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CBIO Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
OverviewStock Price PredictionTechnicalValuationFinancialsEarningsShould I BuyNews & Events
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Intellectia

Loading chart...

High
13.310
Open
12.130
VWAP
12.60
Vol
444.25K
Mkt Cap
345.84M
Low
11.955
Amount
5.60M
EV/EBITDA(TTM)
--
Total Shares
27.56M
EV
122.04M
EV/OCF(TTM)
--
P/S(TTM)
11.85
Crescent Biopharma, Inc. is a biotechnology company. The Company is focused on advancing the next wave of therapies for cancer patients. The Company’s pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates. The Company’s lead program is CR-001, a tetravalent PD-1 x VEGF bispecific antibody in development for the treatment of solid tumors, and it is also advancing CR-002 and CR-003, antibody drug conjugates (ADCs) with topoisomerase inhibitor payloads. CR-002 and CR-003 are ADCs designed to deliver clinically active cytotoxic drugs known as topoisomerase inhibitors to tumor cells. Each of these programs has the potential to deliver therapeutics with clinical efficacy both as a monotherapy and in combination with CR-001 with significant potential across solid tumor indications.
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Events Timeline

(ET)
2026-02-26
07:40:00
Cash and Cash Equivalents at $213.2 Million, Expected to Fund Operations into 2028
select
2026-02-26
07:40:00
Crescent Reports Q4 Revenue of $10.8M
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2026-02-19 (ET)
2026-02-19
07:40:00
Crescent Biopharma Grants 24,600 Options to Two Employees
select
2026-02-18 (ET)
2026-02-18
07:40:00
Crescent Biopharma Initiates CR-001 Clinical Trial
select
2026-01-07 (ET)
2026-01-07
17:20:00
Crescent Biopharma Files to Sell 19.71M Shares of Common Stock
select
2026-01-05 (ET)
2026-01-05
07:20:00
Crescent Biopharma Secures Regulatory Clearances for CR-001 and CR-003
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News

