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CERO Overview

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Intellectia

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CERo Therapeutics Holdings, Inc. is an immunotherapy company advancing the development of engineered T cell therapeutics for the treatment of cancer. Its proprietary approach to T cell engineering, which enables it to integrate certain desirable characteristics of both innate and adaptive immunity into a single therapeutic construct, is designed to engage the body’s full immune repertoire to achieve optimized cancer therapy. This novel cellular immunotherapy platform is designed to redirect patient-derived T cells to eliminate tumors by building in engulfment pathways that employ phagocytic mechanisms to destroy cancer cells, creating what the Company refers to as Chimeric Engulfment Receptor T cells (CER-T). Its lead molecule is CER-1236, an autologous T-cell product that targets a novel tumor antigen, TIM-4 ligand. The Company is initiating clinical trials for its lead product candidate, CER-1236, for hematological malignancies.
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Events Timeline

(ET)
2026-02-17
08:20:00
CERo Therapeutics Appoints Eric Francois to Board of Directors
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2026-02-04 (ET)
2026-02-04
09:20:00
CERo Therapeutics Presents CER-1236 Clinical Trial Data
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2026-01-07 (ET)
2026-01-07
09:20:00
CERo Therapeutics Updates on CertainT-1 Clinical Trial Progress
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2025-12-17 (ET)
2025-12-17
08:10:00
CERo Therapeutics Advances CertainT-1 Trial Progress
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2025-12-02 (ET)
2025-12-02
07:40:00
CERo Therapeutics Shares Begin Trading on OTCQB as CERO on December 2, 2025
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2025-11-05 (ET)
2025-11-05
08:21:06
Cero Therapeutics Launches Second Cohort in Phase 1 Study of CER-1236
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2025-11-04 (ET)
2025-11-04
09:10:09
Cero Therapeutics to showcase CER-1236 data at SITC conference
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2025-11-03 (ET)
2025-11-03
08:04:17
Cero Therapeutics Reveals Its Listing on OTC Markets
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News

Newsfilter
9.0
02-04Newsfilter
CERo Therapeutics Presents CER-1236 Clinical Data at ASTCT Meeting
  • Clinical Trial Progress: CERo Therapeutics presented data from its Phase 1 clinical trial of CER-1236 at the ASTCT meeting, demonstrating a 20-70 fold cell expansion, indicating the potential efficacy and safety of this therapy in acute myeloid leukemia (AML) patients.
  • Significant Patient Outcomes: An AML patient achieved over two months of transfusion independence after four infusions of CER-1236, exceeding the commonly used ≥56-day durability benchmark, showcasing the clinical applicability of this therapy.
  • Good Safety Profile: No dose-limiting toxicities or cytokine release syndrome (CRS) were observed in the first four treated patients, supporting further clinical evaluation of CER-1236 in myeloid disease settings.
  • Study Expansion Plans: CERo has amended the trial protocol to include transfusion-dependent myelodysplastic syndromes (TD-MDS), highlighting the broad potential across multiple tumor types and advancing the clinical trial's progress.
Globenewswire
9.0
01-07Globenewswire
CERo Therapeutics Expands Clinical Trial Focus, Reports 61-Day Transfusion-Free Interval
  • Clinical Trial Progress: CERo's CertainT-1 trial reports a 61-day transfusion-free interval, exceeding the common 8-week benchmark, indicating the potential of CER-1236 in treating acute myeloid leukemia (AML) patients, which could enhance the company's competitiveness in cellular immunotherapy.
  • Safety Assessment: During the dose-limiting toxicity observation period for the first cohort, no cases of cytokine release syndrome (CRS) or treatment-related adverse events were reported, demonstrating the safety of CER-1236 and laying a foundation for future clinical applications.
  • Trial Expansion: The company has filed an amendment with the FDA to include advanced myelodysplastic syndrome (MDS) and myelofibrosis (MF) as new cohorts, aiming to broaden treatment indications and enhance market appeal.
  • Future Strategy: CERo plans to discuss trial progress and future strategy in today's analyst call, emphasizing its commitment to patients and shareholders while aiming to drive product development through ongoing dose escalation and safety data collection.
Globenewswire
9.0
2025-12-17Globenewswire
CERo Therapeutics Completes DLT Observation for Cohort 1, Doses First Patient in Cohort 2
  • Clinical Trial Progress: CERo Therapeutics has completed the dose-limiting toxicity (DLT) observation period for the first cohort in its CertainT-1 trial focused on acute myeloid leukemia, marking a significant milestone in the clinical study.
  • Dose Escalation: The first patient in the second cohort received a dose of 4e6 cells/kg of CER-1236, which is four times higher than the 1e6 cells/kg administered to the first cohort, indicating the potential for enhanced therapeutic efficacy.
  • Ongoing Safety Monitoring: An additional dose was provided to the second patient in the first cohort, who remains on study, demonstrating the company's commitment to safety monitoring to ensure patient well-being.
  • Future Outlook: The CEO of CERo emphasized the focus on careful execution of the dose-escalation phase and systematic collection of safety data, laying the groundwork for subsequent clinical trials.
Newsfilter
9.0
2025-12-17Newsfilter
CERo Therapeutics Completes DLT Observation for Cohort 1, Doses First Patient in Cohort 2
  • Clinical Trial Progress: CERo Therapeutics has completed the dose-limiting toxicity (DLT) observation period for the first cohort in its CertainT-1 trial targeting acute myeloid leukemia, delivering a total of 4e6 cells/kg of CER-1236 to the first patient in the second cohort, significantly enhancing the potential efficacy of the treatment.
  • Dose Escalation: The patient in the second cohort received a dose four times higher than that of the first cohort (1e6 cells/kg), which not only aids in assessing the safety of higher doses but also may improve patient response rates, thereby enhancing the company's competitiveness in the cellular immunotherapy space.
  • Ongoing Safety Monitoring: An additional dose was provided to another patient in the first cohort who remains in the study, indicating the company's strong commitment to patient safety during clinical trials, aiming to ensure the reliability and efficacy of the data collected.
  • Innovative Therapeutic Platform: CERo's CER-1236 candidate utilizes a novel cellular immunotherapy platform that integrates key functional attributes of both adaptive and innate immunity, potentially offering new solutions for treating hematologic malignancies and solid tumors, thereby expanding the company's market potential.
TipRanks
4.5
2025-10-30TipRanks
Thursday's Major Stock Market Highlights: Morning News Summary!
  • Investor Insights: Investors can find a curated list of the top stock market stories from Thursday.

