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CLDX Should I Buy

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Intellectia

Should You Buy Celldex Therapeutics Inc (CLDX) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
33.240
1 Day change
-1.25%
52 Week Range
35.790
Analysis Updated At
2026/04/24
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Given the investor's beginner level, long-term investment preference, and available capital, Celldex Therapeutics Inc (CLDX) is not a strong buy at this moment. The technical indicators are mixed, options data shows neutral sentiment, and the company's financial performance is weak. While there are positive catalysts in the form of analyst upgrades and upcoming trial data, the lack of immediate trading signals and the company's recent financial struggles suggest holding off on investment for now.

Technical Analysis

The MACD is below 0 and negatively expanding, indicating bearish momentum. RSI is neutral at 50.655, showing no clear trend. Moving averages are bullish (SMA_5 > SMA_20 > SMA_200), but the stock is trading below its pivot point of 33.813, with key support at 32.352 and resistance at 35.274.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
6
Buy
7

Positive Catalysts

  • Analysts have upgraded the stock with higher price targets, citing faster-than-expected trial enrollments and upcoming data readouts for barzolvolimab and other programs. The stock is entering a catalyst-rich period in 2026.

Neutral/Negative Catalysts

  • The company's financial performance in Q4 2025 showed a significant revenue drop (-89.70% YoY) and negative net income, despite some improvement in EPS and net loss reduction. The options data and technical indicators do not show strong bullish sentiment.

Financial Performance

In Q4 2025, revenue dropped significantly by -89.70% YoY to $121,000. Net income improved to -$81.32M (up 72.68% YoY), and EPS increased to -1.22 (up 71.83% YoY). Gross margin remained at 100%.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Barclays upgraded the stock to Overweight with a price target of $45, citing strong demand for barzolvolimab and faster trial enrollments. Wolfe Research and Morgan Stanley also upgraded the stock with price targets of $44, while Stifel raised its target to $68. Goldman Sachs maintained a Neutral rating with a price target of $34.

Wall Street analysts forecast CLDX stock price to rise
10 Analyst Rating
Wall Street analysts forecast CLDX stock price to rise
9 Buy
0 Hold
1 Sell
Strong Buy
Current: 33.230
sliders
Low
24
Averages
55
High
90
Current: 33.230
sliders
Low
24
Averages
55
High
90
Barclays
Underweight
to
Overweight
upgrade
$24 -> $45
AI Analysis
2026-04-20
Reason
Barclays
Price Target
$24 -> $45
AI Analysis
2026-04-20
upgrade
Underweight
to
Overweight
Reason
Barclays upgraded Celldex to Overweight from Underweight with a price target of $45, up from $24. The firm has conviction in a successful Phase 3 readout in chronic spontaneous urticaria. Barclays says it "can't ignore" the faster than expected enrollment in the Phase 3 EMBARQ trial six months ahead of schedule and the Q4 readout of the study. At a minimum this speaks to the demand and enthusiasm for barzolvolimab, the analyst tells investors in a research note.
Wolfe Research
Peer Perform
to
Outperform
upgrade
$44
2026-03-23
Reason
Wolfe Research
Price Target
$44
2026-03-23
upgrade
Peer Perform
to
Outperform
Reason
Wolfe Research upgraded Celldex to Outperform from Peer Perform with a $44 price target. The firm sees a better catalyst setup for the shares in 2026 relative to 2025. Investors may respond better to Celldex's catalysts this year given the stock's "depressed valuation," the analyst tells investors in a research note.
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