Newsfilter
5.0
03-06Newsfilter
Crescent Biopharma Grants Stock Options to Employees
  • Stock Options Granted: Crescent Biopharma's Board approved the grant of 45,675 stock options to two non-executive employees on March 5, 2026, as part of the 2025 Employment Inducement Incentive Award Plan, aimed at attracting and retaining talent to enhance the company's competitiveness in cancer treatment.
  • Option Details: The options have an exercise price of $11.33 per share and a 10-year term, with one-fourth vesting on the first anniversary of employment and one-forty-eighth vesting monthly thereafter, ensuring continuous service to realize the incentive's benefits.
  • Compliance Assurance: The stock option grant complies with Nasdaq Listing Rule 5635(c)(4), ensuring that the company adheres to regulations while attracting talent, thereby enhancing investor confidence.
  • Company Vision: Crescent Biopharma aims to become a world-leading oncology company, advancing innovative therapies including a PD-1 x VEGF bispecific antibody, to provide potentially transformative treatment options for cancer patients and strengthen its market position.
Newsfilter
7.5
02-26Newsfilter
Crescent Biopharma Partners with Kelun-Biotech to Expand Oncology Pipeline
  • Strategic Partnership: Crescent has established a collaboration with Sichuan Kelun-Biotech to develop CR-001 (a PD-1 x VEGF bispecific antibody) and multiple antibody-drug conjugates (ADCs), which is expected to accelerate the expansion of its oncology pipeline and significantly enhance market competitiveness.
  • Clinical Trial Progress: The ASCEND global clinical trial has commenced to evaluate CR-001's efficacy in various advanced solid tumors, with preliminary clinical data expected to be reported in Q1 2027, further validating its potential as an immuno-oncology backbone.
  • Funding Support: Crescent completed a $185 million private placement, providing financial backing for key clinical data readouts and ensuring operational funding through 2028, thereby strengthening its R&D capabilities in cancer treatment.
  • Increased R&D Spending: Research and development expenses reached $138.1 million in 2025, a significant increase from 2024, reflecting the company's ongoing investment in projects like CR-001 and CR-002, aimed at rapidly advancing innovative therapies.
Newsfilter
5.0
02-19Newsfilter
Crescent Biopharma Grants Stock Options to Employees
  • Stock Option Grant: Crescent Biopharma approved the grant of 24,600 stock options to two non-executive employees on February 17, 2026, as part of its 2025 Employment Inducement Incentive Award Plan, aimed at attracting and retaining talent to enhance the company's competitiveness in cancer treatment.
  • Option Details: The granted options have a 10-year term with an exercise price of $9.33 per share, complying with Nasdaq listing rules, ensuring that employees receive attractive economic incentives upon accepting employment, thereby promoting stability within the company.
  • Vesting Arrangement: Each employee's options will vest one-fourth on the first anniversary of their start date, with one-forty-eighth vesting monthly thereafter, ensuring continuous service with Crescent to receive long-term incentives, thus enhancing employee loyalty and motivation.
  • Company Vision: Crescent Biopharma aims to become a world-leading oncology company, advancing various innovative therapies, including a PD-1 x VEGF bispecific antibody, with the goal of rapidly developing potentially transformative treatments for a range of solid tumors.
Newsfilter
2.0
02-18Newsfilter
Crescent Biopharma Launches CR-001 Clinical Trial for Solid Tumors
  • Trial Launch: Crescent Biopharma has initiated the ASCEND clinical trial globally to evaluate CR-001, a PD-1 x VEGF bispecific antibody for various solid tumors, with plans to enroll 290 patients, showcasing the company's innovative potential in cancer treatment.
  • Data Reporting Expectations: The company anticipates reporting proof-of-concept data from the ASCEND trial in Q1 2027, including safety and preliminary antitumor activity, aimed at providing robust data support for the further development of CR-001.
  • Multiple Indication Assessment: The ASCEND trial is designed to comprehensively assess the clinical profile of CR-001 in both first-line and previously treated patients, intending to drive the company's development strategy across multiple indications and enhance its market competitiveness.
  • Strategic Collaboration Expansion: Crescent has entered into a strategic collaboration with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd., granting exclusive rights to research and commercialize CR-001 in Greater China, further expanding its influence in the Asian market.
Newsfilter
1.0
02-05Newsfilter
Crescent Biopharma to Participate in Biotech Summit 2026
  • Management Participation: Crescent Biopharma is scheduled to participate in the Guggenheim Emerging Outlook: Biotech Summit on February 12, 2026, in New York, showcasing its latest advancements in cancer therapies, which is expected to attract investor attention and enhance the company's visibility.
  • Live Webcast Availability: The event will be webcast live on the company's website, with a replay accessible for 90 days post-event, enhancing interaction with investors and increasing transparency and trust.
  • Pipeline Overview: Crescent Biopharma's clinical-stage pipeline includes a PD-1 x VEGF bispecific antibody and novel antibody-drug conjugates (ADCs), aiming to rapidly advance cancer treatments that could transform existing therapeutic paradigms.
  • Company Vision: Crescent Biopharma is committed to becoming a world-leading oncology company, leveraging multiple modalities and combination regimens to rapidly advance potentially transformative therapies for a range of solid tumors, demonstrating its strategic ambition in the biotech sector.
Benzinga
6.0
01-21Benzinga
Analysts Bullish on Century Communities, Target Price Set at $92
  • Century Communities Rating: Analyst James McCanless initiated coverage on Century Communities Inc (NYSE:CCS) with a Market Outperform rating and a price target of $92, indicating significant upside from Tuesday's close of $66.26, reflecting confidence in the company's growth prospects.
  • Alumis Inc Rating: Chardan Capital analyst Janani Sundararajan initiated coverage on Alumis Inc (NASDAQ:ALMS) with a Buy rating and a price target of $37, suggesting a 41% upside from Tuesday's close of $26.06, showcasing optimism about its business outlook.
  • Credo Technology Rating: Rosenblatt analyst Mike Genovese initiated coverage on Credo Technology Group Holding Ltd (NASDAQ:CRDO) with a Neutral rating and a price target of $170, indicating potential upside from the current price of $153.22, reflecting a cautious view on its market performance.
  • Crescent Biopharma Rating: Guggenheim analyst Brad Canino initiated coverage on Crescent Biopharma Inc (NASDAQ:CBIO) with a Buy rating and a price target of $35, representing a 150% upside from Tuesday's close of $13.98, indicating strong confidence in its future growth potential.
Wall Street analysts forecast CBIO stock price to rise
6 Analyst Rating
Wall Street analysts forecast CBIO stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
22.00
Averages
28.20
High
35.00
Current: 0.000
sliders
Low
22.00
Averages
28.20
High
35.00
H.C. Wainwright
Buy
downgrade
$25 -> $22
AI Analysis
2026-03-02
Reason
H.C. Wainwright
Price Target
$25 -> $22
AI Analysis
2026-03-02
downgrade
Buy
Reason
H.C. Wainwright lowered the firm's price target on Crescent Biopharma to $22 from $25 and keeps a Buy rating on the shares.
Piper Sandler
Overweight
initiated
$35
2026-01-28
Reason
Piper Sandler
Price Target
$35
2026-01-28
initiated
Overweight
Reason
Piper Sandler initiated coverage of Crescent Biopharma with an Overweight rating and $35 price target. The firm notes the company's lead asset CR-001 is a PD-1xVEGF bsAb designed to match ivonescimab's cooperativity with potential for subQ administration. A Phase 1/2 is initiating in Q1 2026 to evaluate the asset in several solid tumors. Piper models three indications based on demonstrated efficacy of PD-1xVEGF bsAb in these indications, and cumulatively models about $1.4B in risk-adjusted revenues by 2036. Moreover, the company has a pipeline of ADCs and is at the forefront of this next wave of oncology development combining PD1xVEGF with ADCs.
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Valuation Metrics