  • Source of Information: The information is provided by TipRanks, a platform dedicated to stock market news.

TipRanks
7.0
2025-10-30TipRanks
What Caused CERo Therapeutics Stock to Plummet 80% Today?
  • Delisting Notice: CERo Therapeutics (CERO) stock fell sharply after receiving a delisting notice from Nasdaq for failing to maintain the required stockholders’ equity of at least $2.5 million.

  • Stock Performance: The stock dropped 81.28% in pre-market trading, extending a year-to-date decline of 98.51% and a 90.96% drop over the past 12 months.

  • Future Plans: The company plans to appeal the delisting decision and is preparing to switch to an OTC market listing, though success is uncertain and could negatively impact stock prices.

  • Analyst Ratings: Despite the delisting news, analysts had previously rated CERO as a Moderate Buy, but this rating is expected to change following the recent developments.

Valuation Metrics

The current forward P/E ratio for CERo Therapeutics Holdings Inc (CERO.O) is -0.02, compared to its 5-year average forward P/E of -0.04. For a more detailed relative valuation and DCF analysis to assess CERo Therapeutics Holdings Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-0.04
Current PE
-0.02
Overvalued PE
0.06
Undervalued PE
-0.15

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.01
Current PS
0.10
Overvalued PS
0.13
Undervalued PS
-0.11

Financials

AI Analysis
Annual
Quarterly

Whales Holding CERO

A
Arch Venture Partners, L.P.
Holding
CERO
+11.04%
3M Return

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Frequently Asked Questions

What is CERo Therapeutics Holdings Inc (CERO) stock price today?

The current price of CERO is 0 USD — it has increased 0

What is CERo Therapeutics Holdings Inc (CERO)'s business?

CERo Therapeutics Holdings, Inc. is an immunotherapy company advancing the development of engineered T cell therapeutics for the treatment of cancer. Its proprietary approach to T cell engineering, which enables it to integrate certain desirable characteristics of both innate and adaptive immunity into a single therapeutic construct, is designed to engage the body’s full immune repertoire to achieve optimized cancer therapy. This novel cellular immunotherapy platform is designed to redirect patient-derived T cells to eliminate tumors by building in engulfment pathways that employ phagocytic mechanisms to destroy cancer cells, creating what the Company refers to as Chimeric Engulfment Receptor T cells (CER-T). Its lead molecule is CER-1236, an autologous T-cell product that targets a novel tumor antigen, TIM-4 ligand. The Company is initiating clinical trials for its lead product candidate, CER-1236, for hematological malignancies.

What is the price predicton of CERO Stock?

Wall Street analysts forecast CERO stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for CERO is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is CERo Therapeutics Holdings Inc (CERO)'s revenue for the last quarter?

CERo Therapeutics Holdings Inc revenue for the last quarter amounts to -4.72M USD, decreased -8.24

What is CERo Therapeutics Holdings Inc (CERO)'s earnings per share (EPS) for the last quarter?

CERo Therapeutics Holdings Inc. EPS for the last quarter amounts to USD, decreased

How many employees does CERo Therapeutics Holdings Inc (CERO). have?

CERo Therapeutics Holdings Inc (CERO) has 8 emplpoyees as of March 10 2026.

What is CERo Therapeutics Holdings Inc (CERO) market cap?

Today CERO has the market capitalization of 0.00 USD.