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CBIO Should I Buy

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Intellectia

Should You Buy Crescent Biopharma Inc (CBIO) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
12.550
1 Day change
4.41%
52 Week Range
28.770
Analysis Updated At
2026/03/06
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Crescent Biopharma Inc (CBIO) is not a strong buy at the moment for a beginner investor with a long-term strategy. While the stock has potential in the oncology space with promising pipeline developments and positive analyst ratings, the lack of significant financial growth, absence of recent news catalysts, and neutral trading trends suggest a wait-and-see approach. Additionally, there are no strong proprietary trading signals to support immediate action.

Technical Analysis

The MACD is positive but contracting, RSI is neutral at 48.639, and moving averages are converging, indicating no strong directional trend. The stock is trading near its pivot level of 11.969, with support at 10.863 and resistance at 13.074.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
4
Buy
7

Positive Catalysts

  • and a promising oncology pipeline, including CR-001 and ADC developments. Analysts project significant revenue potential by 2036.

Neutral/Negative Catalysts

  • No recent news or significant trading trends. Financial performance shows no revenue growth, negative EPS (-1.49), and a net loss of -$24.6M. Congress trading data is unavailable.

Financial Performance

In Q3 2025, revenue remained at $0 with no growth. Net income improved by 150.47% YoY but is still negative at -$24.6M. EPS dropped significantly by -90.22% YoY to -1.49.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are bullish with price targets ranging from $22 to $35 and Buy/Overweight ratings. They highlight the potential of CR-001 and the ADC pipeline but note that significant data is 12-15 months away.

Wall Street analysts forecast CBIO stock price to rise
6 Analyst Rating
Wall Street analysts forecast CBIO stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 12.020
sliders
Low
22
Averages
28.2
High
35
Current: 12.020
sliders
Low
22
Averages
28.2
High
35
H.C. Wainwright
Buy
downgrade
$25 -> $22
AI Analysis
2026-03-02
Reason
H.C. Wainwright
Price Target
$25 -> $22
AI Analysis
2026-03-02
downgrade
Buy
Reason
H.C. Wainwright lowered the firm's price target on Crescent Biopharma to $22 from $25 and keeps a Buy rating on the shares.
Piper Sandler
Overweight
initiated
$35
2026-01-28
Reason
Piper Sandler
Price Target
$35
2026-01-28
initiated
Overweight
Reason
Piper Sandler initiated coverage of Crescent Biopharma with an Overweight rating and $35 price target. The firm notes the company's lead asset CR-001 is a PD-1xVEGF bsAb designed to match ivonescimab's cooperativity with potential for subQ administration. A Phase 1/2 is initiating in Q1 2026 to evaluate the asset in several solid tumors. Piper models three indications based on demonstrated efficacy of PD-1xVEGF bsAb in these indications, and cumulatively models about $1.4B in risk-adjusted revenues by 2036. Moreover, the company has a pipeline of ADCs and is at the forefront of this next wave of oncology development combining PD1xVEGF with ADCs.
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