTube channel, ensuring that investors unable to attend live can still access the information.
  • Investor Relations Enhancement: The Emerging Growth Conference provides Clene with an effective platform to present its innovative products and services to potential individual and institutional investors, further strengthening the company's market presence in the biopharmaceutical sector.
Newsfilter
1.0
01-16Newsfilter
Clene Inc. to Present at Emerging Growth Conference on January 21, 2026
  • Presentation Schedule: Clene Inc. will present a corporate update at the Emerging Growth Conference on January 21, 2026, at 3:10 p.m. ET, which is expected to attract significant investor interest in its new products and services.
  • Webcast Availability: The presentation will be available via webcast on Clene's website under the 'Events' section, and a replay will also be accessible through the conference portal and the Emerging Growth YouTube channel, ensuring investors can access the information at their convenience.
  • Company Background: Clene Inc. is a clinical-stage biopharmaceutical company focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, including amyotrophic lateral sclerosis and multiple sclerosis, showcasing its innovative potential in the biopharmaceutical sector.
  • Product Development Highlight: Its investigational therapy CNM-Au8® is a first-in-class treatment aimed at enhancing the survival and function of central nervous system cells by targeting mitochondrial function and the NAD pathway, indicating promising therapeutic prospects for neurodegenerative diseases.
NASDAQ.COM
2.0
01-14NASDAQ.COM
China SXT Pharmaceuticals (SXTC) Closes $10 Million Offering, Stock Rises 17.4%
  • Successful Financing: China SXT Pharmaceuticals, Inc. announced the closing of a registered direct offering valued at approximately $10 million, selling 66,666,666 Class A ordinary shares at $0.15 each to a single investor, thereby strengthening its balance sheet and boosting investor confidence.
  • Financial Guidance: TG Therapeutics reported preliminary U.S. net product revenue for its multiple sclerosis therapy BRIUMVI for Q4 and full-year 2025, with shares rising 6.99% to $29.82, showcasing the company's growth potential.
  • FDA Review Progress: Argenx SE's supplemental Biologics License Application for VYVGART, aimed at treating adults with acetylcholine receptor antibody seronegative generalized myasthenia gravis, has been accepted for priority review by the FDA, with a target action date of May 10, 2026, indicating potential for expanded indications.
  • Market Trends: Cosmos Health Inc. saw its stock rise 6.09% to $0.4961 despite no specific news, reflecting speculative interest and momentum trading in the micro-cap healthcare sector.
Globenewswire
9.0
01-12Globenewswire
Clene Inc. Receives FDA Approval for In-Person Meeting in 2026, NfL Reductions Linked to Lower ALS Mortality Risk
  • FDA Meeting Approval: Clene Inc. has received FDA approval for an in-person Type C meeting in Q1 2026 to discuss the association of NfL biomarkers with ALS patient survival, marking a significant step in the company's accelerated approval pathway.
  • NfL Reduction and Survival Link: In the HEALEY ALS Platform Trial, CNM-Au8 treatment resulted in approximately 10% reduction in NfL levels, significantly associated with an 8-13% lower mortality risk, indicating potential clinical benefits in rapidly progressive ALS.
  • IGFBP7 Biomarker Discovery: The decline in IGFBP7 levels was strongly associated with a 78% reduction in mortality risk among responders to CNM-Au8 treatment, further supporting the importance of this biomarker in ALS therapy and potentially guiding future treatment strategies.
  • Clinical Data Support: Clene's pre-meeting briefing package includes statistically significant reductions in NfL and GFAP, suggesting that changes in these biomarkers may predict clinical benefits for ALS patients, enhancing the company's competitive position in the biopharmaceutical sector.
Wall Street analysts forecast CLNN stock price to rise
5 Analyst Rating
Wall Street analysts forecast CLNN stock price to rise
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
30.00
Averages
30.40
High
31.00
Current: 0.000
sliders
Low
30.00
Averages
30.40
High
31.00
Maxim
Naz Rahman
Buy
maintain
$20 -> $30
AI Analysis
2025-12-03
Reason
Maxim
Naz Rahman
Price Target
$20 -> $30
AI Analysis
2025-12-03
maintain
Buy
Reason
Maxim analyst Naz Rahman raised the firm's price target on Clene to $30 from $20 and keeps a Buy rating on the shares after the company and its wholly owned subsidiary Clene Nanomedicine announced completion of the FDA-recommended biomarker analyses for CNM-Au8 in people living with ALS. The results demonstrate statistically significant reductions in both neurofilament light, NfL, and glial fibrillary acidic protein, GFAP, which "clears way" for an NDA filing, the analyst says.
Benchmark
Buy
downgrade
$33 -> $31
2025-09-10
Reason
Benchmark
Price Target
$33 -> $31
2025-09-10
downgrade
Buy
Reason
Benchmark lowered the firm's price target on Clene to $31 from $33 and keeps a Buy rating on the shares. Having obtained agreement from the FDA regarding the statistical analysis plan, Clene continues to work toward an anticipated NDA submission in Q4 for CNM-Au-8 in the treatment of ALS, the analyst noted while updating the firm's model.
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Valuation Metrics

The current forward P/E ratio for Clene Inc (CLNN.O) is -2.49, compared to its 5-year average forward P/E of -4.03. For a more detailed relative valuation and DCF analysis to assess Clene Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.03
Current PE
-2.49
Overvalued PE
0.37
Undervalued PE
-8.43

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.68
Current EV/EBITDA
-2.06
Overvalued EV/EBITDA
-0.56
Undervalued EV/EBITDA
-2.81

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
422.93
Current PS
235.77
Overvalued PS
887.80
Undervalued PS
-41.95

Financials

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Frequently Asked Questions

What is Clene Inc (CLNN) stock price today?

The current price of CLNN is 5.73 USD — it has increased 1.06

What is Clene Inc (CLNN)'s business?

Clene Inc. is a late clinical-stage biopharmaceutical company focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, including amyotrophic lateral sclerosis, Parkinson's disease, and multiple sclerosis. It specializes in the discovery, development, and commercialization of clean-surfaced nanotechnology (CSN) therapeutics. CNM-Au8, the lead asset, is a concentrated aqueous suspension of catalytically active, clean-surfaced, faceted gold nanocrystals. CNM-Au8’s mechanism of action targets mitochondrial dysfunction by catalyzing the production of nicotinamide adenine dinucleotide. Its CNM-ZnAg is a broad-spectrum antiviral, antibacterial agent comprised of zinc (Zn2+) and silver (Ag+) ions under development to treat infectious disease and to provide immune support for symptom resolution. Its CNM-AgZn17 is a gel polymer suspension of Zn2+ and Ag+ under development for the treatment of infectious diseases and to support wound healing.

What is the price predicton of CLNN Stock?

Wall Street analysts forecast CLNN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CLNN is30.40 USD with a low forecast of 30.00 USD and a high forecast of 31.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Clene Inc (CLNN)'s revenue for the last quarter?

Clene Inc revenue for the last quarter amounts to 15.00K USD, decreased -82.76

What is Clene Inc (CLNN)'s earnings per share (EPS) for the last quarter?

Clene Inc. EPS for the last quarter amounts to -0.85 USD, decreased -30.33

How many employees does Clene Inc (CLNN). have?

Clene Inc (CLNN) has 75 emplpoyees as of March 25 2026.

What is Clene Inc (CLNN) market cap?

Today CLNN has the market capitalization of 67.49M USD.