The current forward P/E ratio for Crescent Biopharma Inc (CBIO.O) is -0.88, compared to its 5-year average forward P/E of -1.68. For a more detailed relative valuation and DCF analysis to assess Crescent Biopharma Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.68
Current PE
-0.88
Overvalued PE
-0.12
Undervalued PE
-3.24

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
25.86
Current PS
64.98
Overvalued PS
62.16
Undervalued PS
-10.43

Financials

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Whales Holding CBIO

V
Vestal Point Capital, LP
Holding
CBIO
+6.94%
3M Return
B
BVF Partners L.P.
Holding
CBIO
+6.57%
3M Return
V
VR Management, LLC
Holding
CBIO
+6.00%
3M Return
F
Fairmount Funds Management LLC
Holding
CBIO
+5.89%
3M Return
T
Tang Capital Management, LLC
Holding
CBIO
+3.59%
3M Return
L
Logos Global Management, L.P.
Holding
CBIO
-0.20%
3M Return

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Frequently Asked Questions

What is Crescent Biopharma Inc (CBIO) stock price today?

The current price of CBIO is 12.55 USD — it has increased 4.41

What is Crescent Biopharma Inc (CBIO)'s business?

Crescent Biopharma, Inc. is a biotechnology company. The Company is focused on advancing the next wave of therapies for cancer patients. The Company’s pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates. The Company’s lead program is CR-001, a tetravalent PD-1 x VEGF bispecific antibody in development for the treatment of solid tumors, and it is also advancing CR-002 and CR-003, antibody drug conjugates (ADCs) with topoisomerase inhibitor payloads. CR-002 and CR-003 are ADCs designed to deliver clinically active cytotoxic drugs known as topoisomerase inhibitors to tumor cells. Each of these programs has the potential to deliver therapeutics with clinical efficacy both as a monotherapy and in combination with CR-001 with significant potential across solid tumor indications.

What is the price predicton of CBIO Stock?

Wall Street analysts forecast CBIO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CBIO is28.20 USD with a low forecast of 22.00 USD and a high forecast of 35.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Crescent Biopharma Inc (CBIO)'s revenue for the last quarter?

Crescent Biopharma Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Crescent Biopharma Inc (CBIO)'s earnings per share (EPS) for the last quarter?

Crescent Biopharma Inc. EPS for the last quarter amounts to -1.49 USD, decreased -90.22

How many employees does Crescent Biopharma Inc (CBIO). have?

Crescent Biopharma Inc (CBIO) has 4 emplpoyees as of March 11 2026.

What is Crescent Biopharma Inc (CBIO) market cap?

Today CBIO has the market capitalization of 345.84M USD.